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Items: 19

1.

Transcriptional profiling of circulating tumor cells in multiple myeloma: a new model to understand disease dissemination.

Garcés JJ, Simicek M, Vicari M, Brozova L, Burgos L, Bezdekova R, Alignani D, Calasanz MJ, Growkova K, Goicoechea I, Agirre X, Pour L, Prosper F, Rios R, Martinez-Lopez J, Millacoy P, Palomera L, Del Orbe R, Perez-Montaña A, Garate S, Blanco L, Lasa M, Maiso P, Flores-Montero J, Sanoja-Flores L, Chyra Z, Vdovin A, Sevcikova T, Jelinek T, Botta C, El Omri H, Keats J, Orfao A, Hajek R, San-Miguel JF, Paiva B.

Leukemia. 2019 Oct 8. doi: 10.1038/s41375-019-0588-4. [Epub ahead of print]

PMID:
31595039
2.

Cytarabine + G-CSF is more effective than cyclophosphamide + G-CSF as a stem cell mobilization regimen in multiple myeloma.

Jelinek T, Adamusova L, Popkova T, Tvrda I, Smejkalova J, Simicek M, Salounova D, Kascak M, Mihalyova J, Plonkova H, Duras J, Navratil M, Hajek R, Koristek Z.

Bone Marrow Transplant. 2019 Jul;54(7):1107-1114. doi: 10.1038/s41409-018-0396-x. Epub 2018 Nov 20.

PMID:
30459429
3.

Mutations in LZTR1 drive human disease by dysregulating RAS ubiquitination.

Steklov M, Pandolfi S, Baietti MF, Batiuk A, Carai P, Najm P, Zhang M, Jang H, Renzi F, Cai Y, Abbasi Asbagh L, Pastor T, De Troyer M, Simicek M, Radaelli E, Brems H, Legius E, Tavernier J, Gevaert K, Impens F, Messiaen L, Nussinov R, Heymans S, Eyckerman S, Sablina AA.

Science. 2018 Dec 7;362(6419):1177-1182. doi: 10.1126/science.aap7607. Epub 2018 Nov 15.

PMID:
30442762
4.

Single-agent venetoclax induces MRD-negative response in relapsed primary plasma cell leukemia with t(11;14).

Jelinek T, Mihalyova J, Kascak M, Duras J, Popkova T, Benkova K, Richterova P, Plonkova H, Zuchnicka J, Broskevicova L, Huvarova L, Cerna L, Growkova K, Simicek M, Havel M, Gumulec J, Navratil M, Koristek Z, Paiva B, Hajek R.

Am J Hematol. 2019 Jan;94(1):E35-E37. doi: 10.1002/ajh.25331. Epub 2018 Nov 25. No abstract available.

PMID:
30370955
5.

Active site alanine mutations convert deubiquitinases into high-affinity ubiquitin-binding proteins.

Morrow ME, Morgan MT, Clerici M, Growkova K, Yan M, Komander D, Sixma TK, Simicek M, Wolberger C.

EMBO Rep. 2018 Oct;19(10). pii: e45680. doi: 10.15252/embr.201745680. Epub 2018 Aug 27.

6.

Venetoclax: A new wave in hematooncology.

Mihalyova J, Jelinek T, Growkova K, Hrdinka M, Simicek M, Hajek R.

Exp Hematol. 2018 May;61:10-25. doi: 10.1016/j.exphem.2018.02.002. Epub 2018 Mar 2. Review.

PMID:
29477371
7.

Current applications of multiparameter flow cytometry in plasma cell disorders.

Jelinek T, Bezdekova R, Zatopkova M, Burgos L, Simicek M, Sevcikova T, Paiva B, Hajek R.

Blood Cancer J. 2018 Jan 19;8(1):e621. doi: 10.1038/bcj.2017.101.

8.

Current applications of multiparameter flow cytometry in plasma cell disorders.

Jelinek T, Bezdekova R, Zatopkova M, Burgos L, Simicek M, Sevcikova T, Paiva B, Hajek R.

Blood Cancer J. 2017 Oct 20;7(10):e617. doi: 10.1038/bcj.2017.90. Review. Erratum in: Blood Cancer J. 2018 Jan 19;8(1):e621.

9.

Diagnostic Tools of Waldenströms Macroglobulinemia - Best Possibilities for Non-invasive and Long-term Disease Monitoring.

Growkova K, Kufová Z, Sevcikova T, Filipová J, Kascak M, Jelínek T, Grosicki S, Barchnicka A, Roziaková Ľ, Mistrík M, Simicek M, Hájek R.

Klin Onkol. Summer 2017;30(Supplementum2):81-91. doi: 10.14735/amko20172S81.

PMID:
28903575
10.

Whole Exome Sequencing of Aberrant Plasma Cells in a Patient with Multiple Myeloma Minimal Residual Disease.

Zatopkova M, Filipová J, Jelínek T, Vojta P, Sevcikova T, Simicek M, Rihova L, Bezdekova R, Growkova K, Kufová Z, Smejkalová J, Hajdúch M, Pour L, Minárik J, Jungová A, Maisnar V, Kryukov F, Hájek R.

Klin Onkol. Summer 2017;30(Supplementum2):75-80. doi: 10.14735/amko20172S75.

PMID:
28903574
11.

Biomarkers in Immunoglobulin Light Chain Amyloidosis.

Kufová Z, Sevcikova T, Growkova K, Vojta P, Filipová J, Adam Z, Pour L, Penka M, Rysava R, Němec P, Brozova L, Vychytilova P, Jurczyszyn A, Grosicki S, Barchnicka A, Hajdúch M, Simicek M, Hájek R.

Klin Onkol. Summer 2017;30(Supplementum2):60-67. doi: 10.14735/amko20172S60.

PMID:
28903572
12.

OTUB1 triggers lung cancer development by inhibiting RAS monoubiquitination.

Baietti MF, Simicek M, Abbasi Asbagh L, Radaelli E, Lievens S, Crowther J, Steklov M, Aushev VN, Martínez García D, Tavernier J, Sablina AA.

EMBO Mol Med. 2016 Mar 1;8(3):288-303. doi: 10.15252/emmm.201505972.

13.

Erratum: Mechanism of phospho-ubiquitin-induced PARKIN activation.

Wauer T, Simicek M, Schubert A, Komander D.

Nature. 2015 Oct 29;526(7575):728. doi: 10.1038/nature15531. Epub 2015 Sep 23. No abstract available.

PMID:
26416742
14.

Mechanism of phospho-ubiquitin-induced PARKIN activation.

Wauer T, Simicek M, Schubert A, Komander D.

Nature. 2015 Aug 20;524(7565):370-4. doi: 10.1038/nature14879. Epub 2015 Jul 10. Erratum in: Nature. 2015 Oct 29;526(7575):728.

15.

Assembly and specific recognition of k29- and k33-linked polyubiquitin.

Michel MA, Elliott PR, Swatek KN, Simicek M, Pruneda JN, Wagstaff JL, Freund SM, Komander D.

Mol Cell. 2015 Apr 2;58(1):95-109. doi: 10.1016/j.molcel.2015.01.042. Epub 2015 Mar 5.

16.

Multiple regulatory roles of the mouse transmembrane adaptor protein NTAL in gene transcription and mast cell physiology.

Polakovicova I, Draberova L, Simicek M, Draber P.

PLoS One. 2014 Aug 25;9(8):e105539. doi: 10.1371/journal.pone.0105539. eCollection 2014.

17.

The deubiquitylase USP33 discriminates between RALB functions in autophagy and innate immune response.

Simicek M, Lievens S, Laga M, Guzenko D, Aushev VN, Kalev P, Baietti MF, Strelkov SV, Gevaert K, Tavernier J, Sablina AA.

Nat Cell Biol. 2013 Oct;15(10):1220-30. doi: 10.1038/ncb2847. Epub 2013 Sep 22.

PMID:
24056301
18.

Loss of PPP2R2A inhibits homologous recombination DNA repair and predicts tumor sensitivity to PARP inhibition.

Kalev P, Simicek M, Vazquez I, Munck S, Chen L, Soin T, Danda N, Chen W, Sablina A.

Cancer Res. 2012 Dec 15;72(24):6414-24. doi: 10.1158/0008-5472.CAN-12-1667. Epub 2012 Oct 18.

19.

The transmembrane adaptor protein NTAL signals to mast cell cytoskeleton via the small GTPase Rho.

Tůmová M, Koffer A, Simíček M, Dráberová L, Dráber P.

Eur J Immunol. 2010 Nov;40(11):3235-45. doi: 10.1002/eji.201040403. Epub 2010 Oct 27.

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