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Items: 7

1.

A broadly applicable cross-linker for aliphatic polymers containing C-H bonds.

Lepage ML, Simhadri C, Liu C, Takaffoli M, Bi L, Crawford B, Milani AS, Wulff JE.

Science. 2019 Nov 15;366(6467):875-878. doi: 10.1126/science.aay6230.

PMID:
31727835
2.

Rational Adaptation of L3MBTL1 Inhibitors to Create Small-Molecule Cbx7 Antagonists.

Simhadri C, Daze KD, Douglas SF, Milosevich N, Monjas L, Dev A, Brown TM, Hirsch AKH, Wulff JE, Hof F.

ChemMedChem. 2019 Aug 6;14(15):1444-1456. doi: 10.1002/cmdc.201900021. Epub 2019 Jul 22.

PMID:
31254321
3.

Structure-Activity Relationships of Cbx7 Inhibitors, Including Selectivity Studies against Other Cbx Proteins.

Simhadri C, Gignac MC, Anderson CJ, Milosevich N, Dheri A, Prashar N, Flemmer RT, Dev A, Henderson TG, Douglas SF, Wulff JE, Hof F.

ACS Omega. 2016 Oct 31;1(4):541-551. doi: 10.1021/acsomega.6b00120. Epub 2016 Oct 12.

4.

Selective Inhibition of CBX6: A Methyllysine Reader Protein in the Polycomb Family.

Milosevich N, Gignac MC, McFarlane J, Simhadri C, Horvath S, Daze KD, Croft CS, Dheri A, Quon TT, Douglas SF, Wulff JE, Paci I, Hof F.

ACS Med Chem Lett. 2015 Dec 7;7(2):139-44. doi: 10.1021/acsmedchemlett.5b00378. eCollection 2016 Feb 11.

5.

Chromodomain antagonists that target the polycomb-group methyllysine reader protein chromobox homolog 7 (CBX7).

Simhadri C, Daze KD, Douglas SF, Quon TT, Dev A, Gignac MC, Peng F, Heller M, Boulanger MJ, Wulff JE, Hof F.

J Med Chem. 2014 Apr 10;57(7):2874-83. doi: 10.1021/jm401487x. Epub 2014 Mar 26.

PMID:
24625057
6.

Dissecting the complex recognition interfaces of potent tetrazole- and pyrrole-based anion binders.

Pinter T, Simhadri C, Hof F.

J Org Chem. 2013 May 17;78(10):4642-8. doi: 10.1021/jo400372c. Epub 2013 May 3.

PMID:
23631741
7.

Multinodular goiter compressing the trachea following open heart surgery.

Sajja LR, Mannam GC, Sompalli S, Simhadri CS, Hasan A.

Asian Cardiovasc Thorac Ann. 2006 Oct;14(5):416-7.

PMID:
17005891

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