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Items: 1 to 50 of 73

1.

Human Semaphorin 3 Variants Link Melanocortin Circuit Development and Energy Balance.

van der Klaauw AA, Croizier S, Mendes de Oliveira E, Stadler LKJ, Park S, Kong Y, Banton MC, Tandon P, Hendricks AE, Keogh JM, Riley SE, Papadia S, Henning E, Bounds R, Bochukova EG, Mistry V, O'Rahilly S, Simerly RB; INTERVAL; UK10K Consortium, Minchin JEN, Barroso I, Jones EY, Bouret SG, Farooqi IS.

Cell. 2019 Feb 7;176(4):729-742.e18. doi: 10.1016/j.cell.2018.12.009. Epub 2019 Jan 17.

2.

Attenuation of diet-induced hypothalamic inflammation following bariatric surgery in female mice.

Herrick MK, Favela KM, Simerly RB, Abumrad NN, Bingham NC.

Mol Med. 2018 Oct 24;24(1):56. doi: 10.1186/s10020-018-0057-y.

3.

Developmental specification of metabolic circuitry.

Elson AE, Simerly RB.

Front Neuroendocrinol. 2015 Oct;39:38-51. doi: 10.1016/j.yfrne.2015.09.003. Epub 2015 Sep 25. Review.

4.

Brain-derived neurotrophic factor is required for axonal growth of selective groups of neurons in the arcuate nucleus.

Liao GY, Bouyer K, Kamitakahara A, Sahibzada N, Wang CH, Rutlin M, Simerly RB, Xu B.

Mol Metab. 2015 Mar 20;4(6):471-82. doi: 10.1016/j.molmet.2015.03.003. eCollection 2015 Jun.

5.

Major epigenetic development distinguishing neuronal and non-neuronal cells occurs postnatally in the murine hypothalamus.

Li G, Zhang W, Baker MS, Laritsky E, Mattan-Hung N, Yu D, Kunde-Ramamoorthy G, Simerly RB, Chen R, Shen L, Waterland RA.

Hum Mol Genet. 2014 Mar 15;23(6):1579-90. doi: 10.1093/hmg/ddt548. Epub 2013 Nov 1.

6.

Postnatal dietary fatty acid composition permanently affects the structure of hypothalamic pathways controlling energy balance in mice.

Schipper L, Bouyer K, Oosting A, Simerly RB, van der Beek EM.

Am J Clin Nutr. 2013 Dec;98(6):1395-401. doi: 10.3945/ajcn.113.069229. Epub 2013 Oct 9.

7.
8.

Distinct roles for specific leptin receptor signals in the development of hypothalamic feeding circuits.

Bouret SG, Bates SH, Chen S, Myers MG Jr, Simerly RB.

J Neurosci. 2012 Jan 25;32(4):1244-52. doi: 10.1523/JNEUROSCI.2277-11.2012.

9.

Leptin grows up and gets a neural network.

Cone RD, Simerly RB.

Neuron. 2011 Jul 14;71(1):4-6. doi: 10.1016/j.neuron.2011.06.033.

10.

Early life programming and neurodevelopmental disorders.

Bale TL, Baram TZ, Brown AS, Goldstein JM, Insel TR, McCarthy MM, Nemeroff CB, Reyes TM, Simerly RB, Susser ES, Nestler EJ.

Biol Psychiatry. 2010 Aug 15;68(4):314-9. doi: 10.1016/j.biopsych.2010.05.028. Review.

11.

The neuroendocrinology and neuroscience of energy balance.

Myers MG Jr, Simerly RB.

Front Neuroendocrinol. 2010 Jan;31(1):1-3. doi: 10.1016/j.yfrne.2009.10.007. Epub 2009 Oct 23. No abstract available.

12.

Estrogen induces caspase-dependent cell death during hypothalamic development.

Waters EM, Simerly RB.

J Neurosci. 2009 Aug 5;29(31):9714-8. doi: 10.1523/JNEUROSCI.0135-09.2009.

13.

Hypothalamic substrates of metabolic imprinting.

Simerly RB.

Physiol Behav. 2008 Apr 22;94(1):79-89. doi: 10.1016/j.physbeh.2007.11.023. Epub 2007 Nov 22. Review.

14.

Hypothalamic neural projections are permanently disrupted in diet-induced obese rats.

Bouret SG, Gorski JN, Patterson CM, Chen S, Levin BE, Simerly RB.

Cell Metab. 2008 Feb;7(2):179-85. doi: 10.1016/j.cmet.2007.12.001.

15.

Development of leptin-sensitive circuits.

Bouret SG, Simerly RB.

J Neuroendocrinol. 2007 Aug;19(8):575-82. Review.

PMID:
17620099
16.

Developmental programming of hypothalamic feeding circuits.

Bouret SG, Simerly RB.

Clin Genet. 2006 Oct;70(4):295-301. Review.

PMID:
16965320
17.
19.

Wired on hormones: endocrine regulation of hypothalamic development.

Simerly RB.

Curr Opin Neurobiol. 2005 Feb;15(1):81-5. Review.

PMID:
15721748
20.

Deletion of Bax eliminates sex differences in the mouse forebrain.

Forger NG, Rosen GJ, Waters EM, Jacob D, Simerly RB, de Vries GJ.

Proc Natl Acad Sci U S A. 2004 Sep 14;101(37):13666-71. Epub 2004 Sep 1.

21.

Trophic action of leptin on hypothalamic neurons that regulate feeding.

Bouret SG, Draper SJ, Simerly RB.

Science. 2004 Apr 2;304(5667):108-10.

22.

Minireview: Leptin and development of hypothalamic feeding circuits.

Bouret SG, Simerly RB.

Endocrinology. 2004 Jun;145(6):2621-6. Epub 2004 Mar 24. Review.

PMID:
15044371
26.

Sexual differentiation of projections from the principal nucleus of the bed nuclei of the stria terminalis.

Gu G, Cornea A, Simerly RB.

J Comp Neurol. 2003 Jun 9;460(4):542-62.

PMID:
12717713
27.

Overexpression of bcl-2 reduces sex differences in neuron number in the brain and spinal cord.

Zup SL, Carrier H, Waters EM, Tabor A, Bengston L, Rosen GJ, Simerly RB, Forger NG.

J Neurosci. 2003 Mar 15;23(6):2357-62.

28.

A model system for study of sex chromosome effects on sexually dimorphic neural and behavioral traits.

De Vries GJ, Rissman EF, Simerly RB, Yang LY, Scordalakes EM, Auger CJ, Swain A, Lovell-Badge R, Burgoyne PS, Arnold AP.

J Neurosci. 2002 Oct 15;22(20):9005-14.

29.

Wired for reproduction: organization and development of sexually dimorphic circuits in the mammalian forebrain.

Simerly RB.

Annu Rev Neurosci. 2002;25:507-36. Epub 2002 Mar 27. Review.

PMID:
12052919
30.

Target-dependent sexual differentiation of a limbic-hypothalamic neural pathway.

Ibanez MA, Gu G, Simerly RB.

J Neurosci. 2001 Aug 1;21(15):5652-9.

31.
32.
33.

Organization and regulation of sexually dimorphic neuroendocrine pathways.

Simerly RB.

Behav Brain Res. 1998 May;92(2):195-203. Review.

PMID:
9638961
35.

Estrogen receptor-dependent sexual differentiation of dopaminergic neurons in the preoptic region of the mouse.

Simerly RB, Zee MC, Pendleton JW, Lubahn DB, Korach KS.

Proc Natl Acad Sci U S A. 1997 Dec 9;94(25):14077-82.

36.

Projections of the sexually dimorphic anteroventral periventricular nucleus in the female rat.

Gu GB, Simerly RB.

J Comp Neurol. 1997 Jul 21;384(1):142-64.

PMID:
9214545
37.

Induction of neuropeptide Y gene expression in the dorsal medial hypothalamic nucleus in two models of the agouti obesity syndrome.

Kesterson RA, Huszar D, Lynch CA, Simerly RB, Cone RD.

Mol Endocrinol. 1997 May;11(5):630-7.

PMID:
9139806
38.
39.

Hormonal regulation of CREB phosphorylation in the anteroventral periventricular nucleus.

Gu G, Rojo AA, Zee MC, Yu J, Simerly RB.

J Neurosci. 1996 May 1;16(9):3035-44.

40.
41.

Organization of projections from the medial nucleus of the amygdala: a PHAL study in the rat.

Canteras NS, Simerly RB, Swanson LW.

J Comp Neurol. 1995 Sep 18;360(2):213-45. Erratum in: J Comp Neurol 1996 May 27;369(2):328-30.

PMID:
8522644
42.

Hormonal regulation of opioid peptide neurons in the anteroventral periventricular nucleus.

Gu G, Simerly RB.

Horm Behav. 1994 Dec;28(4):503-11. Review.

PMID:
7729819
43.

Localization of the melanocortin-4 receptor (MC4-R) in neuroendocrine and autonomic control circuits in the brain.

Mountjoy KG, Mortrud MT, Low MJ, Simerly RB, Cone RD.

Mol Endocrinol. 1994 Oct;8(10):1298-308.

PMID:
7854347
44.
45.

Cell-type-specific expression of catecholamine transporters in the rat brain.

Lorang D, Amara SG, Simerly RB.

J Neurosci. 1994 Aug;14(8):4903-14.

46.

Identification of a receptor for gamma melanotropin and other proopiomelanocortin peptides in the hypothalamus and limbic system.

Roselli-Rehfuss L, Mountjoy KG, Robbins LS, Mortrud MT, Low MJ, Tatro JB, Entwistle ML, Simerly RB, Cone RD.

Proc Natl Acad Sci U S A. 1993 Oct 1;90(19):8856-60.

47.

Distribution and regulation of steroid hormone receptor gene expression in the central nervous system.

Simerly RB.

Adv Neurol. 1993;59:207-26. Review. No abstract available.

PMID:
8380515
48.

Projections of the ventral premammillary nucleus.

Canteras NS, Simerly RB, Swanson LW.

J Comp Neurol. 1992 Oct 8;324(2):195-212.

PMID:
1430329
49.

Connections of the posterior nucleus of the amygdala.

Canteras NS, Simerly RB, Swanson LW.

J Comp Neurol. 1992 Oct 8;324(2):143-79. Erratum in: J Comp Neurol 1993 Feb 22;328(4):604.

PMID:
1430327
50.

The G-protein-coupled receptor kinases beta ARK1 and beta ARK2 are widely distributed at synapses in rat brain.

Arriza JL, Dawson TM, Simerly RB, Martin LJ, Caron MG, Snyder SH, Lefkowitz RJ.

J Neurosci. 1992 Oct;12(10):4045-55.

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