Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 159

1.

HNF1A is a novel oncogene that regulates human pancreatic cancer stem cell properties.

Abel EV, Goto M, Magnuson B, Abraham S, Ramanathan N, Hotaling E, Alaniz AA, Kumar-Sinha C, Dziubinski ML, Urs S, Wang L, Shi J, Waghray M, Ljungman M, Crawford HC, Simeone DM.

Elife. 2018 Aug 3;7. pii: e33947. doi: 10.7554/eLife.33947. [Epub ahead of print]

2.

SHP2 Inhibition Prevents Adaptive Resistance to MEK inhibitors in Multiple Cancer Models.

Fedele C, Ran H, Diskin B, Wei W, Jen J, Geer MJ, Araki K, Ozerdem U, Simeone DM, Miller G, Neel BG, Tang KH.

Cancer Discov. 2018 Jul 25. pii: CD-18-0444. doi: 10.1158/2159-8290.CD-18-0444. [Epub ahead of print]

PMID:
30045908
3.

HIF1-alpha Regulates Acinar Cell Function and Response to Injury in Mouse Pancreas.

Park MJ, Iyer S, Xue X, Bragazzi Cunha J, Gu S, Moons D, Pipe SW, Williams JA, Simeone DM, Shah YM, Omary MB.

Gastroenterology. 2018 May;154(6):1630-1634.e3. doi: 10.1053/j.gastro.2018.01.037. Epub 2018 Feb 1.

PMID:
29409830
4.

An academic career in global surgery: a position paper from the Society of University Surgeons Committee on Academic Global Surgery.

Krishnaswami S, Stephens CQ, Yang GP, Nwomeh BC, Swaroop M, Nadler EP, Holterman AX, Simeone DM, Kingham TP, Merchant N, Orloff SL.

Surgery. 2018 Apr;163(4):954-960. doi: 10.1016/j.surg.2017.10.019. Epub 2017 Dec 15. Review.

PMID:
29254606
5.

Usp9x Promotes Survival in Human Pancreatic Cancer and Its Inhibition Suppresses Pancreatic Ductal Adenocarcinoma In Vivo Tumor Growth.

Pal A, Dziubinski M, Di Magliano MP, Simeone DM, Owens S, Thomas D, Peterson L, Potu H, Talpaz M, Donato NJ.

Neoplasia. 2018 Feb;20(2):152-164. doi: 10.1016/j.neo.2017.11.007. Epub 2017 Dec 14.

6.

High-Throughput Microfluidic Labyrinth for the Label-free Isolation of Circulating Tumor Cells.

Lin E, Rivera-Báez L, Fouladdel S, Yoon HJ, Guthrie S, Wieger J, Deol Y, Keller E, Sahai V, Simeone DM, Burness ML, Azizi E, Wicha MS, Nagrath S.

Cell Syst. 2017 Sep 27;5(3):295-304.e4. doi: 10.1016/j.cels.2017.08.012. Epub 2017 Sep 20.

PMID:
28941584
7.

Microfluidic continuum sorting of sub-populations of tumor cells via surface antibody expression levels.

Jack R, Hussain K, Rodrigues D, Zeinali M, Azizi E, Wicha M, Simeone DM, Nagrath S.

Lab Chip. 2017 Mar 29;17(7):1349-1358. doi: 10.1039/c6lc01496h.

PMID:
28294230
8.

A Gastric Glycoform of MUC5AC Is a Biomarker of Mucinous Cysts of the Pancreas.

Sinha J, Cao Z, Dai J, Tang H, Partyka K, Hostetter G, Simeone DM, Feng Z, Allen PJ, Brand RE, Haab BB.

PLoS One. 2016 Dec 19;11(12):e0167070. doi: 10.1371/journal.pone.0167070. eCollection 2016.

9.

Tissue Classification Using Optical Spectroscopy Accurately Differentiates Cancer and Chronic Pancreatitis.

Wilson RH, Chandra M, Scheiman JM, Lee SY, Lee OE, McKenna BJ, Simeone DM, Taylor JM, Mycek MA.

Pancreas. 2017 Feb;46(2):244-251. doi: 10.1097/MPA.0000000000000732.

10.

Ultra-Specific Isolation of Circulating Tumor Cells Enables Rare-Cell RNA Profiling.

Jack RM, Grafton MM, Rodrigues D, Giraldez MD, Griffith C, Cieslak R, Zeinali M, Kumar Sinha C, Azizi E, Wicha M, Tewari M, Simeone DM, Nagrath S.

Adv Sci (Weinh). 2016 Apr 18;3(9):1600063. eCollection 2016 Sep.

11.

Pancreatic Cancer Chemoprevention Translational Workshop: Meeting Report.

Miller MS, Allen P, Brentnall TA, Goggins M, Hruban RH, Petersen GM, Rao CV, Whitcomb DC, Brand RE, Chari ST, Klein AP, Lubman DM, Rhim AD, Simeone DM, Wolpin BM, Umar A, Srivastava S, Steele VE, Rinaudo JA.

Pancreas. 2016 Sep;45(8):1080-91. doi: 10.1097/MPA.0000000000000705.

12.

A phase I trial of cabozantinib and gemcitabine in advanced pancreatic cancer.

Zhen DB, Griffith KA, Ruch JM, Camphausen K, Savage JE, Kim EJ, Sahai V, Simeone DM, Zalupski MM.

Invest New Drugs. 2016 Dec;34(6):733-739. Epub 2016 Jul 21.

PMID:
27439894
13.

Myeloid cells are required for PD-1/PD-L1 checkpoint activation and the establishment of an immunosuppressive environment in pancreatic cancer.

Zhang Y, Velez-Delgado A, Mathew E, Li D, Mendez FM, Flannagan K, Rhim AD, Simeone DM, Beatty GL, Pasca di Magliano M.

Gut. 2017 Jan;66(1):124-136. doi: 10.1136/gutjnl-2016-312078. Epub 2016 Jul 8.

14.

Opportunities and Challenges for Pancreatic Circulating Tumor Cells.

Nagrath S, Jack RM, Sahai V, Simeone DM.

Gastroenterology. 2016 Sep;151(3):412-26. doi: 10.1053/j.gastro.2016.05.052. Epub 2016 Jun 20. Review.

PMID:
27339829
15.

Localized Pancreatic Cancer: Multidisciplinary Management.

Coveler AL, Herman JM, Simeone DM, Chiorean EG.

Am Soc Clin Oncol Educ Book. 2016;35:e217-26. doi: 10.14694/EDBK_160827. Review.

16.

GM-CSF Mediates Mesenchymal-Epithelial Cross-talk in Pancreatic Cancer.

Waghray M, Yalamanchili M, Dziubinski M, Zeinali M, Erkkinen M, Yang H, Schradle KA, Urs S, Pasca Di Magliano M, Welling TH, Palmbos PL, Abel EV, Sahai V, Nagrath S, Wang L, Simeone DM.

Cancer Discov. 2016 Aug;6(8):886-99. doi: 10.1158/2159-8290.CD-15-0947. Epub 2016 May 16.

17.

Tunable Thermal-Sensitive Polymer-Graphene Oxide Composite for Efficient Capture and Release of Viable Circulating Tumor Cells.

Yoon HJ, Shanker A, Wang Y, Kozminsky M, Jin Q, Palanisamy N, Burness ML, Azizi E, Simeone DM, Wicha MS, Kim J, Nagrath S.

Adv Mater. 2016 Jun;28(24):4891-7. doi: 10.1002/adma.201600658. Epub 2016 Apr 26.

18.

Narcotic Independence After Pancreatic Duct Stenting Predicts Narcotic Independence After Lateral Pancreaticojejunostomy for Chronic Pancreatitis.

Kwon RS, Young BE, Marsteller WF, Lawrence C, Wu BU, Lee LS, Mullady D, Klibansky DA, Gardner TB, Simeone DM.

Pancreas. 2016 Sep;45(8):1126-30. doi: 10.1097/MPA.0000000000000623.

PMID:
27088488
19.

Notch1 and Notch2 receptors regulate mouse and human gastric antral epithelial cell homoeostasis.

Gifford GB, Demitrack ES, Keeley TM, Tam A, La Cunza N, Dedhia PH, Spence JR, Simeone DM, Saotome I, Louvi A, Siebel CW, Samuelson LC.

Gut. 2017 Jun;66(6):1001-1011. doi: 10.1136/gutjnl-2015-310811. Epub 2016 Mar 1.

20.

ATDC/TRIM29 Drives Invasive Bladder Cancer Formation through miRNA-Mediated and Epigenetic Mechanisms.

Palmbos PL, Wang L, Yang H, Wang Y, Leflein J, Ahmet ML, Wilkinson JE, Kumar-Sinha C, Ney GM, Tomlins SA, Daignault S, Kunju LP, Wu XR, Lotan Y, Liebert M, Ljungman ME, Simeone DM.

Cancer Res. 2015 Dec 1;75(23):5155-66. doi: 10.1158/0008-5472.CAN-15-0603. Epub 2015 Oct 15.

21.

ATDC (Ataxia Telangiectasia Group D Complementing) Promotes Radioresistance through an Interaction with the RNF8 Ubiquitin Ligase.

Yang H, Palmbos PL, Wang L, Kim EH, Ney GM, Liu C, Prasad J, Misek DE, Yu X, Ljungman M, Simeone DM.

J Biol Chem. 2015 Nov 6;290(45):27146-57. doi: 10.1074/jbc.M115.665489. Epub 2015 Sep 17.

22.

Definitive Chemoradiation With Full-dose Gemcitabine for Unresectable Pancreatic Cancer: Efficacy of Involved-Field Radiotherapy.

Zhou J, Fang CX, Shen J, Schipper MJ, Zalupski MM, Minter RM, Simeone DM, Hart D, Eagle T, Kimmel GW, Vainshtein J, Lawrence TS, Feng M.

Am J Clin Oncol. 2017 Oct;40(5):517-522. doi: 10.1097/COC.0000000000000200.

PMID:
26165418
23.

Bmi1 is required for the initiation of pancreatic cancer through an Ink4a-independent mechanism.

Bednar F, Schofield HK, Collins MA, Yan W, Zhang Y, Shyam N, Eberle JA, Almada LL, Olive KP, Bardeesy N, Fernandez-Zapico ME, Nakada D, Simeone DM, Morrison SJ, Pasca di Magliano M.

Carcinogenesis. 2015 Jul;36(7):730-8. doi: 10.1093/carcin/bgv058. Epub 2015 May 4.

24.

Early detection of sporadic pancreatic cancer: summative review.

Chari ST, Kelly K, Hollingsworth MA, Thayer SP, Ahlquist DA, Andersen DK, Batra SK, Brentnall TA, Canto M, Cleeter DF, Firpo MA, Gambhir SS, Go VL, Hines OJ, Kenner BJ, Klimstra DS, Lerch MM, Levy MJ, Maitra A, Mulvihill SJ, Petersen GM, Rhim AD, Simeone DM, Srivastava S, Tanaka M, Vinik AI, Wong D.

Pancreas. 2015 Jul;44(5):693-712. doi: 10.1097/MPA.0000000000000368. Review.

25.

Large-scale identification of core-fucosylated glycopeptide sites in pancreatic cancer serum using mass spectrometry.

Tan Z, Yin H, Nie S, Lin Z, Zhu J, Ruffin MT, Anderson MA, Simeone DM, Lubman DM.

J Proteome Res. 2015 Apr 3;14(4):1968-78. doi: 10.1021/acs.jproteome.5b00068. Epub 2015 Mar 9.

26.

ATDC induces an invasive switch in KRAS-induced pancreatic tumorigenesis.

Wang L, Yang H, Abel EV, Ney GM, Palmbos PL, Bednar F, Zhang Y, Leflein J, Waghray M, Owens S, Wilkinson JE, Prasad J, Ljungman M, Rhim AD, Pasca di Magliano M, Simeone DM.

Genes Dev. 2015 Jan 15;29(2):171-83. doi: 10.1101/gad.253591.114.

27.

CD44 regulates pancreatic cancer invasion through MT1-MMP.

Jiang W, Zhang Y, Kane KT, Collins MA, Simeone DM, di Magliano MP, Nguyen KT.

Mol Cancer Res. 2015 Jan;13(1):9-15. doi: 10.1158/1541-7786.MCR-14-0076. Epub 2015 Jan 7.

28.

Expansion of CTCs from early stage lung cancer patients using a microfluidic co-culture model.

Zhang Z, Shiratsuchi H, Lin J, Chen G, Reddy RM, Azizi E, Fouladdel S, Chang AC, Lin L, Jiang H, Waghray M, Luker G, Simeone DM, Wicha MS, Beer DG, Ramnath N, Nagrath S.

Oncotarget. 2014 Dec 15;5(23):12383-97.

29.

Quantitative analysis of single amino acid variant peptides associated with pancreatic cancer in serum by an isobaric labeling quantitative method.

Nie S, Yin H, Tan Z, Anderson MA, Ruffin MT, Simeone DM, Lubman DM.

J Proteome Res. 2014 Dec 5;13(12):6058-66. doi: 10.1021/pr500934u. Epub 2014 Nov 24.

30.

Tumor-associated macrophages are a useful biomarker to predict recurrence after surgical resection of nonfunctional pancreatic neuroendocrine tumors.

Wei IH, Harmon CM, Arcerito M, Cheng DF, Minter RM, Simeone DM.

Ann Surg. 2014 Dec;260(6):1088-94. doi: 10.1097/SLA.0000000000000262.

31.

A pilot study of diffusion-weighted MRI in patients undergoing neoadjuvant chemoradiation for pancreatic cancer.

Cuneo KC, Chenevert TL, Ben-Josef E, Feng MU, Greenson JK, Hussain HK, Simeone DM, Schipper MJ, Anderson MA, Zalupski MM, Al-Hawary M, Galban CJ, Rehemtulla A, Feng FY, Lawrence TS, Ross BD.

Transl Oncol. 2014 Oct 24;7(5):644-9. doi: 10.1016/j.tranon.2014.07.005. eCollection 2014 Oct.

32.

Proteins associated with pancreatic cancer survival in patients with resectable pancreatic ductal adenocarcinoma.

Chen R, Dawson DW, Pan S, Ottenhof NA, de Wilde RF, Wolfgang CL, May DH, Crispin DA, Lai LA, Lay AR, Waghray M, Wang S, McIntosh MW, Simeone DM, Maitra A, Brentnall TA.

Lab Invest. 2015 Jan;95(1):43-55. doi: 10.1038/labinvest.2014.128. Epub 2014 Oct 27.

33.

Pilot clinical trial of hedgehog pathway inhibitor GDC-0449 (vismodegib) in combination with gemcitabine in patients with metastatic pancreatic adenocarcinoma.

Kim EJ, Sahai V, Abel EV, Griffith KA, Greenson JK, Takebe N, Khan GN, Blau JL, Craig R, Balis UG, Zalupski MM, Simeone DM.

Clin Cancer Res. 2014 Dec 1;20(23):5937-5945. doi: 10.1158/1078-0432.CCR-14-1269. Epub 2014 Oct 2.

34.

Tumor-associated macrophages produce interleukin 6 and signal via STAT3 to promote expansion of human hepatocellular carcinoma stem cells.

Wan S, Zhao E, Kryczek I, Vatan L, Sadovskaya A, Ludema G, Simeone DM, Zou W, Welling TH.

Gastroenterology. 2014 Dec;147(6):1393-404. doi: 10.1053/j.gastro.2014.08.039. Epub 2014 Aug 30.

35.

A radial flow microfluidic device for ultra-high-throughput affinity-based isolation of circulating tumor cells.

Murlidhar V, Zeinali M, Grabauskiene S, Ghannad-Rezaie M, Wicha MS, Simeone DM, Ramnath N, Reddy RM, Nagrath S.

Small. 2014 Dec 10;10(23):4895-904. doi: 10.1002/smll.201400719. Epub 2014 Jul 29.

36.

Recent advances in pancreatic surgery.

Bednar F, Simeone DM.

Curr Opin Gastroenterol. 2014 Sep;30(5):518-23. doi: 10.1097/MOG.0000000000000096. Review.

PMID:
25010685
37.

Microfluidic device (ExoChip) for on-chip isolation, quantification and characterization of circulating exosomes.

Kanwar SS, Dunlay CJ, Simeone DM, Nagrath S.

Lab Chip. 2014 Jun 7;14(11):1891-900. doi: 10.1039/c4lc00136b. Epub 2014 Apr 10.

38.

The Notch pathway is important in maintaining the cancer stem cell population in pancreatic cancer.

Abel EV, Kim EJ, Wu J, Hynes M, Bednar F, Proctor E, Wang L, Dziubinski ML, Simeone DM.

PLoS One. 2014 Mar 19;9(3):e91983. doi: 10.1371/journal.pone.0091983. eCollection 2014.

39.

Glycoprotein biomarker panel for pancreatic cancer discovered by quantitative proteomics analysis.

Nie S, Lo A, Wu J, Zhu J, Tan Z, Simeone DM, Anderson MA, Shedden KA, Ruffin MT, Lubman DM.

J Proteome Res. 2014 Apr 4;13(4):1873-84. doi: 10.1021/pr400967x. Epub 2014 Mar 10.

40.

ATDC/TRIM29 phosphorylation by ATM/MAPKAP kinase 2 mediates radioresistance in pancreatic cancer cells.

Wang L, Yang H, Palmbos PL, Ney G, Detzler TA, Coleman D, Leflein J, Davis M, Zhang M, Tang W, Hicks JK, Helchowski CM, Prasad J, Lawrence TS, Xu L, Yu X, Canman CE, Ljungman M, Simeone DM.

Cancer Res. 2014 Mar 15;74(6):1778-88. doi: 10.1158/0008-5472.CAN-13-2289. Epub 2014 Jan 27.

41.

Antibody against CD44s inhibits pancreatic tumor initiation and postradiation recurrence in mice.

Li L, Hao X, Qin J, Tang W, He F, Smith A, Zhang M, Simeone DM, Qiao XT, Chen ZN, Lawrence TS, Xu L.

Gastroenterology. 2014 Apr;146(4):1108-18. doi: 10.1053/j.gastro.2013.12.035. Epub 2014 Jan 5.

42.

Pancreatic ductal adenocarcinoma radiology reporting template: consensus statement of the society of abdominal radiology and the american pancreatic association.

Al-Hawary MM, Francis IR, Chari ST, Fishman EK, Hough DM, Lu DS, Macari M, Megibow AJ, Miller FH, Mortele KJ, Merchant NB, Minter RM, Tamm EP, Sahani DV, Simeone DM.

Gastroenterology. 2014 Jan;146(1):291-304.e1. doi: 10.1053/j.gastro.2013.11.004.

PMID:
24355035
43.

Pancreatic ductal adenocarcinoma radiology reporting template: consensus statement of the Society of Abdominal Radiology and the American Pancreatic Association.

Al-Hawary MM, Francis IR, Chari ST, Fishman EK, Hough DM, Lu DS, Macari M, Megibow AJ, Miller FH, Mortele KJ, Merchant NB, Minter RM, Tamm EP, Sahani DV, Simeone DM.

Radiology. 2014 Jan;270(1):248-60. doi: 10.1148/radiol.13131184.

PMID:
24354378
44.

Novel neutralizing hedgehog antibody MEDI-5304 exhibits antitumor activity by inhibiting paracrine hedgehog signaling.

Michaud NR, Wang Y, McEachern KA, Jordan JJ, Mazzola AM, Hernandez A, Jalla S, Chesebrough JW, Hynes MJ, Belmonte MA, Wang L, Kang JS, Jovanovic J, Laing N, Jenkins DW, Hurt E, Liang M, Frantz C, Hollingsworth RE, Simeone DM, Blakey DC, Bedian V.

Mol Cancer Ther. 2014 Feb;13(2):386-98. doi: 10.1158/1535-7163.MCT-13-0420. Epub 2013 Dec 16.

45.

Label-free relative quantification of alpha-2-macroglobulin site-specific core-fucosylation in pancreatic cancer by LC-MS/MS.

Lin Z, Yin H, Lo A, Ruffin MT, Anderson MA, Simeone DM, Lubman DM.

Electrophoresis. 2014 Aug;35(15):2108-15. doi: 10.1002/elps.201300376. Epub 2013 Dec 27.

46.

Minutes of the business meeting of the American Pancreatic Association, Friday, November 2, 2012, Miami, Florida.

Liddle RA, Freeman M, Simeone DM, Saluja AK, Castillo CF, Maitra A, Pandol SJ, Go VL.

Pancreas. 2013 Nov;42(8):1333-4. doi: 10.1097/MPA.0b013e3182a99936. No abstract available.

47.

HAb18G/CD147 promotes pSTAT3-mediated pancreatic cancer development via CD44s.

Li L, Tang W, Wu X, Karnak D, Meng X, Thompson R, Hao X, Li Y, Qiao XT, Lin J, Fuchs J, Simeone DM, Chen ZN, Lawrence TS, Xu L.

Clin Cancer Res. 2013 Dec 15;19(24):6703-15. doi: 10.1158/1078-0432.CCR-13-0621. Epub 2013 Oct 16.

48.

Sensitive capture of circulating tumour cells by functionalized graphene oxide nanosheets.

Yoon HJ, Kim TH, Zhang Z, Azizi E, Pham TM, Paoletti C, Lin J, Ramnath N, Wicha MS, Hayes DF, Simeone DM, Nagrath S.

Nat Nanotechnol. 2013 Oct;8(10):735-41. doi: 10.1038/nnano.2013.194. Epub 2013 Sep 29.

49.

Breast cancer metastases to the pancreas.

Bednar F, Scheiman JM, McKenna BJ, Simeone DM.

J Gastrointest Surg. 2013 Oct;17(10):1826-31. doi: 10.1007/s11605-013-2291-5. Epub 2013 Aug 6. Review.

PMID:
23918083
50.

SOX2 promotes dedifferentiation and imparts stem cell-like features to pancreatic cancer cells.

Herreros-Villanueva M, Zhang JS, Koenig A, Abel EV, Smyrk TC, Bamlet WR, de Narvajas AA, Gomez TS, Simeone DM, Bujanda L, Billadeau DD.

Oncogenesis. 2013 Aug 5;2:e61. doi: 10.1038/oncsis.2013.23.

Supplemental Content

Loading ...
Support Center