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A screen for genetic suppressor elements of hepatitis C virus identifies a supercharged protein inhibitor of viral replication.

Simeon RL, Chen Z.

PLoS One. 2013 Dec 31;8(12):e84022. doi: 10.1371/journal.pone.0084022. eCollection 2013.


Discovery and characterization of a new cell-penetrating protein.

Simeon RL, Chamoun AM, McMillin T, Chen Z.

ACS Chem Biol. 2013 Dec 20;8(12):2678-87. doi: 10.1021/cb4004089. Epub 2013 Oct 7.


Phenothiazines inhibit hepatitis C virus entry, likely by increasing the fluidity of cholesterol-rich membranes.

Chamoun-Emanuelli AM, Pecheur EI, Simeon RL, Huang D, Cremer PS, Chen Z.

Antimicrob Agents Chemother. 2013 Jun;57(6):2571-81. doi: 10.1128/AAC.02593-12. Epub 2013 Mar 25.


Creation and characterization of a cell-death reporter cell line for hepatitis C virus infection.

Chen Z, Simeon RL, Chockalingam K, Rice CM.

Antiviral Res. 2010 May;86(2):220-3. doi: 10.1016/j.antiviral.2010.02.321. Epub 2010 Feb 25.


A cell protection screen reveals potent inhibitors of multiple stages of the hepatitis C virus life cycle.

Chockalingam K, Simeon RL, Rice CM, Chen Z.

Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3764-9. doi: 10.1073/pnas.0915117107. Epub 2010 Feb 8.

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