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Items: 1 to 50 of 291

1.

Identification of a Unique Resorcylic Acid Lactone Derivative That Targets Both Lymphangiogenesis and Angiogenesis.

Han Y, Sengupta S, Lee BJ, Cho H, Kim J, Choi HG, Dash U, Kim JH, Kim ND, Kim JH, Sim T.

J Med Chem. 2019 Oct 7. doi: 10.1021/acs.jmedchem.9b01025. [Epub ahead of print]

PMID:
31513411
2.

Identification of Novel Resorcinol Amide Derivatives as Potent and Specific Pyruvate Dehydrogenase Kinase (PDHK) Inhibitors.

Cho H, Shin I, Cho K, Yoon H, Yoo EK, Kim MJ, Park S, Lee IK, Kim ND, Sim T.

J Med Chem. 2019 Sep 26;62(18):8461-8479. doi: 10.1021/acs.jmedchem.9b00565. Epub 2019 Sep 13.

PMID:
31469962
3.

Raman-Based in Situ Monitoring of Changes in Molecular Signatures during Mitochondrially Mediated Apoptosis.

Shin HJ, Lee JH, Kim YD, Shin I, Sim T, Lim DK.

ACS Omega. 2019 May 6;4(5):8188-8195. doi: 10.1021/acsomega.9b00629. eCollection 2019 May 31.

4.

Identification of 1H-pyrazolo[3,4-b]pyridine derivatives as potent ALK-L1196M inhibitors.

Nam Y, Hwang D, Kim N, Seo HS, Selim KB, Sim T.

J Enzyme Inhib Med Chem. 2019 Dec;34(1):1426-1438. doi: 10.1080/14756366.2019.1639694.

5.

Analysis to determine cost-effectiveness of procalcitonin-guided antibiotic use in adult patients with suspected bacterial infection and sepsis.

Collins CD, Brockhaus K, Sim T, Suneja A, Malani AN.

Am J Health Syst Pharm. 2019 Aug 1;76(16):1219-1225. doi: 10.1093/ajhp/zxz129.

PMID:
31369118
6.

Antidepressant Prescribing Patterns in Heart Failure Patients at Residential Aged Care Facilities in Australia: A Cross-sectional Study.

Marashdeh RAM, Parsons R, Sim TF.

J Res Pharm Pract. 2019 Apr-Jun;8(2):69-74. doi: 10.4103/jrpp.JRPP_18_63.

7.

A cross-sectional survey of enhanced and extended professional services in community pharmacies: A pharmacy perspective.

Sim TF, Wright B, Hattingh L, Parsons R, Sunderland B, Czarniak P.

Res Social Adm Pharm. 2019 Jul 4. pii: S1551-7411(18)30915-X. doi: 10.1016/j.sapharm.2019.07.001. [Epub ahead of print]

PMID:
31300355
8.

Successful implementation and provision of enhanced and extended pharmacy services.

Hattingh L, Sim TF, Sunderland B, Czarniak P.

Res Social Adm Pharm. 2019 Jun 26. pii: S1551-7411(19)30281-5. doi: 10.1016/j.sapharm.2019.06.015. [Epub ahead of print]

PMID:
31272922
9.

A nano-sized blending system comprising identical triblock copolymers with different hydrophobicity for fabrication of an anticancer drug nanovehicle with high stability and solubilizing capacity.

Hoang NH, Sim T, Lim C, Le TN, Han SM, Lee ES, Youn YS, Oh KT.

Int J Nanomedicine. 2019 May 17;14:3629-3644. doi: 10.2147/IJN.S191126. eCollection 2019.

10.

Synthesis and structure activity relationships of a series of 4-amino-1H-pyrazoles as covalent inhibitors of CDK14.

Ferguson FM, Doctor ZM, Ficarro SB, Marto JA, Kim ND, Sim T, Gray NS.

Bioorg Med Chem Lett. 2019 Aug 1;29(15):1985-1993. doi: 10.1016/j.bmcl.2019.05.024. Epub 2019 May 23.

PMID:
31175010
11.

A Bcr-Abl Inhibitor GNF-2 Attenuates Inflammatory Activation of Glia and Chronic Pain.

Song GJ, Rahman MH, Jha MK, Gupta DP, Park SH, Kim JH, Lee SH, Lee IK, Sim T, Bae YC, Lee WH, Suk K.

Front Pharmacol. 2019 May 20;10:543. doi: 10.3389/fphar.2019.00543. eCollection 2019.

12.

Pretreated Oenanthe Javanica extract increases anti-inflammatory cytokines, attenuates gliosis, and protects hippocampal neurons following transient global cerebral ischemia in gerbils.

Park JH, Kim IH, Ahn JH, Noh YH, Kim SS, Lee TK, Lee JC, Shin BN, Sim TH, Lee HS, Cho JH, Hwang IK, Kang IJ, Kim JD, Won MH.

Neural Regen Res. 2019 Sep;14(9):1536-1543. doi: 10.4103/1673-5374.255973.

13.

Complementary medicines use amongst elective surgery patients at a public tertiary hospital: A prospective observational cohort study in Australia.

Guilmetdinov EF, Al-Khalaf M, Bhatt J, Parsons R, Sim TF.

Complement Ther Clin Pract. 2019 May;35:284-289. doi: 10.1016/j.ctcp.2019.03.012. Epub 2019 Mar 15.

PMID:
31003671
14.

Leveraging Compound Promiscuity to Identify Targetable Cysteines within the Kinome.

Rao S, Gurbani D, Du G, Everley RA, Browne CM, Chaikuad A, Tan L, Schröder M, Gondi S, Ficarro SB, Sim T, Kim ND, Berberich MJ, Knapp S, Marto JA, Westover KD, Sorger PK, Gray NS.

Cell Chem Biol. 2019 Jun 20;26(6):818-829.e9. doi: 10.1016/j.chembiol.2019.02.021. Epub 2019 Apr 11.

PMID:
30982749
15.

Influence of cognitive impairment on pain assessment and management in the emergency department: A retrospective cross-sectional study.

Jones J, Sim TF, Parsons R, Hughes J.

Emerg Med Australas. 2019 Apr 5. doi: 10.1111/1742-6723.13294. [Epub ahead of print]

PMID:
30953419
16.

Discovery of Covalent CDK14 Inhibitors with Pan-TAIRE Family Specificity.

Ferguson FM, Doctor ZM, Ficarro SB, Browne CM, Marto JA, Johnson JL, Yaron TM, Cantley LC, Kim ND, Sim T, Berberich MJ, Kalocsay M, Sorger PK, Gray NS.

Cell Chem Biol. 2019 Jun 20;26(6):804-817.e12. doi: 10.1016/j.chembiol.2019.02.015. Epub 2019 Mar 28.

PMID:
30930164
17.

Assessing the Impact of a Pulmonary Embolism Response Team and Treatment Protocol on Patients Presenting With Acute Pulmonary Embolism.

Jen WY, Kristanto W, Teo L, Phua J, Yip HS, MacLaren G, Teoh K, Sim TB, Loh J, Ong CC, Chee YL, Kojodjojo P.

Heart Lung Circ. 2019 Mar 12. pii: S1443-9506(19)30267-7. doi: 10.1016/j.hlc.2019.02.190. [Epub ahead of print]

PMID:
30910512
18.

Development of a Selective CDK7 Covalent Inhibitor Reveals Predominant Cell-Cycle Phenotype.

Olson CM, Liang Y, Leggett A, Park WD, Li L, Mills CE, Elsarrag SZ, Ficarro SB, Zhang T, Düster R, Geyer M, Sim T, Marto JA, Sorger PK, Westover KD, Lin CY, Kwiatkowski N, Gray NS.

Cell Chem Biol. 2019 Jun 20;26(6):792-803.e10. doi: 10.1016/j.chembiol.2019.02.012. Epub 2019 Mar 21.

PMID:
30905681
19.

A tale of two countries: Singaporean and Chinese parents' emotion socialisation during childhood and the relation to adolescents' emotion regulation.

Yeo GH, Cheah CSL, Sim TN.

Int J Psychol. 2019 Mar 8. doi: 10.1002/ijop.12576. [Epub ahead of print]

PMID:
30847904
20.

Early predictors for the diagnosis of liver abscess in the emergency department.

Chia DWJ, Kuan WS, Ho WH, Sim TB, Chua MT.

Intern Emerg Med. 2019 Aug;14(5):783-791. doi: 10.1007/s11739-019-02061-z. Epub 2019 Mar 7.

PMID:
30847718
21.

A nano-complex system to overcome antagonistic photo-chemo combination cancer therapy.

Lim C, Moon J, Sim T, Won WR, Lee ES, Youn YS, Oh KT.

J Control Release. 2019 Feb 10;295:164-173. doi: 10.1016/j.jconrel.2018.12.043. Epub 2018 Dec 25.

PMID:
30592982
22.

Exploring influences on pharmacists' and students' ethical reasoning in a changing practice landscape in Australia.

Sim TF, Sunderland B, Hattingh HL.

Int J Clin Pharm. 2019 Feb;41(1):280-288. doi: 10.1007/s11096-018-0774-x. Epub 2018 Dec 22.

PMID:
30578471
23.

Procaspase activating compound 1 controls tetracycline repressor-regulated gene expression system.

Song C, Kim N, Park M, Lee J, Oh KB, Sim T.

Biosci Rep. 2019 Jan 8;39(1). pii: BSR20180793. doi: 10.1042/BSR20180793. Print 2019 Jan 31.

24.

Medical cannabis: A needs analysis for people with epilepsy.

Kerai A, Sim TF, Emmerton L.

Complement Ther Clin Pract. 2018 Nov;33:43-48. doi: 10.1016/j.ctcp.2018.08.003. Epub 2018 Aug 8.

PMID:
30396625
25.

Design, synthesis, and biological evaluation of novel aminopyrimidinylisoindolines as AXL kinase inhibitors.

Choi MJ, Roh EJ, Hur W, Lee SH, Sim T, Oh CH, Lee SH, Kim JS, Yoo KH.

Bioorg Med Chem Lett. 2018 Dec 15;28(23-24):3761-3765. doi: 10.1016/j.bmcl.2018.10.013. Epub 2018 Oct 11.

PMID:
30340900
26.

First SAR Study for Overriding NRAS Mutant Driven Acute Myeloid Leukemia.

Cho H, Shin I, Ju E, Choi S, Hur W, Kim H, Hong E, Kim ND, Choi HG, Gray NS, Sim T.

J Med Chem. 2018 Sep 27;61(18):8353-8373. doi: 10.1021/acs.jmedchem.8b00882. Epub 2018 Sep 11.

PMID:
30153003
27.

Cyclic RGD-conjugated Pluronic® blending system for active, targeted drug delivery.

Lim C, Moon J, Sim T, Hoang NH, Won WR, Lee ES, Youn YS, Choi HG, Oh K, Oh KT.

Int J Nanomedicine. 2018 Aug 10;13:4627-4639. doi: 10.2147/IJN.S171794. eCollection 2018.

28.

Structural and Atropisomeric Factors Governing the Selectivity of Pyrimido-benzodiazipinones as Inhibitors of Kinases and Bromodomains.

Wang J, Erazo T, Ferguson FM, Buckley DL, Gomez N, Muñoz-Guardiola P, Diéguez-Martínez N, Deng X, Hao M, Massefski W, Fedorov O, Offei-Addo NK, Park PM, Dai L, DiBona A, Becht K, Kim ND, McKeown MR, Roberts JM, Zhang J, Sim T, Alessi DR, Bradner JE, Lizcano JM, Blacklow SC, Qi J, Xu X, Gray NS.

ACS Chem Biol. 2018 Sep 21;13(9):2438-2448. doi: 10.1021/acschembio.7b00638. Epub 2018 Aug 31.

29.

Landmark Free Face Attribute Prediction.

Li J, Zhao F, Feng J, Roy S, Yan S, Sim T.

IEEE Trans Image Process. 2018 May 21. doi: 10.1109/TIP.2018.2839521. [Epub ahead of print]

PMID:
29994309
30.

Development of Highly Potent and Selective Steroidal Inhibitors and Degraders of CDK8.

Hatcher JM, Wang ES, Johannessen L, Kwiatkowski N, Sim T, Gray NS.

ACS Med Chem Lett. 2018 Mar 18;9(6):540-545. doi: 10.1021/acsmedchemlett.8b00011. eCollection 2018 Jun 14.

31.

Analysis of sensory system aspects of postural stability during quiet standing in adolescent idiopathic scoliosis patients.

Sim T, Yoo H, Lee D, Suh SW, Yang JH, Kim H, Mun JH.

J Neuroeng Rehabil. 2018 Jun 22;15(1):54. doi: 10.1186/s12984-018-0395-6.

32.

Health-Promoting Lifestyles Among Health Care Workers in a Postdisaster Area: A Cross-sectional Study.

Yang W, Sim T, Cui K, Zhang J, Yang Y, Ma X.

Disaster Med Public Health Prep. 2019 Apr;13(2):230-235. doi: 10.1017/dmp.2018.36. Epub 2018 Jun 18.

PMID:
29909799
33.

The Protective Effects of a Synthetic Geranyl Acetophenone in a Cellular Model of TNF-α-Induced Pulmonary Epithelial Barrier Dysfunction.

Sim TY, Harith HH, Tham CL, Md Hashim NF, Shaari K, Sulaiman MR, Israf DA.

Molecules. 2018 Jun 5;23(6). pii: E1355. doi: 10.3390/molecules23061355.

34.

Development of a docetaxel micellar formulation using poly(ethylene glycol)-polylactide-poly(ethylene glycol) (PEG-PLA-PEG) with successful reconstitution for tumor targeted drug delivery.

Sim T, Kim JE, Hoang NH, Kang JK, Lim C, Kim DS, Lee ES, Youn YS, Choi HG, Han HK, Weon KY, Oh KT.

Drug Deliv. 2018 Nov;25(1):1362-1371. doi: 10.1080/10717544.2018.1477865.

35.

Successful Treatment of Cerebral Toxoplasmosis Using Pyrimethamine Oral Solution Compounded From Inexpensive Bulk Powder.

Hodgson HA, Sim T, Gonzalez H, Aziz M, Rhee Y, Lewis PO, Jhobalia N, Shields B, Wang SK.

Open Forum Infect Dis. 2018 Apr 18;5(4):ofy055. doi: 10.1093/ofid/ofy055. eCollection 2018 Apr.

36.

A Novel Detection Model and Its Optimal Features to Classify Falls from Low- and High-Acceleration Activities of Daily Life Using an Insole Sensor System.

Cates B, Sim T, Heo HM, Kim B, Kim H, Mun JH.

Sensors (Basel). 2018 Apr 17;18(4). pii: E1227. doi: 10.3390/s18041227.

37.

Noninvasive Ventilation as a Temporizing Measure in Critical Fixed Central Airway Obstruction: A Case Report.

Cheng LTW, Sim TB, Kuan WS.

J Emerg Med. 2018 May;54(5):615-618. doi: 10.1016/j.jemermed.2017.12.059. Epub 2018 Feb 23.

PMID:
29482923
38.

Improved Dissolution and Oral Bioavailability of Celecoxib by a Dry Elixir System.

Cho KH, Jee JP, Yang DA, Kim ST, Kang D, Kim DY, Sim T, Park SY, Kim K, Jang DJ.

J Nanosci Nanotechnol. 2018 Feb 1;18(2):1482-1486. doi: 10.1166/jnn.2018.14885.

PMID:
29448619
39.

Removing Control of Cyclodextrin-Drug Complexes Using High Affinity Molecule.

Kim YH, Kim ST, Jee JP, Kim DY, Kang D, Kim K, Park SY, Sim T, Cho KH, Jang DJ.

J Nanosci Nanotechnol. 2018 Feb 1;18(2):898-901. doi: 10.1166/jnn.2018.14877.

PMID:
29448513
40.

Management of dyspepsia-The role of the ED Observation unit to optimize patient outcomes.

Chor WPD, Yong PXL, Lim LL, Chai CY, Sim TB, Kuan WS.

Am J Emerg Med. 2018 Oct;36(10):1733-1737. doi: 10.1016/j.ajem.2018.01.057. Epub 2018 Feb 3.

PMID:
29444751
41.

Improvement in Door-to-Needle Time in Patients with Acute Ischemic Stroke via a Simple Stroke Activation Protocol.

Tan BYQ, Ngiam NJH, Sunny S, Kong WY, Tam H, Sim TB, Leong BSH, Bhartendu C, Paliwal PR, Seet RCS, Chan BPL, Teoh HL, Sharma VK, Yeo LLL.

J Stroke Cerebrovasc Dis. 2018 Jun;27(6):1539-1545. doi: 10.1016/j.jstrokecerebrovasdis.2018.01.005. Epub 2018 Feb 13.

PMID:
29422380
42.

De novo-based transcriptome profiling of male-sterile and fertile watermelon lines.

Rhee SJ, Kwon T, Seo M, Jang YJ, Sim TY, Cho S, Han SW, Lee GP.

PLoS One. 2017 Nov 2;12(11):e0187147. doi: 10.1371/journal.pone.0187147. eCollection 2017.

43.

Acute Changes in Plasma Total Tau Levels Are Independent of Subconcussive Head Impacts in College Football Players.

Kawata K, Rubin LH, Wesley L, Lee JH, Sim T, Takahagi M, Bellamy A, Tierney R, Langford D.

J Neurotrauma. 2018 Jan 15;35(2):260-266. doi: 10.1089/neu.2017.5376. Epub 2017 Dec 18.

PMID:
29073820
44.

Amphiphilic small peptides for delivery of plasmid DNAs and siRNAs.

Bang EK, Cho H, Jeon SS, Tran NL, Lim DK, Hur W, Sim T.

Chem Biol Drug Des. 2018 Feb;91(2):575-587. doi: 10.1111/cbdd.13122. Epub 2017 Nov 13.

PMID:
29052961
45.

HM10660A, a long-acting hIFN-α-2b, is a potent candidate for the treatment of hepatitis C through an enhanced biological half-life.

Bae S, Sim T, Lim C, Kim D, Lee J, Park Y, Jung S, Choi I, Kwon S, Oh KT.

Int J Pharm. 2017 Dec 20;534(1-2):89-96. doi: 10.1016/j.ijpharm.2017.09.074. Epub 2017 Oct 2.

PMID:
28982547
46.
47.

Female reproductive success and calf survival in a North Sea coastal bottlenose dolphin (Tursiops truncatus) population.

Robinson KP, Sim TMC, Culloch RM, Bean TS, Cordoba Aguilar I, Eisfeld SM, Filan M, Haskins GN, Williams G, Pierce GJ.

PLoS One. 2017 Sep 20;12(9):e0185000. doi: 10.1371/journal.pone.0185000. eCollection 2017.

48.

Structural Revision of Baulamycin A and Structure-Activity Relationships of Baulamycin A Derivatives.

Sengupta S, Bae M, Oh DC, Dash U, Kim HJ, Song WY, Shin I, Sim T.

J Org Chem. 2017 Dec 15;82(24):12947-12966. doi: 10.1021/acs.joc.7b01719. Epub 2017 Oct 2.

PMID:
28903000
49.

A charge-reversible nanocarrier using PEG-PLL (-g-Ce6, DMA)-PLA for photodynamic therapy.

Lim C, Sim T, Hoang NH, Jung CE, Lee ES, Youn YS, Oh KT.

Int J Nanomedicine. 2017 Aug 24;12:6185-6196. doi: 10.2147/IJN.S142912. eCollection 2017.

50.

Characterization and pharmacokinetic study of itraconazole solid dispersions prepared by solvent-controlled precipitation and spray-dry methods.

Sim T, Lim C, Lee JW, Kim DW, Kim Y, Kim M, Choi S, Choi HG, Lee ES, Kim KS, Kang W, Oh KT.

J Pharm Pharmacol. 2017 Dec;69(12):1707-1715. doi: 10.1111/jphp.12805. Epub 2017 Sep 5.

PMID:
28872678

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