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Items: 1 to 50 of 180

1.

B1 B cell progenitors.

Ghosn E, Dorshkind K, Herzenberg LA, Holodick N, Kantor A, Montecino-Rodriguez E, Rothstein TL, Silverman GJ, Yang Y, Yoder MC, Yoshimoto M.

Science. 2019 Apr 19;364(6437):248. doi: 10.1126/science.aax6784. Epub 2019 Apr 18. No abstract available.

PMID:
31000655
2.

Tissue resident and follicular Treg cell differentiation is regulated by CRAC channels.

Vaeth M, Wang YH, Eckstein M, Yang J, Silverman GJ, Lacruz RS, Kannan K, Feske S.

Nat Commun. 2019 Mar 12;10(1):1183. doi: 10.1038/s41467-019-08959-8.

3.

Lupus nephritis is linked to disease-activity associated expansions and immunity to a gut commensal.

Azzouz D, Omarbekova A, Heguy A, Schwudke D, Gisch N, Rovin BH, Caricchio R, Buyon JP, Alekseyenko AV, Silverman GJ.

Ann Rheum Dis. 2019 Jul;78(7):947-956. doi: 10.1136/annrheumdis-2018-214856. Epub 2019 Feb 19.

4.

The microbiome in SLE pathogenesis.

Silverman GJ.

Nat Rev Rheumatol. 2019 Feb;15(2):72-74. doi: 10.1038/s41584-018-0152-z. No abstract available.

PMID:
30607012
5.

Essential Domain-Dependent Roles Within Soluble IgG for in vivo Superantigen Properties of Staphylococcal Protein A: Resolving the B-Cell Superantigen Paradox.

Ulloa-Morales AJ, Goodyear CS, Silverman GJ.

Front Immunol. 2018 Sep 19;9:2011. doi: 10.3389/fimmu.2018.02011. eCollection 2018.

6.

Hierarchy of human IgG recognition within the Staphylococcus aureus immunome.

Radke EE, Brown SM, Pelzek AJ, Fulmer Y, Hernandez DN, Torres VJ, Thomsen IP, Chiang WK, Miller AO, Shopsin B, Silverman GJ.

Sci Rep. 2018 Sep 5;8(1):13296. doi: 10.1038/s41598-018-31424-3.

7.

The Microbiome and Systemic Lupus Erythematosus.

Rosenbaum JT, Silverman GJ.

N Engl J Med. 2018 Jun 7;378(23):2236-2237. doi: 10.1056/NEJMcibr1804368. No abstract available.

PMID:
29874543
8.

Immune checkpoint inhibitors and the union of bugs against cancer.

Silverman GJ, Azzouz DF, Mor A.

Kidney Int. 2018 May;93(5):1030-1032. doi: 10.1016/j.kint.2018.03.003. No abstract available.

9.

Human Memory B Cells Targeting Staphylococcus aureus Exotoxins Are Prevalent with Skin and Soft Tissue Infection.

Pelzek AJ, Shopsin B, Radke EE, Tam K, Ueberheide BM, Fenyö D, Brown SM, Li Q, Rubin A, Fulmer Y, Chiang WK, Hernandez DN, El Bannoudi H, Sause WE, Sommerfield A, Thomsen IP, Miller AO, Torres VJ, Silverman GJ.

MBio. 2018 Mar 13;9(2). pii: e02125-17. doi: 10.1128/mBio.02125-17.

10.

Autoimmune reactivity to malondialdehyde adducts in systemic lupus erythematosus is associated with disease activity and nephritis.

Hardt U, Larsson A, Gunnarsson I, Clancy RM, Petri M, Buyon JP, Silverman GJ, Svenungsson E, Grönwall C.

Arthritis Res Ther. 2018 Feb 26;20(1):36. doi: 10.1186/s13075-018-1530-2.

11.

Is Gut Microbial LPS a Potential Trigger of Juvenile Idiopathic Arthritis?

Azzouz DF, Silverman GJ.

J Rheumatol. 2017 Nov;44(11):1569-1571. doi: 10.3899/jrheum.170791. Epub 2017 Nov 1. No abstract available.

PMID:
29093074
12.

Depressed serum IgM levels in SLE are restricted to defined subgroups.

Grönwall C, Hardt U, Gustafsson JT, Elvin K, Jensen-Urstad K, Kvarnström M, Grosso G, Rönnelid J, Padykov L, Gunnarsson I, Silverman GJ, Svenungsson E.

Clin Immunol. 2017 Oct;183:304-315. doi: 10.1016/j.clim.2017.09.013. Epub 2017 Sep 15.

PMID:
28919518
13.

Unbiased RACE-Based Massive Parallel Surveys of Human IgA Antibody Repertoires.

El Bannoudi H, Anquetil C, Braunstein MJ, Pond SLK, Silverman GJ.

Methods Mol Biol. 2017;1643:45-73. doi: 10.1007/978-1-4939-7180-0_5.

PMID:
28667529
14.

Autoreactivity to malondialdehyde-modifications in rheumatoid arthritis is linked to disease activity and synovial pathogenesis.

Grönwall C, Amara K, Hardt U, Krishnamurthy A, Steen J, Engström M, Sun M, Ytterberg AJ, Zubarev RA, Scheel-Toellner D, Greenberg JD, Klareskog L, Catrina AI, Malmström V, Silverman GJ.

J Autoimmun. 2017 Nov;84:29-45. doi: 10.1016/j.jaut.2017.06.004. Epub 2017 Jun 21.

PMID:
28647488
15.

Targeting the programmed cell death-1 pathway in rheumatoid arthritis.

Sandigursky S, Silverman GJ, Mor A.

Autoimmun Rev. 2017 Aug;16(8):767-773. doi: 10.1016/j.autrev.2017.05.025. Epub 2017 May 29. Review.

16.

Persistence of Disease-Associated Anti-Citrullinated Protein Antibody-Expressing Memory B Cells in Rheumatoid Arthritis in Clinical Remission.

Pelzek AJ, Grönwall C, Rosenthal P, Greenberg JD, McGeachy M, Moreland L, Rigby WFC, Silverman GJ.

Arthritis Rheumatol. 2017 Jun;69(6):1176-1186. doi: 10.1002/art.40053. Epub 2017 May 3.

17.

miRNAs Are Essential for the Regulation of the PI3K/AKT/FOXO Pathway and Receptor Editing during B Cell Maturation.

Coffre M, Benhamou D, Rieß D, Blumenberg L, Snetkova V, Hines MJ, Chakraborty T, Bajwa S, Jensen K, Chong MMW, Getu L, Silverman GJ, Blelloch R, Littman DR, Calado D, Melamed D, Skok JA, Rajewsky K, Koralov SB.

Cell Rep. 2016 Nov 22;17(9):2271-2285. doi: 10.1016/j.celrep.2016.11.006.

18.

Modulation of natural IgM autoantibodies to oxidative stress-related neo-epitopes on apoptotic cells in newborns of mothers with anti-Ro autoimmunity.

Grönwall C, Clancy RM, Getu L, Lloyd KA, Siegel DL, Reed JH, Buyon JP, Silverman GJ.

J Autoimmun. 2016 Sep;73:30-41. doi: 10.1016/j.jaut.2016.05.014. Epub 2016 Jun 8.

19.

Role of Natural Autoantibodies in Ugandans With Rheumatic Heart Disease and HIV.

Huck DM, Okello E, Mirembe G, Ssinabulya I, Zidar DA, Silverman GJ, Getu L, Nowacki AS, Calabrese LH, Salata RA, Longenecker CT.

EBioMedicine. 2016 Feb 6;5:161-6. doi: 10.1016/j.ebiom.2016.02.006. eCollection 2016 Mar.

20.

Anti-carbamylated Protein Antibody Levels Correlate with Anti-Sa (Citrullinated Vimentin) Antibody Levels in Rheumatoid Arthritis.

Challener GJ, Jones JD, Pelzek AJ, Hamilton BJ, Boire G, de Brum-Fernandes AJ, Masetto A, Carrier N, Ménard HA, Silverman GJ, Rigby WFC.

J Rheumatol. 2016 Feb;43(2):273-281. doi: 10.3899/jrheum.150179. Epub 2015 Dec 15.

21.

Efficacy and Safety of Tabalumab, an Anti-B-Cell-Activating Factor Monoclonal Antibody, in a Heterogeneous Rheumatoid Arthritis Population: Results From a Randomized, Placebo-Controlled, Phase 3 Trial (FLEX-O).

Genovese MC, Silverman GJ, Emery P, Gupta RC, Gill A, Veenhuizen M, Xie L, Komocsar WJ, Berclaz PY, Lee C.

J Clin Rheumatol. 2015 Aug;21(5):231-8. doi: 10.1097/RHU.0000000000000276.

PMID:
26203826
22.

Assigning and visualizing germline genes in antibody repertoires.

Frost SD, Murrell B, Hossain AS, Silverman GJ, Pond SL.

Philos Trans R Soc Lond B Biol Sci. 2015 Sep 5;370(1676). pii: 20140240. doi: 10.1098/rstb.2014.0240.

23.

Protective natural autoantibodies to apoptotic cells: evidence of convergent selection of recurrent innate-like clones.

Silverman GJ.

Ann N Y Acad Sci. 2015 Dec;1362:164-75. doi: 10.1111/nyas.12788. Epub 2015 May 18. Review.

24.

Erratum to: Analysis of Programmed Death-1 in Patients with Psoriatic Arthritis.

Peled M, Strazza M, Azoulay-Alfaguter I, Silverman GJ, Scher JU, Mor A.

Inflammation. 2015 Aug;38(4):1580. doi: 10.1007/s10753-015-0165-6. No abstract available.

PMID:
25847627
25.

T cell chemokine receptor patterns as pathogenic signatures in autoimmunity.

Strazza M, Azoulay-Alfaguter I, Silverman GJ, Mor A.

Discov Med. 2015 Feb;19(103):117-25. Review.

26.

Analysis of Programmed Death-1 in Patients with Psoriatic Arthritis.

Peled M, Strazza M, Azoulay-Alfaguter I, Silverman GJ, Scher JU, Mor A.

Inflammation. 2015 Aug;38(4):1573-9. doi: 10.1007/s10753-015-0132-2. Erratum in: Inflammation. 2015 Aug;38(4):1580. Silverman, Gregg J [added]; Scher, Jose U [added].

PMID:
25663558
27.

Programmed death-1 pathway in cancer and autoimmunity.

Pedoeem A, Azoulay-Alfaguter I, Strazza M, Silverman GJ, Mor A.

Clin Immunol. 2014 Jul;153(1):145-52. doi: 10.1016/j.clim.2014.04.010. Epub 2014 Apr 26. Review.

PMID:
24780173
28.

Selection of apoptotic cell specific human antibodies from adult bone marrow.

Grönwall C, Charles ED, Dustin LB, Rader C, Silverman GJ.

PLoS One. 2014 Apr 23;9(4):e95999. doi: 10.1371/journal.pone.0095999. eCollection 2014.

29.

Relation of carotid plaque with natural IgM antibodies in patients with systemic lupus erythematosus.

Grönwall C, Reynolds H, Kim JK, Buyon J, Goldberg JD, Clancy RM, Silverman GJ.

Clin Immunol. 2014 Jul;153(1):1-7. doi: 10.1016/j.clim.2014.03.017. Epub 2014 Apr 3.

30.

Rheumatoid arthritis clinical benefits from abatacept, cytokine blockers, and rituximab are all linked to modulation of memory B cell responses.

Silverman GJ, Pelzek A.

J Rheumatol. 2014 May;41(5):825-8. doi: 10.3899/jrheum.140022. Epub 2014 Apr 1. No abstract available.

31.

Natural IgM: beneficial autoantibodies for the control of inflammatory and autoimmune disease.

Grönwall C, Silverman GJ.

J Clin Immunol. 2014 Jul;34 Suppl 1:S12-21. doi: 10.1007/s10875-014-0025-4. Epub 2014 Apr 2. Review.

32.

Protective autoantibodies in the rheumatic diseases: lessons for therapy.

Silverman GJ, Vas J, Grönwall C.

Nat Rev Rheumatol. 2013 May;9(5):291-300. doi: 10.1038/nrrheum.2013.30. Epub 2013 Mar 19. Review.

PMID:
23507902
33.

Fundamental roles of the innate-like repertoire of natural antibodies in immune homeostasis.

Vas J, Grönwall C, Silverman GJ.

Front Immunol. 2013 Feb 5;4:4. doi: 10.3389/fimmu.2013.00004. eCollection 2013.

34.

MAPK phosphatase-1 is required for regulatory natural autoantibody-mediated inhibition of TLR responses.

Grönwall C, Chen Y, Vas J, Khanna S, Thiel S, Corr M, Kono DH, Silverman GJ.

Proc Natl Acad Sci U S A. 2012 Nov 27;109(48):19745-50. doi: 10.1073/pnas.1211868109. Epub 2012 Nov 8.

35.

Naturally occurring autoantibodies to apoptotic cells.

Elkon KB, Silverman GJ.

Adv Exp Med Biol. 2012;750:14-26. doi: 10.1007/978-1-4614-3461-0_2.

PMID:
22903663
36.

In vivo VL-targeted microbial superantigen induced global shifts in the B cell repertoire.

Grönwall C, Kosakovsky Pond SL, Young JA, Silverman GJ.

J Immunol. 2012 Jul 15;189(2):850-9. doi: 10.4049/jimmunol.1200245. Epub 2012 Jun 13.

37.

Natural antibody to apoptotic cell membranes inhibits the proinflammatory properties of lupus autoantibody immune complexes.

Vas J, Grönwall C, Marshak-Rothstein A, Silverman GJ.

Arthritis Rheum. 2012 Oct;64(10):3388-98. doi: 10.1002/art.34537.

38.

Protective Roles of Natural IgM Antibodies.

Grönwall C, Vas J, Silverman GJ.

Front Immunol. 2012 Apr 4;3:66. doi: 10.3389/fimmu.2012.00066. eCollection 2012.

39.

IgM autoantibodies to distinct apoptosis-associated antigens correlate with protection from cardiovascular events and renal disease in patients with SLE.

Grönwall C, Akhter E, Oh C, Burlingame RW, Petri M, Silverman GJ.

Clin Immunol. 2012 Mar;142(3):390-8. doi: 10.1016/j.clim.2012.01.002. Epub 2012 Jan 14.

40.

Natural IgM in immune equilibrium and harnessing their therapeutic potential.

Kaveri SV, Silverman GJ, Bayry J.

J Immunol. 2012 Feb 1;188(3):939-45. doi: 10.4049/jimmunol.1102107. Review.

41.

Co-opting endogenous immunoglobulin for the regulation of inflammation and osteoclastogenesis in humans and mice.

MacLellan LM, Montgomery J, Sugiyama F, Kitson SM, Thümmler K, Silverman GJ, Beers SA, Nibbs RJ, McInnes IB, Goodyear CS.

Arthritis Rheum. 2011 Dec;63(12):3897-907. doi: 10.1002/art.30629.

42.

Inflammation and autoantibody markers identify rheumatoid arthritis patients with enhanced clinical benefit following rituximab treatment.

Lal P, Su Z, Holweg CT, Silverman GJ, Schwartzman S, Kelman A, Read S, Spaniolo G, Monroe JG, Behrens TW, Townsend MJ.

Arthritis Rheum. 2011 Dec;63(12):3681-91. doi: 10.1002/art.30596.

43.

WASp-deficient B cells play a critical, cell-intrinsic role in triggering autoimmunity.

Becker-Herman S, Meyer-Bahlburg A, Schwartz MA, Jackson SW, Hudkins KL, Liu C, Sather BD, Khim S, Liggitt D, Song W, Silverman GJ, Alpers CE, Rawlings DJ.

J Exp Med. 2011 Sep 26;208(10):2033-42. doi: 10.1084/jem.20110200. Epub 2011 Aug 29.

44.

Development of anti-CD20 therapy for multiple sclerosis.

Bartok B, Silverman GJ.

Exp Cell Res. 2011 May 15;317(9):1312-8. doi: 10.1016/j.yexcr.2011.04.002. Epub 2011 Apr 12. Review.

45.

Regulatory natural autoantibodies to apoptotic cells: pallbearers and protectors.

Silverman GJ.

Arthritis Rheum. 2011 Mar;63(3):597-602. doi: 10.1002/art.30140. No abstract available.

46.

Rethinking the red wolf disease: does Protein S suppress systemic lupus erythematosus clinical activity?

Silverman GJ.

Arthritis Res Ther. 2010;12(5):144. doi: 10.1186/ar3162. Epub 2010 Oct 27.

47.
48.

Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus.

Kono DH, Haraldsson MK, Lawson BR, Pollard KM, Koh YT, Du X, Arnold CN, Baccala R, Silverman GJ, Beutler BA, Theofilopoulos AN.

Proc Natl Acad Sci U S A. 2009 Jul 21;106(29):12061-6. doi: 10.1073/pnas.0905441106. Epub 2009 Jul 2.

49.

Regulation of dendritic cells and macrophages by an anti-apoptotic cell natural antibody that suppresses TLR responses and inhibits inflammatory arthritis.

Chen Y, Khanna S, Goodyear CS, Park YB, Raz E, Thiel S, Grönwall C, Vas J, Boyle DL, Corr M, Kono DH, Silverman GJ.

J Immunol. 2009 Jul 15;183(2):1346-59. doi: 10.4049/jimmunol.0900948. Epub 2009 Jun 29.

50.

IgM antibodies to apoptosis-associated determinants recruit C1q and enhance dendritic cell phagocytosis of apoptotic cells.

Chen Y, Park YB, Patel E, Silverman GJ.

J Immunol. 2009 May 15;182(10):6031-43. doi: 10.4049/jimmunol.0804191.

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