Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 440

1.

Pharmacogenomics and Placebo Response in a Randomized Clinical Trial in Asthma.

Wang RS, Croteau-Chonka DC, Silverman EK, Loscalzo J, Weiss ST, Hall KT.

Clin Pharmacol Ther. 2019 Sep 26. doi: 10.1002/cpt.1646. [Epub ahead of print]

PMID:
31557306
2.

Microbiome-Transcriptome Interactions Related to Severity of Respiratory Syncytial Virus Infection.

Sonawane AR, Tian L, Chu CY, Qiu X, Wang L, Holden-Wiltse J, Grier A, Gill SR, Caserta MT, Falsey AR, Topham DJ, Walsh EE, Mariani TJ, Weiss ST, Silverman EK, Glass K, Liu YY.

Sci Rep. 2019 Sep 25;9(1):13824. doi: 10.1038/s41598-019-50217-w.

3.

Peripheral Blood Gene Expression Signatures of Eosinophilic Chronic Obstructive Pulmonary Disease.

Yun JH, Chase R, Parker MM, Saferali A, Castaldi PJ, Silverman EK, Hersh CP.

Am J Respir Cell Mol Biol. 2019 Sep;61(3):398-401. doi: 10.1165/rcmb.2019-0112LE. No abstract available.

PMID:
31469299
4.

Identification of an emphysema-associated genetic variant near TGFB2 with regulatory effects in lung fibroblasts.

Parker MM, Hao Y, Guo F, Pham B, Chase R, Platig J, Cho MH, Hersh CP, Thannickal VJ, Crapo J, Washko G, Randell SH, Silverman EK, San José Estépar R, Zhou X, Castaldi PJ.

Elife. 2019 Jul 25;8. pii: e42720. doi: 10.7554/eLife.42720.

5.

Identifying Smoking-Related Disease on Lung Cancer Screening CT Scans: Increasing the Value.

Regan EA, Lowe KE, Make BJ, Lynch DA, Kinney GL, Budoff MJ, Mao SS, Dyer D, Curtis JL, Bowler RP, Han MK, Beaty TH, Hokanson JE, Kern E, Humphries S, Curran-Everett D, van Beek EJR, Silverman EK, Crapo JD, Finigan JH; COPDGene® Investigators.

Chronic Obstr Pulm Dis. 2019 Jul 24;6(3):233-245. doi: 10.15326/jcopdf.6.3.2018.0142.

6.

Overlap of Genetic Risk Between Interstitial Lung Abnormalities and Idiopathic Pulmonary Fibrosis.

Hobbs BD, Putman RK, Araki T, Nishino M, Gudmundsson G, Gudnason V, Eiriksdottir G, Zilhao Nogueira NR, Dupuis J, Xu H, O'Connor GT, Manichaikul A, Nguyen J, Podolanczuk AJ, Madahar P, Rotter JI, Lederer DJ, Barr RG, Rich SS, Ampleford EJ, Ortega VE, Peters SP, O'Neal WK, Newell JD Jr, Bleecker ER, Meyers DA, Allen RJ, Oldham JM, Ma SF, Noth I, Jenkins RG, Maher TM, Hubbard RB, Wain LV, Fingerlin TE, Schwartz DA, Washko GR, Rosas IO, Silverman EK, Hatabu H, Cho MH, Hunninghake GM; COPDGene Investigators, ECLIPSE Investigators, SPIROMICS Research Group, and UK ILD Consortium.

Am J Respir Crit Care Med. 2019 Jul 24. doi: 10.1164/rccm.201903-0511OC. [Epub ahead of print]

PMID:
31339356
7.

DSP variants may be associated with longitudinal change in quantitative emphysema.

Kim W, Cho MH, Sakornsakolpat P, Lynch DA, Coxson HO, Tal-Singer R, Silverman EK, Beaty TH.

Respir Res. 2019 Jul 19;20(1):160. doi: 10.1186/s12931-019-1097-8.

8.

Subtyping COPD by Using Visual and Quantitative CT Imaging Features.

Park J, Hobbs BD, Crapo JD, Make BJ, Regan EA, Humphries S, Carey VJ, Lynch DA, Silverman EK; COPDGene Investigators.

Chest. 2019 Jul 5. pii: S0012-3692(19)31255-3. doi: 10.1016/j.chest.2019.06.015. [Epub ahead of print]

PMID:
31283919
9.

metaFARVAT: An Efficient Tool for Meta-Analysis of Family-Based, Case-Control, and Population-Based Rare Variant Association Studies.

Wang L, Lee S, Qiao D, Cho MH, Silverman EK, Lange C, Won S.

Front Genet. 2019 Jun 19;10:572. doi: 10.3389/fgene.2019.00572. eCollection 2019.

10.

Analysis of genetically driven alternative splicing identifies FBXO38 as a novel COPD susceptibility gene.

Saferali A, Yun JH, Parker MM, Sakornsakolpat P, Chase RP, Lamb A, Hobbs BD, Boezen MH, Dai X, de Jong K, Beaty TH, Wei W, Zhou X, Silverman EK, Cho MH, Castaldi PJ, Hersh CP; COPDGene Investigators; International COPD Genetics Consortium Investigators.

PLoS Genet. 2019 Jul 3;15(7):e1008229. doi: 10.1371/journal.pgen.1008229. eCollection 2019 Jul.

11.

Turning subtypes into disease axes to improve prediction of COPD progression.

Chen J, Cho M, Silverman EK, Hokanson JE, Kinney GL, Crapo JD, Rennard S, Dy J, Castaldi P.

Thorax. 2019 Sep;74(9):906-909. doi: 10.1136/thoraxjnl-2018-213005. Epub 2019 Jun 12.

PMID:
31189730
12.

Subjects with diffuse idiopathic skeletal hyperostosis have an increased burden of coronary artery disease: An evaluation in the COPDGene cohort.

Oudkerk SF, Mohamed Hoesein FAA, PThM Mali W, Öner FC, Verlaan JJ, de Jong PA, Kinney GL, Hokanson J, Lynch D, Silverman EK, Budoff MJ, Regan EA.

Atherosclerosis. 2019 Aug;287:24-29. doi: 10.1016/j.atherosclerosis.2019.05.030. Epub 2019 May 30.

PMID:
31181416
13.

Clinical Epidemiology of COPD: Insights From 10 Years of the COPDGene Study.

Maselli DJ, Bhatt SP, Anzueto A, Bowler RP, DeMeo DL, Diaz AA, Dransfield MT, Fawzy A, Foreman MG, Hanania NA, Hersh CP, Kim V, Kinney GL, Putcha N, Wan ES, Wells JM, Westney GE, Young KA, Silverman EK, Han MK, Make BJ.

Chest. 2019 Aug;156(2):228-238. doi: 10.1016/j.chest.2019.04.135. Epub 2019 May 30. Review.

PMID:
31154041
14.

It's more than low BMI: prevalence of cachexia and associated mortality in COPD.

McDonald MN, Wouters EFM, Rutten E, Casaburi R, Rennard SI, Lomas DA, Bamman M, Celli B, Agusti A, Tal-Singer R, Hersh CP, Dransfield M, Silverman EK.

Respir Res. 2019 May 22;20(1):100. doi: 10.1186/s12931-019-1073-3.

15.

Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.

Shrine N, Guyatt AL, Erzurumluoglu AM, Jackson VE, Hobbs BD, Melbourne CA, Batini C, Fawcett KA, Song K, Sakornsakolpat P, Li X, Boxall R, Reeve NF, Obeidat M, Zhao JH, Wielscher M; Understanding Society Scientific Group, Weiss S, Kentistou KA, Cook JP, Sun BB, Zhou J, Hui J, Karrasch S, Imboden M, Harris SE, Marten J, Enroth S, Kerr SM, Surakka I, Vitart V, Lehtimäki T, Allen RJ, Bakke PS, Beaty TH, Bleecker ER, Bossé Y, Brandsma CA, Chen Z, Crapo JD, Danesh J, DeMeo DL, Dudbridge F, Ewert R, Gieger C, Gulsvik A, Hansell AL, Hao K, Hoffman JD, Hokanson JE, Homuth G, Joshi PK, Joubert P, Langenberg C, Li X, Li L, Lin K, Lind L, Locantore N, Luan J, Mahajan A, Maranville JC, Murray A, Nickle DC, Packer R, Parker MM, Paynton ML, Porteous DJ, Prokopenko D, Qiao D, Rawal R, Runz H, Sayers I, Sin DD, Smith BH, Artigas MS, Sparrow D, Tal-Singer R, Timmers PRHJ, Van den Berge M, Whittaker JC, Woodruff PG, Yerges-Armstrong LM, Troyanskaya OG, Raitakari OT, Kähönen M, Polašek O, Gyllensten U, Rudan I, Deary IJ, Probst-Hensch NM, Schulz H, James AL, Wilson JF, Stubbe B, Zeggini E, Jarvelin MR, Wareham N, Silverman EK, Hayward C, Morris AP, Butterworth AS, Scott RA, Walters RG, Meyers DA, Cho MH, Strachan DP, Hall IP, Tobin MD, Wain LV.

Nat Genet. 2019 Jun;51(6):1067. doi: 10.1038/s41588-019-0438-3.

PMID:
31110354
16.

The St. George's Respiratory Questionnaire Definition of Chronic Bronchitis May Be a Better Predictor of COPD Exacerbations Compared With the Classic Definition.

Kim V, Zhao H, Regan E, Han MK, Make BJ, Crapo JD, Jones PW, Curtis JL, Silverman EK, Criner GJ; COPDGene Investigators.

Chest. 2019 Oct;156(4):685-695. doi: 10.1016/j.chest.2019.03.041. Epub 2019 May 15.

PMID:
31047955
17.

Diffuse Idiopathic Skeletal Hyperostosis in Smokers and Restrictive Spirometry Pattern: An Analysis of the COPDGene Cohort.

Oudkerk SF, Mohamed Hoesein FAA, Öner FC, Verlaan JJ, de Jong PA, Kuperus JS, Cho M, McDonald ML, Lynch DA, Silverman EK, Crapo JD, Make BJ, Lowe KE, Regan EA.

J Rheumatol. 2019 May 1. pii: jrheum.181357. doi: 10.3899/jrheum.181357. [Epub ahead of print]

PMID:
31043539
18.

Resequencing Study Confirms That Host Defense and Cell Senescence Gene Variants Contribute to the Risk of Idiopathic Pulmonary Fibrosis.

Moore C, Blumhagen RZ, Yang IV, Walts A, Powers J, Walker T, Bishop M, Russell P, Vestal B, Cardwell J, Markin CR, Mathai SK, Schwarz MI, Steele MP, Lee J, Brown KK, Loyd JE, Crapo JD, Silverman EK, Cho MH, James JA, Guthridge JM, Cogan JD, Kropski JA, Swigris JJ, Bair C, Kim DS, Ji W, Kim H, Song JW, Maier LA, Pacheco KA, Hirani N, Poon AS, Li F, Jenkins RG, Braybrooke R, Saini G, Maher TM, Molyneaux PL, Saunders P, Zhang Y, Gibson KF, Kass DJ, Rojas M, Sembrat J, Wolters PJ, Collard HR, Sundy JS, O'Riordan T, Strek ME, Noth I, Ma SF, Porteous MK, Kreider ME, Patel NB, Inoue Y, Hirose M, Arai T, Akagawa S, Eickelberg O, Fernandez IE, Behr J, Mogulkoc N, Corte TJ, Glaspole I, Tomassetti S, Ravaglia C, Poletti V, Crestani B, Borie R, Kannengiesser C, Parfrey H, Fiddler C, Rassl D, Molina-Molina M, Machahua C, Worboys AM, Gudmundsson G, Isaksson HJ, Lederer DJ, Podolanczuk AJ, Montesi SB, Bendstrup E, Danchel V, Selman M, Pardo A, Henry MT, Keane MP, Doran P, Vašáková M, Sterclova M, Ryerson CJ, Wilcox PG, Okamoto T, Furusawa H, Miyazaki Y, Laurent G, Baltic S, Prele C, Moodley Y, Shea BS, Ohta K, Suzukawa M, Narumoto O, Nathan SD, Venuto DC, Woldehanna ML, Kokturk N, de Andrade JA, Luckhardt T, Kulkarni T, Bonella F, Donnelly SC, McElroy A, Armstong ME, Aranda A, Carbone RG, Puppo F, Beckman KB, Nickerson DA, Fingerlin TE, Schwartz DA.

Am J Respir Crit Care Med. 2019 Jul 15;200(2):199-208. doi: 10.1164/rccm.201810-1891OC.

19.

A genome-wide association study implicates NR2F2 in lymphangioleiomyomatosis pathogenesis.

Kim W, Giannikou K, Dreier JR, Lee S, Tyburczy ME, Silverman EK, Radzikowska E, Wu S, Wu CL, Henske EP, Hunninghake G, Carel H, Roman A, Pujana MA, Moss J, Won S, Kwiatkowski DJ.

Eur Respir J. 2019 Jun 27;53(6). pii: 1900329. doi: 10.1183/13993003.00329-2019. Print 2019 Jun.

PMID:
31000673
20.

Exploring the cross-phenotype network region of disease modules reveals concordant and discordant pathways between chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis.

Halu A, Liu S, Baek SH, Hobbs BD, Hunninghake GM, Cho MH, Silverman EK, Sharma A.

Hum Mol Genet. 2019 Jul 15;28(14):2352-2364. doi: 10.1093/hmg/ddz069.

PMID:
30997486
21.

RNA-sequencing across three matched tissues reveals shared and tissue-specific gene expression and pathway signatures of COPD.

Morrow JD, Chase RP, Parker MM, Glass K, Seo M, Divo M, Owen CA, Castaldi P, DeMeo DL, Silverman EK, Hersh CP.

Respir Res. 2019 Apr 2;20(1):65. doi: 10.1186/s12931-019-1032-z.

22.

Genetic Advances in Chronic Obstructive Pulmonary Disease. Insights from COPDGene.

Ragland MF, Benway CJ, Lutz SM, Bowler RP, Hecker J, Hokanson JE, Crapo JD, Castaldi PJ, DeMeo DL, Hersh CP, Hobbs BD, Lange C, Beaty TH, Cho MH, Silverman EK.

Am J Respir Crit Care Med. 2019 Sep 15;200(6):677-690. doi: 10.1164/rccm.201808-1455SO.

PMID:
30908940
23.

Reported environmental exposures are inversely associated with obtaining a genetic diagnosis in the Undiagnosed Diseases Network.

Silverman EK, Allard P, Loscalzo J, Mulvihill JJ, Korrick SA; Undiagnosed Diseases Network.

Am J Med Genet A. 2019 Jun;179(6):958-965. doi: 10.1002/ajmg.a.61132. Epub 2019 Mar 23.

PMID:
30903737
24.

Omics and the Search for Blood Biomarkers in Chronic Obstructive Pulmonary Disease. Insights from COPDGene.

Regan EA, Hersh CP, Castaldi PJ, DeMeo DL, Silverman EK, Crapo JD, Bowler RP.

Am J Respir Cell Mol Biol. 2019 Aug;61(2):143-149. doi: 10.1165/rcmb.2018-0245PS.

PMID:
30874442
25.

Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations.

Sakornsakolpat P, Prokopenko D, Lamontagne M, Reeve NF, Guyatt AL, Jackson VE, Shrine N, Qiao D, Bartz TM, Kim DK, Lee MK, Latourelle JC, Li X, Morrow JD, Obeidat M, Wyss AB, Bakke P, Barr RG, Beaty TH, Belinsky SA, Brusselle GG, Crapo JD, de Jong K, DeMeo DL, Fingerlin TE, Gharib SA, Gulsvik A, Hall IP, Hokanson JE, Kim WJ, Lomas DA, London SJ, Meyers DA, O'Connor GT, Rennard SI, Schwartz DA, Sliwinski P, Sparrow D, Strachan DP, Tal-Singer R, Tesfaigzi Y, Vestbo J, Vonk JM, Yim JJ, Zhou X, Bossé Y, Manichaikul A, Lahousse L, Silverman EK, Boezen HM, Wain LV, Tobin MD, Hobbs BD, Cho MH; SpiroMeta Consortium; International COPD Genetics Consortium.

Nat Genet. 2019 Mar;51(3):494-505. doi: 10.1038/s41588-018-0342-2. Epub 2019 Feb 25.

26.

New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.

Shrine N, Guyatt AL, Erzurumluoglu AM, Jackson VE, Hobbs BD, Melbourne CA, Batini C, Fawcett KA, Song K, Sakornsakolpat P, Li X, Boxall R, Reeve NF, Obeidat M, Zhao JH, Wielscher M, Weiss S, Kentistou KA, Cook JP, Sun BB, Zhou J, Hui J, Karrasch S, Imboden M, Harris SE, Marten J, Enroth S, Kerr SM, Surakka I, Vitart V, Lehtimäki T, Allen RJ, Bakke PS, Beaty TH, Bleecker ER, Bossé Y, Brandsma CA, Chen Z, Crapo JD, Danesh J, DeMeo DL, Dudbridge F, Ewert R, Gieger C, Gulsvik A, Hansell AL, Hao K, Hoffman JD, Hokanson JE, Homuth G, Joshi PK, Joubert P, Langenberg C, Li X, Li L, Lin K, Lind L, Locantore N, Luan J, Mahajan A, Maranville JC, Murray A, Nickle DC, Packer R, Parker MM, Paynton ML, Porteous DJ, Prokopenko D, Qiao D, Rawal R, Runz H, Sayers I, Sin DD, Smith BH, Soler Artigas M, Sparrow D, Tal-Singer R, Timmers PRHJ, Van den Berge M, Whittaker JC, Woodruff PG, Yerges-Armstrong LM, Troyanskaya OG, Raitakari OT, Kähönen M, Polašek O, Gyllensten U, Rudan I, Deary IJ, Probst-Hensch NM, Schulz H, James AL, Wilson JF, Stubbe B, Zeggini E, Jarvelin MR, Wareham N, Silverman EK, Hayward C, Morris AP, Butterworth AS, Scott RA, Walters RG, Meyers DA, Cho MH, Strachan DP, Hall IP, Tobin MD, Wain LV; Understanding Society Scientific Group.

Nat Genet. 2019 Mar;51(3):481-493. doi: 10.1038/s41588-018-0321-7. Epub 2019 Feb 25. Erratum in: Nat Genet. 2019 Jun;51(6):1067.

27.

Reply to Marruchella: Preserved Ratio Impaired Spirometry and Interstitial Lung Abnormalities in Smokers.

Wan ES, Silverman EK.

Am J Respir Crit Care Med. 2019 May 15;199(10):1293-1294. doi: 10.1164/rccm.201901-0018LE. No abstract available.

28.

Mortality and Exacerbations by Global Initiative for Chronic Obstructive Lung Disease Groups ABCD: 2011 Versus 2017 in the COPDGene® Cohort.

Criner RN, Labaki WW, Regan EA, Bon JM, Soler X, Bhatt SP, Murray S, Hokanson JE, Silverman EK, Crapo JD, Curtis JL, Martinez FJ, Make BJ, Han MK, Martinez CH; COPDGene® Investigators.

Chronic Obstr Pulm Dis. 2019 Jan 10;6(1):64-73. doi: 10.15326/jcopdf.6.1.2018.0130.

29.

Applying Functional Genomics to Chronic Obstructive Pulmonary Disease.

Silverman EK.

Ann Am Thorac Soc. 2018 Dec;15(Suppl 4):S239-S242. doi: 10.1513/AnnalsATS.201808-530MG.

PMID:
30759001
30.

Assessing pleiotropy and mediation in genetic loci associated with chronic obstructive pulmonary disease.

Parker MM, Lutz SM, Hobbs BD, Busch R, McDonald MN, Castaldi PJ, Beaty TH, Hokanson JE, Silverman EK, Cho MH.

Genet Epidemiol. 2019 Apr;43(3):318-329. doi: 10.1002/gepi.22192. Epub 2019 Feb 11.

PMID:
30740764
31.

Genome-Wide Association Analysis of Single-Breath DlCO.

Sakornsakolpat P, McCormack M, Bakke P, Gulsvik A, Make BJ, Crapo JD, Cho MH, Silverman EK.

Am J Respir Cell Mol Biol. 2019 May;60(5):523-531. doi: 10.1165/rcmb.2018-0384OC.

PMID:
30694715
32.

Efficient Variant Set Mixed Model Association Tests for Continuous and Binary Traits in Large-Scale Whole-Genome Sequencing Studies.

Chen H, Huffman JE, Brody JA, Wang C, Lee S, Li Z, Gogarten SM, Sofer T, Bielak LF, Bis JC, Blangero J, Bowler RP, Cade BE, Cho MH, Correa A, Curran JE, de Vries PS, Glahn DC, Guo X, Johnson AD, Kardia S, Kooperberg C, Lewis JP, Liu X, Mathias RA, Mitchell BD, O'Connell JR, Peyser PA, Post WS, Reiner AP, Rich SS, Rotter JI, Silverman EK, Smith JA, Vasan RS, Wilson JG, Yanek LR; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium; TOPMed Hematology and Hemostasis Working Group, Redline S, Smith NL, Boerwinkle E, Borecki IB, Cupples LA, Laurie CC, Morrison AC, Rice KM, Lin X.

Am J Hum Genet. 2019 Feb 7;104(2):260-274. doi: 10.1016/j.ajhg.2018.12.012. Epub 2019 Jan 10.

33.

Do sputum or circulating blood samples reflect the pulmonary transcriptomic differences of COPD patients? A multi-tissue transcriptomic network META-analysis.

Faner R, Morrow JD, Casas-Recasens S, Cloonan SM, Noell G, López-Giraldo A, Tal-Singer R, Miller BE, Silverman EK, Agustí A, Hersh CP.

Respir Res. 2019 Jan 8;20(1):5. doi: 10.1186/s12931-018-0965-y.

34.

Increased Airway Wall Thickness in Interstitial Lung Abnormalities and Idiopathic Pulmonary Fibrosis.

Miller ER, Putman RK, Diaz AA, Xu H, San José Estépar R, Araki T, Nishino M, Poli de Frías S, Hida T, Ross J, Coxson H, Dupuis J, O'Connor GT, Silverman EK, Rosas IO, Hatabu H, Washko G, Hunninghake GM.

Ann Am Thorac Soc. 2019 Apr;16(4):447-454. doi: 10.1513/AnnalsATS.201806-424OC.

PMID:
30543456
35.

Association Between Titin Loss-of-Function Variants and Early-Onset Atrial Fibrillation.

Choi SH, Weng LC, Roselli C, Lin H, Haggerty CM, Shoemaker MB, Barnard J, Arking DE, Chasman DI, Albert CM, Chaffin M, Tucker NR, Smith JD, Gupta N, Gabriel S, Margolin L, Shea MA, Shaffer CM, Yoneda ZT, Boerwinkle E, Smith NL, Silverman EK, Redline S, Vasan RS, Burchard EG, Gogarten SM, Laurie C, Blackwell TW, Abecasis G, Carey DJ, Fornwalt BK, Smelser DT, Baras A, Dewey FE, Jaquish CE, Papanicolaou GJ, Sotoodehnia N, Van Wagoner DR, Psaty BM, Kathiresan S, Darbar D, Alonso A, Heckbert SR, Chung MK, Roden DM, Benjamin EJ, Murray MF, Lunetta KL, Lubitz SA, Ellinor PT; DiscovEHR study and the NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium.

JAMA. 2018 Dec 11;320(22):2354-2364. doi: 10.1001/jama.2018.18179.

36.

Elevated circulating MMP-9 is linked to increased COPD exacerbation risk in SPIROMICS and COPDGene.

Wells JM, Parker MM, Oster RA, Bowler RP, Dransfield MT, Bhatt SP, Cho MH, Kim V, Curtis JL, Martinez FJ, Paine R 3rd, O'Neal W, Labaki WW, Kaner RJ, Barjaktarevic I, Han MK, Silverman EK, Crapo JD, Barr RG, Woodruff P, Castaldi PJ, Gaggar A, Investigators TSAC.

JCI Insight. 2018 Nov 15;3(22). pii: 123614. doi: 10.1172/jci.insight.123614.

37.

Childhood asthma is associated with COPD and known asthma variants in COPDGene: a genome-wide association study.

Hayden LP, Cho MH, Raby BA, Beaty TH, Silverman EK, Hersh CP; COPDGene Investigators.

Respir Res. 2018 Oct 29;19(1):209. doi: 10.1186/s12931-018-0890-0.

38.

Genomics and response to long-term oxygen therapy in chronic obstructive pulmonary disease.

Seo M, Qiu W, Bailey W, Criner GJ, Dransfield MT, Fuhlbrigge AL, Reilly JJ, Scholand MB, Castaldi P, Chase R, Parker M, Saferali A, Yun JH, Crapo JD, Cho MH, Beaty TH, Silverman EK, Hersh CP.

J Mol Med (Berl). 2018 Dec;96(12):1375-1385. doi: 10.1007/s00109-018-1708-8. Epub 2018 Oct 23.

PMID:
30353303
39.

Integrative Genomics Analysis Identifies ACVR1B as a Candidate Causal Gene of Emphysema Distribution.

Boueiz A, Pham B, Chase R, Lamb A, Lee S, Naing ZZC, Cho MH, Parker MM, Sakornsakolpat P, Hersh CP, Crapo JD, Stergachis AB, Tal-Singer R, DeMeo DL, Silverman EK, Zhou X, Castaldi PJ; COPDGene investigators, by Core Units:, ECLIPSE Investigators:, GenKOLS Investigators:.

Am J Respir Cell Mol Biol. 2019 Apr;60(4):388-398. doi: 10.1165/rcmb.2018-0110OC.

PMID:
30335480
40.

Imaging Advances in Chronic Obstructive Pulmonary Disease. Insights from the Genetic Epidemiology of Chronic Obstructive Pulmonary Disease (COPDGene) Study.

Bhatt SP, Washko GR, Hoffman EA, Newell JD Jr, Bodduluri S, Diaz AA, Galban CJ, Silverman EK, San José Estépar R, Lynch DA.

Am J Respir Crit Care Med. 2019 Feb 1;199(3):286-301. doi: 10.1164/rccm.201807-1351SO.

PMID:
30304637
41.

Integration of Molecular Interactome and Targeted Interaction Analysis to Identify a COPD Disease Network Module.

Sharma A, Kitsak M, Cho MH, Ameli A, Zhou X, Jiang Z, Crapo JD, Beaty TH, Menche J, Bakke PS, Santolini M, Silverman EK.

Sci Rep. 2018 Sep 27;8(1):14439. doi: 10.1038/s41598-018-32173-z.

42.

GWAS and systems biology analysis of depressive symptoms among smokers from the COPDGene cohort.

Heinzman JT, Hoth KF, Cho MH, Sakornsakolpat P, Regan EA, Make BJ, Kinney GL, Wamboldt FS, Holm KE, Bormann N, Robles J, Kim V, Iyer AS, Silverman EK, Crapo JD, Han S, Potash JB, Shinozaki G; COPDGene Investigators.

J Affect Disord. 2019 Jan 15;243:16-22. doi: 10.1016/j.jad.2018.09.003. Epub 2018 Sep 7.

PMID:
30219690
43.

Integrative epigenomic analysis in differentiated human primary bronchial epithelial cells exposed to cigarette smoke.

Glass K, Thibault D, Guo F, Mitchel JA, Pham B, Qiu W, Li Y, Jiang Z, Castaldi PJ, Silverman EK, Raby B, Park JA, Yuan GC, Zhou X.

Sci Rep. 2018 Aug 24;8(1):12750. doi: 10.1038/s41598-018-30781-3.

44.

Identification of Functional Variants in the FAM13A Chronic Obstructive Pulmonary Disease Genome-Wide Association Study Locus by Massively Parallel Reporter Assays.

Castaldi PJ, Guo F, Qiao D, Du F, Naing ZZC, Li Y, Pham B, Mikkelsen TS, Cho MH, Silverman EK, Zhou X.

Am J Respir Crit Care Med. 2019 Jan 1;199(1):52-61. doi: 10.1164/rccm.201802-0337OC.

PMID:
30079747
45.

Whole exome sequencing analysis in severe chronic obstructive pulmonary disease.

Qiao D, Ameli A, Prokopenko D, Chen H, Kho AT, Parker MM, Morrow J, Hobbs BD, Liu Y, Beaty TH, Crapo JD, Barnes KC, Nickerson DA, Bamshad M, Hersh CP, Lomas DA, Agusti A, Make BJ, Calverley PMA, Donner CF, Wouters EF, Vestbo J, Paré PD, Levy RD, Rennard SI, Tal-Singer R, Spitz MR, Sharma A, Ruczinski I, Lange C, Silverman EK, Cho MH.

Hum Mol Genet. 2018 Nov 1;27(21):3801-3812. doi: 10.1093/hmg/ddy269.

PMID:
30060175
46.

Distribution, temporal stability and association with all-cause mortality of the 2017 GOLD groups in the ECLIPSE cohort.

Faner R, Noell G, Badia JR, López-Giraldo A, Bakke P, Silverman EK, Tal-Singer R, Agustí A.

Respir Med. 2018 Aug;141:14-19. doi: 10.1016/j.rmed.2018.06.015. Epub 2018 Jun 19.

PMID:
30053959
47.

Rare Variants in Known Susceptibility Loci and Their Contribution to Risk of Lung Cancer.

Liu Y, Lusk CM, Cho MH, Silverman EK, Qiao D, Zhang R, Scheurer ME, Kheradmand F, Wheeler DA, Tsavachidis S, Armstrong G, Zhu D, Wistuba II, Chow CB, Behrens C, Pikielny CW, Neslund-Dudas C, Pinney SM, Anderson M, Kupert E, Bailey-Wilson J, Gaba C, Mandal D, You M, de Andrade M, Yang P, Field JK, Liloglou T, Davies M, Lissowska J, Swiatkowska B, Zaridze D, Mukeriya A, Janout V, Holcatova I, Mates D, Milosavljevic S, Scelo G, Brennan P, McKay J, Liu G, Hung RJ, Christiani DC, Schwartz AG, Amos CI, Spitz MR.

J Thorac Oncol. 2018 Oct;13(10):1483-1495. doi: 10.1016/j.jtho.2018.06.016. Epub 2018 Jul 4.

48.

Controllability in an islet specific regulatory network identifies the transcriptional factor NFATC4, which regulates Type 2 Diabetes associated genes.

Sharma A, Halu A, Decano JL, Padi M, Liu YY, Prasad RB, Fadista J, Santolini M, Menche J, Weiss ST, Vidal M, Silverman EK, Aikawa M, Barabási AL, Groop L, Loscalzo J.

NPJ Syst Biol Appl. 2018 Jul 3;4:25. doi: 10.1038/s41540-018-0057-0. eCollection 2018.

49.

Whole-Genome Sequencing in Severe Chronic Obstructive Pulmonary Disease.

Prokopenko D, Sakornsakolpat P, Fier HL, Qiao D, Parker MM, McDonald MN, Manichaikul A, Rich SS, Barr RG, Williams CJ, Brantly ML, Lange C, Beaty TH, Crapo JD, Silverman EK, Cho MH.

Am J Respir Cell Mol Biol. 2018 Nov;59(5):614-622. doi: 10.1165/rcmb.2018-0088OC.

PMID:
29949718
50.

Genome-wide assessment of gene-by-smoking interactions in COPD.

Park B, Koo SM, An J, Lee M, Kang HY, Qiao D, Cho MH, Sung J, Silverman EK, Yang HJ, Won S.

Sci Rep. 2018 Jun 18;8(1):9319. doi: 10.1038/s41598-018-27463-5.

Supplemental Content

Loading ...
Support Center