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Items: 26


ADAMDEC1 maintains a growth factor signaling loop in cancer stem cells.

Jimenez-Pascual A, Hale JS, Kordowski A, Pugh J, Silver DJ, Bayik D, Roversi G, Alban TJ, Rao S, Chen R, McIntyre TM, Colombo G, Taraboletti G, Holmberg KO, Forsberg-Nilsson K, Lathia JD, Siebzehnrubl FA.

Cancer Discov. 2019 Aug 21. pii: CD-18-1308. doi: 10.1158/2159-8290.CD-18-1308. [Epub ahead of print]


Development of a Cx46 Targeting Strategy for Cancer Stem Cells.

Mulkearns-Hubert EE, Torre-Healy LA, Silver DJ, Eurich JT, Bayik D, Serbinowski E, Hitomi M, Zhou J, Przychodzen B, Zhang R, Sprowls SA, Hale JS, Alban TJ, Berezovsky A, Bell BA, Lockman PR, Jha BK, Lathia JD.

Cell Rep. 2019 Apr 23;27(4):1062-1072.e5. doi: 10.1016/j.celrep.2019.03.079.


Therapeutic Injury and Tumor Regrowth: Tumor Resection and Radiation Establish the Recurrent Glioblastoma Microenvironment.

Silver DJ, Lathia JD.

EBioMedicine. 2018 May;31:13-14. doi: 10.1016/j.ebiom.2018.04.016. Epub 2018 Apr 20. No abstract available.


Revealing the glioma cancer stem cell interactome, one niche at a time.

Silver DJ, Lathia JD.

J Pathol. 2018 Mar;244(3):260-264. doi: 10.1002/path.5024. Epub 2018 Feb 2.


New Advances and Challenges of Targeting Cancer Stem Cells.

Dashzeveg NK, Taftaf R, Ramos EK, Torre-Healy L, Chumakova A, Silver DJ, Alban TJ, Sinyuk M, Thiagarajan PS, Jarrar AM, Turaga SM, Saygin C, Mulkearns-Hubert E, Hitomi M, Rich JN, Gerson SL, Lathia JD, Liu H.

Cancer Res. 2017 Oct 1;77(19):5222-5227. doi: 10.1158/0008-5472.CAN-17-0054. Epub 2017 Sep 19.


Glioblastoma Cancer Stem Cells Evade Innate Immune Suppression of Self-Renewal through Reduced TLR4 Expression.

Alvarado AG, Thiagarajan PS, Mulkearns-Hubert EE, Silver DJ, Hale JS, Alban TJ, Turaga SM, Jarrar A, Reizes O, Longworth MS, Vogelbaum MA, Lathia JD.

Cell Stem Cell. 2017 Apr 6;20(4):450-461.e4. doi: 10.1016/j.stem.2016.12.001. Epub 2017 Jan 12.


Functional Subclone Profiling for Prediction of Treatment-Induced Intratumor Population Shifts and Discovery of Rational Drug Combinations in Human Glioblastoma.

Reinartz R, Wang S, Kebir S, Silver DJ, Wieland A, Zheng T, Küpper M, Rauschenbach L, Fimmers R, Shepherd TM, Trageser D, Till A, Schäfer N, Glas M, Hillmer AM, Cichon S, Smith AA, Pietsch T, Liu Y, Reynolds BA, Yachnis A, Pincus DW, Simon M, Brüstle O, Steindler DA, Scheffler B.

Clin Cancer Res. 2017 Jan 15;23(2):562-574. doi: 10.1158/1078-0432.CCR-15-2089. Epub 2016 Aug 12.


Cancer Stem Cell-Secreted Macrophage Migration Inhibitory Factor Stimulates Myeloid Derived Suppressor Cell Function and Facilitates Glioblastoma Immune Evasion.

Otvos B, Silver DJ, Mulkearns-Hubert EE, Alvarado AG, Turaga SM, Sorensen MD, Rayman P, Flavahan WA, Hale JS, Stoltz K, Sinyuk M, Wu Q, Jarrar A, Kim SH, Fox PL, Nakano I, Rich JN, Ransohoff RM, Finke J, Kristensen BW, Vogelbaum MA, Lathia JD.

Stem Cells. 2016 Aug;34(8):2026-39. doi: 10.1002/stem.2393. Epub 2016 May 27.


Pharmacological Targeting of the Histone Chaperone Complex FACT Preferentially Eliminates Glioblastoma Stem Cells and Prolongs Survival in Preclinical Models.

Dermawan JK, Hitomi M, Silver DJ, Wu Q, Sandlesh P, Sloan AE, Purmal AA, Gurova KV, Rich JN, Lathia JD, Stark GR, Venere M.

Cancer Res. 2016 Apr 15;76(8):2432-42. doi: 10.1158/0008-5472.CAN-15-2162. Epub 2016 Feb 26.


Coordination of self-renewal in glioblastoma by integration of adhesion and microRNA signaling.

Alvarado AG, Turaga SM, Sathyan P, Mulkearns-Hubert EE, Otvos B, Silver DJ, Hale JS, Flavahan WA, Zinn PO, Sinyuk M, Li M, Guda MR, Velpula KK, Tsung AJ, Nakano I, Vogelbaum MA, Majumder S, Rich JN, Lathia JD.

Neuro Oncol. 2016 May;18(5):656-66. doi: 10.1093/neuonc/nov196. Epub 2015 Sep 15.


The intersection of cancer, cancer stem cells, and the immune system: therapeutic opportunities.

Silver DJ, Sinyuk M, Vogelbaum MA, Ahluwalia MS, Lathia JD.

Neuro Oncol. 2016 Feb;18(2):153-9. doi: 10.1093/neuonc/nov157. Epub 2015 Aug 11. Review.


Contributions of chondroitin sulfate proteoglycans to neurodevelopment, injury, and cancer.

Silver DJ, Silver J.

Curr Opin Neurobiol. 2014 Aug;27:171-8. doi: 10.1016/j.conb.2014.03.016. Epub 2014 Apr 22. Review.


Detection of primary cilia in human glioblastoma.

Sarkisian MR, Siebzehnrubl D, Hoang-Minh L, Deleyrolle L, Silver DJ, Siebzehnrubl FA, Guadiana SM, Srivinasan G, Semple-Rowland S, Harrison JK, Steindler DA, Reynolds BA.

J Neurooncol. 2014 Mar;117(1):15-24. doi: 10.1007/s11060-013-1340-y. Epub 2014 Feb 9.


Application of an RNA amplification method for reliable single-cell transcriptome analysis.

Suslov O, Silver DJ, Siebzehnrubl FA, Orjalo A, Ptitsyn A, Steindler DA.

Biotechniques. 2015 Sep 1;59(3):137-48. doi: 10.2144/000114331. eCollection 2015 Sep.


Chondroitin sulfate proteoglycans potently inhibit invasion and serve as a central organizer of the brain tumor microenvironment.

Silver DJ, Siebzehnrubl FA, Schildts MJ, Yachnis AT, Smith GM, Smith AA, Scheffler B, Reynolds BA, Silver J, Steindler DA.

J Neurosci. 2013 Sep 25;33(39):15603-17. doi: 10.1523/JNEUROSCI.3004-12.2013.


The ZEB1 pathway links glioblastoma initiation, invasion and chemoresistance.

Siebzehnrubl FA, Silver DJ, Tugertimur B, Deleyrolle LP, Siebzehnrubl D, Sarkisian MR, Devers KG, Yachnis AT, Kupper MD, Neal D, Nabilsi NH, Kladde MP, Suslov O, Brabletz S, Brabletz T, Reynolds BA, Steindler DA.

EMBO Mol Med. 2013 Aug;5(8):1196-212. doi: 10.1002/emmm.201302827. Epub 2013 Jul 1.


Overcoming macrophage-mediated axonal dieback following CNS injury.

Busch SA, Horn KP, Silver DJ, Silver J.

J Neurosci. 2009 Aug 12;29(32):9967-76. doi: 10.1523/JNEUROSCI.1151-09.2009.


Common astrocytic programs during brain development, injury and cancer.

Silver DJ, Steindler DA.

Trends Neurosci. 2009 Jun;32(6):303-11. doi: 10.1016/j.tins.2009.01.008. Epub 2009 May 3.


Astrocytic stem cells in the adult brain.

Laywell ED, Steindler DA, Silver DJ.

Neurosurg Clin N Am. 2007 Jan;18(1):21-30, viii. Review.


Chronic enhancement of the intrinsic growth capacity of sensory neurons combined with the degradation of inhibitory proteoglycans allows functional regeneration of sensory axons through the dorsal root entry zone in the mammalian spinal cord.

Steinmetz MP, Horn KP, Tom VJ, Miller JH, Busch SA, Nair D, Silver DJ, Silver J.

J Neurosci. 2005 Aug 31;25(35):8066-76. Erratum in: J Neurosci. 2005 Sep 14;25(37):8590-1.


Middle meningeal artery aneurysm associated with meningioma: case report.

O'Neill OR, Barnwell SL, Silver DJ.

Neurosurgery. 1995 Feb;36(2):396-8.


Spinal anesthesia for lumbar disc surgery: review of 576 operations.

Silver DJ, Dunsmore RH, Dickson CM.

Anesth Analg. 1976 Jul-Aug;55(4):550-4.


Measurement of regional cerebral blood flow. A comparison of the mass spectrographic and intra-arterial xenon 133 techniques.

Silver DJ, Roberts M, Owens G, Rembish R.

Neurology. 1974 Apr;24(4):322-4. No abstract available.


Acetic acid-soluble proteins in the developing sea urchin.

Silver DJ, Comb DG.

Dev Biol. 1967 Aug;16(2):107-17. No abstract available.


Synthesis of basic proteins and cellular RNA species during sea urchin development.

Comb DC, Silver DJ.

Natl Cancer Inst Monogr. 1966 Dec;23:325-36. No abstract available.


Free amino acid pools in the developing sea urchin Lytechinus variegatus.

Silver DJ, Comb DG.

Exp Cell Res. 1966 Oct;43(3):699-700. No abstract available.


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