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Semi-synthesis of β-keto-1,2,3-triazole derivatives from ethinylestradiol and evaluation of the cytotoxic activity.

Queiroz TM, Orozco EVM, Silva VR, Santos LS, Soares MBP, Bezerra DP, Porto ALM.

Heliyon. 2019 Sep 6;5(9):e02408. doi: 10.1016/j.heliyon.2019.e02408. eCollection 2019 Sep.


Thimet Oligopeptidase (EC Key Functions Suggested by Knockout Mice Phenotype Characterization.

Santos NBD, Franco RD, Camarini R, Munhoz CD, Eichler RAS, Gewehr MCF, Reckziegel P, Llanos RP, Dale CS, Silva VROD, Borges VF, Lima BHF, Cunha FQ, Visniauskas B, Chagas JR, Tufik S, Peres FF, Abilio VC, Florio JC, Iwai LK, Rioli V, Presoto BC, Guimaraes AO, Pesquero JB, Bader M, Castro LM, Ferro ES.

Biomolecules. 2019 Aug 19;9(8). pii: E382. doi: 10.3390/biom9080382.


Structure-Based Molecular Networking for the Target Discovery of Oxahomoaporphine and 8-Oxohomoaporphine Alkaloids from Duguetia surinamensis.

Paz WHP, de Oliveira RN, Heerdt G, Angolini CFF, S de Medeiros L, Silva VR, Santos LS, Soares MBP, Bezerra DP, Morgon NH, Almeida JRGS, da Silva FMA, Costa EV, Koolen HHF.

J Nat Prod. 2019 Aug 23;82(8):2220-2228. doi: 10.1021/acs.jnatprod.9b00287. Epub 2019 Aug 12.


Segmental and extrasegmental hypoalgesic effects of low-frequency pulsed current and modulated kilohertz-frequency currents in healthy subjects: randomized clinical trial.

Rampazo da Silva ÉP, Silva VRD, Bernardes AS, Matuzawa F, Liebano RE.

Physiother Theory Pract. 2019 Aug 12:1-10. doi: 10.1080/09593985.2019.1650857. [Epub ahead of print]


Pharmacological and physicochemical profile of arylacetamides as tools against human cancers.

Ferreira PMP, Machado KDC, Lavorato SN, Oliveira FCE, Silva JDN, Almeida AAC, Santos LS, Silva VR, Bezerra DP, Soares MBP, Pessoa C, Moraes Filho MO, Ferreira JRO, Sousa JMCE, Maltarollo VG, Alves RJ.

Toxicol Appl Pharmacol. 2019 Oct 1;380:114692. doi: 10.1016/j.taap.2019.114692. Epub 2019 Jul 26.


Effects of red and near-infrared LED light therapy on full-thickness skin graft in rats.

Martignago CCS, Tim CR, Assis L, Da Silva VR, Santos ECBD, Vieira FN, Parizotto NA, Liebano RE.

Lasers Med Sci. 2019 Jun 5. doi: 10.1007/s10103-019-02812-6. [Epub ahead of print]


TGF-β1 downregulation in the hypothalamus of obese mice through acute exercise.

Silva VRR, Lenhare L, Katashima CK, Morari J, M-Assis A, Gaspar RS, da Silva ASR, Moura LP, Pauli JR, Cintra DE, Velloso LA, Ropelle ER.

J Cell Biochem. 2019 Oct;120(10):18186-18192. doi: 10.1002/jcb.29124. Epub 2019 May 29.


Persistence and clinical relevance of Zika virus in the male genital tract.

Kurscheidt FA, Mesquita CSS, Damke GMZF, Damke E, Carvalho ARBA, Suehiro TT, Teixeira JJV, da Silva VRS, Souza RP, Consolaro MEL.

Nat Rev Urol. 2019 Apr;16(4):211-230. doi: 10.1038/s41585-019-0149-7. Review.


Effect of Er,Cr:YSGG laser associated with fluoride on the control of enamel erosion progression.

da Silva VRM, Viana ÍEL, Lopes RM, Zezell DM, Scaramucci T, Aranha ACC.

Arch Oral Biol. 2019 Mar;99:156-160. doi: 10.1016/j.archoralbio.2019.01.011. Epub 2019 Jan 17.


Toll-Like Receptor 3-TRIF Pathway Activation by Neospora caninum RNA Enhances Infection Control in Mice.

Miranda VDS, França FBF, da Costa MS, Silva VRS, Mota CM, Barros PDSC, Parreira KS, Santiago FM, Mineo JR, Mineo TWP.

Infect Immun. 2019 Mar 25;87(4). pii: e00739-18. doi: 10.1128/IAI.00739-18. Print 2019 Apr.


Participation in Cervical Screening by Self-collection, Pap, or a Choice of Either in Brazil.

Castle PE, Silva VRS, Consolaro MEL, Kienen N, Bittencourt L, Pelloso SM, Partridge EE, Pierz A, Dartibale CB, Uchimura NS, Scarinci IC.

Cancer Prev Res (Phila). 2019 Mar;12(3):159-170. doi: 10.1158/1940-6207.CAPR-18-0419. Epub 2019 Jan 16.


The role of sphingosine-1-phosphate in skeletal muscle: Physiology, mechanisms, and clinical perspectives.

Cordeiro AV, Silva VRR, Pauli JR, da Silva ASR, Cintra DE, Moura LP, Ropelle ER.

J Cell Physiol. 2019 Jul;234(7):10047-10059. doi: 10.1002/jcp.27870. Epub 2018 Dec 6. Review.


Antitumor Effect of the Essential Oil from the Leaves of Croton matourensis Aubl. (Euphorbiaceae).

Lima EJSP, Alves RG, D Elia GMA, Anunciação TAD, Silva VR, Santos LS, Soares MBP, Cardozo NMD, Costa EV, Silva FMAD, Koolen HHF, Bezerra DP.

Molecules. 2018 Nov 14;23(11). pii: E2974. doi: 10.3390/molecules23112974.


Case Reports: Prolonged Detection of Zika Virus RNA in Vaginal and Endocervical Samples from a Brazilian Woman, 2018.

da Cruz TE, Souza RP, Pelloso SM, Morelli F, Suehiro TT, Damke E, Bonfim-Mendonça PS, da Silva VRS, Consolaro MEL.

Am J Trop Med Hyg. 2019 Jan;100(1):183-186. doi: 10.4269/ajtmh.18-0623.


Nicotinamide riboside induces a thermogenic response in lean mice.

Crisol BM, Veiga CB, Lenhare L, Braga RR, Silva VRR, da Silva ASR, Cintra DE, Moura LP, Pauli JR, Ropelle ER.

Life Sci. 2018 Oct 15;211:1-7. doi: 10.1016/j.lfs.2018.09.015. Epub 2018 Sep 6.


The role of cathepsin B in autophagy during obesity: A systematic review.

Araujo TF, Cordeiro AV, Vasconcelos DAA, Vitzel KF, Silva VRR.

Life Sci. 2018 Sep 15;209:274-281. doi: 10.1016/j.lfs.2018.08.024. Epub 2018 Aug 11. Review.


Exercise activates the hypothalamic S1PR1-STAT3 axis through the central action of interleukin 6 in mice.

Silva VRR, Micheletti TO, Katashima CK, Lenhare L, Morari J, Moura-Assis A, de Lima-Júnior JC, Camargo JA, Passos GR, Gaspar RS, Velloso LA, Saad MJ, da Silva ASR, Moura LP, Cintra DE, Pauli JR, Ropelle ER.

J Cell Physiol. 2018 Dec;233(12):9426-9436. doi: 10.1002/jcp.26818. Epub 2018 Jul 31.


A Comparison of Three Methods for the Analysis of Skin Flap Viability: Reliability and Validity.

Tim CR, Martignago CCS, da Silva VR, Dos Santos ECB, Vieira FN, Parizotto NA, Liebano RE.

Adv Wound Care (New Rochelle). 2018 May 1;7(5):157-163. doi: 10.1089/wound.2017.0758.


Effect of the Auricular Acupoint Associated with Physical Exercise in Elderly People: A Randomized Clinical Test.

de Carvalho Fonseca RG, Silva AM, Teixeira LF, Silva VR, Dos Reis LM, Silva Santos AT.

J Acupunct Meridian Stud. 2018 Aug;11(4):137-144. doi: 10.1016/j.jams.2018.05.003. Epub 2018 May 16.


Effects of ninety minutes per week of continuous aerobic exercise on blood pressure in hypertensive obese humans.

Belozo FL, Katashima CK, Cordeiro AV, Lenhare L, Alves JF, Silva VRR.

J Exerc Rehabil. 2018 Feb 26;14(1):126-132. doi: 10.12965/jer.1835162.581. eCollection 2018 Feb.


Study protocol of hypoalgesic effects of low frequency and burst-modulated alternating currents on healthy individuals.

Rampazo da Silva ÉP, da Silva VR, Bernardes AS, Matuzawa FM, Liebano RE.

Pain Manag. 2018 Mar;8(2):71-77. doi: 10.2217/pmt-2017-0058. Epub 2018 Feb 16.


Xylopine Induces Oxidative Stress and Causes G2/M Phase Arrest, Triggering Caspase-Mediated Apoptosis by p53-Independent Pathway in HCT116 Cells.

Santos LS, Silva VR, Menezes LRA, Soares MBP, Costa EV, Bezerra DP.

Oxid Med Cell Longev. 2017;2017:7126872. doi: 10.1155/2017/7126872. Epub 2017 Dec 6.


A ruthenium-based 5-fluorouracil complex with enhanced cytotoxicity and apoptosis induction action in HCT116 cells.

Silva VR, Corrêa RS, Santos LS, Soares MBP, Batista AA, Bezerra DP.

Sci Rep. 2018 Jan 10;8(1):288. doi: 10.1038/s41598-017-18639-6.


β-hydroxy-β-methylbutyrate free acid supplementation may improve recovery and muscle adaptations after resistance training: a systematic review.

Silva VR, Belozo FL, Micheletti TO, Conrado M, Stout JR, Pimentel GD, Gonzalez AM.

Nutr Res. 2017 Sep;45:1-9. doi: 10.1016/j.nutres.2017.07.008. Epub 2017 Jul 26. Review.


Job satisfaction in an oncology nursing team.

Silva VRD, Velasque LS, Tonini T.

Rev Bras Enferm. 2017 Sep-Oct;70(5):988-995. doi: 10.1590/0034-7167-2016-0422. English, Portuguese.


Chronic exercise reduces hypothalamic transforming growth factor-β1 in middle-aged obese mice.

Silva VRR, Katashima CK, Lenhare L, Silva CGB, Morari J, Camargo RL, Velloso LA, Saad MA, da Silva ASR, Pauli JR, Ropelle ER.

Aging (Albany NY). 2017 Aug 28;9(8):1926-1940. doi: 10.18632/aging.101281.


iNOS promotes hypothalamic insulin resistance associated with deregulation of energy balance and obesity in rodents.

Katashima CK, Silva VRR, Lenhare L, Marin RM, Carvalheira JBC.

Sci Rep. 2017 Aug 23;7(1):9265. doi: 10.1038/s41598-017-08920-z.


Physical exercise increases Sestrin 2 protein levels and induces autophagy in the skeletal muscle of old mice.

Lenhare L, Crisol BM, Silva VRR, Katashima CK, Cordeiro AV, Pereira KD, Luchessi AD, da Silva ASR, Cintra DE, Moura LP, Pauli JR, Ropelle ER.

Exp Gerontol. 2017 Oct 15;97:17-21. doi: 10.1016/j.exger.2017.07.009. Epub 2017 Jul 17.


Acute liver failure is associated with altered cerebral expression profiles of long non-coding RNAs.

Silva VR, Secolin R, Vemuganti R, Lopes-Cendes I, Hazell AS.

Neurosci Lett. 2017 Aug 24;656:58-64. doi: 10.1016/j.neulet.2017.06.038. Epub 2017 Jun 23.


Ursolic acid and mechanisms of actions on adipose and muscle tissue: a systematic review.

Katashima CK, Silva VR, Gomes TL, Pichard C, Pimentel GD.

Obes Rev. 2017 Jun;18(6):700-711. doi: 10.1111/obr.12523. Epub 2017 Mar 23. Review.


Applications of deuterium oxide in human health.

Bila WC, Mariano RMDS, Silva VR, Dos Santos MESM, Lamounier JA, Ferriolli E, Galdino AS.

Isotopes Environ Health Stud. 2017 Aug;53(4):327-343. doi: 10.1080/10256016.2017.1281806. Epub 2017 Feb 6. Review.


Hypothalamic S1P/S1PR1 axis controls energy homeostasis in Middle-Aged Rodents: the reversal effects of physical exercise.

Silva VR, Katashima CK, Bueno Silva CG, Lenhare L, Micheletti TO, Camargo RL, Ghezzi AC, Camargo JA, Assis AM, Tobar N, Morari J, Razolli DS, Moura LP, Pauli JR, Cintra DE, Velloso LA, Saad MJ, Ropelle ER.

Aging (Albany NY). 2016 Dec 26;9(1):142-155. doi: 10.18632/aging.101138.


Correlation of phenotypic tests with the presence of the blaZ gene for detection of beta-lactamase.

Ferreira AM, Martins KB, Silva VR, Mondelli AL, Cunha ML.

Braz J Microbiol. 2017 Jan - Mar;48(1):159-166. doi: 10.1016/j.bjm.2016.10.011. Epub 2016 Nov 11.


Polyurethane foam impregnated with lignin as a filler for the removal of crude oil from contaminated water.

Santos OS, Coelho da Silva M, Silva VR, Mussel WN, Yoshida MI.

J Hazard Mater. 2017 Feb 15;324(Pt B):406-413. doi: 10.1016/j.jhazmat.2016.11.004. Epub 2016 Nov 3.


Training through gametherapy promotes coactivation of the pelvic floor and abdominal muscles in young women, nulliparous and continents.

Silva VR, Riccetto CL, Martinho NM, Marques J, Carvalho LC, Botelho S.

Int Braz J Urol. 2016 Jul-Aug;42(4):779-86. doi: 10.1590/S1677-5538.IBJU.2014.0580.


The effects of training by virtual reality or gym ball on pelvic floor muscle strength in postmenopausal women: a randomized controlled trial.

Martinho NM, Silva VR, Marques J, Carvalho LC, Iunes DH, Botelho S.

Braz J Phys Ther. 2016 Mar 22;20(3):248-57. doi: 10.1590/bjpt-rbf.2014.0148.


Aldosterone is associated with left ventricular hypertrophy in hemodialysis patients.

Feniman De Stefano GM, Zanati-Basan SG, De Stefano LM, Silva VR, Xavier PS, Barretti P, da Silva Franco RJ, Caramori JC, Martin LC.

Ther Adv Cardiovasc Dis. 2016 Oct;10(5):304-13. doi: 10.1177/1753944716644583. Epub 2016 Apr 27. Review.


HPV Infection and Cervical Abnormalities in HIV Positive Women in Different Regions of Brazil, a Middle-Income Country.

Freitas BC, Suehiro TT, Consolaro ME, Silva VR.

Asian Pac J Cancer Prev. 2015;16(18):8085-91. Review.


Simultaneous detection of human papillomavirus integration and c-MYC gene amplification in cervical lesions: an emerging marker for the risk to progression.

Gimenes F, Souza RP, de Abreu AL, Pereira MW, Consolaro ME, da Silva VR.

Arch Gynecol Obstet. 2016 Apr;293(4):857-63. doi: 10.1007/s00404-015-3870-3. Epub 2015 Aug 28.


Abdominopelvic kinesiotherapy for pelvic floor muscle training: a tested proposal in different groups.

Botelho S, Martinho NM, Silva VR, Marques J, Alves FK, Riccetto C.

Int Urogynecol J. 2015 Dec;26(12):1867-9. doi: 10.1007/s00192-015-2699-4. Epub 2015 May 21.


Intra and inter-rater reliability study of pelvic floor muscle dynamometric measurements.

Martinho NM, Marques J, Silva VR, Silva SL, Carvalho LC, Botelho S.

Braz J Phys Ther. 2015 Mar-Apr;19(2):97-104. doi: 10.1590/bjpt-rbf.2014.0083. Epub 2015 Apr 27.


Virtual reality: a proposal for pelvic floor muscle training.

Botelho S, Martinho NM, Silva VR, Marques J, Carvalho LC, Riccetto C.

Int Urogynecol J. 2015 Nov;26(11):1709-12. doi: 10.1007/s00192-015-2698-5. Epub 2015 Apr 30.


Anthropometric and biochemical profile of children and adolescents with chronic kidney disease in a predialysis pediatric interdisciplinary program.

Silva VR, Soares CB, Magalhães JO, de Barcelos IP, Cerqueira DC, Simões e Silva AC, Oliveira EA.

ScientificWorldJournal. 2015;2015:810758. doi: 10.1155/2015/810758. Epub 2015 Jan 13.


Erratum to: Acute liver failure-induced hepatic encephalopathy is associated with changes in microRNA expression profiles in cerebral cortex of the mouse.

Vemuganti R, Silva VR, Mehta SL, Hazell AS.

Metab Brain Dis. 2015 Feb;30(1):247. doi: 10.1007/s11011-014-9644-y. No abstract available.


[Evaluation of coronary risk and its relationship to health actions in hypertensive patients].

Silva VR, Molina Mdel C, Cade NV.

Rev Bras Enferm. 2014 Sep-Oct;67(5):730-6. doi: 10.1590/0034-7167.2014670509. Portuguese.


Human leukocyte antigen (HLA)-G and cervical cancer immunoediting: a candidate molecule for therapeutic intervention and prognostic biomarker?

Gimenes F, Teixeira JJ, de Abreu AL, Souza RP, Pereira MW, da Silva VR, Bôer CG, Maria-Engler SS, Bonini MG, Borelli SD, Consolaro ME.

Biochim Biophys Acta. 2014 Dec;1846(2):576-89. doi: 10.1016/j.bbcan.2014.10.004. Epub 2014 Oct 23. Review.


Investigation of polymorphisms in pre-eclampsia related genes VEGF and IL1A.

Silva VR, Soardi FC, Tanaka SC, da Silva-Grecco RL, Paschoini MC, Balarin MA.

Arch Gynecol Obstet. 2015 May;291(5):1029-35. doi: 10.1007/s00404-014-3503-2. Epub 2014 Oct 17.


Hypothalamic S1P/S1PR1 axis controls energy homeostasis.

Silva VR, Micheletti TO, Pimentel GD, Katashima CK, Lenhare L, Morari J, Mendes MC, Razolli DS, Rocha GZ, de Souza CT, Ryu D, Prada PO, Velloso LA, Carvalheira JB, Pauli JR, Cintra DE, Ropelle ER.

Nat Commun. 2014 Sep 25;5:4859. doi: 10.1038/ncomms5859.


Spinosad and the tomato borer Tuta absoluta: a bioinsecticide, an invasive pest threat, and high insecticide resistance.

Campos MR, Rodrigues AR, Silva WM, Silva TB, Silva VR, Guedes RN, Siqueira HA.

PLoS One. 2014 Aug 14;9(8):e103235. doi: 10.1371/journal.pone.0103235. eCollection 2014.


Acute liver failure-induced hepatic encephalopathy s associated with changes in microRNA expression rofiles in cerebral cortex of the mouse [corrected].

Vemuganti R, Silva VR, Mehta SL, Hazell AS.

Metab Brain Dis. 2014 Dec;29(4):891-9. doi: 10.1007/s11011-014-9545-0. Epub 2014 May 27. Erratum in: Metab Brain Dis. 2015 Feb;30(1):247.


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