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Items: 10

1.

DnaQ exonuclease-like domain of Cas2 promotes spacer integration in a type I-E CRISPR-Cas system.

Drabavicius G, Sinkunas T, Silanskas A, Gasiunas G, Venclovas Č, Siksnys V.

EMBO Rep. 2018 Jul;19(7). pii: e45543. doi: 10.15252/embr.201745543. Epub 2018 Jun 11.

PMID:
29891635
2.

The H-subunit of the restriction endonuclease CglI contains a prototype DEAD-Z1 helicase-like motor.

Toliusis P, Tamulaitiene G, Grigaitis R, Tuminauskaite D, Silanskas A, Manakova E, Venclovas C, Szczelkun MD, Siksnys V, Zaremba M.

Nucleic Acids Res. 2018 Mar 16;46(5):2560-2572. doi: 10.1093/nar/gky107.

3.

CgII cleaves DNA using a mechanism distinct from other ATP-dependent restriction endonucleases.

Toliusis P, Zaremba M, Silanskas A, Szczelkun MD, Siksnys V.

Nucleic Acids Res. 2017 Aug 21;45(14):8435-8447. doi: 10.1093/nar/gkx580.

4.

Rapid characterization of CRISPR-Cas9 protospacer adjacent motif sequence elements.

Karvelis T, Gasiunas G, Young J, Bigelyte G, Silanskas A, Cigan M, Siksnys V.

Genome Biol. 2015 Nov 19;16:253. doi: 10.1186/s13059-015-0818-7.

5.

DNA cleavage by CgII and NgoAVII requires interaction between N- and R-proteins and extensive nucleotide hydrolysis.

Zaremba M, Toliusis P, Grigaitis R, Manakova E, Silanskas A, Tamulaitiene G, Szczelkun MD, Siksnys V, Tamulaitiene G, Silanskas A, Grazulis S, Zaremba M, Siksnys V.

Nucleic Acids Res. 2015 Mar 31;43(6):3405. doi: 10.1093/nar/gkv049. Epub 2015 Mar 13. No abstract available.

6.

Crystal structure of the R-protein of the multisubunit ATP-dependent restriction endonuclease NgoAVII.

Tamulaitiene G, Silanskas A, Grazulis S, Zaremba M, Siksnys V.

Nucleic Acids Res. 2014 Dec 16;42(22):14022-30. doi: 10.1093/nar/gku1237. Epub 2014 Nov 27.

7.

DNA cleavage by CgII and NgoAVII requires interaction between N- and R-proteins and extensive nucleotide hydrolysis.

Zaremba M, Toliusis P, Grigaitis R, Manakova E, Silanskas A, Tamulaitiene G, Szczelkun MD, Siksnys V.

Nucleic Acids Res. 2014 Dec 16;42(22):13887-96. doi: 10.1093/nar/gku1236. Epub 2014 Nov 27. Erratum in: Nucleic Acids Res. 2015 Mar 31;43(6):3405.

8.

Catalytic activity control of restriction endonuclease--triplex forming oligonucleotide conjugates.

Silanskas A, Zaremba M, Sasnauskas G, Siksnys V.

Bioconjug Chem. 2012 Feb 15;23(2):203-11. doi: 10.1021/bc200480m. Epub 2012 Jan 30.

PMID:
22236287
9.

Photocaged variants of the MunI and PvuII restriction enzymes.

Silanskas A, Foss M, Wende W, Urbanke C, Lagunavicius A, Pingoud A, Siksnys V.

Biochemistry. 2011 Apr 12;50(14):2800-7. doi: 10.1021/bi2000609. Epub 2011 Mar 16.

PMID:
21410225
10.

Endonucleases induced TRAIL-insensitive apoptosis in ovarian carcinoma cells.

Geel TM, Meiss G, van der Gun BT, Kroesen BJ, de Leij LF, Zaremba M, Silanskas A, Kokkinidis M, Pingoud A, Ruiters MH, McLaughlin PM, Rots MG.

Exp Cell Res. 2009 Sep 10;315(15):2487-95. doi: 10.1016/j.yexcr.2009.06.011. Epub 2009 Jun 18.

PMID:
19540229

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