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Items: 9


Metformin strongly affects transcriptome of peripheral blood cells in healthy individuals.

Ustinova M, Silamikelis I, Kalnina I, Ansone L, Rovite V, Elbere I, Radovica-Spalvina I, Fridmanis D, Aladyeva J, Konrade I, Pirags V, Klovins J.

PLoS One. 2019 Nov 8;14(11):e0224835. doi: 10.1371/journal.pone.0224835. eCollection 2019.


Control of Acinetobacter baumannii outbreak in the neonatal intensive care unit in Latvia: whole-genome sequencing powered investigation and closure of the ward.

Gramatniece A, Silamikelis I, Zahare I, Urtans V, Zahare I, Dimina E, Saule M, Balode A, Radovica-Spalvina I, Klovins J, Fridmanis D, Dumpis U.

Antimicrob Resist Infect Control. 2019 May 22;8:84. doi: 10.1186/s13756-019-0537-z. eCollection 2019.


Significantly altered peripheral blood cell DNA methylation profile as a result of immediate effect of metformin use in healthy individuals.

Elbere I, Silamikelis I, Ustinova M, Kalnina I, Zaharenko L, Peculis R, Konrade I, Ciuculete DM, Zhukovsky C, Gudra D, Radovica-Spalvina I, Fridmanis D, Pirags V, Schiöth HB, Klovins J.

Clin Epigenetics. 2018 Dec 13;10(1):156. doi: 10.1186/s13148-018-0593-x.


Association of metformin administration with gut microbiome dysbiosis in healthy volunteers.

Elbere I, Kalnina I, Silamikelis I, Konrade I, Zaharenko L, Sekace K, Radovica-Spalvina I, Fridmanis D, Gudra D, Pirags V, Klovins J.

PLoS One. 2018 Sep 27;13(9):e0204317. doi: 10.1371/journal.pone.0204317. eCollection 2018.


A widely used sampling device in colorectal cancer screening programmes allows for large-scale microbiome studies.

Gudra D, Shoaie S, Fridmanis D, Klovins J, Wefer H, Silamikelis I, Peculis R, Kalnina I, Elbere I, Radovica-Spalvina I, Hultcrantz R, Šķenders Ģ, Leja M, Engstrand L.

Gut. 2019 Sep;68(9):1723-1725. doi: 10.1136/gutjnl-2018-316225. Epub 2018 Sep 21. No abstract available.


Gene expression profiling of fast- and slow-growing non-functioning gonadotroph pituitary adenomas.

Falch CM, Sundaram AYM, Øystese KA, Normann KR, Lekva T, Silamikelis I, Eieland AK, Andersen M, Bollerslev J, Olarescu NC.

Eur J Endocrinol. 2018 Mar;178(3):295-307. doi: 10.1530/EJE-17-0702. Epub 2017 Dec 19.


MIRU-VNTR genotype diversity and indications of homoplasy in M. avium strains isolated from humans and slaughter pigs in Latvia.

Kalvisa A, Tsirogiannis C, Silamikelis I, Skenders G, Broka L, Zirnitis A, Jansone I, Ranka R.

Infect Genet Evol. 2016 Sep;43:15-21. doi: 10.1016/j.meegid.2016.05.013. Epub 2016 May 11.


Next-generation-sequencing-based identification of familial hypercholesterolemia-related mutations in subjects with increased LDL-C levels in a latvian population.

Radovica-Spalvina I, Latkovskis G, Silamikelis I, Fridmanis D, Elbere I, Ventins K, Ozola G, Erglis A, Klovins J.

BMC Med Genet. 2015 Sep 28;16:86. doi: 10.1186/s12881-015-0230-x.


Association between CETP, MLXIPL, and TOMM40 polymorphisms and serum lipid levels in a Latvian population.

Radovica I, Fridmanis D, Silamikelis I, Nikitina-Zake L, Klovins J.

Meta Gene. 2014 Aug 20;2:565-78. doi: 10.1016/j.mgene.2014.07.006. eCollection 2014 Dec.

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