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Items: 1 to 50 of 105

1.

CD8 infiltration is associated with disease control and tobacco exposure in intermediate-risk oropharyngeal cancer.

Kemnade JO, Elhalawani H, Castro P, Yu J, Lai S, Ittmann M, Mohamed ASR, Lai SY, Fuller CD, Sikora AG, Sandulache VC.

Sci Rep. 2020 Jan 14;10(1):243. doi: 10.1038/s41598-019-57111-5.

2.

Leveraging the Versatility of the Chicken Embryo Chorioallantoic Membrane (CAM) Model as a Tool in the Fight Against Cancer.

Villanueva H, Villanueva M, Francisco S, Liu HC, Sikora AG.

J Biomol Tech. 2019 Dec;30(Suppl):S25.

3.

A Hidden Epidemic of "Intermediate Risk" Oropharynx Cancer.

Sandulache VC, Wilde DC, Sturgis EM, Chiao EY, Sikora AG.

Laryngoscope Investig Otolaryngol. 2019 Oct 17;4(6):617-623. doi: 10.1002/lio2.316. eCollection 2019 Dec. Review.

4.

Comparative Treatment Outcomes for Patients With Idiopathic Subglottic Stenosis.

Gelbard A, Anderson C, Berry LD, Amin MR, Benninger MS, Blumin JH, Bock JM, Bryson PC, Castellanos PF, Chen SC, Clary MS, Cohen SM, Crawley BK, Dailey SH, Daniero JJ, de Alarcon A, Donovan DT, Edell ES, Ekbom DC, Fernandes-Taylor S, Fink DS, Franco RA, Garrett CG, Guardiani EA, Hillel AT, Hoffman HT, Hogikyan ND, Howell RJ, Huang LC, Hussain LK, Johns MM 3rd, Kasperbauer JL, Khosla SM, Kinnard C, Kupfer RA, Langerman AJ, Lentz RJ, Lorenz RR, Lott DG, Lowery AS, Makani SS, Maldonado F, Mannion K, Matrka L, McWhorter AJ, Merati AL, Mori MC, Netterville JL, O'Dell K, Ongkasuwan J, Postma GN, Reder LS, Rohde SL, Richardson BE, Rickman OB, Rosen CA, Rutter MJ, Sandhu GS, Schindler JS, Schneider GT, Shah RN, Sikora AG, Sinard RJ, Smith ME, Smith LJ, Soliman AMS, Sveinsdóttir S, Van Daele DJ, Veivers D, Verma SP, Weinberger PM, Weissbrod PA, Wootten CT, Shyr Y, Francis DO.

JAMA Otolaryngol Head Neck Surg. 2019 Oct 31:1-10. doi: 10.1001/jamaoto.2019.3022. [Epub ahead of print]

5.

Innovations in risk-stratification and treatment of Veterans with oropharynx cancer; roadmap of the 2019 Field Based Meeting.

Sandulache VC, Lei YL, Heasley LE, Chang M, Amos CI, Sturgis EM, Graboyes E, Chiao EY, Rogus-Pulia N, Lewis J, Madabhushi A, Frederick MJ, Sabichi A, Ittmann M, Yarbrough WG, Chung CH, Ferrarotto R, Mai W, Skinner HD, Duvvuri U, Gerngross P, Sikora AG.

Oral Oncol. 2019 Oct 21:104440. doi: 10.1016/j.oraloncology.2019.104440. [Epub ahead of print] No abstract available.

PMID:
31648864
6.

Topical Esomeprazole Mitigates Radiation-Induced Dermal Inflammation and Fibrosis.

Pham N, Ludwig MS, Wang M, Ebrahimpour A, Bonnen MD, Diwan AH, Kim SJ, Bryan J, Newton JM, Sikora AG, Donovan DT, Sandulache V, Ghebre YT.

Radiat Res. 2019 Nov;192(5):473-482. doi: 10.1667/RR15398.1. Epub 2019 Aug 15.

PMID:
31415221
7.

Immune microenvironment modulation unmasks therapeutic benefit of radiotherapy and checkpoint inhibition.

Newton JM, Hanoteau A, Liu HC, Gaspero A, Parikh F, Gartrell-Corrado RD, Hart TD, Laoui D, Van Ginderachter JA, Dharmaraj N, Spanos WC, Saenger Y, Young S, Sikora AG.

J Immunother Cancer. 2019 Aug 13;7(1):216. doi: 10.1186/s40425-019-0698-6.

8.

Epigenetic loss of AOX1 expression via EZH2 leads to metabolic deregulations and promotes bladder cancer progression.

Vantaku V, Putluri V, Bader DA, Maity S, Ma J, Arnold JM, Rajapakshe K, Donepudi SR, von Rundstedt FC, Devarakonda V, Dubrulle J, Karanam B, McGuire SE, Stossi F, Jain AK, Coarfa C, Cao Q, Sikora AG, Villanueva H, Kavuri SM, Lotan Y, Sreekumar A, Putluri N.

Oncogene. 2019 Aug 5. doi: 10.1038/s41388-019-0902-7. [Epub ahead of print]

PMID:
31383940
9.

UDP-glucose 6-dehydrogenase regulates hyaluronic acid production and promotes breast cancer progression.

Arnold JM, Gu F, Ambati CR, Rasaily U, Ramirez-Pena E, Joseph R, Manikkam M, San Martin R, Charles C, Pan Y, Chatterjee SS, Den Hollander P, Nagi C, Sikora AG, Rowley D, Putluri N, Karanam B, Mani SA, Sreekumar A.

Oncogene. 2019 Jul 15. doi: 10.1038/s41388-019-0885-4. [Epub ahead of print]

10.

The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of squamous cell carcinoma of the head and neck (HNSCC).

Cohen EEW, Bell RB, Bifulco CB, Burtness B, Gillison ML, Harrington KJ, Le QT, Lee NY, Leidner R, Lewis RL, Licitra L, Mehanna H, Mell LK, Raben A, Sikora AG, Uppaluri R, Whitworth F, Zandberg DP, Ferris RL.

J Immunother Cancer. 2019 Jul 15;7(1):184. doi: 10.1186/s40425-019-0662-5.

11.

ERR1 and PGC1α associated mitochondrial alterations correlate with pan-cancer disparity in African Americans.

Piyarathna DWB, Balasubramanian A, Arnold JM, Lloyd SM, Karanam B, Castro P, Ittmann MM, Putluri N, Navone N, Jones JA, Yu W, Sandulache VC, Sikora AG, Michailidis G, Sreekumar A.

J Clin Invest. 2019 Mar 28;129(6):2351-2356. doi: 10.1172/JCI127579.

12.

Swallowing Function in Survivors of Oropharyngeal Cancer Is Associated With Advanced T Classification.

Harms A, Kansara S, Stach C, Richardson PA, Chen G, Lai S, Sikora AG, Parke R, Donovan D, Chiao E, Skinner H, Sandulache VC.

Ann Otol Rhinol Laryngol. 2019 Aug;128(8):696-703. doi: 10.1177/0003489419839091. Epub 2019 Mar 27.

PMID:
30913911
13.

Anti-tumor immunity induced by ectopic expression of viral antigens is transient and limited by immune escape.

Dharmaraj N, Piotrowski SL, Huang C, Newton JM, Golfman LS, Hanoteau A, Koshy ST, Li AW, Pulikkathara MX, Zhang B, Burks JK, Mooney DJ, Lei YL, Sikora AG, Young S.

Oncoimmunology. 2019 Feb 6;8(4):e1568809. doi: 10.1080/2162402X.2019.1568809. eCollection 2019.

PMID:
30906661
14.

Multi-omics Integration Analysis Robustly Predicts High-Grade Patient Survival and Identifies CPT1B Effect on Fatty Acid Metabolism in Bladder Cancer.

Vantaku V, Dong J, Ambati CR, Perera D, Donepudi SR, Amara CS, Putluri V, Ravi SS, Robertson MJ, Piyarathna DWB, Villanueva M, von Rundstedt FC, Karanam B, Ballester LY, Terris MK, Bollag RJ, Lerner SP, Apolo AB, Villanueva H, Lee M, Sikora AG, Lotan Y, Sreekumar A, Coarfa C, Putluri N.

Clin Cancer Res. 2019 Jun 15;25(12):3689-3701. doi: 10.1158/1078-0432.CCR-18-1515. Epub 2019 Mar 7.

PMID:
30846479
15.

Associations between pre-, post-, and peri-operative variables and health resource use following surgery for head and neck cancer.

Badr H, Sobrero M, Chen J, Kotz T, Genden E, Sikora AG, Miles B.

Oral Oncol. 2019 Mar;90:102-108. doi: 10.1016/j.oraloncology.2019.02.004. Epub 2019 Feb 11.

PMID:
30846167
16.

HRAS-driven cancer cells are vulnerable to TRPML1 inhibition.

Jung J, Cho KJ, Naji AK, Clemons KN, Wong CO, Villanueva M, Gregory S, Karagas NE, Tan L, Liang H, Rousseau MA, Tomasevich KM, Sikora AG, Levental I, van der Hoeven D, Zhou Y, Hancock JF, Venkatachalam K.

EMBO Rep. 2019 Apr;20(4). pii: e46685. doi: 10.15252/embr.201846685. Epub 2019 Feb 20.

PMID:
30787043
17.

Histoepigenetic analysis of HPV- and tobacco-associated head and neck cancer identifies both subtype-specific and common therapeutic targets despite divergent microenvironments.

Carrero I, Liu HC, Sikora AG, Milosavljevic A.

Oncogene. 2019 May;38(19):3551-3568. doi: 10.1038/s41388-018-0659-4. Epub 2019 Jan 17.

18.

Tumor microenvironment modulation enhances immunologic benefit of chemoradiotherapy.

Hanoteau A, Newton JM, Krupar R, Huang C, Liu HC, Gaspero A, Gartrell RD, Saenger YM, Hart TD, Santegoets SJ, Laoui D, Spanos C, Parikh F, Jayaraman P, Zhang B, Van der Burg SH, Van Ginderachter JA, Melief CJM, Sikora AG.

J Immunother Cancer. 2019 Jan 15;7(1):10. doi: 10.1186/s40425-018-0485-9.

19.

Trends in Risks for Second Primary Cancers Associated With Index Human Papillomavirus-Associated Cancers.

Suk R, Mahale P, Sonawane K, Sikora AG, Chhatwal J, Schmeler KM, Sigel K, Cantor SB, Chiao EY, Deshmukh AA.

JAMA Netw Open. 2018 Sep 7;1(5):e181999. doi: 10.1001/jamanetworkopen.2018.1999.

20.

TGF-β1 programmed myeloid-derived suppressor cells (MDSC) acquire immune-stimulating and tumor killing activity capable of rejecting established tumors in combination with radiotherapy.

Jayaraman P, Parikh F, Newton JM, Hanoteau A, Rivas C, Krupar R, Rajapakshe K, Pathak R, Kanthaswamy K, MacLaren C, Huang S, Coarfa C, Spanos C, Edwards DP, Parihar R, Sikora AG.

Oncoimmunology. 2018 Jul 26;7(10):e1490853. doi: 10.1080/2162402X.2018.1490853. eCollection 2018.

21.

The chick chorioallantoic membrane (CAM) as a versatile patient-derived xenograft (PDX) platform for precision medicine and preclinical research.

DeBord LC, Pathak RR, Villaneuva M, Liu HC, Harrington DA, Yu W, Lewis MT, Sikora AG.

Am J Cancer Res. 2018 Aug 1;8(8):1642-1660. eCollection 2018. Review.

22.

Treatment Patterns in Veterans with Laryngeal and Oropharyngeal Cancer and Impact on Survival.

Richardson PA, Kansara S, Chen GG, Sabichi A, Sikora AG, Parke RB, Donovan DT, Chiao E, Sandulache VC.

Laryngoscope Investig Otolaryngol. 2018 Aug 9;3(4):275-282. doi: 10.1002/lio2.170. eCollection 2018 Aug.

23.

Anticancer therapy and lung injury: molecular mechanisms.

Li L, Mok H, Jhaveri P, Bonnen MD, Sikora AG, Eissa NT, Komaki RU, Ghebre YT.

Expert Rev Anticancer Ther. 2018 Oct;18(10):1041-1057. doi: 10.1080/14737140.2018.1500180. Epub 2018 Jul 23. Review.

24.
25.

Transcutaneously refillable, 3D-printed biopolymeric encapsulation system for the transplantation of endocrine cells.

Farina M, Chua CYX, Ballerini A, Thekkedath U, Alexander JF, Rhudy JR, Torchio G, Fraga D, Pathak RR, Villanueva M, Shin CS, Niles JA, Sesana R, Demarchi D, Sikora AG, Acharya GS, Gaber AO, Nichols JE, Grattoni A.

Biomaterials. 2018 Sep;177:125-138. doi: 10.1016/j.biomaterials.2018.05.047. Epub 2018 May 30.

PMID:
29886385
26.

Tracheoesophageal Prosthesis Use Is Associated With Improved Overall Quality of Life in Veterans With Laryngeal Cancer.

Patel RS, Mohr T, Hartman C, Stach C, Sikora AG, Zevallos JP, Sandulache VC.

Ann Otol Rhinol Laryngol. 2018 Jul;127(7):421-428. doi: 10.1177/0003489418772067. Epub 2018 May 14.

PMID:
29756480
27.

Non-Invasive Radiofrequency Field Treatment of 4T1 Breast Tumors Induces T-cell Dependent Inflammatory Response.

Newton JM, Flores-Arredondo JH, Suki S, Ware MJ, Krzykawska-Serda M, Agha M, Law JJ, Sikora AG, Curley SA, Corr SJ.

Sci Rep. 2018 Feb 22;8(1):3474. doi: 10.1038/s41598-018-21719-w.

28.

STINGel: Controlled release of a cyclic dinucleotide for enhanced cancer immunotherapy.

Leach DG, Dharmaraj N, Piotrowski SL, Lopez-Silva TL, Lei YL, Sikora AG, Young S, Hartgerink JD.

Biomaterials. 2018 May;163:67-75. doi: 10.1016/j.biomaterials.2018.01.035. Epub 2018 Feb 6.

29.

In silico analysis of anti-leukemia immune response and immune evasion in acute myeloid leukemia.

Krupar R, Schreiber C, Offermann A, Lengerke C, Sikora AG, Thorns C, Perner S.

Leuk Lymphoma. 2018 Oct;59(10):2493-2496. doi: 10.1080/10428194.2018.1434883. Epub 2018 Feb 12. No abstract available.

PMID:
29431550
30.

The Patient Who Continues to Smoke On-Treatment: An Ethical Dilemma.

Patro A, Guerrini CJ, Huang AT, Sikora AG.

Otolaryngol Head Neck Surg. 2018 Mar;158(3):469-472. doi: 10.1177/0194599817752634. Epub 2018 Jan 16. No abstract available.

PMID:
29337655
31.

Immunometabolic Determinants of Chemoradiotherapy Response and Survival in Head and Neck Squamous Cell Carcinoma.

Krupar R, Hautmann MG, Pathak RR, Varier I, McLaren C, Gaag D, Hellerbrand C, Evert M, Laban S, Idel C, Sandulache V, Perner S, Bosserhoff AK, Sikora AG.

Am J Pathol. 2018 Jan;188(1):72-83. doi: 10.1016/j.ajpath.2017.09.013. Epub 2017 Oct 27.

32.

Oral Human Papillomavirus Infection: Differences in Prevalence Between Sexes and Concordance With Genital Human Papillomavirus Infection, NHANES 2011 to 2014.

Sonawane K, Suk R, Chiao EY, Chhatwal J, Qiu P, Wilkin T, Nyitray AG, Sikora AG, Deshmukh AA.

Ann Intern Med. 2017 Nov 21;167(10):714-724. doi: 10.7326/M17-1363. Epub 2017 Oct 17.

33.

Vascular Aging: Implications for Cardiovascular Disease and Therapy.

Ghebre YT, Yakubov E, Wong WT, Krishnamurthy P, Sayed N, Sikora AG, Bonnen MD.

Transl Med (Sunnyvale). 2016 Dec;6(4). pii: 183. doi: 10.4172/2161-1025.1000183. Epub 2016 Aug 30.

34.

Tenascin-C and Integrin α9 Mediate Interactions of Prostate Cancer with the Bone Microenvironment.

San Martin R, Pathak R, Jain A, Jung SY, Hilsenbeck SG, Piña-Barba MC, Sikora AG, Pienta KJ, Rowley DR.

Cancer Res. 2017 Nov 1;77(21):5977-5988. doi: 10.1158/0008-5472.CAN-17-0064. Epub 2017 Sep 15.

35.

Racial/ethnic variation in the prevalence of vaccine-related human papillomavirus genotypes.

Montealegre JR, Varier I, Bracamontes CG, Dillon LM, Guillaud M, Sikora AG, Follen M, Adler-Storthz K, Scheurer ME.

Ethn Health. 2019 Oct;24(7):804-815. doi: 10.1080/13557858.2017.1373073. Epub 2017 Sep 4.

PMID:
28870103
36.

Risk factors for oropharynx cancer in a cohort of HIV-infected veterans.

Chew EY, Hartman CM, Richardson PA, Zevallos JP, Sikora AG, Kramer JR, Chiao EY.

Oral Oncol. 2017 May;68:60-66. doi: 10.1016/j.oraloncology.2017.03.004. Epub 2017 Mar 23.

37.

Therapeutic Efficacy of Esomeprazole in Cotton Smoke-Induced Lung Injury Model.

Nelson C, Lee J, Ko K, Sikora AG, Bonnen MD, Enkhbaatar P, Ghebre YT.

Front Pharmacol. 2017 Jan 26;8:16. doi: 10.3389/fphar.2017.00016. eCollection 2017.

38.

MAGE expression in head and neck squamous cell carcinoma primary tumors, lymph node metastases and respective recurrences-implications for immunotherapy.

Laban S, Giebel G, Klümper N, Schröck A, Doescher J, Spagnoli G, Thierauf J, Theodoraki MN, Remark R, Gnjatic S, Krupar R, Sikora AG, Litjens G, Grabe N, Kristiansen G, Bootz F, Schuler PJ, Brunner C, Brägelmann J, Hoffmann TK, Perner S.

Oncotarget. 2017 Feb 28;8(9):14719-14735. doi: 10.18632/oncotarget.14830.

39.

Factors Influencing Head and Neck Surgical Oncologists' Transition from Curative to Palliative Treatment Goals.

Liao K, Blumenthal-Barby J, Sikora AG.

Otolaryngol Head Neck Surg. 2017 Jan;156(1):46-51. doi: 10.1177/0194599816667712. Epub 2016 Oct 3. Review.

PMID:
27625024
40.

Racial disparities in incidence of human papillomavirus-associated oropharyngeal cancer in an urban population.

Ramer I, Varier I, Zhang D, Demicco EG, Posner MR, Misiukiewicz K, Genden EM, Miles BA, Teng MS, Sikora AG.

Cancer Epidemiol. 2016 Oct;44:91-95. doi: 10.1016/j.canep.2016.07.004. Epub 2016 Aug 9.

PMID:
27518158
41.

Therapeutic HPV Cancer Vaccine Targeted to CD40 Elicits Effective CD8+ T-cell Immunity.

Yin W, Duluc D, Joo H, Xue Y, Gu C, Wang Z, Wang L, Ouedraogo R, Oxford L, Clark A, Parikh F, Kim-Schulze S, Thompson-Snipes L, Lee SY, Beauregard C, Woo JH, Zurawski S, Sikora AG, Zurawski G, Oh S.

Cancer Immunol Res. 2016 Oct;4(10):823-834. Epub 2016 Aug 2.

42.

Immunotherapy and Checkpoint Inhibitors in Recurrent and Metastatic Head and Neck Cancer.

Hashemi-Sadraei N, Sikora AG, Brizel DM.

Am Soc Clin Oncol Educ Book. 2016;35:e277-82. doi: 10.14694/EDBK_157801. Review.

43.

Oncologic outcomes of surgically treated early-stage oropharyngeal squamous cell carcinoma.

Kass JI, Giraldez L, Gooding W, Choby G, Kim S, Miles B, Teng M, Sikora AG, Johnson JT, Myers EN, Duvvuri U, Genden EM, Ferris RL.

Head Neck. 2016 Oct;38(10):1467-71. doi: 10.1002/hed.24456. Epub 2016 Apr 15.

PMID:
27080244
44.

Clinical characteristics and outcomes of oropharyngeal carcinoma related to high-risk non-human papillomavirus16 viral subtypes.

Varier I, Keeley BR, Krupar R, Patsias A, Dong J, Gupta N, Parasher AK, Genden EM, Miles BA, Teng M, Bakst RL, Gupta V, Misiukiewicz KJ, Chiao EY, Scheurer ME, Laban S, Zhang D, Ye F, Cui M, Demicco EG, Posner MR, Sikora AG.

Head Neck. 2016 Sep;38(9):1330-7. doi: 10.1002/hed.24442. Epub 2016 Apr 15.

PMID:
27080140
45.

5-Fluorouracil targets thymidylate synthase in the selective suppression of TH17 cell differentiation.

Wang J, Peng L, Zhang R, Zheng Z, Chen C, Cheung KL, Cui M, Bian G, Xu F, Chiang D, Hu Y, Chen Y, Lu G, Yang J, Zhang H, Yang J, Zhu H, Chen SH, Liu K, Zhou MM, Sikora AG, Li L, Jiang B, Xiong H.

Oncotarget. 2016 Apr 12;7(15):19312-26. doi: 10.18632/oncotarget.8344.

46.

Expression and clinical significance of MAGE and NY-ESO-1 cancer-testis antigens in adenoid cystic carcinoma of the head and neck.

Veit JA, Heine D, Thierauf J, Lennerz J, Shetty S, Schuler PJ, Whiteside T, Beutner D, Meyer M, Grünewald I, Ritter G, Gnjatic S, Sikora AG, Hoffmann TK, Laban S.

Head Neck. 2016 Jul;38(7):1008-16. doi: 10.1002/hed.24403. Epub 2016 Feb 13.

47.

The In Ovo Chick Chorioallantoic Membrane (CAM) Assay as an Efficient Xenograft Model of Hepatocellular Carcinoma.

Li M, Pathak RR, Lopez-Rivera E, Friedman SL, Aguirre-Ghiso JA, Sikora AG.

J Vis Exp. 2015 Oct 9;(104). doi: 10.3791/52411.

48.

High-resolution microendoscope imaging of inverted papilloma and normal sinonasal mucosa: evaluation of interobserver concordance.

Parasher AK, Kidwai SM, Schorn VJ, Goljo E, Weinberg AD, Richards-Kortum R, Sikora AG, Iloreta AM, Govindaraj S, Miles BA.

Int Forum Allergy Rhinol. 2015 Dec;5(12):1136-40. doi: 10.1002/alr.21603. Epub 2015 Jul 30.

PMID:
26228817
49.

Prognostic Implication of Persistent Human Papillomavirus Type 16 DNA Detection in Oral Rinses for Human Papillomavirus-Related Oropharyngeal Carcinoma.

Rettig EM, Wentz A, Posner MR, Gross ND, Haddad RI, Gillison ML, Fakhry C, Quon H, Sikora AG, Stott WJ, Lorch JH, Gourin CG, Guo Y, Xiao W, Miles BA, Richmon JD, Andersen PE, Misiukiewicz KJ, Chung CH, Gerber JE, Rajan SD, D'Souza G.

JAMA Oncol. 2015 Oct;1(7):907-15. doi: 10.1001/jamaoncol.2015.2524.

PMID:
26226294
50.

Operative margin control with high-resolution optical microendoscopy for head and neck squamous cell carcinoma.

Miles BA, Patsias A, Quang T, Polydorides AD, Richards-Kortum R, Sikora AG.

Laryngoscope. 2015 Oct;125(10):2308-16. doi: 10.1002/lary.25400. Epub 2015 Jun 9.

PMID:
26059758

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