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Items: 50

1.

A unique model for SDH-deficient GIST: an endocrine-related cancer

Powers JF, Cochran B, Baleja JD, Sikes HD, Zhang X, Lomakin I, Langford T, Stein KT, Tischler AS.

Endocr Relat Cancer. 2018 Nov 1;25(11):943–954. doi: 10.1530/ERC-18-0115.

PMID:
30306789
2.

Mitochondrial H2O2 Generation Using a Tunable Chemogenetic Tool To Perturb Redox Homeostasis in Human Cells and Induce Cell Death.

Stein KT, Moon SJ, Sikes HD.

ACS Synth Biol. 2018 Sep 21;7(9):2037-2044. doi: 10.1021/acssynbio.8b00174. Epub 2018 Aug 31.

PMID:
30138563
3.

Improved Ordering in Low Molecular Weight Protein-Polymer Conjugates Through Oligomerization of the Protein Block.

Paloni JM, Miller EA, Sikes HD, Olsen BD.

Biomacromolecules. 2018 Sep 10;19(9):3814-3824. doi: 10.1021/acs.biomac.8b00928. Epub 2018 Aug 22.

PMID:
30132651
4.

Monitoring the action of redox-directed cancer therapeutics using a human peroxiredoxin-2-based probe.

Langford TF, Huang BK, Lim JB, Moon SJ, Sikes HD.

Nat Commun. 2018 Aug 7;9(1):3145. doi: 10.1038/s41467-018-05557-y.

5.

A unique model for SDH-deficient GIST: an endocrine-related cancer.

Powers JF, Cochran B, Baleja JD, Sikes HD, Zhang X, Lomakin I, Langford T, Stein KT, Tischler AS.

Endocr Relat Cancer. 2018 Nov;25(11):943-954. doi: 10.1530/ERC-18-0115. Epub 2018 Jul 2.

PMID:
29967109
6.

Design Principles for Enhancing Sensitivity in Paper-Based Diagnostics via Large-Volume Processing.

Miller EA, Jabbour Al Maalouf Y, Sikes HD.

Anal Chem. 2018 Aug 7;90(15):9472-9479. doi: 10.1021/acs.analchem.8b02113. Epub 2018 Jul 10.

PMID:
29924932
7.

An examination of critical parameters in hybridization-based epigenotyping using magnetic microparticles.

Tam BE, Hao Y, Sikes HD.

Biotechnol Prog. 2018 Apr 25. doi: 10.1002/btpr.2644. [Epub ahead of print]

PMID:
29693329
8.

A mathematical analysis of Prx2-STAT3 disulfide exchange rate constants for a bimolecular reaction mechanism.

Langford TF, Deen WM, Sikes HD.

Free Radic Biol Med. 2018 May 20;120:239-245. doi: 10.1016/j.freeradbiomed.2018.03.039. Epub 2018 Mar 22.

PMID:
29574146
9.

Paper-based diagnostics in the antigen-depletion regime: High-density immobilization of rcSso7d-cellulose-binding domain fusion proteins for efficient target capture.

Miller EA, Baniya S, Osorio D, Al Maalouf YJ, Sikes HD.

Biosens Bioelectron. 2018 Apr 15;102:456-463. doi: 10.1016/j.bios.2017.11.050. Epub 2017 Nov 20.

PMID:
29182928
10.

Detection of Biomarkers of Periodontal Disease in Human Saliva Using Stabilized, Vertical Flow Immunoassays.

Yee EH, Lathwal S, Shah PP, Sikes HD.

ACS Sens. 2017 Nov 22;2(11):1589-1593. doi: 10.1021/acssensors.7b00745. Epub 2017 Nov 13.

PMID:
29090909
11.

Redox regulation: Scaffolding H2O2 signaling.

Sikes HD.

Nat Chem Biol. 2017 Jul 18;13(8):818-819. doi: 10.1038/nchembio.2432. No abstract available.

PMID:
28853734
12.

Engineering affinity agents for the detection of hemi-methylated CpG sites in DNA.

Tarn BE, Sung KJ, Sikes HD.

Mol Syst Des Eng. 2016 Oct 1;1(3):273-277. doi: 10.1039/C6ME00073H. Epub 2016 Sep 7.

13.

Activity-based assessment of an engineered hyperthermophilic protein as a capture agent in paper-based diagnostic tests.

Miller EA, Traxlmayr MW, Shen J, Sikes HD.

Mol Syst Des Eng. 2016 Dec 1;1(4):377-381. doi: 10.1039/C6ME00032K. Epub 2016 Jun 29.

14.

Modulating and Measuring Intracellular H2O2 Using Genetically Encoded Tools to Study Its Toxicity to Human Cells.

Huang BK, Stein KT, Sikes HD.

ACS Synth Biol. 2016 Dec 16;5(12):1389-1395. Epub 2016 Jul 26.

PMID:
27428287
15.

Portable, Constriction-Expansion Blood Plasma Separation and Polymerization-Based Malaria Detection.

Shatova TA, Lathwal S, Engle MR, Sikes HD, Jensen KF.

Anal Chem. 2016 Aug 2;88(15):7627-32. doi: 10.1021/acs.analchem.6b01355. Epub 2016 Jul 13.

PMID:
27366819
16.

Using nanobiotechnology to increase the prevalence of epigenotyping assays in precision medicine.

Heimer BW, Tam BE, Minkovsky A, Sikes HD.

Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2017 Jan;9(1). doi: 10.1002/wnan.1407. Epub 2016 Apr 29. Review.

PMID:
27126368
17.

Assessment of colorimetric amplification methods in a paper-based immunoassay for diagnosis of malaria.

Lathwal S, Sikes HD.

Lab Chip. 2016 Apr 21;16(8):1374-82. doi: 10.1039/c6lc00058d.

PMID:
27001468
18.

Using Sensors and Generators of H2O2 to Elucidate the Toxicity Mechanism of Piperlongumine and Phenethyl Isothiocyanate.

Huang BK, Langford TF, Sikes HD.

Antioxid Redox Signal. 2016 Jun 1;24(16):924-38. doi: 10.1089/ars.2015.6482.

19.

A Method for Designing Instrument-Free Quantitative Immunoassays.

Lathwal S, Sikes HD.

Anal Chem. 2016 Mar 15;88(6):3194-202. doi: 10.1021/acs.analchem.5b04538. Epub 2016 Feb 24.

PMID:
26878154
20.

UV-Vis/FT-NIR in situ monitoring of visible-light induced polymerization of PEGDA hydrogels initiated by eosin/triethanolamine/O2.

Kaastrup K, Aguirre-Soto A, Wang C, Bowman CN, Stansbury J, Sikes HD.

Polym Chem. 2016;7(3):592-602. Epub 2015 Nov 13.

21.

Using photo-initiated polymerization reactions to detect molecular recognition.

Kaastrup K, Sikes HD.

Chem Soc Rev. 2016 Feb 7;45(3):532-45. doi: 10.1039/c5cs00205b. Review.

PMID:
26671512
22.

Addressing Barriers to the Development and Adoption of Rapid Diagnostic Tests in Global Health.

Miller E, Sikes HD.

Nanobiomedicine (Rij). 2015;2. pii: 6. Epub 2015 Jun 29.

23.

Interpreting Heterogeneity in Response of Cells Expressing a Fluorescent Hydrogen Peroxide Biosensor.

Huang BK, Ali S, Stein KT, Sikes HD.

Biophys J. 2015 Nov 17;109(10):2148-58. doi: 10.1016/j.bpj.2015.08.053.

24.

A reaction-diffusion model of cytosolic hydrogen peroxide.

Lim JB, Langford TF, Huang BK, Deen WM, Sikes HD.

Free Radic Biol Med. 2016 Jan;90:85-90. doi: 10.1016/j.freeradbiomed.2015.11.005. Epub 2015 Nov 10.

PMID:
26561774
25.

Characterization and directed evolution of a methyl-binding domain protein for high-sensitivity DNA methylation analysis.

Heimer BW, Tam BE, Sikes HD.

Protein Eng Des Sel. 2015 Dec;28(12):543-51. doi: 10.1093/protein/gzv046. Epub 2015 Sep 18.

26.

Insights into electron leakage in the reaction cycle of cytochrome P450 BM3 revealed by kinetic modeling and mutagenesis.

Lim JB, Barker KA, Eller KA, Jiang L, Molina V, Saifee JF, Sikes HD.

Protein Sci. 2015 Nov;24(11):1874-83. doi: 10.1002/pro.2793. Epub 2015 Sep 9.

27.

Staged Inertial Microfluidic Focusing for Complex Fluid Enrichment.

Reece AE, Kaastrup K, Sikes HD, Oakey J.

RSC Adv. 2015;5:53857-53864.

28.

Analysis of the lifetime and spatial localization of hydrogen peroxide generated in the cytosol using a reduced kinetic model.

Lim JB, Huang BK, Deen WM, Sikes HD.

Free Radic Biol Med. 2015 Dec;89:47-53. doi: 10.1016/j.freeradbiomed.2015.07.009. Epub 2015 Jul 11.

PMID:
26169725
29.

Use of a genetically encoded hydrogen peroxide sensor for whole cell screening of enzyme activity.

Lim JB, Sikes HD.

Protein Eng Des Sel. 2015 Mar;28(3):79-83. doi: 10.1093/protein/gzv003.

PMID:
25691762
30.

Editorial overview: analytical biotechnology.

Sikes HD, Zamboni N.

Curr Opin Biotechnol. 2015 Feb;31:iv-vi. doi: 10.1016/j.copbio.2014.12.001. Epub 2014 Dec 16. No abstract available.

PMID:
25529264
31.

Quantifying intracellular hydrogen peroxide perturbations in terms of concentration.

Huang BK, Sikes HD.

Redox Biol. 2014;2:955-62. doi: 10.1016/j.redox.2014.08.001. Epub 2014 Aug 6.

32.

Polymerization-based signal amplification for paper-based immunoassays.

Badu-Tawiah AK, Lathwal S, Kaastrup K, Al-Sayah M, Christodouleas DC, Smith BS, Whitesides GM, Sikes HD.

Lab Chip. 2015 Feb 7;15(3):655-9. doi: 10.1039/c4lc01239a.

PMID:
25427131
33.

In-depth characterization of the fluorescent signal of HyPer, a probe for hydrogen peroxide, in bacteria exposed to external oxidative stress.

Lim JB, Barker KA, Huang BK, Sikes HD.

J Microbiol Methods. 2014 Nov;106:33-39. doi: 10.1016/j.mimet.2014.07.038. Epub 2014 Aug 8.

PMID:
25109249
34.

Evaluating the sensitivity of hybridization-based epigenotyping using a methyl binding domain protein.

Heimer BW, Shatova TA, Lee JK, Kaastrup K, Sikes HD.

Analyst. 2014 Aug 7;139(15):3695-701. doi: 10.1039/c4an00667d.

35.

Balancing the initiation and molecular recognition capabilities of eosin macroinitiators of polymerization-based signal amplification reactions.

Lee JK, Sikes HD.

Macromol Rapid Commun. 2014 May;35(10):981-6. doi: 10.1002/marc.201400035. Epub 2014 Mar 26.

PMID:
24677679
36.

Impact of dissociation constant on the detection sensitivity of polymerization-based signal amplification reactions.

Kaastrup K, Chan L, Sikes HD.

Anal Chem. 2013 Sep 3;85(17):8055-60. doi: 10.1021/ac4018988. Epub 2013 Aug 22.

PMID:
23919833
37.
38.

Systematic study of fluorescein-functionalized macrophotoinitiators for colorimetric bioassays.

Lee JK, Heimer BW, Sikes HD.

Biomacromolecules. 2012 Apr 9;13(4):1136-43. doi: 10.1021/bm300037t. Epub 2012 Mar 22.

PMID:
22404188
39.

Functional heterologous expression and purification of a mammalian methyl-CpG binding domain in suitable yield for DNA methylation profiling assays.

Boyd ME, Heimer BW, Sikes HD.

Protein Expr Purif. 2012 Apr;82(2):332-8. doi: 10.1016/j.pep.2012.01.016. Epub 2012 Feb 2.

PMID:
22326799
40.

Antigen detection using polymerization-based amplification.

Sikes HD, Jenison R, Bowman CN.

Lab Chip. 2009 Mar 7;9(5):653-6. doi: 10.1039/b816198d. Epub 2008 Dec 8.

PMID:
19224013
41.

Visual detection of labeled oligonucleotides using visible-light-polymerization-based amplification.

Hansen RR, Sikes HD, Bowman CN.

Biomacromolecules. 2008 Jan;9(1):355-62. Epub 2007 Dec 1.

PMID:
18052028
42.

Using polymeric materials to generate an amplified response to molecular recognition events.

Sikes HD, Hansen RR, Johnson LM, Jenison R, Birks JW, Rowlen KL, Bowman CN.

Nat Mater. 2008 Jan;7(1):52-6. Epub 2007 Oct 28.

43.

E-box regulation of gonadotropin-releasing hormone (GnRH) receptor expression in immortalized gonadotrope cells.

Resuehr D, Wildemann U, Sikes H, Olcese J.

Mol Cell Endocrinol. 2007 Nov 15;278(1-2):36-43. Epub 2007 Aug 30.

PMID:
17928134
45.
46.

Interfacial electron-transfer kinetics of ferrocene through oligophenyleneethynylene bridges attached to gold electrodes as constituents of self-assembled monolayers: observation of a nonmonotonic distance dependence.

Smalley JF, Sachs SB, Chidsey CE, Dudek SP, Sikes HD, Creager SE, Yu CJ, Feldberg SW, Newton MD.

J Am Chem Soc. 2004 Nov 10;126(44):14620-30.

PMID:
15521782
47.
48.

Rapid electron tunneling through oligophenylenevinylene bridges.

Sikes HD, Smalley JF, Dudek SP, Cook AR, Newton MD, Chidsey CE, Feldberg SW.

Science. 2001 Feb 23;291(5508):1519-23.

49.

Two-dimensional melting of an anisotropic crystal observed at the molecular level

Sikes HD, Schwartz DK.

Science. 1997 Nov 28;278(5343):1604-7.

50.

Fiber-optic hysteroscopy: an improved method for viewing the interior of the uterus.

Norment SB, Sikes H.

N C Med J. 1970 Jul;31(7):251-4. No abstract available.

PMID:
5270524

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