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Items: 21

1.

The mitochondrial complex V-associated large-conductance inner membrane current is regulated by cyclosporine and dexpramipexole.

Alavian KN, Dworetzky SI, Bonanni L, Zhang P, Sacchetti S, Li H, Signore AP, Smith PJ, Gribkoff VK, Jonas EA.

Mol Pharmacol. 2015 Jan;87(1):1-8. doi: 10.1124/mol.114.095661. Epub 2014 Oct 20.

2.

Effects of dexpramipexole on brain mitochondrial conductances and cellular bioenergetic efficiency.

Alavian KN, Dworetzky SI, Bonanni L, Zhang P, Sacchetti S, Mariggio MA, Onofrj M, Thomas A, Li H, Mangold JE, Signore AP, Demarco U, Demady DR, Nabili P, Lazrove E, Smith PJ, Gribkoff VK, Jonas EA.

Brain Res. 2012 Mar 29;1446:1-11. doi: 10.1016/j.brainres.2012.01.046. Epub 2012 Jan 28.

3.

HSP27: mechanisms of cellular protection against neuronal injury.

Stetler RA, Gao Y, Signore AP, Cao G, Chen J.

Curr Mol Med. 2009 Sep;9(7):863-72. Review.

4.

Calcium dysregulation induces apoptosis-inducing factor release: cross-talk between PARP-1- and calpain-signaling pathways.

Vosler PS, Sun D, Wang S, Gao Y, Kintner DB, Signore AP, Cao G, Chen J.

Exp Neurol. 2009 Aug;218(2):213-20. doi: 10.1016/j.expneurol.2009.04.032. Epub 2009 May 7.

5.

Rapidly increased neuronal mitochondrial biogenesis after hypoxic-ischemic brain injury.

Yin W, Signore AP, Iwai M, Cao G, Gao Y, Chen J.

Stroke. 2008 Nov;39(11):3057-63. doi: 10.1161/STROKEAHA.108.520114. Epub 2008 Aug 21.

6.

Cellular NAD replenishment confers marked neuroprotection against ischemic cell death: role of enhanced DNA repair.

Wang S, Xing Z, Vosler PS, Yin H, Li W, Zhang F, Signore AP, Stetler RA, Gao Y, Chen J.

Stroke. 2008 Sep;39(9):2587-95. doi: 10.1161/STROKEAHA.107.509158. Epub 2008 Jul 10.

7.

Leptin neuroprotection in the CNS: mechanisms and therapeutic potentials.

Signore AP, Zhang F, Weng Z, Gao Y, Chen J.

J Neurochem. 2008 Sep;106(5):1977-90. doi: 10.1111/j.1471-4159.2008.05457.x. Epub 2008 May 3. Review.

8.

Leptin protects against 6-hydroxydopamine-induced dopaminergic cell death via mitogen-activated protein kinase signaling.

Weng Z, Signore AP, Gao Y, Wang S, Zhang F, Hastings T, Yin XM, Chen J.

J Biol Chem. 2007 Nov 23;282(47):34479-91. Epub 2007 Sep 25.

9.

Neuroprotective effects of leptin against ischemic injury induced by oxygen-glucose deprivation and transient cerebral ischemia.

Zhang F, Wang S, Signore AP, Chen J.

Stroke. 2007 Aug;38(8):2329-36. Epub 2007 Jun 28.

PMID:
17600230
10.

Preconditioning suppresses inflammation in neonatal hypoxic ischemia via Akt activation.

Yin W, Signore AP, Iwai M, Cao G, Gao Y, Johnnides MJ, Hickey RW, Chen J.

Stroke. 2007 Mar;38(3):1017-24. Epub 2007 Feb 1.

PMID:
17272774
11.

Bcl-2 enhances neurogenesis and inhibits apoptosis of newborn neurons in adult rat brain following a transient middle cerebral artery occlusion.

Zhang R, Xue YY, Lu SD, Wang Y, Zhang LM, Huang YL, Signore AP, Chen J, Sun FY.

Neurobiol Dis. 2006 Nov;24(2):345-56. Epub 2006 Sep 25.

PMID:
16996745
12.

Neuroprotection against focal ischemic brain injury by the peroxisome proliferator-activated receptor-gamma agonist rosiglitazone.

Luo Y, Yin W, Signore AP, Zhang F, Hong Z, Wang S, Graham SH, Chen J.

J Neurochem. 2006 Apr;97(2):435-48. Epub 2006 Mar 15.

13.

Erythropoietin protects CA1 neurons against global cerebral ischemia in rat: potential signaling mechanisms.

Zhang F, Signore AP, Zhou Z, Wang S, Cao G, Chen J.

J Neurosci Res. 2006 May 15;83(7):1241-51.

PMID:
16511866
14.

Erythropoietin protects against 6-hydroxydopamine-induced dopaminergic cell death.

Signore AP, Weng Z, Hastings T, Van Laar AD, Liang Q, Lee YJ, Chen J.

J Neurochem. 2006 Jan;96(2):428-43. Epub 2005 Dec 8.

15.

TAT-mediated delivery of Bcl-xL protein is neuroprotective against neonatal hypoxic-ischemic brain injury via inhibition of caspases and AIF.

Yin W, Cao G, Johnnides MJ, Signore AP, Luo Y, Hickey RW, Chen J.

Neurobiol Dis. 2006 Feb;21(2):358-71. Epub 2005 Sep 6.

PMID:
16140540
16.

Ischemic preconditioning in the rat brain enhances the repair of endogenous oxidative DNA damage by activating the base-excision repair pathway.

Li W, Luo Y, Zhang F, Signore AP, Gobbel GT, Simon RP, Chen J.

J Cereb Blood Flow Metab. 2006 Feb;26(2):181-98.

PMID:
16001017
17.

Neuroprotection against focal ischemic brain injury by inhibition of c-Jun N-terminal kinase and attenuation of the mitochondrial apoptosis-signaling pathway.

Gao Y, Signore AP, Yin W, Cao G, Yin XM, Sun F, Luo Y, Graham SH, Chen J.

J Cereb Blood Flow Metab. 2005 Jun;25(6):694-712.

PMID:
15716857
20.

Immunohistochemical localization of the INsP4 receptor GTPase-activating protein GAP1IP4BP in the rat brain.

Signore AP, O'Rourke F, Lu X, Feinstein MB, Yeh HH.

J Neurosci Res. 1999 Feb 1;55(3):321-8.

PMID:
10348663
21.

Functional recovery in hemiparkinsonian primates transplanted with polymer-encapsulated PC12 cells.

Aebischer P, Goddard M, Signore AP, Timpson RL.

Exp Neurol. 1994 Apr;126(2):151-8.

PMID:
7925816

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