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Items: 1 to 50 of 168

1.

Targeting ATM ameliorates mutant Huntingtin toxicity in cell and animal models of Huntington's disease.

Lu XH, Mattis VB, Wang N, Al-Ramahi I, van den Berg N, Fratantoni SA, Waldvogel H, Greiner E, Osmand A, Elzein K, Xiao J, Dijkstra S, de Pril R, Vinters HV, Faull R, Signer E, Kwak S, Marugan JJ, Botas J, Fischer DF, Svendsen CN, Munoz-Sanjuan I, Yang XW.

Sci Transl Med. 2014 Dec 24;6(268):268ra178. doi: 10.1126/scitranslmed.3010523.

PMID:
25540325
2.

Through postdoc eyes.

Signer E.

Res Microbiol. 2014 Jun;165(5):346-7. doi: 10.1016/j.resmic.2014.05.029. Epub 2014 May 21. No abstract available.

PMID:
24859142
3.

Comprehensive behavioral testing in the R6/2 mouse model of Huntington's disease shows no benefit from CoQ10 or minocycline.

Menalled LB, Patry M, Ragland N, Lowden PA, Goodman J, Minnich J, Zahasky B, Park L, Leeds J, Howland D, Signer E, Tobin AJ, Brunner D.

PLoS One. 2010 Mar 22;5(3):e9793. doi: 10.1371/journal.pone.0009793.

4.

Systematic behavioral evaluation of Huntington's disease transgenic and knock-in mouse models.

Menalled L, El-Khodor BF, Patry M, Suárez-Fariñas M, Orenstein SJ, Zahasky B, Leahy C, Wheeler V, Yang XW, MacDonald M, Morton AJ, Bates G, Leeds J, Park L, Howland D, Signer E, Tobin A, Brunner D.

Neurobiol Dis. 2009 Sep;35(3):319-36. doi: 10.1016/j.nbd.2009.05.007. Epub 2009 May 21.

5.

Historical aspects and present knowledge of idiopathic thrombocytopenic purpura.

Imbach P, Kühne T, Signer E.

Br J Haematol. 2002 Dec;119(4):894-900. No abstract available.

PMID:
12472565
6.

Positive-negative selection for homologous recombination in Arabidopsis.

Xiaohui Wang H, Viret JF, Eldridge A, Perera R, Signer ER, Chiurazzi M.

Gene. 2001 Jul 11;272(1-2):249-55.

PMID:
11470531
7.

Huntington's disease: the challenge for cell biologists.

Tobin AJ, Signer ER.

Trends Cell Biol. 2000 Dec;10(12):531-6. Review.

PMID:
11121745
8.

Are DNA profiles breed-specific? A pilot study in pigs.

Signer EN, Dubrova YE, Jeffreys AJ.

Anim Genet. 2000 Aug;31(4):273-6.

PMID:
11086537
9.

Increased withdrawal volume per deposit for pre-operative autologous blood donation in adolescents.

Erb T, Möller R, Christen P, Signer E, Frei FJ.

Vox Sang. 2000;78(4):231-4.

PMID:
10895096
10.

Chimaeric and constitutive DNA fingerprints in the common marmoset (Callithrix jacchus).

Signer EN, Anzenberger G, Jeffreys AJ.

Primates. 2000 Jan;41(1):49-61. doi: 10.1007/BF02557461.

PMID:
30545191
11.

DNA profiling reveals remarkably low genetic variability in a herd of SLA homozygous pigs.

Signer EN, Jeffreys AJ, Licence S, Miller R, Byrd P, Binns R.

Res Vet Sci. 1999 Oct;67(2):207-11.

PMID:
10502496
12.

Human minisatellites, repeat DNA instability and meiotic recombination.

Jeffreys AJ, Barber R, Bois P, Buard J, Dubrova YE, Grant G, Hollies CR, May CA, Neumann R, Panayi M, Ritchie AE, Shone AC, Signer E, Stead JD, Tamaki K.

Electrophoresis. 1999 Jun;20(8):1665-75. Review.

PMID:
10435430
13.

[25 years allogenic bone marrow transplantation in Basel: 1973-1998].

Passweg JR, Gratwohl A, Tichelli A, Hoffmann T, Nissen C, Kühne T, Favre G, Avoledo P, Cornu P, Herrmann R, Jeannet M, Osterwalder B, Sartorius J, Schifferli JA, Signer E, Stauffacher W, Speck B.

Schweiz Med Wochenschr. 1998 Oct 17;128(42):1568-74. German. No abstract available.

PMID:
9824884
14.

DNA fingerprinting Dolly.

Signer EN, Dubrova YE, Jeffreys AJ, Wilde C, Finch LM, Wells M, Peaker M.

Nature. 1998 Jul 23;394(6691):329-30. No abstract available.

PMID:
9690468
16.

Repeated treatment with horse antilymphocyte globulin for severe aplastic anaemia.

Tichelli A, Passweg J, Nissen C, Bargetzi M, Hoffmann T, Wodnar-Filipowicz A, Signer E, Speck B, Gratwohl A.

Br J Haematol. 1998 Feb;100(2):393-400.

PMID:
9488634
17.

Celiac disease transmitted by allogeneic non-T cell-depleted bone marrow transplantation.

Bargetzi MJ, Schönenberger A, Tichelli A, Fried R, Cathomas G, Signer E, Speck B, Gratwohl A.

Bone Marrow Transplant. 1997 Oct;20(7):607-9.

18.

Rapid genotyping of a pig minisatellite using long PCR.

Signer EN, Jeffreys AJ.

Anim Genet. 1997 Aug;28(4):311. No abstract available.

PMID:
9345733
19.

Enhancement of somatic intrachromosomal homologous recombination in Arabidopsis by the HO endonuclease.

Chiurazzi M, Ray A, Viret JF, Perera R, Wang XH, Lloyd AM, Signer ER.

Plant Cell. 1996 Nov;8(11):2057-66.

20.
21.

A panel of VNTR markers in pigs.

Signer EN, Gu F, Jeffreys AJ.

Mamm Genome. 1996 Jun;7(6):433-7.

PMID:
8662226
22.

Detection of an MboI RFLP at the porcine clotting factor IX locus and verification of sex linkage.

Signer EN, Armour JA, Jeffreys AJ.

Anim Genet. 1996 Apr;27(2):130. No abstract available.

PMID:
8856916
23.

Splenectomy as an adjuvant measure in the treatment of severe aplastic anaemia.

Speck B, Tichelli A, Widmer E, Harder F, Kissling M, Würsch A, Stebler Gysi C, Signer E, Bargetzi M, Orth B, Gratwohl A, Nissen C.

Br J Haematol. 1996 Mar;92(4):818-24.

PMID:
8616072
24.

[Autologous transplantation of hematopoietic precursor cells following CD34 selection].

Tichelli A, Gratwohl A, Bargetzi M, Nissen C, Wernli M, Herrmann R, Orth B, Signer E, Speck B.

Schweiz Med Wochenschr. 1996 Feb 10;126(6):201-6. German.

PMID:
8720723
25.

Arabidopsis mutants deficient in T-DNA integration.

Sonti RV, Chiurazzi M, Wong D, Davies CS, Harlow GR, Mount DW, Signer ER.

Proc Natl Acad Sci U S A. 1995 Dec 5;92(25):11786-90.

26.

Does monozygotic twinning occur in mice?

McLaren A, Molland P, Signer E.

Genet Res. 1995 Dec;66(3):195-202.

PMID:
8600018
28.

Immature B cells from human and mouse bone marrow can change their surface light chain expression.

Ghia P, Gratwohl A, Signer E, Winkler TH, Melchers F, Rolink AG.

Eur J Immunol. 1995 Nov;25(11):3108-14.

PMID:
7489750
29.

Activity of the yeast FLP recombinase in Arabidopsis.

Sonti RV, Tissier AF, Wong D, Viret JF, Signer ER.

Plant Mol Biol. 1995 Sep;28(6):1127-32.

PMID:
7548830
30.

Purification and characterization of a DNA strand transferase from broccoli.

Tissier AF, Lopez MF, Signer ER.

Plant Physiol. 1995 May;108(1):379-86.

31.

Childhood NHL in Switzerland: incidence and survival of 120 study and 42 non-study patients.

Wagner HP, Dingeldein-Bettler I, Berchthold W, Lüthy AR, Hirt A, Plüss HJ, Beck D, Wyss M, Signer E, Imbach P, et al.

Med Pediatr Oncol. 1995 May;24(5):281-6.

PMID:
7700178
32.

A somatic BRCA1 mutation in an ovarian tumour.

Hosking L, Trowsdale J, Nicolai H, Solomon E, Foulkes W, Stamp G, Signer E, Jeffreys A.

Nat Genet. 1995 Apr;9(4):343-4. No abstract available.

PMID:
7795636
33.

[Flow cytometry identification of CD34-positive cells].

Tichelli A, Kralj A, Huxol H, Schönenberger A, Rabaglio M, Borel J, Müller R, Bargetzi M, Gratwohl A, Signer E, et al.

Schweiz Med Wochenschr. 1995 Mar 4;125(9):400-4. German.

PMID:
7534431
34.

Termini and telomeres in T-DNA transformation.

Chiurazzi M, Signer ER.

Plant Mol Biol. 1994 Nov;26(3):923-34.

PMID:
8000005
35.

Rhizobium meliloti homologs of Escherichia coli mur genes.

Leach F, Wacks DB, Signer ER.

Gene. 1994 Oct 11;148(1):87-90.

PMID:
7926844
36.

DNA variability and parentage testing in captive Waldrapp ibises.

Signer EN, Schmidt CR, Jeffreys AJ.

Mol Ecol. 1994 Aug;3(4):291-300.

PMID:
7921356
37.

[How long should cyclosporin be administered following bone marrow transplantation?].

Gratwohl A, Tichelli A, Stauffer G, Passweg J, Pless M, Gengenbacher D, Buser U, Signer E, Haberthür C, Gimmi C, et al.

Schweiz Med Wochenschr. 1994 Jan 11;124(1-2):44-50. German.

PMID:
8296190
38.

A pseudoautosomal minisatellite in the pig.

Signer EN, Gu F, Gustavsson I, Andersson L, Jeffreys AJ.

Mamm Genome. 1994 Jan;5(1):48-51. No abstract available.

PMID:
8111129
39.

Digoxigenin labeling of RNA transcripts from multi- and single-locus DNA minisatellite probes.

Signer EN.

Methods Mol Biol. 1994;28:77-81. No abstract available.

PMID:
7509700
40.

Southern blot hybridization of digoxigenin-labeled RNA minisatellite probes and color detection.

Signer EN.

Methods Mol Biol. 1994;28:113-20. No abstract available.

PMID:
7509690
41.

Cytosine deaminase as a negative selective marker for Arabidopsis.

Perera RJ, Linard CG, Signer ER.

Plant Mol Biol. 1993 Nov;23(4):793-9. Erratum in: Plant Mol Biol 1994 Mar;24(5):832.

PMID:
8251632
42.

All-trans retinoic acid as an alternative to chemotherapy in the treatment of acute promyelocytic leukemia.

Kühne T, Imbach P, Signer E, Osterwalder B.

Pediatr Hematol Oncol. 1993 Oct-Dec;10(4):363-7.

PMID:
8292523
43.

[Acute spinal syndromes in children and adolescents].

Bode H, Bubl R, Hefti F, Signer E, Wyler F.

Klin Padiatr. 1993 Sep-Oct;205(5):345-50. German.

PMID:
8411900
44.

Epigenetic repeat-induced gene silencing (RIGS) in Arabidopsis.

Assaad FF, Tucker KL, Signer ER.

Plant Mol Biol. 1993 Sep;22(6):1067-85.

PMID:
8400126
45.

Gender and response to antilymphocyte globulin (ALG) for severe aplastic anaemia.

Nissen C, Gratwohl A, Tichelli A, Stebler C, Würsch A, Moser Y, Dalle Carbonare V, Signer E, Buser M, Ritz R, et al.

Br J Haematol. 1993 Feb;83(2):319-25.

PMID:
7681318
47.

Somatic and germinal recombination of a direct repeat in Arabidopsis.

Assaad FF, Signer ER.

Genetics. 1992 Oct;132(2):553-66.

48.

Cloning and Characterization of an Arabidopsis thaliana Topoisomerase I Gene.

Kieber JJ, Tissier AF, Signer ER.

Plant Physiol. 1992 Aug;99(4):1493-501.

49.

[Swiss Register for unrelated bone marrow donors: preliminary results].

Gratwohl A, Helg C, Chapuis B, Gmür J, Jeannet M, Kern M, Tichelli A, Speck B, Signer E, Wyss M, et al.

Schweiz Med Wochenschr. 1992 Jul 25;122(30):1117-22. German.

PMID:
1386684
50.

Morphology in patients with severe aplastic anemia treated with antilymphocyte globulin.

Tichelli A, Gratwohl A, Nissen C, Signer E, Stebler Gysi C, Speck B.

Blood. 1992 Jul 15;80(2):337-45.

PMID:
1627795

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