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Items: 8


Toxic Shock Syndrome Toxin 1 Evaluation and Antibiotic Impact in a Transgenic Model of Staphylococcal Soft Tissue Infection.

Sharma H, Turner CE, Siggins MK, El-Bahrawy M, Pichon B, Kearns A, Sriskandan S.

mSphere. 2019 Oct 9;4(5). pii: e00665-19. doi: 10.1128/mSphere.00665-19.


Impact of contusion injury on intramuscular emm1 group a streptococcus infection and lymphatic spread.

Lamb LE, Siggins MK, Scudamore C, Macdonald W, Turner CE, Lynskey NN, Tan LKK, Sriskandan S.

Virulence. 2018;9(1):1074-1084. doi: 10.1080/21505594.2018.1482180.


Multi-functional mechanisms of immune evasion by the streptococcal complement inhibitor C5a peptidase.

Lynskey NN, Reglinski M, Calay D, Siggins MK, Mason JC, Botto M, Sriskandan S.

PLoS Pathog. 2017 Aug 14;13(8):e1006493. doi: 10.1371/journal.ppat.1006493. eCollection 2017 Aug.


Identification of commonly expressed exoproteins and proteolytic cleavage events by proteomic mining of clinically relevant UK isolates of Staphylococcus aureus.

Smith DS, Siggins MK, Gierula M, Pichon B, Turner CE, Lynskey NN, Mosavie M, Kearns AM, Edwards RJ, Sriskandan S.

Microb Genom. 2016 Feb 23;2(2):e000049. doi: 10.1099/mgen.0.000049. eCollection 2016 Feb.


Differential Killing of Salmonella enterica Serovar Typhi by Antibodies Targeting Vi and Lipopolysaccharide O:9 Antigen.

Hart PJ, O'Shaughnessy CM, Siggins MK, Bobat S, Kingsley RA, Goulding DA, Crump JA, Reyburn H, Micoli F, Dougan G, Cunningham AF, MacLennan CA.

PLoS One. 2016 Jan 7;11(1):e0145945. doi: 10.1371/journal.pone.0145945. eCollection 2016.


PHiD-CV induces anti-Protein D antibodies but does not augment pulmonary clearance of nontypeable Haemophilus influenzae in mice.

Siggins MK, Gill SK, Langford PR, Li Y, Ladhani SN, Tregoning JS.

Vaccine. 2015 Sep 11;33(38):4954-61. doi: 10.1016/j.vaccine.2015.07.034. Epub 2015 Jul 26.


Differential timing of antibody-mediated phagocytosis and cell-free killing of invasive African Salmonella allows immune evasion.

Siggins MK, O'Shaughnessy CM, Pravin J, Cunningham AF, Henderson IR, Drayson MT, MacLennan CA.

Eur J Immunol. 2014 Apr;44(4):1093-8. doi: 10.1002/eji.201343529. Epub 2014 Jan 20.


Absent bactericidal activity of mouse serum against invasive African nontyphoidal Salmonella results from impaired complement function but not a lack of antibody.

Siggins MK, Cunningham AF, Marshall JL, Chamberlain JL, Henderson IR, MacLennan CA.

J Immunol. 2011 Feb 15;186(4):2365-71. doi: 10.4049/jimmunol.1000284. Epub 2011 Jan 7. Erratum in: J Immunol. 2011 Apr 1;186(7):4527.

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