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Items: 1 to 50 of 164

1.

Superoxide and NADPH oxidase do not modulate skin blood flow in older exercising adults with and without type 2 diabetes.

McGarr GW, Fujii N, McNeely BD, Hatam K, Nishiyasu T, Sigal RJ, Boulay P, Kenny GP.

Microvasc Res. 2019 Jun 11:103886. doi: 10.1016/j.mvr.2019.103886. [Epub ahead of print]

PMID:
31199960
2.

PERL in Diabetes Study: A Randomized Double-Blinded Trial of Allopurinol-Rationale, Design, and Baseline Data.

Afkarian M, Polsky S, Parsa A, Aronson R, Caramori ML, Cherney DZ, Crandall JP, de Boer IH, Elliott TG, Galecki AT, Goldfine AB, Haw JS, Hirsch IB, Karger AB, Lingvay I, Maahs DM, McGill JB, Molitch ME, Perkins BA, Pop-Busui R, Pragnell M, Rosas SE, Rossing P, Senior P, Sigal RJ, Spino C, Tuttle KR, Umpierrez GE, Wallia A, Weinstock RS, Wu C, Mauer M, Doria A; PERL Study Group.

Diabetes Care. 2019 Jun 11. pii: dc190342. doi: 10.2337/dc19-0342. [Epub ahead of print]

PMID:
31186299
3.

Interindividual variability and individual responses to exercise training in adolescents with obesity.

Walsh JJ, Bonafiglia JT, Goldfield GS, Sigal RJ, Kenny GP, Doucette S, Hadjiyannakis S, Alberga AS, Prud'homme D, Gurd BJ.

Appl Physiol Nutr Metab. 2019 May 23. doi: 10.1139/apnm-2019-0088. [Epub ahead of print]

PMID:
31121100
4.

Minimal effect of walking before dinner on glycemic responses in type 2 diabetes: outcomes from the multi-site E-PAraDiGM study.

Rees JL, Chang CR, François ME, Marcotte-Chénard A, Fontvieille A, Klaprat ND, Dyck RA, Funk DR, Snydmiller G, Bastell K, Godkin FE, Dubé MC, Riesco E, McGavock JM, Yardley JE, Sigal RJ, Gibala MJ, Weisnagel SJ, Prado CM, Jung M, Manders R, Lee T, Singer J, Boulé NG, Little JP.

Acta Diabetol. 2019 Jul;56(7):755-765. doi: 10.1007/s00592-019-01358-x. Epub 2019 May 15.

PMID:
31093764
5.

Impaired whole-body heat loss in type 1 diabetes during exercise in the heat: a cause for concern?

Notley SR, Poirier MP, Yardley JE, Sigal RJ, Kenny GP.

Diabetologia. 2019 Jun;62(6):1087-1089. doi: 10.1007/s00125-019-4858-5. Epub 2019 Apr 2. No abstract available.

PMID:
30941449
6.

Clinical Utility of Pre-Exercise Stress Testing in People With Diabetes.

Armstrong MJ, Rabi DM, Southern DA, Nanji A, Ghali WA, Sigal RJ.

Can J Cardiol. 2019 Feb;35(2):185-192. doi: 10.1016/j.cjca.2018.11.007. Epub 2018 Nov 20.

PMID:
30760425
7.

Local arginase inhibition does not modulate cutaneous vasodilation or sweating in young and older men during exercise.

Meade RD, Fujii N, McGarr GW, Alexander LM, Boulay P, Sigal RJ, Kenny GP.

J Appl Physiol (1985). 2019 Apr 1;126(4):1129-1137. doi: 10.1152/japplphysiol.00657.2018. Epub 2019 Jan 17.

PMID:
30653418
8.

Preliminary efficacy and feasibility of referral to exercise specialists, psychologists and provision of a technology-based behavior change support package to promote physical activity in school teachers 'at risk' of, or diagnosed with, type 2 diabetes: The 'SMART Health' Pilot Study Protocol.

Murphy ML, Lubans DR, Cohen KE, Robards SL, Wilczynska M, Kennedy SG, James EL, Brown WJ, Courneya KS, Sigal RJ, Plotnikoff RC.

Contemp Clin Trials. 2019 Mar;78:53-62. doi: 10.1016/j.cct.2019.01.007. Epub 2019 Jan 11.

PMID:
30639752
9.

Ageing attenuates muscarinic-mediated sweating differently in men and women with no effect on nicotinic-mediated sweating.

Fujii N, McGarr GW, Nishiyasu T, Sigal RJ, Boulay P, Kenny GP.

Exp Dermatol. 2019 Jan 10. doi: 10.1111/exd.13878. [Epub ahead of print]

PMID:
30629762
10.

Interactive effects of age and hydration state on human thermoregulatory function during exercise in hot-dry conditions.

Meade RD, Notley SR, D'Souza AW, Dervis S, Boulay P, Sigal RJ, Kenny GP.

Acta Physiol (Oxf). 2019 May;226(1):e13226. doi: 10.1111/apha.13226. Epub 2018 Dec 16.

PMID:
30480873
11.

Corrigendum to "Effects of aerobic training, resistance training, or both on brain-derived neurotrophic factor in adolescents with obesity: The hearty randomized controlled trial" Physiology & Behavior, Volume 191, 1 July 2018, Pages 138-145.

Goldfield GS, Kenny GP, Prud'homme D, Holcik M, Alberga AS, Fahnestock M, Cameron JD, Doucette S, Hadjiyannakis S, Tulloch H, Tremblay MS, Walsh J, Guerin E, Gunnell KE, D'Angiulli A, Sigal RJ.

Physiol Behav. 2019 Jan 1;198:161. doi: 10.1016/j.physbeh.2018.06.019. Epub 2018 Jun 30. No abstract available.

PMID:
30428994
12.

Changes in the Brain-Derived Neurotrophic Factor Are Associated with Improvements in Diabetes Risk Factors after Exercise Training in Adolescents with Obesity: The HEARTY Randomized Controlled Trial.

Walsh JJ, D'Angiulli A, Cameron JD, Sigal RJ, Kenny GP, Holcik M, Doucette S, Alberga AS, Prud'homme D, Hadjiyannakis S, Gunnell K, Goldfield GS.

Neural Plast. 2018 Sep 30;2018:7169583. doi: 10.1155/2018/7169583. eCollection 2018.

13.

Long-Term Effects of Intensive Glycemic and Blood Pressure Control and Fenofibrate Use on Kidney Outcomes.

Mottl AK, Buse JB, Ismail-Beigi F, Sigal RJ, Pedley CF, Papademetriou V, Simmons DL, Katz L, Mychaleckyj JC, Craven TE.

Clin J Am Soc Nephrol. 2018 Nov 7;13(11):1693-1702. doi: 10.2215/CJN.06200518. Epub 2018 Oct 25.

PMID:
30361335
14.

Genetic Tools for Coronary Risk Assessment in Type 2 Diabetes: A Cohort Study From the ACCORD Clinical Trial.

Morieri ML, Gao H, Pigeyre M, Shah HS, Sjaarda J, Mendonca C, Hastings T, Buranasupkajorn P, Motsinger-Reif AA, Rotroff DM, Sigal RJ, Marcovina SM, Kraft P, Buse JB, Wagner MJ, Gerstein HC, Mychaleckyj JC, Parè G, Doria A.

Diabetes Care. 2018 Nov;41(11):2404-2413. doi: 10.2337/dc18-0709. Epub 2018 Sep 27.

PMID:
30262460
15.

Role of exercise training in polycystic ovary syndrome: a systematic review and meta-analysis.

Benham JL, Yamamoto JM, Friedenreich CM, Rabi DM, Sigal RJ.

Clin Obes. 2018 Aug;8(4):275-284. doi: 10.1111/cob.12258. Epub 2018 Jun 12. Review.

PMID:
29896935
16.

Aging attenuates adenosine triphosphate-induced, but not muscarinic and nicotinic, cutaneous vasodilation in men.

Fujii N, Nishiyasu T, Sigal RJ, Boulay P, McGarr GW, Kenny GP.

Microcirculation. 2018 Jul;25(5):e12462. doi: 10.1111/micc.12462. Epub 2018 Jun 19.

PMID:
29846993
17.

Screening criteria for increased susceptibility to heat stress during work or leisure in hot environments in healthy individuals aged 31-70 years.

Flouris AD, McGinn R, Poirier MP, Louie JC, Ioannou LG, Tsoutsoubi L, Sigal RJ, Boulay P, Hardcastle SG, Kenny GP.

Temperature (Austin). 2017 Dec 18;5(1):86-99. doi: 10.1080/23328940.2017.1381800. eCollection 2018.

18.

Effects of aerobic training, resistance training, or both on brain-derived neurotrophic factor in adolescents with obesity: The hearty randomized controlled trial.

Goldfield GS, Kenny GP, Prud'homme D, Holcik M, Alberga AS, Fahnestock M, Cameron JD, Doucette S, Hadjiyannakis S, Tulloch H, Tremblay MS, Walsh J, Guerin E, Gunnell KE, D'Angiulli A, Sigal RJ.

Physiol Behav. 2018 Jul 1;191:138-145. doi: 10.1016/j.physbeh.2018.04.026. Epub 2018 Apr 19. Erratum in: Physiol Behav. 2019 Jan 1;198:161.

PMID:
29679660
19.

Physical Activity and Diabetes.

Diabetes Canada Clinical Practice Guidelines Expert Committee, Sigal RJ, Armstrong MJ, Bacon SL, Boulé NG, Dasgupta K, Kenny GP, Riddell MC.

Can J Diabetes. 2018 Apr;42 Suppl 1:S54-S63. doi: 10.1016/j.jcjd.2017.10.008. No abstract available.

PMID:
29650112
20.

Effect of P2 receptor blockade on cutaneous vasodilation during rest and exercise in the heat in young men.

Fujii N, Meade RD, Louie JC, Akbari P, Boulay P, Sigal RJ, Kenny GP.

Appl Physiol Nutr Metab. 2018 Mar;43(3):312-315. doi: 10.1139/apnm-2017-0700. Epub 2017 Dec 22.

PMID:
29272631
21.

Type 2 diabetes specifically attenuates purinergic skin vasodilatation without affecting muscarinic and nicotinic skin vasodilatation and sweating.

Fujii N, Meade RD, McNeely BD, Nishiyasu T, Sigal RJ, Kenny GP.

Exp Physiol. 2018 Feb 1;103(2):212-221. doi: 10.1113/EP086694. Epub 2018 Jan 10.

PMID:
29210478
22.

Modulation of GLP-1 Levels by a Genetic Variant That Regulates the Cardiovascular Effects of Intensive Glycemic Control in ACCORD.

Shah HS, Morieri ML, Marcovina SM, Sigal RJ, Gerstein HC, Wagner MJ, Motsinger-Reif AA, Buse JB, Kraft P, Mychaleckyj JC, Doria A.

Diabetes Care. 2018 Feb;41(2):348-355. doi: 10.2337/dc17-1638. Epub 2017 Nov 28.

23.

Oxidative stress does not influence local sweat rate during high-intensity exercise.

Meade RD, Fujii N, Poirier MP, Boulay P, Sigal RJ, Kenny GP.

Exp Physiol. 2018 Feb 1;103(2):172-178. doi: 10.1113/EP086746. Epub 2017 Dec 20.

PMID:
29152797
24.

Aging Impairs Whole-Body Heat Loss in Women under Both Dry and Humid Heat Stress.

Notley SR, Poirier MP, Hardcastle SG, Flouris AD, Boulay P, Sigal RJ, Kenny GP.

Med Sci Sports Exerc. 2017 Nov;49(11):2324-2332. doi: 10.1249/MSS.0000000000001342.

PMID:
29045327
25.

Depressive symptoms, perceived stress, self-efficacy, and outcome expectations: Predict fitness among adolescents with obesity.

Tulloch H, Heenan A, Sweet S, Goldfield GS, Kenny GP, Alberga AS, Sigal RJ.

J Health Psychol. 2017 Oct 1:1359105317734039. doi: 10.1177/1359105317734039. [Epub ahead of print]

PMID:
28980479
26.

Fluid replacement modulates oxidative stress- but not nitric oxide-mediated cutaneous vasodilation and sweating during prolonged exercise in the heat.

McNeely BD, Meade RD, Fujii N, Seely AJE, Sigal RJ, Kenny GP.

Am J Physiol Regul Integr Comp Physiol. 2017 Dec 1;313(6):R730-R739. doi: 10.1152/ajpregu.00284.2017. Epub 2017 Sep 20.

27.

Increasing age is a major risk factor for susceptibility to heat stress during physical activity.

McGinn R, Poirier MP, Louie JC, Sigal RJ, Boulay P, Flouris AD, Kenny GP.

Appl Physiol Nutr Metab. 2017 Nov;42(11):1232-1235. doi: 10.1139/apnm-2017-0322. Epub 2017 Aug 24.

28.

The recommended Threshold Limit Values for heat exposure fail to maintain body core temperature within safe limits in older working adults.

Lamarche DT, Meade RD, D'Souza AW, Flouris AD, Hardcastle SG, Sigal RJ, Boulay P, Kenny GP.

J Occup Environ Hyg. 2017 Sep;14(9):703-711. doi: 10.1080/15459624.2017.1321844.

PMID:
28609164
29.

Increased left ventricular extracellular volume and enhanced twist function in type 1 diabetic individuals.

Vasanji Z, Sigal RJ, Eves ND, Isaac DL, Friedrich MG, Chow K, Thompson RB.

J Appl Physiol (1985). 2017 Aug 1;123(2):394-401. doi: 10.1152/japplphysiol.00012.2017. Epub 2017 May 18.

30.

No effect of ascorbate on cutaneous vasodilation and sweating in older men and those with type 2 diabetes exercising in the heat.

Fujii N, Meade RD, Akbari P, Louie JC, Alexander LM, Boulay P, Sigal RJ, Kenny GP.

Physiol Rep. 2017 Apr;5(7). pii: e13238. doi: 10.14814/phy2.13238.

31.

Hyperthermia and cardiovascular strain during an extreme heat exposure in young versus older adults.

Kenny GP, Poirier MP, Metsios GS, Boulay P, Dervis S, Friesen BJ, Malcolm J, Sigal RJ, Seely AJ, Flouris AD.

Temperature (Austin). 2016 Aug 31;4(1):79-88. doi: 10.1080/23328940.2016.1230171. eCollection 2017.

32.

Cardiometabolic risk factors in type 2 diabetes with high fat and low muscle mass: At baseline and in response to exercise.

Terada T, Boulé NG, Forhan M, Prado CM, Kenny GP, Prud'homme D, Ito E, Sigal RJ.

Obesity (Silver Spring). 2017 May;25(5):881-891. doi: 10.1002/oby.21808. Epub 2017 Mar 20.

33.

Effects of aerobic or resistance training or both on health-related quality of life in youth with obesity: the HEARTY Trial.

Goldfield GS, Kenny GP, Alberga AS, Tulloch HE, Doucette S, Cameron JD, Sigal RJ.

Appl Physiol Nutr Metab. 2017 Apr;42(4):361-370. doi: 10.1139/apnm-2016-0386. Epub 2016 Dec 9.

PMID:
28177739
34.

Physical Activity/Exercise and Diabetes: A Position Statement of the American Diabetes Association.

Colberg SR, Sigal RJ, Yardley JE, Riddell MC, Dunstan DW, Dempsey PC, Horton ES, Castorino K, Tate DF.

Diabetes Care. 2016 Nov;39(11):2065-2079. Review. No abstract available.

PMID:
27926890
35.

Does exercise training affect resting metabolic rate in adolescents with obesity?

Alberga AS, Prud'homme D, Sigal RJ, Goldfield GS, Hadjiyannakis S, Gougeon R, Phillips P, Malcolm J, Wells GA, Doucette S, Ma J, Kenny GP.

Appl Physiol Nutr Metab. 2017 Jan;42(1):15-22. doi: 10.1139/apnm-2016-0244. Epub 2016 Aug 22.

PMID:
27923279
36.

Type 1 diabetes modulates cyclooxygenase- and nitric oxide-dependent mechanisms governing sweating but not cutaneous vasodilation during exercise in the heat.

Fujii N, Dervis S, Sigal RJ, Kenny GP.

Am J Physiol Regul Integr Comp Physiol. 2016 Dec 1;311(6):R1076-R1084. doi: 10.1152/ajpregu.00376.2016. Epub 2016 Oct 12.

37.

The mediating role of energy intake on the relationship between screen time behaviour and body mass index in adolescents with obesity: The HEARTY study.

Cameron JD, Maras D, Sigal RJ, Kenny GP, Borghese MM, Chaput JP, Alberga AS, Goldfield GS.

Appetite. 2016 Dec 1;107:437-444. doi: 10.1016/j.appet.2016.08.101. Epub 2016 Aug 18.

PMID:
27545672
38.

Genetic Predictors of Cardiovascular Mortality During Intensive Glycemic Control in Type 2 Diabetes: Findings From the ACCORD Clinical Trial.

Shah HS, Gao H, Morieri ML, Skupien J, Marvel S, Paré G, Mannino GC, Buranasupkajorn P, Mendonca C, Hastings T, Marcovina SM, Sigal RJ, Gerstein HC, Wagner MJ, Motsinger-Reif AA, Buse JB, Kraft P, Mychaleckyj JC, Doria A.

Diabetes Care. 2016 Nov;39(11):1915-1924. Epub 2016 Aug 15.

39.

Heart rate variability during high heat stress: a comparison between young and older adults with and without Type 2 diabetes.

Carrillo AE, Flouris AD, Herry CL, Poirier MP, Boulay P, Dervis S, Friesen BJ, Malcolm J, Sigal RJ, Seely AJE, Kenny GP.

Am J Physiol Regul Integr Comp Physiol. 2016 Oct 1;311(4):R669-R675. doi: 10.1152/ajpregu.00176.2016. Epub 2016 Aug 10.

40.

The OPTIMIZE trial: Rationale and design of a randomized controlled trial of motivational enhancement therapy to improve adherence to statin medication.

Rash JA, Lavoie KL, Sigal RJ, Campbell DJ, Manns BJ, Tonelli M, Campbell TS.

Contemp Clin Trials. 2016 Jul;49:47-56. doi: 10.1016/j.cct.2016.06.001. Epub 2016 Jun 6.

PMID:
27282119
41.

Body temperature regulation in diabetes.

Kenny GP, Sigal RJ, McGinn R.

Temperature (Austin). 2016 Jan 4;3(1):119-45. doi: 10.1080/23328940.2015.1131506. eCollection 2016 Jan-Mar. Review.

42.

Body composition and energy intake - skeletal muscle mass is the strongest predictor of food intake in obese adolescents: The HEARTY trial.

Cameron JD, Sigal RJ, Kenny GP, Alberga AS, Prud'homme D, Phillips P, Doucette S, Goldfield G.

Appl Physiol Nutr Metab. 2016 Jun;41(6):611-7. doi: 10.1139/apnm-2015-0479. Epub 2016 Feb 8.

PMID:
27111402
43.

Cutaneous vascular and sweating responses to intradermal administration of prostaglandin E1 and E2 in young and older adults: a role for nitric oxide?

Fujii N, Singh MS, Halili L, Boulay P, Sigal RJ, Kenny GP.

Am J Physiol Regul Integr Comp Physiol. 2016 Jun 1;310(11):R1064-72. doi: 10.1152/ajpregu.00538.2015. Epub 2016 Apr 13.

44.

Screen time is associated with depressive symptomatology among obese adolescents: a HEARTY study.

Goldfield GS, Murray M, Maras D, Wilson AL, Phillips P, Kenny GP, Hadjiyannakis S, Alberga A, Cameron JD, Tulluch H, Sigal RJ.

Eur J Pediatr. 2016 Jul;175(7):909-19. doi: 10.1007/s00431-016-2720-z. Epub 2016 Apr 13.

PMID:
27075014
45.

Cutaneous blood flow during intradermal NO administration in young and older adults: roles for calcium-activated potassium channels and cyclooxygenase?

Fujii N, Meade RD, Minson CT, Brunt VE, Boulay P, Sigal RJ, Kenny GP.

Am J Physiol Regul Integr Comp Physiol. 2016 Jun 1;310(11):R1081-7. doi: 10.1152/ajpregu.00041.2016. Epub 2016 Apr 6.

46.

Effects of aerobic training, resistance training, or both on cardiorespiratory and musculoskeletal fitness in adolescents with obesity: the HEARTY trial.

Alberga AS, Prud'homme D, Sigal RJ, Goldfield GS, Hadjiyannakis S, Phillips P, Malcolm J, Ma J, Doucette S, Gougeon R, Wells GA, Kenny GP.

Appl Physiol Nutr Metab. 2016 Mar;41(3):255-65. doi: 10.1139/apnm-2015-0413. Epub 2015 Nov 9.

PMID:
26881317
47.

Exercise as Medicine: Key Concepts in Discussing Physical Activity with Patients who have Type 2 Diabetes.

Armstrong MJ, Sigal RJ.

Can J Diabetes. 2015 Dec;39 Suppl 5:S129-33. Review.

PMID:
26653253
48.

Assessment of the MyWellness Key accelerometer in people with type 2 diabetes.

McGinley SK, Armstrong MJ, Khandwala F, Zanuso S, Sigal RJ.

Appl Physiol Nutr Metab. 2015 Nov;40(11):1193-8. doi: 10.1139/apnm-2015-0169. Epub 2015 Aug 10.

PMID:
26489052
49.

Insulin Dose and Cardiovascular Mortality in the ACCORD Trial.

Siraj ES, Rubin DJ, Riddle MC, Miller ME, Hsu FC, Ismail-Beigi F, Chen SH, Ambrosius WT, Thomas A, Bestermann W, Buse JB, Genuth S, Joyce C, Kovacs CS, O'Connor PJ, Sigal RJ, Solomon S; ACCORD Investigators.

Diabetes Care. 2015 Nov;38(11):2000-8. doi: 10.2337/dc15-0598. Epub 2015 Oct 13.

50.

Behavioral Programs for Type 2 Diabetes Mellitus: A Systematic Review and Network Meta-analysis.

Pillay J, Armstrong MJ, Butalia S, Donovan LE, Sigal RJ, Vandermeer B, Chordiya P, Dhakal S, Hartling L, Nuspl M, Featherstone R, Dryden DM.

Ann Intern Med. 2015 Dec 1;163(11):848-60. doi: 10.7326/M15-1400. Epub 2015 Sep 29. Review.

PMID:
26414227

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