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Items: 1 to 50 of 110

1.

Combining Desorption Electrospray Ionization Mass Spectrometry Imaging and Machine Learning for Molecular Recognition of Myocardial Infarction.

Margulis K, Zhou Z, Fang Q, Sievers RE, Lee RJ, Zare RN.

Anal Chem. 2018 Oct 16;90(20):12198-12206. doi: 10.1021/acs.analchem.8b03410. Epub 2018 Sep 25.

PMID:
30188683
2.

Injectable hyaluronic acid based microrods provide local micromechanical and biochemical cues to attenuate cardiac fibrosis after myocardial infarction.

Le LV, Mohindra P, Fang Q, Sievers RE, Mkrtschjan MA, Solis C, Safranek CW, Russell B, Lee RJ, Desai TA.

Biomaterials. 2018 Jul;169:11-21. doi: 10.1016/j.biomaterials.2018.03.042. Epub 2018 Mar 24.

3.

One Minute of Marijuana Secondhand Smoke Exposure Substantially Impairs Vascular Endothelial Function.

Wang X, Derakhshandeh R, Liu J, Narayan S, Nabavizadeh P, Le S, Danforth OM, Pinnamaneni K, Rodriguez HJ, Luu E, Sievers RE, Schick SF, Glantz SA, Springer ML.

J Am Heart Assoc. 2016 Jul 27;5(8). pii: e003858. doi: 10.1161/JAHA.116.003858.

4.

Treatment with hESC-Derived Myocardial Precursors Improves Cardiac Function after a Myocardial Infarction.

Ye J, Gaur M, Zhang Y, Sievers RE, Woods BJ, Aurigui J, Bernstein HS, Yeghiazarians Y.

PLoS One. 2015 Jul 31;10(7):e0131123. doi: 10.1371/journal.pone.0131123. eCollection 2015.

5.

Discrete microstructural cues for the attenuation of fibrosis following myocardial infarction.

Pinney JR, Du KT, Ayala P, Fang Q, Sievers RE, Chew P, Delrosario L, Lee RJ, Desai TA.

Biomaterials. 2014 Oct;35(31):8820-8828. doi: 10.1016/j.biomaterials.2014.07.005. Epub 2014 Jul 18.

6.

Brief exposure to secondhand smoke reversibly impairs endothelial vasodilatory function.

Pinnamaneni K, Sievers RE, Sharma R, Selchau AM, Gutierrez G, Nordsieck EJ, Su R, An S, Chen Q, Wang X, Derakhshandeh R, Aschbacher K, Heiss C, Glantz SA, Schick SF, Springer ML.

Nicotine Tob Res. 2014 May;16(5):584-90. doi: 10.1093/ntr/ntt189. Epub 2013 Dec 3.

7.

The effect of a peptide-modified thermo-reversible methylcellulose on wound healing and LV function in a chronic myocardial infarction rodent model.

Mihardja SS, Gonzales JA, Gao D, Sievers RE, Fang Q, Stillson CA, Yu J, Peng M, Lee RJ.

Biomaterials. 2013 Nov;34(35):8869-77. doi: 10.1016/j.biomaterials.2013.07.028. Epub 2013 Jul 26.

PMID:
23895998
8.

Pleiotrophin gene therapy for peripheral ischemia: evaluation of full-length and truncated gene variants.

Fang Q, Mok PY, Thomas AE, Haddad DJ, Saini SA, Clifford BT, Kapasi NK, Danforth OM, Usui M, Ye W, Luu E, Sharma R, Bartel MJ, Pathmanabhan JA, Ang AA, Sievers RE, Lee RJ, Springer ML.

PLoS One. 2013 Apr 22;8(4):e61413. doi: 10.1371/journal.pone.0061413. Print 2013.

9.

Pharmacological inhibition of S-nitrosoglutathione reductase improves endothelial vasodilatory function in rats in vivo.

Chen Q, Sievers RE, Varga M, Kharait S, Haddad DJ, Patton AK, Delany CS, Mutka SC, Blonder JP, Dubé GP, Rosenthal GJ, Springer ML.

J Appl Physiol (1985). 2013 Mar 15;114(6):752-60. doi: 10.1152/japplphysiol.01302.2012. Epub 2013 Jan 24.

10.

CD45-positive cells are not an essential component in cardiosphere formation.

Ye J, Boyle AJ, Shih H, Sievers RE, Wang ZE, Gormley M, Yeghiazarians Y.

Cell Tissue Res. 2013 Jan;351(1):201-5. doi: 10.1007/s00441-012-1511-8. Epub 2012 Oct 13.

PMID:
23064904
11.

Advanced Donor Age Impairs Bone Marrow Cell Therapeutic Efficacy for Cardiac Disease.

Wang X, Takagawa J, Haddad DJ, Pinnamaneni K, Zhang Y, Sievers RE, Grossman W, Yeghiazarians Y, Springer ML.

J Tissue Sci Eng. 2011 Nov 18;S3. pii: 002.

12.

Fractionation of mouse bone-marrow cells limits functional efficacy in non-reperfused mouse model of acute myocardial infarction.

Koskenvuo JW, Sievers RE, Zhang Y, Angeli FS, Lee B, Shih H, Ye J, Boyle AJ, Yeghiazarians Y.

Ann Med. 2012 Dec;44(8):829-35. doi: 10.3109/07853890.2012.672026. Epub 2012 Apr 12.

PMID:
22494088
13.

Sca-1+ cardiosphere-derived cells are enriched for Isl1-expressing cardiac precursors and improve cardiac function after myocardial injury.

Ye J, Boyle A, Shih H, Sievers RE, Zhang Y, Prasad M, Su H, Zhou Y, Grossman W, Bernstein HS, Yeghiazarians Y.

PLoS One. 2012;7(1):e30329. doi: 10.1371/journal.pone.0030329. Epub 2012 Jan 17.

14.

Myocardial improvement with human embryonic stem cell-derived cardiomyocytes enriched by p38MAPK inhibition.

Yeghiazarians Y, Gaur M, Zhang Y, Sievers RE, Ritner C, Prasad M, Boyle A, Bernstein HS.

Cytotherapy. 2012 Feb;14(2):223-31. doi: 10.3109/14653249.2011.623690. Epub 2011 Oct 31.

15.

Donor myocardial infarction impairs the therapeutic potential of bone marrow cells by an interleukin-1-mediated inflammatory response.

Wang X, Takagawa J, Lam VC, Haddad DJ, Tobler DL, Mok PY, Zhang Y, Clifford BT, Pinnamaneni K, Saini SA, Su R, Bartel MJ, Sievers RE, Carbone L, Kogan S, Yeghiazarians Y, Hermiston M, Springer ML.

Sci Transl Med. 2011 Sep 14;3(100):100ra90. doi: 10.1126/scitranslmed.3002814.

16.

Treatment of pulmonary arterial hypertension with circulating angiogenic cells.

Mirsky R, Jahn S, Koskenvuo JW, Sievers RE, Yim SM, Ritner C, Bernstein HS, Angeli FS, Boyle AJ, De Marco T, Yeghiazarians Y.

Am J Physiol Lung Cell Mol Physiol. 2011 Jul;301(1):L12-9. doi: 10.1152/ajplung.00215.2010. Epub 2011 Mar 11.

17.

Successful respiratory immunization with dry powder live-attenuated measles virus vaccine in rhesus macaques.

Lin WH, Griffin DE, Rota PA, Papania M, Cape SP, Bennett D, Quinn B, Sievers RE, Shermer C, Powell K, Adams RJ, Godin S, Winston S.

Proc Natl Acad Sci U S A. 2011 Feb 15;108(7):2987-92. doi: 10.1073/pnas.1017334108. Epub 2011 Jan 31.

18.

Dry powder measles vaccine: particle deposition, virus replication, and immune response in cotton rats following inhalation.

Kisich KO, Higgins MP, Park I, Cape SP, Lindsay L, Bennett DJ, Winston S, Searles J, Sievers RE.

Vaccine. 2011 Jan 29;29(5):905-12. doi: 10.1016/j.vaccine.2010.10.020. Epub 2010 Oct 23.

PMID:
20974303
19.

Timing of bone marrow cell therapy is more important than repeated injections after myocardial infarction.

Zhang Y, Sievers RE, Prasad M, Mirsky R, Shih H, Wong ML, Angeli FS, Ye J, Takagawa J, Koskenvuo JW, Springer ML, Grossman W, Boyle AJ, Yeghiazarians Y.

Cardiovasc Pathol. 2011 Jul-Aug;20(4):204-12. doi: 10.1016/j.carpath.2010.06.007. Epub 2010 Jul 29.

PMID:
20667749
20.

The use of human mesenchymal stem cells encapsulated in RGD modified alginate microspheres in the repair of myocardial infarction in the rat.

Yu J, Du KT, Fang Q, Gu Y, Mihardja SS, Sievers RE, Wu JC, Lee RJ.

Biomaterials. 2010 Sep;31(27):7012-20. doi: 10.1016/j.biomaterials.2010.05.078. Epub 2010 Jun 20.

PMID:
20566215
21.

Targeted in vivo extracellular matrix formation promotes neovascularization in a rodent model of myocardial infarction.

Mihardja SS, Gao D, Sievers RE, Fang Q, Feng J, Wang J, Vanbrocklin HF, Larrick JW, Huang M, Dae M, Lee RJ.

PLoS One. 2010 Apr 28;5(4):e10384. doi: 10.1371/journal.pone.0010384.

22.

Bone marrow-derived mesenchymal stem cells in fibrin augment angiogenesis in the chronically infarcted myocardium.

Huang NF, Lam A, Fang Q, Sievers RE, Li S, Lee RJ.

Regen Med. 2009 Jul;4(4):527-38. doi: 10.2217/rme.09.32.

23.

Injection of bone marrow cell extract into infarcted hearts results in functional improvement comparable to intact cell therapy.

Yeghiazarians Y, Zhang Y, Prasad M, Shih H, Saini SA, Takagawa J, Sievers RE, Wong ML, Kapasi NK, Mirsky R, Koskenvuo J, Minasi P, Ye J, Viswanathan MN, Angeli FS, Boyle AJ, Springer ML, Grossman W.

Mol Ther. 2009 Jul;17(7):1250-6. doi: 10.1038/mt.2009.85. Epub 2009 Apr 21.

24.

Restoration of left ventricular geometry and improvement of left ventricular function in a rodent model of chronic ischemic cardiomyopathy.

Yu J, Christman KL, Chin E, Sievers RE, Saeed M, Lee RJ.

J Thorac Cardiovasc Surg. 2009 Jan;137(1):180-7. doi: 10.1016/j.jtcvs.2008.08.036.

25.

The effect of injected RGD modified alginate on angiogenesis and left ventricular function in a chronic rat infarct model.

Yu J, Gu Y, Du KT, Mihardja S, Sievers RE, Lee RJ.

Biomaterials. 2009 Feb;30(5):751-6. doi: 10.1016/j.biomaterials.2008.09.059. Epub 2008 Nov 17.

PMID:
19010528
26.

The effect of polypyrrole on arteriogenesis in an acute rat infarct model.

Mihardja SS, Sievers RE, Lee RJ.

Biomaterials. 2008 Nov;29(31):4205-10. doi: 10.1016/j.biomaterials.2008.07.021. Epub 2008 Aug 3.

27.

Preparation of active proteins, vaccines and pharmaceuticals as fine powders using supercritical or near-critical fluids.

Cape SP, Villa JA, Huang ET, Yang TH, Carpenter JF, Sievers RE.

Pharm Res. 2008 Sep;25(9):1967-90. doi: 10.1007/s11095-008-9575-6. Epub 2008 Jun 26. Review.

28.

Stabilizing formulations for inhalable powders of live-attenuated measles virus vaccine.

Burger JL, Cape SP, Braun CS, McAdams DH, Best JA, Bhagwat P, Pathak P, Rebits LG, Sievers RE.

J Aerosol Med Pulm Drug Deliv. 2008 Mar;21(1):25-34. doi: 10.1089/jamp.2007.0658.

PMID:
18518829
29.

Reevaluation of the role of VEGF-B suggests a restricted role in the revascularization of the ischemic myocardium.

Li X, Tjwa M, Van Hove I, Enholm B, Neven E, Paavonen K, Jeltsch M, Juan TD, Sievers RE, Chorianopoulos E, Wada H, Vanwildemeersch M, Noel A, Foidart JM, Springer ML, von Degenfeld G, Dewerchin M, Blau HM, Alitalo K, Eriksson U, Carmeliet P, Moons L.

Arterioscler Thromb Vasc Biol. 2008 Sep;28(9):1614-20. doi: 10.1161/ATVBAHA.107.158725. Epub 2008 May 29.

30.

Stabilization of measles virus for vaccine formulation.

Kissmann J, Ausar SF, Rudolph A, Braun C, Cape SP, Sievers RE, Federspiel MJ, Joshi SB, Middaugh CR.

Hum Vaccin. 2008 Sep-Oct;4(5):350-9. Epub 2008 Sep 7.

PMID:
18382143
31.

In vivo measurement of flow-mediated vasodilation in living rats using high-resolution ultrasound.

Heiss C, Sievers RE, Amabile N, Momma TY, Chen Q, Natarajan S, Yeghiazarians Y, Springer ML.

Am J Physiol Heart Circ Physiol. 2008 Feb;294(2):H1086-93. Epub 2007 Nov 30.

32.

A rodent model of myocardial infarction for testing the efficacy of cells and polymers for myocardial reconstruction.

Huang NF, Sievers RE, Park JS, Fang Q, Li S, Lee RJ.

Nat Protoc. 2006;1(3):1596-609.

PMID:
17406452
33.

Myocardial infarct size measurement in the mouse chronic infarction model: comparison of area- and length-based approaches.

Takagawa J, Zhang Y, Wong ML, Sievers RE, Kapasi NK, Wang Y, Yeghiazarians Y, Lee RJ, Grossman W, Springer ML.

J Appl Physiol (1985). 2007 Jun;102(6):2104-11. Epub 2007 Mar 8.

34.

Antibody targeting of stem cells to infarcted myocardium.

Lee RJ, Fang Q, Davol PA, Gu Y, Sievers RE, Grabert RC, Gall JM, Tsang E, Yee MS, Fok H, Huang NF, Padbury JF, Larrick JW, Lum LG.

Stem Cells. 2007 Mar;25(3):712-7. Epub 2006 Nov 30.

35.

Validation of the wall motion score and myocardial performance indexes as novel techniques to assess cardiac function in mice after myocardial infarction.

Zhang Y, Takagawa J, Sievers RE, Khan MF, Viswanathan MN, Springer ML, Foster E, Yeghiazarians Y.

Am J Physiol Heart Circ Physiol. 2007 Feb;292(2):H1187-92. Epub 2006 Oct 6.

36.

Pleiotrophin induces formation of functional neovasculature in vivo.

Christman KL, Fang Q, Kim AJ, Sievers RE, Fok HH, Candia AF, Colley KJ, Herradon G, Ezquerra L, Deuel TF, Lee RJ.

Biochem Biophys Res Commun. 2005 Jul 15;332(4):1146-52.

PMID:
15949466
37.

Closed-chest cell injections into mouse myocardium guided by high-resolution echocardiography.

Springer ML, Sievers RE, Viswanathan MN, Yee MS, Foster E, Grossman W, Yeghiazarians Y.

Am J Physiol Heart Circ Physiol. 2005 Sep;289(3):H1307-14. Epub 2005 May 20.

38.

Enhanced neovasculature formation in ischemic myocardium following delivery of pleiotrophin plasmid in a biopolymer.

Christman KL, Fang Q, Yee MS, Johnson KR, Sievers RE, Lee RJ.

Biomaterials. 2005 Apr;26(10):1139-44.

PMID:
15451633
39.

Injectable fibrin scaffold improves cell transplant survival, reduces infarct expansion, and induces neovasculature formation in ischemic myocardium.

Christman KL, Vardanian AJ, Fang Q, Sievers RE, Fok HH, Lee RJ.

J Am Coll Cardiol. 2004 Aug 4;44(3):654-60.

40.

Fibrin glue alone and skeletal myoblasts in a fibrin scaffold preserve cardiac function after myocardial infarction.

Christman KL, Fok HH, Sievers RE, Fang Q, Lee RJ.

Tissue Eng. 2004 Mar-Apr;10(3-4):403-9.

PMID:
15165457
41.

New technique for measurement of left ventricular pressure in conscious mice.

Ishizaka S, Sievers RE, Zhu BQ, Rodrigo MC, Joho S, Foster E, Simpson PC, Grossman W.

Am J Physiol Heart Circ Physiol. 2004 Mar;286(3):H1208-15. Epub 2003 Oct 16.

42.

Second hand smoke stimulates tumor angiogenesis and growth.

Zhu BQ, Heeschen C, Sievers RE, Karliner JS, Parmley WW, Glantz SA, Cooke JP.

Cancer Cell. 2003 Sep;4(3):191-6.

43.

Pinhole single-photon emission computed tomography for myocardial perfusion imaging of mice.

Wu MC, Gao DW, Sievers RE, Lee RJ, Hasegawa BH, Dae MW.

J Am Coll Cardiol. 2003 Aug 6;42(3):576-82.

44.

Comparative effects of aspirin with ACE inhibitor or angiotensin receptor blocker on myocardial infarction and vascular function.

Zhu BQ, Sievers RE, Browne AE, Lee RJ, Chatterjee K, Grossman W, Karliner JS, Parmley WW.

J Renin Angiotensin Aldosterone Syst. 2003 Mar;4(1):31-7.

PMID:
12692751
45.

The renin-angiotensin system does not contribute to the endothelial dysfunction and increased infarct size in rats exposed to second hand smoke.

Zhu BQ, Sievers RE, Browne AE, Hillman RT, Chair K, Lee RJ, Chatterjee K, Glantz SA, Parmley WW.

J Renin Angiotensin Aldosterone Syst. 2002 Mar;3(1):54-60.

PMID:
11984749
46.

Effects of different durations of pretreatment with losartan on myocardial infarct size, endothelial function, and vascular endothelial growth factor.

Zhu B, Sun Y, Sievers RE, Browne AE, Lee RJ, Chatterjee K, Parmley WW.

J Renin Angiotensin Aldosterone Syst. 2001 Jun;2(2):129-33.

PMID:
11881112
47.

Secondhand tobacco smoke impairs rabbit pulmonary artery endothelium-dependent relaxation.

Hutchison SJ, Sievers RE, Zhu BQ, Sun YP, Stewart DJ, Parmley WW, Chatterjee K.

Chest. 2001 Dec;120(6):2004-12.

PMID:
11742935
48.

Nicotine does not influence arterial lipid deposits in rabbits exposed to second-hand smoke.

Sun YP, Zhu BQ, Browne AE, Sievers RE, Bekker JM, Chatterjee K, Parmley WW, Glantz SA.

Circulation. 2001 Aug 14;104(7):810-4.

PMID:
11502707
49.

Dry powders of stable protein formulations from aqueous solutions prepared using supercritical CO(2)-assisted aerosolization.

Sellers SP, Clark GS, Sievers RE, Carpenter JF.

J Pharm Sci. 2001 Jun;90(6):785-97.

PMID:
11357179
50.

Comparative effects of pretreatment with captopril and losartan on cardiovascular protection in a rat model of ischemia-reperfusion.

Zhu B, Sun Y, Sievers RE, Browne AE, Pulukurthy S, Sudhir K, Lee RJ, Chou TM, Chatterjee K, Parmley WW.

J Am Coll Cardiol. 2000 Mar 1;35(3):787-95.

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