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Items: 8


The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells.

Petschnigg J, Groisman B, Kotlyar M, Taipale M, Zheng Y, Kurat CF, Sayad A, Sierra JR, Mattiazzi Usaj M, Snider J, Nachman A, Krykbaeva I, Tsao MS, Moffat J, Pawson T, Lindquist S, Jurisica I, Stagljar I.

Nat Methods. 2014 May;11(5):585-92. doi: 10.1038/nmeth.2895. Epub 2014 Mar 23.


c-MET as a potential therapeutic target and biomarker in cancer.

Sierra JR, Tsao MS.

Ther Adv Med Oncol. 2011 Nov;3(1 Suppl):S21-35. doi: 10.1177/1758834011422557.


MET and KRAS gene amplification mediates acquired resistance to MET tyrosine kinase inhibitors.

Cepero V, Sierra JR, Corso S, Ghiso E, Casorzo L, Perera T, Comoglio PM, Giordano S.

Cancer Res. 2010 Oct 1;70(19):7580-90. doi: 10.1158/0008-5472.CAN-10-0436. Epub 2010 Sep 14.


Activation of HER family members in gastric carcinoma cells mediates resistance to MET inhibition.

Corso S, Ghiso E, Cepero V, Sierra JR, Migliore C, Bertotti A, Trusolino L, Comoglio PM, Giordano S.

Mol Cancer. 2010 May 26;9:121. doi: 10.1186/1476-4598-9-121.


Molecular mechanisms of acquired resistance to tyrosine kinase targeted therapy.

Sierra JR, Cepero V, Giordano S.

Mol Cancer. 2010 Apr 12;9:75. doi: 10.1186/1476-4598-9-75.


Tyrosine kinases as molecular targets to inhibit cancer progression and metastasis.

Cepero V, Sierra JR, Giordano S.

Curr Pharm Des. 2010;16(12):1396-409. Review.


Tumor angiogenesis and progression are enhanced by Sema4D produced by tumor-associated macrophages.

Sierra JR, Corso S, Caione L, Cepero V, Conrotto P, Cignetti A, Piacibello W, Kumanogoh A, Kikutani H, Comoglio PM, Tamagnone L, Giordano S.

J Exp Med. 2008 Jul 7;205(7):1673-85. doi: 10.1084/jem.20072602. Epub 2008 Jun 16.


Derivation of neurons with functional properties from adult limbal epithelium: implications in autologous cell therapy for photoreceptor degeneration.

Zhao X, Das AV, Bhattacharya S, Thoreson WB, Sierra JR, Mallya KB, Ahmad I.

Stem Cells. 2008 Apr;26(4):939-49. doi: 10.1634/stemcells.2007-0727. Epub 2008 Jan 17.

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