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Items: 32


High-energy external defibrillation and transcutaneous pacing during MRI: feasibility and safety.

Shusterman V, Hodgson-Zingman D, Thedens D, Zhu X, Hoffman S, Sieren JC, Morgan GM, Faranesh A, London B.

J Cardiovasc Magn Reson. 2019 Aug 5;21(1):47. doi: 10.1186/s12968-019-0558-z.


Assessment of nociception and related quality-of-life measures in a porcine model of neurofibromatosis type 1.

Khanna R, Moutal A, White KA, Chefdeville A, Negrao de Assis P, Cai S, Swier VJ, Bellampalli SS, Giunta MD, Darbro BW, Quelle DE, Sieren JC, Wallace MR, Rogers CS, Meyerholz DK, Weimer JM.

Pain. 2019 Jul 17. doi: 10.1097/j.pain.0000000000001648. [Epub ahead of print]


Machine learning approach for distinguishing malignant and benign lung nodules utilizing standardized perinodular parenchymal features from CT.

Uthoff J, Stephens MJ, Newell JD Jr, Hoffman EA, Larson J, Koehn N, De Stefano FA, Lusk CM, Wenzlaff AS, Watza D, Neslund-Dudas C, Carr LL, Lynch DA, Schwartz AG, Sieren JC.

Med Phys. 2019 Jul;46(7):3207-3216. doi: 10.1002/mp.13592. Epub 2019 Jun 7.


Post-imaging pulmonary nodule mathematical prediction models: are they clinically relevant?

Uthoff J, Koehn N, Larson J, Dilger SKN, Hammond E, Schwartz A, Mullan B, Sanchez R, Hoffman RM, Sieren JC; COPDGene Investigators.

Eur Radiol. 2019 Oct;29(10):5367-5377. doi: 10.1007/s00330-019-06168-x. Epub 2019 Apr 1.


Quantitative Imaging Markers of Lung Function in a Smoking Population Distinguish COPD Subgroups with Differential Lung Cancer Risk.

Lusk CM, Wenzlaff AS, Watza D, Sieren JC, Robinette N, Walworth G, Petrich M, Neslund-Dudas C, Flynn MJ, Song T, Spizarny D, Simoff MJ, Soubani AO, Gadgeel S, Schwartz AG.

Cancer Epidemiol Biomarkers Prev. 2019 Apr;28(4):724-730. doi: 10.1158/1055-9965.EPI-18-0886. Epub 2019 Jan 14.


Radiomic biomarkers informative of cancerous transformation in neurofibromatosis-1 plexiform tumors.

Uthoff J, De Stefano FA, Panzer K, Darbro BW, Sato TS, Khanna R, Quelle DE, Meyerholz DK, Weimer J, Sieren JC.

J Neuroradiol. 2019 May;46(3):179-185. doi: 10.1016/j.neurad.2018.05.006. Epub 2018 Jun 27.


Impact of advanced detector technology and iterative reconstruction on low-dose quantitative assessment of lung computed tomography density in a biological lung model.

Hammond E, Chan KS, Ames JC, Stoyles N, Sloan CM, Guo J, Newell JD Jr, Hoffman EA, Sieren JC.

Med Phys. 2018 Jun 21. doi: 10.1002/mp.13057. [Epub ahead of print]


A porcine model of neurofibromatosis type 1 that mimics the human disease.

White KA, Swier VJ, Cain JT, Kohlmeyer JL, Meyerholz DK, Tanas MR, Uthoff J, Hammond E, Li H, Rohret FA, Goeken A, Chan CH, Leidinger MR, Umesalma S, Wallace MR, Dodd RD, Panzer K, Tang AH, Darbro BW, Moutal A, Cai S, Li W, Bellampalli SS, Khanna R, Rogers CS, Sieren JC, Quelle DE, Weimer JM.

JCI Insight. 2018 Jun 21;3(12). pii: 120402. doi: 10.1172/jci.insight.120402. eCollection 2018 Jun 21.


Features of COPD as Predictors of LungĀ Cancer.

Carr LL, Jacobson S, Lynch DA, Foreman MG, Flenaugh EL, Hersh CP, Sciurba FC, Wilson DO, Sieren JC, Mulhall P, Kim V, Kinsey CM, Bowler RP.

Chest. 2018 Jun;153(6):1326-1335. doi: 10.1016/j.chest.2018.01.049. Epub 2018 Feb 13.


Immunohistochemical Markers for Prospective Studies in Neurofibromatosis-1 Porcine Models.

Meyerholz DK, Ofori-Amanfo GK, Leidinger MR, Goeken JA, Khanna R, Sieren JC, Darbro BW, Quelle DE, Weimer JM.

J Histochem Cytochem. 2017 Oct;65(10):607-618. doi: 10.1369/0022155417729357. Epub 2017 Aug 28.


Approaches to Evaluate Lung Inflammation in Translational Research.

Meyerholz DK, Sieren JC, Beck AP, Flaherty HA.

Vet Pathol. 2018 Jan;55(1):42-52. doi: 10.1177/0300985817726117. Epub 2017 Aug 16. Review.


Comparison of low- and ultralow-dose computed tomography protocols for quantitative lung and airway assessment.

Hammond E, Sloan C, Newell JD Jr, Sieren JP, Saylor M, Vidal C, Hogue S, De Stefano F, Sieren A, Hoffman EA, Sieren JC.

Med Phys. 2017 Sep;44(9):4747-4757. doi: 10.1002/mp.12436. Epub 2017 Aug 2.


Computed Tomography Measure of Lung at Risk and Lung Function Decline in Chronic Obstructive Pulmonary Disease.

Bhatt SP, Bodduluri S, Hoffman EA, Newell JD Jr, Sieren JC, Dransfield MT, Reinhardt JM; COPDGene Investigators.

Am J Respir Crit Care Med. 2017 Sep 1;196(5):569-576. doi: 10.1164/rccm.201701-0050OC.


Radiomics of Lung Nodules: A Multi-Institutional Study of Robustness and Agreement of Quantitative Imaging Features.

Kalpathy-Cramer J, Mamomov A, Zhao B, Lu L, Cherezov D, Napel S, Echegaray S, Rubin D, McNitt-Gray M, Lo P, Sieren JC, Uthoff J, Dilger SK, Driscoll B, Yeung I, Hadjiiski L, Cha K, Balagurunathan Y, Gillies R, Goldgof D.

Tomography. 2016 Dec;2(4):430-437. doi: 10.18383/j.tom.2016.00235.


Protein Kinase CĪ¶ Inhibitor Promotes Resolution of Bleomycin-Induced Acute Lung Injury.

Buonfiglio LG, Bagegni M, Borcherding JA, Sieren JC, Caraballo JC, Reger A, Zabner J, Li X, Comellas AP.

Am J Respir Cell Mol Biol. 2016 Dec;55(6):869-877.


CT-derived Biomechanical Metrics Improve Agreement Between Spirometry and Emphysema.

Bhatt SP, Bodduluri S, Newell JD, Hoffman EA, Sieren JC, Han MK, Dransfield MT, Reinhardt JM; COPDGene Investigators.

Acad Radiol. 2016 Oct;23(10):1255-63. doi: 10.1016/j.acra.2016.02.002. Epub 2016 Apr 4.


Improved pulmonary nodule classification utilizing quantitative lung parenchyma features.

Dilger SK, Uthoff J, Judisch A, Hammond E, Mott SL, Smith BJ, Newell JD Jr, Hoffman EA, Sieren JC.

J Med Imaging (Bellingham). 2015 Oct;2(4):041004. doi: 10.1117/1.JMI.2.4.041004. Epub 2015 Sep 1.


Computed Tomography and Magnetic Resonance Imaging for Longitudinal Characterization of Lung Structure Changes in a Yucatan Miniature Pig Silicosis Model.

Hammond E, Newell JD Jr, Dilger SK, Stoyles N, Morgan J, Sieren JP, Thedens DR, Hoffman EA, Meyerholz DK, Sieren JC.

Toxicol Pathol. 2016 Apr;44(3):373-81. doi: 10.1177/0192623315622303. Epub 2016 Feb 2.


Porcine cancer models for translational oncology.

Sieren JC, Quelle D, Meyerholz DK, Rogers CS.

Mol Cell Oncol. 2014 Nov 11;1(4):e969626. doi: 10.4161/23723548.2014.969626. eCollection 2014 Oct-Dec.


Comparison of spirometric thresholds in diagnosing smoking-related airflow obstruction: authors' response.

Bhatt SP, Washko GR, Dransfield MT, Sieren JC, Newell JD Jr, Hoffman EA.

Thorax. 2014 Dec;69(12):1147-8. doi: 10.1136/thoraxjnl-2014-206123. Epub 2014 Sep 9. No abstract available.


Development and translational imaging of a TP53 porcine tumorigenesis model.

Sieren JC, Meyerholz DK, Wang XJ, Davis BT, Newell JD Jr, Hammond E, Rohret JA, Rohret FA, Struzynski JT, Goeken JA, Naumann PW, Leidinger MR, Taghiyev A, Van Rheeden R, Hagen J, Darbro BW, Quelle DE, Rogers CS.

J Clin Invest. 2014 Sep;124(9):4052-66. doi: 10.1172/JCI75447. Epub 2014 Aug 8.


Disproportionate contribution of right middle lobe to emphysema and gas trapping on computed tomography.

Bhatt SP, Sieren JC, Newell JD Jr, Comellas AP, Hoffman EA.

PLoS One. 2014 Jul 23;9(7):e102807. doi: 10.1371/journal.pone.0102807. eCollection 2014.


Comparison of spirometric thresholds in diagnosing smoking-related airflow obstruction.

Bhatt SP, Sieren JC, Dransfield MT, Washko GR, Newell JD Jr, Stinson DS, Zamba GK, Hoffman EA; COPDGene Investigators.

Thorax. 2014 May;69(5):409-14. doi: 10.1136/thoraxjnl-2012-202810. Epub 2013 Mar 23.


Sinus hypoplasia precedes sinus infection in a porcine model of cystic fibrosis.

Chang EH, Pezzulo AA, Meyerholz DK, Potash AE, Wallen TJ, Reznikov LR, Sieren JC, Karp PH, Ernst S, Moninger TO, Gansemer ND, McCray PB Jr, Stoltz DA, Welsh MJ, Zabner J.

Laryngoscope. 2012 Sep;122(9):1898-905. doi: 10.1002/lary.23392. Epub 2012 Jun 18.


Mitochondrial Rac1 GTPase import and electron transfer from cytochrome c are required for pulmonary fibrosis.

Osborn-Heaford HL, Ryan AJ, Murthy S, Racila AM, He C, Sieren JC, Spitz DR, Carter AB.

J Biol Chem. 2012 Jan 27;287(5):3301-12. doi: 10.1074/jbc.M111.308387. Epub 2011 Dec 8.


Exploration of the volumetric composition of human lung cancer nodules in correlated histopathology and computed tomography.

Sieren JC, Smith AR, Thiesse J, Namati E, Hoffman EA, Kline JN, McLennan G.

Lung Cancer. 2011 Oct;74(1):61-8. doi: 10.1016/j.lungcan.2011.01.023. Epub 2011 Mar 2.


Recent technological and application developments in computed tomography and magnetic resonance imaging for improved pulmonary nodule detection and lung cancer staging.

Sieren JC, Ohno Y, Koyama H, Sugimura K, McLennan G.

J Magn Reson Imaging. 2010 Dec;32(6):1353-69. doi: 10.1002/jmri.22383. Review.


Longitudinal assessment of lung cancer progression in the mouse using in vivo micro-CT imaging.

Namati E, Thiesse J, Sieren JC, Ross A, Hoffman EA, McLennan G.

Med Phys. 2010 Sep;37(9):4793-805.


Dynamic regulation of cardiolipin by the lipid pump Atp8b1 determines the severity of lung injury in experimental pneumonia.

Ray NB, Durairaj L, Chen BB, McVerry BJ, Ryan AJ, Donahoe M, Waltenbaugh AK, O'Donnell CP, Henderson FC, Etscheidt CA, McCoy DM, Agassandian M, Hayes-Rowan EC, Coon TA, Butler PL, Gakhar L, Mathur SN, Sieren JC, Tyurina YY, Kagan VE, McLennan G, Mallampalli RK.

Nat Med. 2010 Oct;16(10):1120-1127. doi: 10.1038/nm.2213. Epub 2010 Sep 19.


Lung structure phenotype variation in inbred mouse strains revealed through in vivo micro-CT imaging.

Thiesse J, Namati E, Sieren JC, Smith AR, Reinhardt JM, Hoffman EA, McLennan G.

J Appl Physiol (1985). 2010 Dec;109(6):1960-8. doi: 10.1152/japplphysiol.01322.2009. Epub 2010 Jul 29.


An automated segmentation approach for highlighting the histological complexity of human lung cancer.

Sieren JC, Weydert J, Bell A, De Young B, Smith AR, Thiesse J, Namati E, McLennan G.

Ann Biomed Eng. 2010 Dec;38(12):3581-91. doi: 10.1007/s10439-010-0103-6. Epub 2010 Jun 23.


A process model for direct correlation between computed tomography and histopathology application in lung cancer.

Sieren JC, Weydert J, Namati E, Thiesse J, Sieren JP, Reinhardt JM, Hoffman EA, McLennan G.

Acad Radiol. 2010 Feb;17(2):169-80. doi: 10.1016/j.acra.2009.09.006.

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