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Items: 15

1.

Mouse Tmem135 mutation reveals a mechanism involving mitochondrial dynamics that leads to age-dependent retinal pathologies.

Lee WH, Higuchi H, Ikeda S, Macke EL, Takimoto T, Pattnaik BR, Liu C, Chu LF, Siepka SM, Krentz KJ, Rubinstein CD, Kalejta RF, Thomson JA, Mullins RF, Takahashi JS, Pinto LH, Ikeda A.

Elife. 2016 Nov 15;5. pii: e19264. doi: 10.7554/eLife.19264.

2.

Competing E3 ubiquitin ligases govern circadian periodicity by degradation of CRY in nucleus and cytoplasm.

Yoo SH, Mohawk JA, Siepka SM, Shan Y, Huh SK, Hong HK, Kornblum I, Kumar V, Koike N, Xu M, Nussbaum J, Liu X, Chen Z, Chen ZJ, Green CB, Takahashi JS.

Cell. 2013 Feb 28;152(5):1091-105. doi: 10.1016/j.cell.2013.01.055.

3.

Generation of N-ethyl-N-nitrosourea (ENU) diabetes models in mice demonstrates genotype-specific action of glucokinase activators.

Fenner D, Odili S, Hong HK, Kobayashi Y, Kohsaka A, Siepka SM, Vitaterna MH, Chen P, Zelent B, Grimsby J, Takahashi JS, Matschinsky FM, Bass J.

J Biol Chem. 2011 Nov 11;286(45):39560-72. doi: 10.1074/jbc.M111.269100. Epub 2011 Sep 15.

4.
5.

Genetics and neurobiology of circadian clocks in mammals.

Siepka SM, Yoo SH, Park J, Lee C, Takahashi JS.

Cold Spring Harb Symp Quant Biol. 2007;72:251-259. doi: 10.1101/sqb.2007.72.052. Review.

6.

Gene-environment interactions in a mutant mouse kindred with native airway constrictor hyperresponsiveness.

Pinto LH, Eaton E, Chen B, Fleisher J, Shuster D, McCauley J, Kedainis D, Siepka SM, Shimomura K, Song EJ, Husain A, Lakser OJ, Mitchell RW, Dowell ML, Brown M, Camoretti-Mercado B, Naclerio R, Sperling AI, Levin SI, Turek FW, Solway J.

Mamm Genome. 2008 Jan;19(1):2-14. doi: 10.1007/s00335-007-9082-9. Epub 2008 Jan 1.

PMID:
18167028
7.

Circadian mutant Overtime reveals F-box protein FBXL3 regulation of cryptochrome and period gene expression.

Siepka SM, Yoo SH, Park J, Song W, Kumar V, Hu Y, Lee C, Takahashi JS.

Cell. 2007 Jun 1;129(5):1011-23. Epub 2007 Apr 26.

8.

Generation, identification and functional characterization of the nob4 mutation of Grm6 in the mouse.

Pinto LH, Vitaterna MH, Shimomura K, Siepka SM, Balannik V, McDearmon EL, Omura C, Lumayag S, Invergo BM, Glawe B, Cantrell DR, Inayat S, Olvera MA, Vessey KA, McCall MA, Maddox D, Morgans CW, Young B, Pletcher MT, Mullins RF, Troy JB, Takahashi JS.

Vis Neurosci. 2007 Jan-Feb;24(1):111-23.

9.

Utilization of a whole genome SNP panel for efficient genetic mapping in the mouse.

Moran JL, Bolton AD, Tran PV, Brown A, Dwyer ND, Manning DK, Bjork BC, Li C, Montgomery K, Siepka SM, Vitaterna MH, Takahashi JS, Wiltshire T, Kwiatkowski DJ, Kucherlapati R, Beier DR.

Genome Res. 2006 Mar;16(3):436-40. Epub 2006 Feb 3.

10.

Generation, characterization, and molecular cloning of the Noerg-1 mutation of rhodopsin in the mouse.

Pinto LH, Vitaterna MH, Shimomura K, Siepka SM, McDearmon EL, Fenner D, Lumayag SL, Omura C, Andrews AW, Baker M, Invergo BM, Olvera MA, Heffron E, Mullins RF, Sheffield VC, Stone EM, Takahashi JS.

Vis Neurosci. 2005 Sep-Oct;22(5):619-29.

PMID:
16332273
11.

Methods to record circadian rhythm wheel running activity in mice.

Siepka SM, Takahashi JS.

Methods Enzymol. 2005;393:230-9.

12.

Forward genetic screens to identify circadian rhythm mutants in mice.

Siepka SM, Takahashi JS.

Methods Enzymol. 2005;393:219-29.

13.

Implementing large-scale ENU mutagenesis screens in North America.

Clark AT, Goldowitz D, Takahashi JS, Vitaterna MH, Siepka SM, Peters LL, Frankel WN, Carlson GA, Rossant J, Nadeau JH, Justice MJ.

Genetica. 2004 Sep;122(1):51-64. Review.

14.

Results from screening over 9000 mutation-bearing mice for defects in the electroretinogram and appearance of the fundus.

Pinto LH, Vitaterna MH, Siepka SM, Shimomura K, Lumayag S, Baker M, Fenner D, Mullins RF, Sheffield VC, Stone EM, Heffron E, Takahashi JS.

Vision Res. 2004 Dec;44(28):3335-45.

15.

PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues.

Yoo SH, Yamazaki S, Lowrey PL, Shimomura K, Ko CH, Buhr ED, Siepka SM, Hong HK, Oh WJ, Yoo OJ, Menaker M, Takahashi JS.

Proc Natl Acad Sci U S A. 2004 Apr 13;101(15):5339-46. Epub 2004 Feb 12.

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