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Items: 1 to 50 of 66

1.

Large-scale ruminant genome sequencing provides insights into their evolution and distinct traits.

Chen L, Qiu Q, Jiang Y, Wang K, Lin Z, Li Z, Bibi F, Yang Y, Wang J, Nie W, Su W, Liu G, Li Q, Fu W, Pan X, Liu C, Yang J, Zhang C, Yin Y, Wang Y, Zhao Y, Zhang C, Wang Z, Qin Y, Liu W, Wang B, Ren Y, Zhang R, Zeng Y, da Fonseca RR, Wei B, Li R, Wan W, Zhao R, Zhu W, Wang Y, Duan S, Gao Y, Zhang YE, Chen C, Hvilsom C, Epps CW, Chemnick LG, Dong Y, Mirarab S, Siegismund HR, Ryder OA, Gilbert MTP, Lewin HA, Zhang G, Heller R, Wang W.

Science. 2019 Jun 21;364(6446). pii: eaav6202. doi: 10.1126/science.aav6202.

PMID:
31221828
2.

The Muskox Lost a Substantial Part of Its Genetic Diversity on Its Long Road to Greenland.

Hansen CCR, Hvilsom C, Schmidt NM, Aastrup P, Van Coeverden de Groot PJ, Siegismund HR, Heller R.

Curr Biol. 2018 Dec 17;28(24):4022-4028.e5. doi: 10.1016/j.cub.2018.10.054. Epub 2018 Dec 6.

PMID:
30528581
3.

A southern African origin and cryptic structure in the highly mobile plains zebra.

Pedersen CT, Albrechtsen A, Etter PD, Johnson EA, Orlando L, Chikhi L, Siegismund HR, Heller R.

Nat Ecol Evol. 2018 Mar;2(3):491-498. doi: 10.1038/s41559-017-0453-7. Epub 2018 Jan 22.

PMID:
29358610
4.

Extinctions, genetic erosion and conservation options for the black rhinoceros (Diceros bicornis).

Moodley Y, Russo IM, Dalton DL, Kotzé A, Muya S, Haubensak P, Bálint B, Munimanda GK, Deimel C, Setzer A, Dicks K, Herzig-Straschil B, Kalthoff DC, Siegismund HR, Robovský J, O'Donoghue P, Bruford MW.

Sci Rep. 2017 Feb 8;7:41417. doi: 10.1038/srep41417.

5.

The Effect of an Extreme and Prolonged Population Bottleneck on Patterns of Deleterious Variation: Insights from the Greenlandic Inuit.

Pedersen CT, Lohmueller KE, Grarup N, Bjerregaard P, Hansen T, Siegismund HR, Moltke I, Albrechtsen A.

Genetics. 2017 Feb;205(2):787-801. doi: 10.1534/genetics.116.193821. Epub 2016 Nov 30.

6.

Chimpanzee genomic diversity reveals ancient admixture with bonobos.

de Manuel M, Kuhlwilm M, Frandsen P, Sousa VC, Desai T, Prado-Martinez J, Hernandez-Rodriguez J, Dupanloup I, Lao O, Hallast P, Schmidt JM, Heredia-Genestar JM, Benazzo A, Barbujani G, Peter BM, Kuderna LF, Casals F, Angedakin S, Arandjelovic M, Boesch C, Kühl H, Vigilant L, Langergraber K, Novembre J, Gut M, Gut I, Navarro A, Carlsen F, Andrés AM, Siegismund HR, Scally A, Excoffier L, Tyler-Smith C, Castellano S, Xue Y, Hvilsom C, Marques-Bonet T.

Science. 2016 Oct 28;354(6311):477-481. Epub 2016 Oct 27.

7.

Unrecognized circulation of SAT 1 foot-and-mouth disease virus in cattle herds around Queen Elizabeth National Park in Uganda.

Dhikusooka MT, Ayebazibwe C, Namatovu A, Belsham GJ, Siegismund HR, Wekesa SN, Balinda SN, Muwanika VB, Tjørnehøj K.

BMC Vet Res. 2016 Jan 6;12:5. doi: 10.1186/s12917-015-0616-1.

8.

Time Clustered Sampling Can Inflate the Inferred Substitution Rate in Foot-And-Mouth Disease Virus Analyses.

Pedersen CE, Frandsen P, Wekesa SN, Heller R, Sangula AK, Wadsworth J, Knowles NJ, Muwanika VB, Siegismund HR.

PLoS One. 2015 Dec 2;10(12):e0143605. doi: 10.1371/journal.pone.0143605. eCollection 2015.

9.

Mountain gorilla genomes reveal the impact of long-term population decline and inbreeding.

Xue Y, Prado-Martinez J, Sudmant PH, Narasimhan V, Ayub Q, Szpak M, Frandsen P, Chen Y, Yngvadottir B, Cooper DN, de Manuel M, Hernandez-Rodriguez J, Lobon I, Siegismund HR, Pagani L, Quail MA, Hvilsom C, Mudakikwa A, Eichler EE, Cranfield MR, Marques-Bonet T, Tyler-Smith C, Scally A.

Science. 2015 Apr 10;348(6231):242-245. doi: 10.1126/science.aaa3952. Epub 2015 Apr 9.

10.

Inference of purifying and positive selection in three subspecies of chimpanzees (Pan troglodytes) from exome sequencing.

Bataillon T, Duan J, Hvilsom C, Jin X, Li Y, Skov L, Glemin S, Munch K, Jiang T, Qian Y, Hobolth A, Wang J, Mailund T, Siegismund HR, Schierup MH.

Genome Biol Evol. 2015 Mar 30;7(4):1122-32. doi: 10.1093/gbe/evv058.

11.

Genetic consequences of population expansions and contractions in the common hippopotamus (Hippopotamus amphibius) since the Late Pleistocene.

Stoffel C, Dufresnes C, Okello JB, Noirard C, Joly P, Nyakaana S, Muwanika VB, Alcala N, Vuilleumier S, Siegismund HR, Fumagalli L.

Mol Ecol. 2015 May;24(10):2507-20. doi: 10.1111/mec.13179. Epub 2015 Apr 22.

PMID:
25827243
12.

Characterization of foot-and-mouth disease viruses (FMDVs) from Ugandan cattle outbreaks during 2012-2013: evidence for circulation of multiple serotypes.

Namatovu A, Tjørnehøj K, Belsham GJ, Dhikusooka MT, Wekesa SN, Muwanika VB, Siegismund HR, Ayebazibwe C.

PLoS One. 2015 Feb 9;10(2):e0114811. doi: 10.1371/journal.pone.0114811. eCollection 2015.

13.

Characterisation of recent foot-and-mouth disease viruses from African buffalo (Syncerus caffer) and cattle in Kenya is consistent with independent virus populations.

Wekesa SN, Sangula AK, Belsham GJ, Tjornehoj K, Muwanika VB, Gakuya F, Mijele D, Siegismund HR.

BMC Vet Res. 2015 Feb 3;11:17. doi: 10.1186/s12917-015-0333-9.

14.

Foot-and-mouth disease virus serotype SAT 3 in long-horned Ankole calf, Uganda.

Dhikusooka MT, Tjørnehøj K, Ayebazibwe C, Namatovu A, Ruhweza S, Siegismund HR, Wekesa SN, Normann P, Belsham GJ.

Emerg Infect Dis. 2015 Jan;21(1):111-4. doi: 10.3201/eid2101.140995.

15.

Is diagnosability an indicator of speciation? Response to "Why one century of phenetics is enough".

Heller R, Frandsen P, Lorenzen ED, Siegismund HR.

Syst Biol. 2014 Sep;63(5):833-7. doi: 10.1093/sysbio/syu034. Epub 2014 May 15. No abstract available.

PMID:
24831669
16.

Integrating genetic data and population viability analyses for the identification of harbour seal (Phoca vitulina) populations and management units.

Olsen MT, Andersen LW, Dietz R, Teilmann J, Härkönen T, Siegismund HR.

Mol Ecol. 2014 Feb;23(4):815-31. doi: 10.1111/mec.12644.

PMID:
24382213
17.

Genetic diversity of serotype A foot-and-mouth disease viruses in Kenya from 1964 to 2013; implications for control strategies in eastern Africa.

Wekesa SN, Sangula AK, Belsham GJ, Muwanika VB, Heller R, Balinda SN, Masembe C, Siegismund HR.

Infect Genet Evol. 2014 Jan;21:408-17. doi: 10.1016/j.meegid.2013.12.006. Epub 2013 Dec 22.

PMID:
24368254
18.

Challenges for Serology-Based Characterization of Foot-and-Mouth Disease Outbreaks in Endemic Areas; Identification of Two Separate Lineages of Serotype O FMDV in Uganda in 2011.

Namatovu A, Belsham GJ, Ayebazibwe C, Dhikusooka MT, Wekesa SN, Siegismund HR, Muwanika VB, Tjørnehøj K.

Transbound Emerg Dis. 2015 Oct;62(5):522-34. doi: 10.1111/tbed.12170. Epub 2013 Oct 11.

PMID:
24118785
19.

Contrasting demographic histories of the neighboring bonobo and chimpanzee.

Hvilsom C, Carlsen F, Heller R, Jaffré N, Siegismund HR.

Primates. 2014 Jan;55(1):101-12. doi: 10.1007/s10329-013-0373-3. Epub 2013 Aug 27.

PMID:
23982179
20.

Analysis of Recent Serotype O Foot-and-Mouth Disease Viruses from Livestock in Kenya: Evidence of Four Independently Evolving Lineages.

Wekesa SN, Muwanika VB, Siegismund HR, Sangula AK, Namatovu A, Dhikusooka MT, Tjørnehøj K, Balinda SN, Wadsworth J, Knowles NJ, Belsham GJ.

Transbound Emerg Dis. 2015 Jun;62(3):305-14. doi: 10.1111/tbed.12152. Epub 2013 Aug 12.

PMID:
23931583
21.

The confounding effect of population structure on Bayesian skyline plot inferences of demographic history.

Heller R, Chikhi L, Siegismund HR.

PLoS One. 2013 May 7;8(5):e62992. doi: 10.1371/journal.pone.0062992. Print 2013.

22.

Understanding geographic origins and history of admixture among chimpanzees in European zoos, with implications for future breeding programmes.

Hvilsom C, Frandsen P, Børsting C, Carlsen F, Sallé B, Simonsen BT, Siegismund HR.

Heredity (Edinb). 2013 Jun;110(6):586-93. doi: 10.1038/hdy.2013.9. Epub 2013 Mar 27.

23.

Are there really twice as many bovid species as we thought?

Heller R, Frandsen P, Lorenzen ED, Siegismund HR.

Syst Biol. 2013 May 1;62(3):490-3. doi: 10.1093/sysbio/syt004. Epub 2013 Jan 29. No abstract available.

PMID:
23362112
24.

Cape buffalo mitogenomics reveals a Holocene shift in the African human-megafauna dynamics.

Heller R, Brüniche-Olsen A, Siegismund HR.

Mol Ecol. 2012 Aug;21(16):3947-59. doi: 10.1111/j.1365-294X.2012.05671.x. Epub 2012 Jun 22. Erratum in: Mol Ecol. 2013 Apr;22(7):2060.

PMID:
22725969
25.

Comparative phylogeography of African savannah ungulates.

Lorenzen ED, Heller R, Siegismund HR.

Mol Ecol. 2012 Aug;21(15):3656-70. doi: 10.1111/j.1365-294X.2012.05650.x. Epub 2012 Jun 15. Review.

PMID:
22702960
26.

Extensive X-linked adaptive evolution in central chimpanzees.

Hvilsom C, Qian Y, Bataillon T, Li Y, Mailund T, Sallé B, Carlsen F, Li R, Zheng H, Jiang T, Jiang H, Jin X, Munch K, Hobolth A, Siegismund HR, Wang J, Schierup MH.

Proc Natl Acad Sci U S A. 2012 Feb 7;109(6):2054-9. doi: 10.1073/pnas.1106877109. Epub 2012 Jan 23.

27.

Serotype identification and VP1 coding sequence analysis of foot-and-mouth disease viruses from outbreaks in eastern and northern Uganda in 2008/9.

Kasambula L, Belsham GJ, Siegismund HR, Muwanika VB, Ademun-Okurut AR, Masembe C.

Transbound Emerg Dis. 2012 Aug;59(4):323-30. doi: 10.1111/j.1865-1682.2011.01276.x. Epub 2011 Nov 28.

PMID:
22117844
28.

The role of African buffalos (Syncerus caffer) in the maintenance of foot-and-mouth disease in Uganda.

Ayebazibwe C, Mwiine FN, Tjørnehøj K, Balinda SN, Muwanika VB, Ademun Okurut AR, Belsham GJ, Normann P, Siegismund HR, Alexandersen S.

BMC Vet Res. 2010 Dec 11;6:54. doi: 10.1186/1746-6148-6-54.

29.

Evolutionary analysis of foot-and-mouth disease virus serotype SAT 1 isolates from east Africa suggests two independent introductions from southern Africa.

Sangula AK, Belsham GJ, Muwanika VB, Heller R, Balinda SN, Masembe C, Siegismund HR.

BMC Evol Biol. 2010 Nov 30;10:371. doi: 10.1186/1471-2148-10-371.

30.

Phylogenetic analyses of the polyprotein coding sequences of serotype O foot-and-mouth disease viruses in East Africa: evidence for interserotypic recombination.

Balinda SN, Siegismund HR, Muwanika VB, Sangula AK, Masembe C, Ayebazibwe C, Normann P, Belsham GJ.

Virol J. 2010 Aug 23;7:199. doi: 10.1186/1743-422X-7-199.

31.

Genetic diversity among ancient Nordic populations.

Melchior L, Lynnerup N, Siegismund HR, Kivisild T, Dissing J.

PLoS One. 2010 Jul 30;5(7):e11898. doi: 10.1371/journal.pone.0011898.

32.

Diversity and transboundary mobility of serotype O foot-and-mouth disease virus in East Africa: implications for vaccination policies.

Balinda SN, Sangula AK, Heller R, Muwanika VB, Belsham GJ, Masembe C, Siegismund HR.

Infect Genet Evol. 2010 Oct;10(7):1058-65. doi: 10.1016/j.meegid.2010.06.017. Epub 2010 Jul 7.

PMID:
20619358
33.

Co-circulation of two extremely divergent serotype SAT 2 lineages in Kenya highlights challenges to foot-and-mouth disease control.

Sangula AK, Belsham GJ, Muwanika VB, Heller R, Balinda SN, Siegismund HR.

Arch Virol. 2010 Oct;155(10):1625-30. doi: 10.1007/s00705-010-0742-9. Epub 2010 Jul 8.

PMID:
20614146
34.

Antibodies against foot-and-mouth disease (FMD) virus in African buffalos (Syncerus caffer) in selected National Parks in Uganda (2001-2003).

Ayebazibwe C, Mwiine FN, Balinda SN, Tjørnehøj K, Masembe C, Muwanika VB, Okurut AR, Siegismund HR, Alexandersen S.

Transbound Emerg Dis. 2010 Aug 1;57(4):286-92. doi: 10.1111/j.1865-1682.2010.01147.x. Epub 2010 Jun 18.

PMID:
20561289
35.

Patterns, risk factors and characteristics of reported and perceived foot-and-mouth disease (FMD) in Uganda.

Ayebazibwe C, Tjørnehøj K, Mwiine FN, Muwanika VB, Okurut AR, Siegismund HR, Alexandersen S.

Trop Anim Health Prod. 2010 Oct;42(7):1547-59. doi: 10.1007/s11250-010-9605-3. Epub 2010 Jun 6.

PMID:
20526861
36.

Low diversity of foot-and-mouth disease serotype C virus in Kenya: evidence for probable vaccine strain re-introductions in the field.

Sangula AK, Siegismund HR, Belsham GJ, Balinda SN, Masembe C, Muwanika VB.

Epidemiol Infect. 2011 Feb;139(2):189-96. doi: 10.1017/S0950268810000580. Epub 2010 Mar 25.

PMID:
20334728
37.

Molecular characterization of SAT 2 foot-and-mouth disease virus from post-outbreak slaughtered animals: implications for disease control in Uganda.

Balinda SN, Belsham GJ, Masembe C, Sangula AK, Siegismund HR, Muwanika VB.

Epidemiol Infect. 2010 Aug;138(8):1204-10. doi: 10.1017/S0950268809991427. Epub 2009 Dec 14.

PMID:
20003615
38.

Prevalence estimates of antibodies towards foot-and-mouth disease virus in small ruminants in Uganda.

Balinda SN, Tjørnehøj K, Muwanika VB, Sangula AK, Mwiine FN, Ayebazibwe C, Masembe C, Siegismund HR, Alexandersen S.

Transbound Emerg Dis. 2009 Dec;56(9-10):362-71. doi: 10.1111/j.1865-1682.2009.01094.x.

PMID:
19909475
39.

Genetic variation of inbreeding depression among floral and fitness traits in Silene nutans.

Thiele J, Hansen T, Siegismund HR, Hauser TP.

Heredity (Edinb). 2010 Jan;104(1):52-60. doi: 10.1038/hdy.2009.103.

40.

Relationship between three measures of genetic differentiation G(ST), D(EST) and G'(ST): how wrong have we been?

Heller R, Siegismund HR.

Mol Ecol. 2009 May;18(10):2080-3; discussion 2088-91. No abstract available.

PMID:
19645078
41.

Where sociality and relatedness diverge: the genetic basis for hierarchical social organization in African elephants.

Wittemyer G, Okello JB, Rasmussen HB, Arctander P, Nyakaana S, Douglas-Hamilton I, Siegismund HR.

Proc Biol Sci. 2009 Oct 7;276(1672):3513-21. doi: 10.1098/rspb.2009.0941. Epub 2009 Jul 15.

42.

Mid-Holocene decline in African buffalos inferred from Bayesian coalescent-based analyses of microsatellites and mitochondrial DNA.

Heller R, Lorenzen ED, Okello JB, Masembe C, Siegismund HR.

Mol Ecol. 2008 Nov;17(22):4845-58. doi: 10.1111/j.1365-294X.2008.03961.x.

PMID:
19140976
43.

Genetic subspecies diversity of the chimpanzee CD4 virus-receptor gene.

Hvilsom C, Carlsen F, Siegismund HR, Corbet S, Nerrienet E, Fomsgaard A.

Genomics. 2008 Nov;92(5):322-8. doi: 10.1016/j.ygeno.2008.07.003. Epub 2008 Sep 18.

44.

Effective population size dynamics reveal impacts of historic climatic events and recent anthropogenic pressure in African elephants.

Okello JB, Wittemyer G, Rasmussen HB, Arctander P, Nyakaana S, Douglas-Hamilton I, Siegismund HR.

Mol Ecol. 2008 Sep;17(17):3788-99. doi: 10.1111/j.1365-294X.2008.03871.x. Epub 2008 Jul 16.

PMID:
18643879
45.

Population genetic structure of savannah elephants in Kenya: conservation and management implications.

Okello JB, Masembe C, Rasmussen HB, Wittemyer G, Omondi P, Kahindi O, Muwanika VB, Arctander P, Douglas-Hamilton I, Nyakaana S, Siegismund HR.

J Hered. 2008 Sep-Oct;99(5):443-52. doi: 10.1093/jhered/esn028. Epub 2008 May 13.

PMID:
18477589
46.

High variation and very low differentiation in wide ranging plains zebra (Equus quagga): insights from mtDNA and microsatellites.

Lorenzen ED, Arctander P, Siegismund HR.

Mol Ecol. 2008 Jun;17(12):2812-24. doi: 10.1111/j.1365-294X.2008.03781.x. Epub 2008 May 6.

PMID:
18466230
47.

Phylogeography, hybridization and Pleistocene refugia of the kob antelope (Kobus kob).

Lorenzen ED, De Neergaard R, Arctander P, Siegismund HR.

Mol Ecol. 2007 Aug;16(15):3241-52.

PMID:
17651200
48.

Hybridization between subspecies of waterbuck (Kobus ellipsiprymnus) in zones of overlap with limited introgression.

Lorenzen ED, Simonsen BT, Kat PW, Arctander P, Siegismund HR.

Mol Ecol. 2006 Oct;15(12):3787-99.

PMID:
17032274
49.

Reproductive success of bromadiolone-resistant rats in absence of anticoagulant pressure.

Heiberg AC, Leirs H, Siegismund HR.

Pest Manag Sci. 2006 Sep;62(9):862-71.

PMID:
16789046
50.

Regional genetic structuring and evolutionary history of the impala Aepyceros melampus.

Lorenzen ED, Arctander P, Siegismund HR.

J Hered. 2006 Mar-Apr;97(2):119-32. Epub 2006 Jan 11.

PMID:
16407525

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