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Items: 1 to 50 of 78

1.

Increased liver echogenicity and liver enzymes are associated with extreme obesity, adolescent age and male gender: analysis from the German/Austrian/Swiss obesity registry APV.

Greber-Platzer S, Thajer A, Bohn S, Brunert A, Boerner F, Siegfried W, Artlich A, Moeckel A, Waldecker-Krebs H, Pauer S, Holl RW; APV-Study Group.

BMC Pediatr. 2019 Sep 12;19(1):332. doi: 10.1186/s12887-019-1711-4.

2.

Cardiometabolic risk factors differ among adolescents with obesity in three European countries - a cross-sectional study.

Benestad B, Júlíusson PB, Siegfried W, Lekhal S, Småstuen MC, Hertel JK, Agosti F, Marazzi N, Hjelmesaeth J, Sartorio A.

Acta Paediatr. 2019 Mar;108(3):493-501. doi: 10.1111/apa.14542. Epub 2018 Sep 17.

3.

[Case series: BMI long courses in patients with extreme juvenile obesity. Short- and long-term success of long-term inpatient treatment].

Brandt S, König D, Lennerz B, Schoosleitner C, Schäfer A, Siegfried A, Siegfried W, Wabitsch M.

MMW Fortschr Med. 2016 Aug;158 Suppl 5:1-7. doi: 10.1007/s15006-016-8606-1. Epub 2016 Aug 26. German.

PMID:
27565483
4.

Stereoselective Metabolism of the Sterol Biosynthesis Inhibitor Fungicides Fenpropidin, Fenpropimorph, and Spiroxamine in Grapes, Sugar Beets, and Wheat.

Buerge IJ, Krauss J, López-Cabeza R, Siegfried W, Stüssi M, Wettstein FE, Poiger T.

J Agric Food Chem. 2016 Jul 6;64(26):5301-9. doi: 10.1021/acs.jafc.6b00919. Epub 2016 Jun 24.

PMID:
27248479
5.

Sonographically Assessed Intra-Abdominal Fat And Cardiometabolic Risk Factors in Adolescents with Extreme Obesity.

Moss A, Sievert K, Siegfried W, Siegfried A, Brandt S, Koenig W, Wabitsch M.

Obes Facts. 2016;9(2):121-37. doi: 10.1159/000443690. Epub 2016 Apr 8.

6.

BMI or BIA: Is Body Mass Index or Body Fat Mass a Better Predictor of Cardiovascular Risk in Overweight or Obese Children and Adolescents? A German/Austrian/Swiss Multicenter APV Analysis of 3,327 Children and Adolescents.

Bohn B, Müller MJ, Simic-Schleicher G, Kiess W, Siegfried W, Oelert M, Tuschy S, Berghem S, Holl RW; APV Initiative and the German BMBF Competence Network Obesity.

Obes Facts. 2015;8(2):156-65. doi: 10.1159/000381227. Epub 2015 Apr 15.

7.

Blood pressure in 57,915 pediatric patients who are overweight or obese based on five reference systems.

Flechtner-Mors M, Neuhauser H, Reinehr T, Roost HP, Wiegand S, Siegfried W, Zwiauer K, Molz E, Holl RW; APV initiative and the BMBF Competence Network Obesity.

Am J Cardiol. 2015 Jun 1;115(11):1587-94. doi: 10.1016/j.amjcard.2015.02.063. Epub 2015 Mar 14.

PMID:
25862158
8.

Re-entering obesity prevention: a qualitative-empirical inquiry into the subjective aetiology of extreme obese adolescents.

Braun M, Schell J, Siegfried W, Müller MJ, Ried J.

BMC Public Health. 2014 Sep 20;14:977. doi: 10.1186/1471-2458-14-977.

9.

Multidisciplinary approach to the treatment of obese adolescents: effects on cardiovascular risk factors, inflammatory profile, and neuroendocrine regulation of energy balance.

Dâmaso AR, de Piano A, Campos RM, Corgosinho FC, Siegfried W, Caranti DA, Masquio DC, Carnier J, Sanches Pde L, Leão da Silva P, Nascimento CM, Oyama LM, Dantas AD, de Mello MT, Tufik S, Tock L.

Int J Endocrinol. 2013;2013:541032. doi: 10.1155/2013/541032. Epub 2013 Oct 27.

10.

Impaired HDL function in obese adolescents: impact of lifestyle intervention and bariatric surgery.

Matsuo Y, Oberbach A, Till H, Inge TH, Wabitsch M, Moss A, Jehmlich N, Völker U, Müller U, Siegfried W, Kanesawa N, Kurabayashi M, Schuler G, Linke A, Adams V.

Obesity (Silver Spring). 2013 Dec;21(12):E687-95. doi: 10.1002/oby.20538. Epub 2013 Aug 13.

11.

Comorbidities in overweight children and adolescents: do we treat them effectively?

Reinehr T, Wiegand S, Siegfried W, Keller KM, Widhalm K, l'Allemand D, Zwiauer K, Holl RW.

Int J Obes (Lond). 2013 Apr;37(4):493-9. doi: 10.1038/ijo.2012.184. Epub 2012 Nov 13.

PMID:
23147116
12.

The metabolic syndrome among obese adolescents.

Sartorio A, Agosti F, De Col A, Compri E, Grugni G, Siegfried W, Adorni F, Lafortuna CL.

J Endocrinol Invest. 2011 Oct;34(9):729-30. No abstract available.

PMID:
22156905
13.

[Treatment of extremely obese adolescents and young adults at the Insula Obesity Center in Bischofswiesen].

Siegfried W, Tobar A, Vogl C, Eder A, Kunze D.

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2011 May;54(5):621-7. doi: 10.1007/s00103-011-1274-5. German.

PMID:
21547655
14.

Feasibility of activity-promoting video games among obese adolescents and young adults in a clinical setting.

Radon K, Fürbeck B, Thomas S, Siegfried W, Nowak D, von Kries R.

J Sci Med Sport. 2011 Jan;14(1):42-5. doi: 10.1016/j.jsams.2010.07.009. Epub 2010 Sep 15.

PMID:
20837400
15.

Prevalence of the metabolic syndrome among extremely obese adolescents in Italy and Germany.

Lafortuna CL, Adorni F, Agosti F, De Col A, Sievert K, Siegfried W, Sartorio A.

Diabetes Res Clin Pract. 2010 Apr;88(1):14-21. doi: 10.1016/j.diabres.2010.01.008. Epub 2010 Jan 21.

PMID:
20096473
16.

Procolipase gene: no association with early-onset obesity or fat intake.

Wermter AK, Scherag A, Holter K, Reichwald K, Lichtner P, Siegfried W, Blundell J, Lawton C, Whybrow S, Stubbs J, Arch JR, Meitinger T, Platzer M, Hinney A, Hebebrand J.

Obes Facts. 2009;2(1):40-4. doi: 10.1159/000196379. Epub 2009 Feb 9.

17.

Effects of long-term multidisciplinary inpatient therapy on body composition of severely obese adolescents.

Prado WL, Siegfried A, Dâmaso AR, Carnier J, Piano Ad, Siegfried W.

J Pediatr (Rio J). 2009 May-Jun;85(3):243-8. doi: 10.2223/JPED.1889. English, Portuguese.

18.

[Reduction of stigma against obese people: effects of an educational film].

Hennings A, Hilbert A, Thomas J, Siegfried W, Rief W.

Psychother Psychosom Med Psychol. 2007 Sep-Oct;57(9-10):359-63. German.

PMID:
17614091
19.

Analysis of sequence variations in the suppressor of cytokine signaling (SOCS)-3 gene in extremely obese children and adolescents.

Hölter K, Wermter AK, Scherag A, Siegfried W, Goldschmidt H, Hebebrand J, Hinney A.

BMC Med Genet. 2007 Apr 19;8:21.

20.

[Long-term inpatient treatment of extreme juvenile obesity: an 18-month catamnestic study].

Siegfried W, Kromeyer-Hauschild K, Zabel G, Siegfried A, Wabitsch M, Holl RW.

MMW Fortschr Med. 2006 Aug 31;148(35-36):39-41. Review. German.

PMID:
16995363
21.

Mutation analysis of the MCHR1 gene in human obesity.

Wermter AK, Reichwald K, Büch T, Geller F, Platzer C, Huse K, Hess C, Remschmidt H, Gudermann T, Preibisch G, Siegfried W, Goldschmidt HP, Li WD, Price RA, Biebermann H, Krude H, Vollmert C, Wichmann HE, Illig T, Sørensen TI, Astrup A, Larsen LH, Pedersen O, Eberlé D, Clément K, Blundell J, Wabitsch M, Schäfer H, Platzer M, Hinney A, Hebebrand J.

Eur J Endocrinol. 2005 Jun;152(6):851-62.

PMID:
15941924
22.

Human galanin (GAL) and galanin 1 receptor (GALR1) variations are not involved in fat intake and early onset obesity.

Schäuble N, Reichwald K, Grassl W, Bechstein H, Müller HC, Scherag A, Geller F, Utting M, Siegfried W, Goldschmidt H, Blundell J, Lawton C, Alam R, Whybrow S, Stubbs J, Platzer M, Hebebrand J, Hinney A.

J Nutr. 2005 Jun;135(6):1387-92.

PMID:
15930442
23.

Mutation screen of the brain derived neurotrophic factor gene (BDNF): identification of several genetic variants and association studies in patients with obesity, eating disorders, and attention-deficit/hyperactivity disorder.

Friedel S, Horro FF, Wermter AK, Geller F, Dempfle A, Reichwald K, Smidt J, Brönner G, Konrad K, Herpertz-Dahlmann B, Warnke A, Hemminger U, Linder M, Kiefl H, Goldschmidt HP, Siegfried W, Remschmidt H, Hinney A, Hebebrand J.

Am J Med Genet B Neuropsychiatr Genet. 2005 Jan 5;132B(1):96-9.

PMID:
15457498
24.

Medical care of obese children and adolescents. APV: a standardised multicentre documentation derived to study initial presentation and cardiovascular risk factors in patients transferred to specialised treatment institutions.

Reinehr T, Wabitsch M, Andler W, Beyer P, Böttner A, Chen-Stute A, Fromme C, Hampel O, Keller KM, Kilian U, Kolbe H, Lob-Corzilius T, Marg W, Mayer H, Mohnike K, Oepen J, Povel C, Richter B, Riedinger N, Schauerte G, Schmahlfeldt G, Siegfried W, Smuda P, Stachow R, van Egmond-Fröhlich A, Weiten J, Wiegand S, Witte S, Zindel V, Holl RW; APV Study Group.

Eur J Pediatr. 2004 Jun;163(6):308-12.

PMID:
15346912
25.

Melanocortin-4 receptor gene: case-control study and transmission disequilibrium test confirm that functionally relevant mutations are compatible with a major gene effect for extreme obesity.

Hinney A, Hohmann S, Geller F, Vogel C, Hess C, Wermter AK, Brokamp B, Goldschmidt H, Siegfried W, Remschmidt H, Schäfer H, Gudermann T, Hebebrand J.

J Clin Endocrinol Metab. 2003 Sep;88(9):4258-67.

PMID:
12970296
26.

Long-Term Monitoring for Resistance of Botryotinia fuckeliana to Anilinopyrimidine, Phenylpyrrole, and Hydroxyanilide Fungicides in Switzerland.

Baroffio CA, Siegfried W, Hilber UW.

Plant Dis. 2003 Jun;87(6):662-666. doi: 10.1094/PDIS.2003.87.6.662.

PMID:
30812857
27.

No evidence for involvement of the promoter polymorphism -866 G/A of the UCP2 gene in childhood-onset obesity in humans.

Schäuble N, Geller F, Siegfried W, Goldschmidt H, Remschmidt H, Hinney A, Hebebrand J.

Exp Clin Endocrinol Diabetes. 2003 Apr;111(2):73-6.

PMID:
12746756
28.

Genome scan for childhood and adolescent obesity in German families.

Saar K, Geller F, Rüschendorf F, Reis A, Friedel S, Schäuble N, Nürnberg P, Siegfried W, Goldschmidt HP, Schäfer H, Ziegler A, Remschmidt H, Hinney A, Hebebrand J.

Pediatrics. 2003 Feb;111(2):321-7.

PMID:
12563058
29.

No evidence for involvement of the calpain-10 gene 'high-risk' haplotype combination for non-insulin-dependent diabetes mellitus in early onset obesity.

Hinney A, Antwerpen B, Geller F, Schäfer H, Siegfried W, Goldschmidt H, Remschmidt H, Ziegler A, Hebebrand J.

Mol Genet Metab. 2002 Jun;76(2):152-6.

PMID:
12083814
30.

Ghrelin gene: identification of missense variants and a frameshift mutation in extremely obese children and adolescents and healthy normal weight students.

Hinney A, Hoch A, Geller F, Schäfer H, Siegfried W, Goldschmidt H, Remschmidt H, Hebebrand J.

J Clin Endocrinol Metab. 2002 Jun;87(6):2716.

PMID:
12050239
31.

Snoring and Sleep Apnea in Obese Adolescents: Effect of Long-term Weight Loss-Rehabilitation.

Siegfried W, Siegfried A, Rabenbauer M, Hebebrand J.

Sleep Breath. 1999;3(3):83-88.

PMID:
11898113
32.

No evidence for involvement of alleles of the 825-C/T polymorphism of the G-protein subunit beta 3 in body weight regulation.

Hinney A, Geller F, Neupert T, Sommerlad C, Gerber G, Görg T, Siegfried W, Goldschmidt H, Remschmidt H, Ziegler A, Hebebrand J.

Exp Clin Endocrinol Diabetes. 2001;109(8):402-5.

PMID:
11748488
33.

Systematic screening for mutations in the human necdin gene (NDN): identification of two naturally occurring polymorphisms and association analysis in body weight regulation.

Oeffner F, Korn T, Roth H, Ziegler A, Hinney A, Goldschmidt H, Siegfried W, Hebebrand J, Grzeschik KH.

Int J Obes Relat Metab Disord. 2001 Jun;25(6):767-9.

PMID:
11439287
35.

Identification of a deletion variant in the gene encoding the human alpha(2A)-adrenergic receptor.

Hamann A, Brieske C, Tafel J, Buttron P, Schwarzloh B, Münzberg H, Hinney A, Mayer H, Siegfried W, Hebebrand J, Greten H, Algenstaedt P, Ziegler R.

Eur J Endocrinol. 2001 Mar;144(3):291-5.

PMID:
11248750
36.

Significant association between a silent polymorphism in the neuromedin B gene and body weight in German children and adolescents.

Oeffner F, Bornholdt D, Ziegler A, Hinney A, Görg T, Gerber G, Goldschmidt HP, Siegfried W, Wright A, Hebebrand J, Grzeschik KH.

Acta Diabetol. 2000;37(2):93-101.

PMID:
11194934
37.

Rates of psychiatric disorders in a clinical study group of adolescents with extreme obesity and in obese adolescents ascertained via a population based study.

Britz B, Siegfried W, Ziegler A, Lamertz C, Herpertz-Dahlmann BM, Remschmidt H, Wittchen HU, Hebebrand J.

Int J Obes Relat Metab Disord. 2000 Dec;24(12):1707-14.

PMID:
11126229
38.

Independent confirmation of a major locus for obesity on chromosome 10.

Hinney A, Ziegler A, Oeffner F, Wedewardt C, Vogel M, Wulftange H, Geller F, Stübing K, Siegfried W, Goldschmidt HP, Remschmidt H, Hebebrand J.

J Clin Endocrinol Metab. 2000 Aug;85(8):2962-5. Erratum in: J Clin Endocrinol Metab 2000 Nov;85(11):3972.

PMID:
10946912
39.

No evidence for involvement of polymorphisms of the dopamine D4 receptor gene in anorexia nervosa, underweight, and obesity.

Hinney A, Schneider J, Ziegler A, Lehmkuhl G, Poustka F, Schmidt MH, Mayer H, Siegfried W, Remschmidt H, Hebebrand J.

Am J Med Genet. 1999 Dec 15;88(6):594-7.

PMID:
10581473
40.

Phenotypes in three pedigrees with autosomal dominant obesity caused by haploinsufficiency mutations in the melanocortin-4 receptor gene.

Sina M, Hinney A, Ziegler A, Neupert T, Mayer H, Siegfried W, Blum WF, Remschmidt H, Hebebrand J.

Am J Hum Genet. 1999 Dec;65(6):1501-7.

41.

No evidence for an involvement of alleles of polymorphisms in the serotonin1Dbeta and 7 receptor genes in obesity, underweight or anorexia nervosa.

Hinney A, Herrmann H, Löhr T, Rosenkranz K, Ziegler A, Lehmkuhl G, Poustka F, Schmidt MH, Mayer H, Siegfried W, Remschmidt H, Hebebrand J.

Int J Obes Relat Metab Disord. 1999 Jul;23(7):760-3.

PMID:
10454111
42.

Missense variants in the human peroxisome proliferator-activated receptor-gamma2 gene in lean and obese subjects.

Hamann A, Münzberg H, Buttron P, Büsing B, Hinney A, Mayer H, Siegfried W, Hebebrand J, Greten H.

Eur J Endocrinol. 1999 Jul;141(1):90-2.

PMID:
10407229
43.

Missense variants in the human cholecystokinin type A receptor gene: no evidence for association with early-onset obesity.

Hamann A, Büsing B, Münzberg H, de Weerth A, Hinney A, Mayer H, Siegfried W, Hebebrand J, Greten H.

Horm Metab Res. 1999 Apr;31(4):287-8. No abstract available.

PMID:
10333087
44.

Several mutations in the melanocortin-4 receptor gene including a nonsense and a frameshift mutation associated with dominantly inherited obesity in humans.

Hinney A, Schmidt A, Nottebom K, Heibült O, Becker I, Ziegler A, Gerber G, Sina M, Görg T, Mayer H, Siegfried W, Fichter M, Remschmidt H, Hebebrand J.

J Clin Endocrinol Metab. 1999 Apr;84(4):1483-6.

PMID:
10199800
45.

Transmission disequilibrium and sequence variants at the leptin receptor gene in extremely obese German children and adolescents.

Roth H, Korn T, Rosenkranz K, Hinney A, Ziegler A, Kunz J, Siegfried W, Mayer H, Hebebrand J, Grzeschik KH.

Hum Genet. 1998 Nov;103(5):540-6.

PMID:
9860295
46.

No evidence for involvement of the leptin gene in anorexia nervosa, bulimia nervosa, underweight or early onset extreme obesity: identification of two novel mutations in the coding sequence and a novel polymorphism in the leptin gene linked upstream region.

Hinney A, Bornscheuer A, Depenbusch M, Mierke B, Tölle A, Middeke K, Ziegler A, Roth H, Gerber G, Zamzow K, Ballauff A, Hamann A, Mayer H, Siegfried W, Lehmkuhl G, Poustka F, Schmidt MH, Hermann H, Herpertz-Dahlmann BM, Fichter M, Remschmidt H, Hebebrand J.

Mol Psychiatry. 1998 Nov;3(6):539-43.

PMID:
9857981
47.

Systematic mutation screening of the estrogen receptor beta gene in probands of different weight extremes: identification of several genetic variants.

Rosenkranz K, Hinney A, Ziegler A, Hermann H, Fichter M, Mayer H, Siegfried W, Young JK, Remschmidt H, Hebebrand J.

J Clin Endocrinol Metab. 1998 Dec;83(12):4524-7.

PMID:
9851804
48.

Interactions between human bronchoepithelial cells and lung fibroblasts after ozone exposure in vitro.

Lang DS, Jörres RA, Mücke M, Siegfried W, Magnussen H.

Toxicol Lett. 1998 Aug;96-97:13-24.

PMID:
9820643
49.

Systematic mutation screening of the pro-opiomelanocortin gene: identification of several genetic variants including three different insertions, one nonsense and two missense point mutations in probands of different weight extremes.

Hinney A, Becker I, Heibült O, Nottebom K, Schmidt A, Ziegler A, Mayer H, Siegfried W, Blum WF, Remschmidt H, Hebebrand J.

J Clin Endocrinol Metab. 1998 Oct;83(10):3737-41.

PMID:
9768693
50.

Analysis of the uncoupling protein-1 (UCP1) gene in obese and lean subjects: identification of four amino acid variants.

Hamann A, Tafel J, Büsing B, Münzberg H, Hinney A, Mayer H, Siegfried W, Ricquier D, Greten H, Hebebrand J, Matthaei S.

Int J Obes Relat Metab Disord. 1998 Sep;22(9):939-41.

PMID:
9756256

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