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[Burnout and Gratification Crises in Female and Male Physicians during Postgraduate Medical Education in Germany - A Longitudinal Study].

Kocalevent RD, Pinnschmidt H, Nehls S, Boczor S, Siegert S, Scherer M, Bussche HVD.

Psychother Psychosom Med Psychol. 2020 Jan 17. doi: 10.1055/a-1068-9843. [Epub ahead of print] German.


Towards Quantification of Inflammation in Atherosclerotic Plaque in the Clinic - Characterization and Optimization of Fluorine-19 MRI in Mice at 3 T.

Darçot E, Colotti R, Pellegrin M, Wilson A, Siegert S, Bouzourene K, Yerly J, Mazzolai L, Stuber M, van Heeswijk RB.

Sci Rep. 2019 Nov 25;9(1):17488. doi: 10.1038/s41598-019-53905-9.


The effects of valbenazine on tardive dyskinesia in older and younger patients.

Sajatovic M, Alexopoulos GS, Burke J, Farahmand K, Siegert S.

Int J Geriatr Psychiatry. 2020 Jan;35(1):69-79. doi: 10.1002/gps.5218. Epub 2019 Oct 31.


Targeting microglia with lentivirus and AAV: Recent advances and remaining challenges.

Maes ME, Colombo G, Schulz R, Siegert S.

Neurosci Lett. 2019 Aug 10;707:134310. doi: 10.1016/j.neulet.2019.134310. Epub 2019 May 31. Review.


Adverse events associated with deep brain stimulation in patients with childhood-onset dystonia.

Koy A, Bockhorn N, Kühn AA, Schneider GH, Krause P, Lauritsch K, Witt K, Paschen S, Deuschl G, Krauss JK, Saryyeva A, Runge J, Borggraefe I, Mehrkens JH, Horn A, Vesper J, Schnitzler A, Siegert S, Freilinger M, Eckenweiler M, Coenen VA, Tadic V, Voges J, Pauls KAM, Wirths J, Timmermann L, Hellmich M; GEPESTIM consortium.

Brain Stimul. 2019 Sep - Oct;12(5):1111-1120. doi: 10.1016/j.brs.2019.04.003. Epub 2019 Apr 13.


Subthalamic and pallidal oscillatory activity in patients with Neurodegeneration with Brain Iron Accumulation type I (NBIA-I).

Huebl J, Poshtiban A, Brücke C, Siegert S, Bock A, Koziara H, Kmiec T, Rola R, Mandat T, Kühn AA.

Clin Neurophysiol. 2019 Apr;130(4):469-473. doi: 10.1016/j.clinph.2018.12.012. Epub 2019 Jan 25.


The effects of valbenazine on tardive dyskinesia in patients with a primary mood disorder.

McIntyre RS, Calabrese JR, Nierenberg AA, Farahmand K, Yonan C, Siegert S, Burke J.

J Affect Disord. 2019 Mar 1;246:217-223. doi: 10.1016/j.jad.2018.12.023. Epub 2018 Dec 17.


[What is Known About the Real Length of Postgraduate Medical Education in Germany?]

van den Bussche H, Nehls S, Boczor S, Siegert S, Kocalevent RD, Scherer M.

Dtsch Med Wochenschr. 2018 Sep;143(18):e152-e158. doi: 10.1055/a-0631-1050. Epub 2018 Sep 10. German.


Suppression of Tcf1 by Inflammatory Cytokines Facilitates Effector CD8 T Cell Differentiation.

Danilo M, Chennupati V, Silva JG, Siegert S, Held W.

Cell Rep. 2018 Feb 20;22(8):2107-2117. doi: 10.1016/j.celrep.2018.01.072.


Dopamine-dependent scaling of subthalamic gamma bursts with movement velocity in patients with Parkinson's disease.

Lofredi R, Neumann WJ, Bock A, Horn A, Huebl J, Siegert S, Schneider GH, Krauss JK, Kühn AA.

Elife. 2018 Feb 1;7. pii: e31895. doi: 10.7554/eLife.31895.


Serum metabolomic profiling highlights pathways associated with liver fat content in a general population sample.

Koch M, Freitag-Wolf S, Schlesinger S, Borggrefe J, Hov JR, Jensen MK, Pick J, Markus MRP, Höpfner T, Jacobs G, Siegert S, Artati A, Kastenmüller G, Römisch-Margl W, Adamski J, Illig T, Nothnagel M, Karlsen TH, Schreiber S, Franke A, Krawczak M, Nöthlings U, Lieb W.

Eur J Clin Nutr. 2017 Aug;71(8):995-1001. doi: 10.1038/ejcn.2017.43. Epub 2017 Apr 5.


[Reliable health information for patients with rare diseases : Quality demands defined by the National Action Plan and how they are put into practice].

Schaefer C, Brunsmann F, Siegert S.

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2017 May;60(5):510-516. doi: 10.1007/s00103-017-2531-z. German.


Notch regulates Th17 differentiation and controls trafficking of IL-17 and metabolic regulators within Th17 cells in a context-dependent manner.

Coutaz M, Hurrell BP, Auderset F, Wang H, Siegert S, Eberl G, Ho PC, Radtke F, Tacchini-Cottier F.

Sci Rep. 2016 Dec 15;6:39117. doi: 10.1038/srep39117.


Meta-Analysis of Genome-Wide Association Studies and Network Analysis-Based Integration with Gene Expression Data Identify New Suggestive Loci and Unravel a Wnt-Centric Network Associated with Dupuytren's Disease.

Becker K, Siegert S, Toliat MR, Du J, Casper R, Dolmans GH, Werker PM, Tinschert S, Franke A, Gieger C, Strauch K, Nothnagel M, Nürnberg P, Hennies HC; German Dupuytren Study Group.

PLoS One. 2016 Jul 28;11(7):e0158101. doi: 10.1371/journal.pone.0158101. eCollection 2016.


AIM2 inflammasome is activated by pharmacological disruption of nuclear envelope integrity.

Di Micco A, Frera G, Lugrin J, Jamilloux Y, Hsu ET, Tardivel A, De Gassart A, Zaffalon L, Bujisic B, Siegert S, Quadroni M, Broz P, Henry T, Hrycyna CA, Martinon F.

Proc Natl Acad Sci U S A. 2016 Aug 9;113(32):E4671-80. doi: 10.1073/pnas.1602419113. Epub 2016 Jul 26.


Addendum: The schizophrenia risk gene product miR-137 alters presynaptic plasticity.

Siegert S, Seo J, Kwon EJ, Rudenko A, Cho S, Wang W, Flood Z, Martorell AJ, Ericsson M, Mungenast AE, Tsai LH.

Nat Neurosci. 2016 Jul 26;19(8):1115. doi: 10.1038/nn0816-1115c. No abstract available.


Treatment of ongoing autoimmune encephalomyelitis with activated B-cell progenitors maturing into regulatory B cells.

Korniotis S, Gras C, Letscher H, Montandon R, Mégret J, Siegert S, Ezine S, Fallon PG, Luther SA, Fillatreau S, Zavala F.

Nat Commun. 2016 Jul 11;7:12134. doi: 10.1038/ncomms12134.


How MicroRNAs Are Involved in Splitting the Mind.

Tsai LH, Siegert S.

JAMA Psychiatry. 2016 Apr;73(4):409-10. doi: 10.1001/jamapsychiatry.2015.3144. No abstract available.


T Cell Priming by Activated Nlrc5-Deficient Dendritic Cells Is Unaffected despite Partially Reduced MHC Class I Levels.

Rota G, Ludigs K, Siegert S, Tardivel A, Morgado L, Reith W, De Gassart A, Guarda G.

J Immunol. 2016 Apr 1;196(7):2939-46. doi: 10.4049/jimmunol.1502084. Epub 2016 Mar 4.


Modeling Alzheimer's disease with human induced pluripotent stem (iPS) cells.

Mungenast AE, Siegert S, Tsai LH.

Mol Cell Neurosci. 2016 Jun;73:13-31. doi: 10.1016/j.mcn.2015.11.010. Epub 2015 Dec 4. Review.


DLL4 promotes continuous adult intestinal lacteal regeneration and dietary fat transport.

Bernier-Latmani J, Cisarovsky C, Demir CS, Bruand M, Jaquet M, Davanture S, Ragusa S, Siegert S, Dormond O, Benedito R, Radtke F, Luther SA, Petrova TV.

J Clin Invest. 2015 Nov 3;125(12):4572-86. doi: 10.1172/JCI82045.


[Patient guidelines in oncology: objectives, procedures and first experiences with this format].

Schaefer C, Zowalla R, Wiesner M, Siegert S, Bothe L, Follmann M.

Z Evid Fortbild Qual Gesundhwes. 2015;109(6):445-51. doi: 10.1016/j.zefq.2015.09.013. Epub 2015 Sep 28. German.


Differential diagnosis of bladder versus colorectal adenocarcinoma: keratin 7 and GATA3 positivity in nuclear ß-catenin-negative glandular tumours defines adenocarcinoma of the bladder.

Broede A, Oll M, Maurer A, Siegert S, Stoerkel S, Golz R, Schwamborn K, Veeck J, Knuechel R, Gaisa NT; German study group of bladder cancers.

J Clin Pathol. 2016 Apr;69(4):307-12. doi: 10.1136/jclinpath-2015-203144. Epub 2015 Oct 13.


Comparison of structural genetics of non-schistosoma-associated squamous cell carcinoma of the urinary bladder.

Molitor M, Junker K, Eltze E, Toma M, Denzinger S, Siegert S, Knuechel R, Gaisa NT.

Int J Clin Exp Pathol. 2015 Jul 1;8(7):8143-58. eCollection 2015.


Mutations Causing Complex Disease May under Certain Circumstances Be Protective in an Epidemiological Sense.

Siegert S, Wolf A, Cooper DN, Krawczak M, Nothnagel M.

PLoS One. 2015 Jul 10;10(7):e0132150. doi: 10.1371/journal.pone.0132150. eCollection 2015.


[Short information leaflets for patients - a service offered to physicians: Early implementation experiences].

Schaefer C, Siegert S, Bothe L, Schwarz S, Ollenschläger G.

Z Evid Fortbild Qual Gesundhwes. 2015;109(2):153-8. doi: 10.1016/j.zefq.2015.03.007. Epub 2015 Apr 25. German.


The schizophrenia risk gene product miR-137 alters presynaptic plasticity.

Siegert S, Seo J, Kwon EJ, Rudenko A, Cho S, Wang W, Flood Z, Martorell AJ, Ericsson M, Mungenast AE, Tsai LH.

Nat Neurosci. 2015 Jul;18(7):1008-16. doi: 10.1038/nn.4023. Epub 2015 May 25. Erratum in: Nat Neurosci. 2016 Jul 26;19(8):1115.


Basolateral amygdala bidirectionally modulates stress-induced hippocampal learning and memory deficits through a p25/Cdk5-dependent pathway.

Rei D, Mason X, Seo J, Gräff J, Rudenko A, Wang J, Rueda R, Siegert S, Cho S, Canter RG, Mungenast AE, Deisseroth K, Tsai LH.

Proc Natl Acad Sci U S A. 2015 Jun 9;112(23):7291-6. doi: 10.1073/pnas.1415845112. Epub 2015 May 20.


Incidence and natural history of challenge-proven cow's milk allergy in European children--EuroPrevall birth cohort.

Schoemaker AA, Sprikkelman AB, Grimshaw KE, Roberts G, Grabenhenrich L, Rosenfeld L, Siegert S, Dubakiene R, Rudzeviciene O, Reche M, Fiandor A, Papadopoulos NG, Malamitsi-Puchner A, Fiocchi A, Dahdah L, Sigurdardottir ST, Clausen M, Stańczyk-Przyłuska A, Zeman K, Mills EN, McBride D, Keil T, Beyer K.

Allergy. 2015 Aug;70(8):963-72. doi: 10.1111/all.12630. Epub 2015 May 18.


Shannon's equivocation for forensic Y-STR marker selection.

Siegert S, Roewer L, Nothnagel M.

Forensic Sci Int Genet. 2015 May;16:216-225. doi: 10.1016/j.fsigen.2015.02.001. Epub 2015 Feb 9.


Comparison of two exploratory dietary patterns in association with the metabolic syndrome in a Northern German population.

Barbaresko J, Siegert S, Koch M, Aits I, Lieb W, Nikolaus S, Laudes M, Jacobs G, Nöthlings U.

Br J Nutr. 2014 Oct 28;112(8):1364-72. doi: 10.1017/S0007114514002098.


Postdiagnosis body mass index and risk of mortality in colorectal cancer survivors: a prospective study and meta-analysis.

Schlesinger S, Siegert S, Koch M, Walter J, Heits N, Hinz S, Jacobs G, Hampe J, Schafmayer C, Nöthlings U.

Cancer Causes Control. 2014 Oct;25(10):1407-18. doi: 10.1007/s10552-014-0435-x. Epub 2014 Jul 19.


A global analysis of Y-chromosomal haplotype diversity for 23 STR loci.

Purps J, Siegert S, Willuweit S, Nagy M, Alves C, Salazar R, Angustia SM, Santos LH, Anslinger K, Bayer B, Ayub Q, Wei W, Xue Y, Tyler-Smith C, Bafalluy MB, Martínez-Jarreta B, Egyed B, Balitzki B, Tschumi S, Ballard D, Court DS, Barrantes X, Bäßler G, Wiest T, Berger B, Niederstätter H, Parson W, Davis C, Budowle B, Burri H, Borer U, Koller C, Carvalho EF, Domingues PM, Chamoun WT, Coble MD, Hill CR, Corach D, Caputo M, D'Amato ME, Davison S, Decorte R, Larmuseau MH, Ottoni C, Rickards O, Lu D, Jiang C, Dobosz T, Jonkisz A, Frank WE, Furac I, Gehrig C, Castella V, Grskovic B, Haas C, Wobst J, Hadzic G, Drobnic K, Honda K, Hou Y, Zhou D, Li Y, Hu S, Chen S, Immel UD, Lessig R, Jakovski Z, Ilievska T, Klann AE, García CC, de Knijff P, Kraaijenbrink T, Kondili A, Miniati P, Vouropoulou M, Kovacevic L, Marjanovic D, Lindner I, Mansour I, Al-Azem M, Andari AE, Marino M, Furfuro S, Locarno L, Martín P, Luque GM, Alonso A, Miranda LS, Moreira H, Mizuno N, Iwashima Y, Neto RS, Nogueira TL, Silva R, Nastainczyk-Wulf M, Edelmann J, Kohl M, Nie S, Wang X, Cheng B, Núñez C, Pancorbo MM, Olofsson JK, Morling N, Onofri V, Tagliabracci A, Pamjav H, Volgyi A, Barany G, Pawlowski R, Maciejewska A, Pelotti S, Pepinski W, Abreu-Glowacka M, Phillips C, Cárdenas J, Rey-Gonzalez D, Salas A, Brisighelli F, Capelli C, Toscanini U, Piccinini A, Piglionica M, Baldassarra SL, Ploski R, Konarzewska M, Jastrzebska E, Robino C, Sajantila A, Palo JU, Guevara E, Salvador J, Ungria MC, Rodriguez JJ, Schmidt U, Schlauderer N, Saukko P, Schneider PM, Sirker M, Shin KJ, Oh YN, Skitsa I, Ampati A, Smith TG, Calvit LS, Stenzl V, Capal T, Tillmar A, Nilsson H, Turrina S, De Leo D, Verzeletti A, Cortellini V, Wetton JH, Gwynne GM, Jobling MA, Whittle MR, Sumita DR, Wolańska-Nowak P, Yong RY, Krawczak M, Nothnagel M, Roewer L.

Forensic Sci Int Genet. 2014 Sep;12:12-23. doi: 10.1016/j.fsigen.2014.04.008. Epub 2014 Apr 28.


Improved predictions of rare events using the Crooks fluctuation theorem.

Gundermann J, Siegert S, Kantz H.

Phys Rev E Stat Nonlin Soft Matter Phys. 2014 Mar;89(3):032112. Epub 2014 Mar 12.


Error signals in the subthalamic nucleus are related to post-error slowing in patients with Parkinson's disease.

Siegert S, Herrojo Ruiz M, Brücke C, Huebl J, Schneider GH, Ullsperger M, Kühn AA.

Cortex. 2014 Nov;60:103-20. doi: 10.1016/j.cortex.2013.12.008. Epub 2014 Jan 10.


Dietary patterns associated with magnetic resonance imaging-determined liver fat content in a general population study.

Koch M, Borggrefe J, Barbaresko J, Groth G, Jacobs G, Siegert S, Lieb W, Müller MJ, Bosy-Westphal A, Heller M, Nöthlings U.

Am J Clin Nutr. 2014 Feb;99(2):369-77. doi: 10.3945/ajcn.113.070219. Epub 2013 Dec 4.


Results of a prospective study comparing the clinical efficacy of cryoablation of renal cell cancer followed by immediate partial nephrectomy.

Khoder WY, Siegert S, Stief CG, Becker AJ, Waidelich R.

Eur J Surg Oncol. 2014 Jan;40(1):96-102. doi: 10.1016/j.ejso.2013.09.025. Epub 2013 Oct 6.


Diagnosing fatty liver disease: a comparative evaluation of metabolic markers, phenotypes, genotypes and established biomarkers.

Siegert S, Yu Z, Wang-Sattler R, Illig T, Adamski J, Hampe J, Nikolaus S, Schreiber S, Krawczak M, Nothnagel M, Nöthlings U.

PLoS One. 2013 Oct 9;8(10):e76813. doi: 10.1371/journal.pone.0076813. eCollection 2013.


Innate signaling promotes formation of regulatory nitric oxide-producing dendritic cells limiting T-cell expansion in experimental autoimmune myocarditis.

Kania G, Siegert S, Behnke S, Prados-Rosales R, Casadevall A, Lüscher TF, Luther SA, Kopf M, Eriksson U, Blyszczuk P.

Circulation. 2013 Jun 11;127(23):2285-94. doi: 10.1161/CIRCULATIONAHA.112.000434. Epub 2013 May 13.


[Metastases in patients with breast cancer despite of negative sentinel lymph node. Has the concept to be changed?].

Weiss M, Meyer M, Siegert S, Bartenstein P, Pfluger T.

Nuklearmedizin. 2013;52(1):14-20. doi: 10.3413/Nukmed-0535-12-10. Epub 2013 Feb 7. German.


Multimodality treatment for early-stage hepatocellular carcinoma: a bridging therapy for liver transplantation.

Ashoori N, Bamberg F, Paprottka P, Rentsch M, Kolligs FT, Siegert S, Peporte A, Al-Tubaikh JA, D'Anastasi M, Hoffmann RT, Reiser MF, Jakobs TF.

Digestion. 2012;86(4):338-48. doi: 10.1159/000342813. Epub 2012 Nov 28.


Genome-wide investigation of gene-environment interactions in colorectal cancer.

Siegert S, Hampe J, Schafmayer C, von Schönfels W, Egberts JH, Försti A, Chen B, Lascorz J, Hemminki K, Franke A, Nothnagel M, Nöthlings U, Krawczak M.

Hum Genet. 2013 Feb;132(2):219-31. doi: 10.1007/s00439-012-1239-2. Epub 2012 Nov 2.


Prognostic value of perinodal lymphovascular invasion following radical cystectomy for lymph node-positive urothelial carcinoma.

Fritsche HM, May M, Denzinger S, Otto W, Siegert S, Giedl C, Giedl J, Eder F, Agaimy A, Novotny V, Wirth M, Stief C, Brookman-May S, Hofstädter F, Gierth M, Aziz A, Kocot A, Riedmiller H, Bastian PJ, Toma M, Wieland WF, Hartmann A, Burger M.

Eur Urol. 2013 Apr;63(4):739-44. doi: 10.1016/j.eururo.2012.09.053. Epub 2012 Sep 28.


Positive and negative regulation of T cell responses by fibroblastic reticular cells within paracortical regions of lymph nodes.

Siegert S, Luther SA.

Front Immunol. 2012 Sep 11;3:285. doi: 10.3389/fimmu.2012.00285. eCollection 2012.


Dual energy CT in patients with polycystic kidney disease.

Arndt N, Staehler M, Siegert S, Reiser MF, Graser A.

Eur Radiol. 2012 Oct;22(10):2125-9. doi: 10.1007/s00330-012-2481-7. Epub 2012 May 17.


Transcriptional code and disease map for adult retinal cell types.

Siegert S, Cabuy E, Scherf BG, Kohler H, Panda S, Le YZ, Fehling HJ, Gaidatzis D, Stadler MB, Roska B.

Nat Neurosci. 2012 Jan 22;15(3):487-95, S1-2. doi: 10.1038/nn.3032.


Outcome of laser-assisted laparoscopic partial nephrectomy without ischaemia for peripheral renal tumours.

Khoder WY, Sroka R, Siegert S, Stief CG, Becker AJ.

World J Urol. 2012 Oct;30(5):633-8. doi: 10.1007/s00345-011-0807-8. Epub 2011 Dec 13.


Fibroblastic reticular cells from lymph nodes attenuate T cell expansion by producing nitric oxide.

Siegert S, Huang HY, Yang CY, Scarpellino L, Carrie L, Essex S, Nelson PJ, Heikenwalder M, Acha-Orbea H, Buckley CD, Marsland BJ, Zehn D, Luther SA.

PLoS One. 2011;6(11):e27618. doi: 10.1371/journal.pone.0027618. Epub 2011 Nov 14.


Transcript signature predicts tissue NK cell content and defines renal cell carcinoma subgroups independent of TNM staging.

Eckl J, Buchner A, Prinz PU, Riesenberg R, Siegert SI, Kammerer R, Nelson PJ, Noessner E.

J Mol Med (Berl). 2012 Jan;90(1):55-66. doi: 10.1007/s00109-011-0806-7. Epub 2011 Aug 26.


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