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The Modified Lepird Procedure for Correction of Metatarsus Adductus.

Siegel SJ.

J Foot Ankle Surg. 2019 Jul 23. pii: S1067-2516(18)30589-1. doi: 10.1053/j.jfas.2018.12.033. [Epub ahead of print]


High-beta/low-gamma frequency activity reflects top-down predictive coding during a spatial working memory test.

Zhang RV, Featherstone RE, Melynchenko O, Gifford R, Weger R, Liang Y, Siegel SJ.

Exp Brain Res. 2019 Jul;237(7):1881-1888. doi: 10.1007/s00221-019-05558-3. Epub 2019 May 15.


Src deficient mice demonstrate behavioral and electrophysiological alterations relevant to psychiatric and developmental disease.

Ward KR, Featherstone RE, Naschek MJ, Melnychenko O, Banerjee A, Yi J, Gifford RL, Borgmann-Winter KE, Salter MW, Hahn CG, Siegel SJ.

Prog Neuropsychopharmacol Biol Psychiatry. 2019 Jul 13;93:84-92. doi: 10.1016/j.pnpbp.2019.02.017. Epub 2019 Feb 28.


Parvalbumin Cell Ablation of NMDA-R1 Leads to Altered Phase, But Not Amplitude, of Gamma-Band Cross-Frequency Coupling.

Port RG, Berman JI, Liu S, Featherstone RE, Roberts TPL, Siegel SJ.

Brain Connect. 2019 Apr;9(3):263-272. doi: 10.1089/brain.2018.0639. Epub 2019 Mar 15.


mGluR5 hypofunction is integral to glutamatergic dysregulation in schizophrenia.

Wang HY, MacDonald ML, Borgmann-Winter KE, Banerjee A, Sleiman P, Tom A, Khan A, Lee KC, Roussos P, Siegel SJ, Hemby SE, Bilker WB, Gur RE, Hahn CG.

Mol Psychiatry. 2018 Sep 13. doi: 10.1038/s41380-018-0234-y. [Epub ahead of print]


Pyramidal cell-selective GluN1 knockout causes impairments in salience attribution and related EEG activity.

Forrest AD, Bang J, Featherstone RE, Bloom JH, Luminais MS, Zhang RV, Gajewski CR, McMullen MF, Liang Y, Siegel SJ.

Exp Brain Res. 2018 Mar;236(3):837-846. doi: 10.1007/s00221-017-5152-8. Epub 2018 Jan 19.


Protocadherin 10 alters γ oscillations, amino acid levels, and their coupling; baclofen partially restores these oscillatory deficits.

Port RG, Gajewski C, Krizman E, Dow HC, Hirano S, Brodkin ES, Carlson GC, Robinson MB, Roberts TPL, Siegel SJ.

Neurobiol Dis. 2017 Dec;108:324-338. doi: 10.1016/j.nbd.2017.08.013. Epub 2017 Aug 24.


Mismatch negativity in preclinical models of schizophrenia.

Featherstone RE, Melnychenko O, Siegel SJ.

Schizophr Res. 2018 Jan;191:35-42. doi: 10.1016/j.schres.2017.07.039. Epub 2017 Jul 30. Review.


GABA-B Agonist Baclofen Normalizes Auditory-Evoked Neural Oscillations and Behavioral Deficits in the Fmr1 Knockout Mouse Model of Fragile X Syndrome.

Sinclair D, Featherstone R, Naschek M, Nam J, Du A, Wright S, Pance K, Melnychenko O, Weger R, Akuzawa S, Matsumoto M, Siegel SJ.

eNeuro. 2017 Mar 1;4(1). pii: ENEURO.0380-16.2017. doi: 10.1523/ENEURO.0380-16.2017. eCollection 2017 Jan-Feb.


Amygdala activity associated with social choice in mice.

Mihara T, Mensah-Brown K, Sobota R, Lin R, Featherstone R, Siegel SJ.

Behav Brain Res. 2017 Aug 14;332:84-89. doi: 10.1016/j.bbr.2017.04.040. Epub 2017 Apr 21.


Metabotropic Glutamate Receptor 5 as a Point of Convergence for Models of Obsessive-Compulsive Disorder and Autism Spectrum Disorder.

Matosin N, Siegel SJ.

Biol Psychiatry. 2016 Oct 1;80(7):504-6. doi: 10.1016/j.biopsych.2016.08.005. No abstract available.


Multiple Drug Treatments That Increase cAMP Signaling Restore Long-Term Memory and Aberrant Signaling in Fragile X Syndrome Models.

Choi CH, Schoenfeld BP, Bell AJ, Hinchey J, Rosenfelt C, Gertner MJ, Campbell SR, Emerson D, Hinchey P, Kollaros M, Ferrick NJ, Chambers DB, Langer S, Sust S, Malik A, Terlizzi AM, Liebelt DA, Ferreiro D, Sharma A, Koenigsberg E, Choi RJ, Louneva N, Arnold SE, Featherstone RE, Siegel SJ, Zukin RS, McDonald TV, Bolduc FV, Jongens TA, McBride SM.

Front Behav Neurosci. 2016 Jun 30;10:136. doi: 10.3389/fnbeh.2016.00136. eCollection 2016.


Sensory processing in autism spectrum disorders and Fragile X syndrome-From the clinic to animal models.

Sinclair D, Oranje B, Razak KA, Siegel SJ, Schmid S.

Neurosci Biobehav Rev. 2017 May;76(Pt B):235-253. doi: 10.1016/j.neubiorev.2016.05.029. Epub 2016 May 24. Review.


Lysosomal iron modulates NMDA receptor-mediated excitation via small GTPase, Dexras1.

White RS, Bhattacharya AK, Chen Y, Byrd M, McMullen MF, Siegel SJ, Carlson GC, Kim SF.

Mol Brain. 2016 Apr 14;9:38. doi: 10.1186/s13041-016-0220-8.


Dexras1 a unique ras-GTPase interacts with NMDA receptor activity and provides a novel dissociation between anxiety, working memory and sensory gating.

Carlson GC, Lin RE, Chen Y, Brookshire BR, White RS, Lucki I, Siegel SJ, Kim SF.

Neuroscience. 2016 May 13;322:408-15. doi: 10.1016/j.neuroscience.2016.02.063. Epub 2016 Mar 3.


Mouse Model of Chromosome 15q13.3 Microdeletion Syndrome Demonstrates Features Related to Autism Spectrum Disorder.

Kogan JH, Gross AK, Featherstone RE, Shin R, Chen Q, Heusner CL, Adachi M, Lin A, Walton NM, Miyoshi S, Miyake S, Tajinda K, Ito H, Siegel SJ, Matsumoto M.

J Neurosci. 2015 Dec 9;35(49):16282-94. doi: 10.1523/JNEUROSCI.3967-14.2015.


Cellular and circuit models of increased resting-state network gamma activity in schizophrenia.

White RS, Siegel SJ.

Neuroscience. 2016 May 3;321:66-76. doi: 10.1016/j.neuroscience.2015.11.011. Epub 2015 Nov 11. Review.


Mechanisms of Bacterial Colonization of the Respiratory Tract.

Siegel SJ, Weiser JN.

Annu Rev Microbiol. 2015;69:425-44. doi: 10.1146/annurev-micro-091014-104209. Review.


The Role of Nicotine in Schizophrenia.

Featherstone RE, Siegel SJ.

Int Rev Neurobiol. 2015;124:23-78. doi: 10.1016/bs.irn.2015.07.002. Epub 2015 Aug 21. Review.


Ceftriaxone reverses ketamine-induced lasting EEG and astrocyte alterations in juvenile mice.

Dodman K, Featherstone RE, Bang J, Liang Y, Siegel SJ.

Drug Alcohol Depend. 2015 Nov 1;156:14-20. doi: 10.1016/j.drugalcdep.2015.07.1198. Epub 2015 Sep 21.


Delayed emergence of behavioral and electrophysiological effects following juvenile ketamine exposure in mice.

Nagy LR, Featherstone RE, Hahn CG, Siegel SJ.

Transl Psychiatry. 2015 Sep 15;5:e635. doi: 10.1038/tp.2015.111.


Oxytocin reduces amygdala activity, increases social interactions, and reduces anxiety-like behavior irrespective of NMDAR antagonism.

Sobota R, Mihara T, Forrest A, Featherstone RE, Siegel SJ.

Behav Neurosci. 2015 Aug;129(4):389-98. doi: 10.1037/bne0000074.


Clearance of Pneumococcal Colonization in Infants Is Delayed through Altered Macrophage Trafficking.

Siegel SJ, Tamashiro E, Weiser JN.

PLoS Pathog. 2015 Jun 24;11(6):e1005004. doi: 10.1371/journal.ppat.1005004. eCollection 2015 Jun.


EEG biomarkers of target engagement, therapeutic effect, and disease process.

Featherstone RE, McMullen MF, Ward KR, Bang J, Xiao J, Siegel SJ.

Ann N Y Acad Sci. 2015 May;1344:12-26. doi: 10.1111/nyas.12745. Epub 2015 Mar 30.


Prospective MEG biomarkers in ASD: pre-clinical evidence and clinical promise of electrophysiological signatures.

Port RG, Anwar AR, Ku M, Carlson GC, Siegel SJ, Roberts TP.

Yale J Biol Med. 2015 Mar 4;88(1):25-36. eCollection 2015 Mar. Review.


PDE-4 inhibition rescues aberrant synaptic plasticity in Drosophila and mouse models of fragile X syndrome.

Choi CH, Schoenfeld BP, Weisz ED, Bell AJ, Chambers DB, Hinchey J, Choi RJ, Hinchey P, Kollaros M, Gertner MJ, Ferrick NJ, Terlizzi AM, Yohn N, Koenigsberg E, Liebelt DA, Zukin RS, Woo NH, Tranfaglia MR, Louneva N, Arnold SE, Siegel SJ, Bolduc FV, McDonald TV, Jongens TA, McBride SM.

J Neurosci. 2015 Jan 7;35(1):396-408. doi: 10.1523/JNEUROSCI.1356-12.2015.


Convergence of circuit dysfunction in ASD: a common bridge between diverse genetic and environmental risk factors and common clinical electrophysiology.

Port RG, Gandal MJ, Roberts TP, Siegel SJ, Carlson GC.

Front Cell Neurosci. 2014 Dec 8;8:414. doi: 10.3389/fncel.2014.00414. eCollection 2014. Review.


[Ketamine alters socially-evoked activity in the amygdala].

Mihara T, Siegel SJ.

Nihon Yakurigaku Zasshi. 2014 Dec;144(6):272-6. Japanese. No abstract available.


Mice with subtle reduction of NMDA NR1 receptor subunit expression have a selective decrease in mismatch negativity: Implications for schizophrenia prodromal population.

Featherstone RE, Shin R, Kogan JH, Liang Y, Matsumoto M, Siegel SJ.

Neurobiol Dis. 2015 Jan;73:289-95. doi: 10.1016/j.nbd.2014.10.010. Epub 2014 Oct 22.


Src kinase as a mediator of convergent molecular abnormalities leading to NMDAR hypoactivity in schizophrenia.

Banerjee A, Wang HY, Borgmann-Winter KE, MacDonald ML, Kaprielian H, Stucky A, Kvasic J, Egbujo C, Ray R, Talbot K, Hemby SE, Siegel SJ, Arnold SE, Sleiman P, Chang X, Hakonarson H, Gur RE, Hahn CG.

Mol Psychiatry. 2015 Sep;20(9):1091-100. doi: 10.1038/mp.2014.115. Epub 2014 Oct 21.


Animal Models of Psychosis: Current State and Future Directions.

Forrest AD, Coto CA, Siegel SJ.

Curr Behav Neurosci Rep. 2014 Jun 1;1(2):100-116.


TLR2 signaling decreases transmission of Streptococcus pneumoniae by limiting bacterial shedding in an infant mouse Influenza A co-infection model.

Richard AL, Siegel SJ, Erikson J, Weiser JN.

PLoS Pathog. 2014 Aug 28;10(8):e1004339. doi: 10.1371/journal.ppat.1004339. eCollection 2014 Aug.


Pyramidal cell selective ablation of N-methyl-D-aspartate receptor 1 causes increase in cellular and network excitability.

Tatard-Leitman VM, Jutzeler CR, Suh J, Saunders JA, Billingslea EN, Morita S, White R, Featherstone RE, Ray R, Ortinski PI, Banerjee A, Gandal MJ, Lin R, Alexandrescu A, Liang Y, Gur RE, Borgmann-Winter KE, Carlson GC, Hahn CG, Siegel SJ.

Biol Psychiatry. 2015 Mar 15;77(6):556-68. doi: 10.1016/j.biopsych.2014.06.026. Epub 2014 Jul 18.


Influenza promotes pneumococcal growth during coinfection by providing host sialylated substrates as a nutrient source.

Siegel SJ, Roche AM, Weiser JN.

Cell Host Microbe. 2014 Jul 9;16(1):55-67. doi: 10.1016/j.chom.2014.06.005.


Cellular origins of auditory event-related potential deficits in Rett syndrome.

Goffin D, Brodkin ES, Blendy JA, Siegel SJ, Zhou Z.

Nat Neurosci. 2014 Jun;17(6):804-6. doi: 10.1038/nn.3710. Epub 2014 Apr 28.


Parvalbumin cell ablation of NMDA-R1 causes increased resting network excitability with associated social and self-care deficits.

Billingslea EN, Tatard-Leitman VM, Anguiano J, Jutzeler CR, Suh J, Saunders JA, Morita S, Featherstone RE, Ortinski PI, Gandal MJ, Lin R, Liang Y, Gur RE, Carlson GC, Hahn CG, Siegel SJ.

Neuropsychopharmacology. 2014 Jun;39(7):1603-13. doi: 10.1038/npp.2014.7. Epub 2014 Feb 14.


Options for the Medical Treatment of Peyronie's Disease.

Levine LA, Siegel SJ.

Rev Urol. 2014;16 Suppl 1:S1-5. No abstract available.


Electroencephalographic and early communicative abnormalities in Brattleboro rats.

Lin RE, Ambler L, Billingslea EN, Suh J, Batheja S, Tatard-Leitman V, Featherstone RE, Siegel SJ.

Physiol Rep. 2013 Oct;1(5):e00100. doi: 10.1002/phy2.100. Epub 2013 Oct 20.


Juvenile exposure to ketamine causes delayed emergence of EEG abnormalities during adulthood in mice.

Featherstone RE, Nagy LR, Hahn CG, Siegel SJ.

Drug Alcohol Depend. 2014 Jan 1;134:123-127. doi: 10.1016/j.drugalcdep.2013.09.017. Epub 2013 Sep 27.


Capacity, confidentiality and consequences: balancing responsible medical care with mental health law.

Siegel SJ.

Curr Psychiatry Rep. 2013 Aug;15(8):380. doi: 10.1007/s11920-013-0380-5. No abstract available.


Neuropsychological correlates of transcription factor AP-2Beta, and its interaction with COMT and MAOA in healthy females.

Schabram I, Eggermann T, Siegel SJ, Gründer G, Zerres K, Vernaleken I.

Neuropsychobiology. 2013;68(2):79-90. doi: 10.1159/000350997. Epub 2013 Jul 19.


Animal models and measures of perceptual processing in schizophrenia.

Siegel SJ, Talpos JC, Geyer MA.

Neurosci Biobehav Rev. 2013 Nov;37(9 Pt B):2092-8. doi: 10.1016/j.neubiorev.2013.06.016. Epub 2013 Jul 15. Review.


The Drosophila DmGluRA is required for social interaction and memory.

Schoenfeld BP, Choi RJ, Choi CH, Terlizzi AM, Hinchey P, Kollaros M, Ferrick NJ, Koenigsberg E, Ferreiro D, Leibelt DA, Siegel SJ, Bell AJ, McDonald TV, Jongens TA, McBride SM.

Front Pharmacol. 2013 May 23;4:64. doi: 10.3389/fphar.2013.00064. eCollection 2013.


The scent of salience--is there olfactory-trigeminal conditioning in humans?

Moessnang C, Pauly K, Kellermann T, Krämer J, Finkelmeyer A, Hummel T, Siegel SJ, Schneider F, Habel U.

Neuroimage. 2013 Aug 15;77:93-104. doi: 10.1016/j.neuroimage.2013.03.049. Epub 2013 Apr 2.


Knockout of NMDA receptors in parvalbumin interneurons recreates autism-like phenotypes.

Saunders JA, Tatard-Leitman VM, Suh J, Billingslea EN, Roberts TP, Siegel SJ.

Autism Res. 2013 Apr;6(2):69-77. doi: 10.1002/aur.1264. Epub 2013 Feb 25.


Electrophysiological and behavioral responses to ketamine in mice with reduced Akt1 expression.

Featherstone RE, M Tatard-Leitman V, Suh JD, Lin R, Lucki I, Siegel SJ.

Psychopharmacology (Berl). 2013 Jun;227(4):639-49. doi: 10.1007/s00213-013-2997-9. Epub 2013 Feb 8.


Loss of CDKL5 disrupts kinome profile and event-related potentials leading to autistic-like phenotypes in mice.

Wang IT, Allen M, Goffin D, Zhu X, Fairless AH, Brodkin ES, Siegel SJ, Marsh ED, Blendy JA, Zhou Z.

Proc Natl Acad Sci U S A. 2012 Dec 26;109(52):21516-21. doi: 10.1073/pnas.1216988110. Epub 2012 Dec 10.


Electroencephalographic changes following direct current deep brain stimulation of auditory cortex: a new model for investigating neuromodulation.

De Rojas JO, Saunders JA, Luminais C, Hamilton RH, Siegel SJ.

Neurosurgery. 2013 Feb;72(2):267-75; discussion 275. doi: 10.1227/NEU.0b013e31827b93c0.


Delivery systems and dosing for antipsychotics.

Rabin CR, Siegel SJ.

Handb Exp Pharmacol. 2012;(212):267-98. doi: 10.1007/978-3-642-25761-2_11. Review.


Nicotine receptor subtype-specific effects on auditory evoked oscillations and potentials.

Featherstone RE, Phillips JM, Thieu T, Ehrlichman RS, Halene TB, Leiser SC, Christian E, Johnson E, Lerman C, Siegel SJ.

PLoS One. 2012;7(7):e39775. doi: 10.1371/journal.pone.0039775. Epub 2012 Jul 20.

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