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Items: 1 to 50 of 125

1.

The maximal cytoprotective function of the heat shock protein 27 is dependent on heat shock protein 70.

Sreedharan R, Riordan M, Thullin G, Van Why S, Siegel NJ, Kashgarian M.

Biochim Biophys Acta. 2011 Jan;1813(1):129-35. doi: 10.1016/j.bbamcr.2010.08.012. Epub 2010 Oct 8.

2.

Modulation of renal cell injury by heat shock proteins: lessons learned from the immature kidney.

Riordan M, Sreedharan R, Kashgarian M, Siegel NJ.

Nat Clin Pract Nephrol. 2006 Mar;2(3):149-56. Review.

PMID:
16932413
3.

Steroid resistance in childhood nephrotic syndrome.

Berns JS, Siegel NJ.

Kidney Int. 2006 May;69(10):1915-6. No abstract available.

4.

Report of an NIH task force on research priorities in chronic kidney disease in children.

Chesney RW, Brewer E, Moxey-Mims M, Watkins S, Furth SL, Harmon WE, Fine RN, Portman RJ, Warady BA, Salusky IB, Langman CB, Gipson D, Scheidt P, Feldman H, Kaskel FJ, Siegel NJ.

Pediatr Nephrol. 2006 Jan;21(1):14-25. Epub 2005 Oct 27. No abstract available.

PMID:
16252095
5.

HSP70 binding modulates detachment of Na-K-ATPase following energy deprivation in renal epithelial cells.

Riordan M, Sreedharan R, Wang S, Thulin G, Mann A, Stankewich M, Van Why S, Kashgarian M, Siegel NJ.

Am J Physiol Renal Physiol. 2005 Jun;288(6):F1236-42. Epub 2005 Feb 8.

6.

Reduced tolerance of immature renal tubules to anoxia by HSF-1 decoy.

Sreedharan R, Riordan M, Wang S, Thulin G, Kashgarian M, Siegel NJ.

Am J Physiol Renal Physiol. 2005 Feb;288(2):F322-6. Epub 2004 Oct 5.

7.

Differential inhibition of HSP72 and HSP25 produces profound impairment of cellular integrity.

Riordan M, Garg V, Thulin G, Kashgarian M, Siegel NJ.

J Am Soc Nephrol. 2004 Jun;15(6):1557-66.

8.

The risk of cardiovascular disease in adults who have had childhood nephrotic syndrome.

Lechner BL, Bockenhauer D, Iragorri S, Kennedy TL, Siegel NJ.

Pediatr Nephrol. 2004 Jul;19(7):744-8. Epub 2004 Apr 15.

PMID:
15085419
9.

2003 Presidential Address: A time for morphogenesis, growth, and development.

Siegel NJ.

J Am Soc Nephrol. 2004 Apr;15(4):839-43. No abstract available.

10.

Acute renal failure: directions for the next decade.

Siegel NJ, Shah SV.

J Am Soc Nephrol. 2003 Aug;14(8):2176-7. No abstract available.

11.

American Pediatric Society John Howland Award 2002: presentation.

Siegel NJ.

Pediatr Res. 2003 Mar;53(3):526-8. No abstract available.

PMID:
12595607
12.

Developmental expression of HSP-72 and ischemic tolerance of the immature kidney.

Vicencio A, Bidmon B, Ryu J, Reidy K, Thulin G, Mann A, Gaudio KM, Kashgarian M, Siegel NJ.

Pediatr Nephrol. 2003 Feb;18(2):85-91. Epub 2002 Nov 22.

PMID:
12579393
13.

Hsp27 associates with actin and limits injury in energy depleted renal epithelia.

Van Why SK, Mann AS, Ardito T, Thulin G, Ferris S, Macleod MA, Kashgarian M, Siegel NJ.

J Am Soc Nephrol. 2003 Jan;14(1):98-106.

14.

Ischemic conditioning prevents Na,K-ATPase dissociation from the cytoskeletal cellular fraction after repeat renal ischemia in rats.

Aufricht C, Bidmon B, Ruffingshofer D, Regele H, Herkner K, Siegel NJ, Kashgarian M, Van Why SK.

Pediatr Res. 2002 Jun;51(6):722-7.

PMID:
12032267
15.

Clinical course and outcome for children with multicystic dysplastic kidneys.

Feldenberg LR, Siegel NJ.

Pediatr Nephrol. 2000 Oct;14(12):1098-101.

PMID:
11045394
16.

Thresholds for cellular disruption and activation of the stress response in renal epithelia.

van Why SK, Kim S, Geibel J, Seebach FA, Kashgarian M, Siegel NJ.

Am J Physiol. 1999 Aug;277(2):F227-34. doi: 10.1152/ajprenal.1999.277.2.F227.

PMID:
10444577
17.

Expression and role of parathyroid hormone-related protein in human renal proximal tubule cells during recovery from ATP depletion.

García-Ocaña A, Galbraith SC, Van Why SK, Yang K, Golovyan L, Dann P, Zager RA, Stewart AF, Siegel NJ, Orloff JJ.

J Am Soc Nephrol. 1999 Feb;10(2):238-44.

18.

Role of heat stress response in the tolerance of immature renal tubules to anoxia.

Gaudio KM, Thulin G, Mann A, Kashgarian M, Siegel NJ.

Am J Physiol. 1998 Jun;274(6):F1029-36. doi: 10.1152/ajprenal.1998.274.6.F1029.

PMID:
9841493
19.

Heat shock proteins in renal injury and recovery.

Van Why SK, Siegel NJ.

Curr Opin Nephrol Hypertens. 1998 Jul;7(4):407-12. Review.

PMID:
9690040
20.

ATP releases HSP-72 from protein aggregates after renal ischemia.

Aufricht C, Lu E, Thulin G, Kashgarian M, Siegel NJ, Van Why SK.

Am J Physiol. 1998 Feb;274(2):F268-74. doi: 10.1152/ajprenal.1998.274.2.F268.

PMID:
9486221
21.

Heat-shock protein 25 induction and redistribution during actin reorganization after renal ischemia.

Aufricht C, Ardito T, Thulin G, Kashgarian M, Siegel NJ, Van Why SK.

Am J Physiol. 1998 Jan;274(1):F215-22. doi: 10.1152/ajprenal.1998.274.1.F215.

PMID:
9458842
22.

Immature tubules are tolerant of oxygen deprivation.

Gaudio KM, Thulin G, Siegel NJ.

Pediatr Nephrol. 1997 Dec;11(6):757-60. Review.

PMID:
9438661
23.

Severe hypertension without urinary abnormalities in a patient with Henoch-Schönlein purpura.

Whyte DA, Van Why SK, Siegel NJ.

Pediatr Nephrol. 1997 Dec;11(6):750-1.

PMID:
9438659
24.

Acute renal failure in the 21st century: recommendations for management and outcomes assessment.

DuBose TD Jr, Warnock DG, Mehta RL, Bonventre JV, Hammerman MR, Molitoris BA, Paller MS, Siegel NJ, Scherbenske J, Striker GE.

Am J Kidney Dis. 1997 May;29(5):793-9. Review.

PMID:
9159318
25.

Glycolysis is not responsible for the tolerance of immature renal tubules to anoxia.

Gaudio KM, Thulin G, Siegel NJ.

Pediatr Res. 1996 Sep;40(3):457-61.

PMID:
8865284
26.

Activation of heat-shock transcription factor by graded reductions in renal ATP, in vivo, in the rat.

Van Why SK, Mann AS, Thulin G, Zhu XH, Kashgarian M, Siegel NJ.

J Clin Invest. 1994 Oct;94(4):1518-23.

27.

An unusual skin lesion in a pediatric patient with Wegener's granulomatosis.

McKenney DW, Siegel NJ.

Pediatr Nephrol. 1994 Oct;8(5):587-8.

PMID:
7819007
28.

Renal cell injury: metabolic and structural alterations.

Siegel NJ, Devarajan P, Van Why S.

Pediatr Res. 1994 Aug;36(2):129-36. Review. No abstract available.

PMID:
7970927
29.

Expression and molecular regulation of Na(+)-K(+)-ATPase after renal ischemia.

Van Why SK, Mann AS, Ardito T, Siegel NJ, Kashgarian M.

Am J Physiol. 1994 Jul;267(1 Pt 2):F75-85.

PMID:
8048568
30.

Immature renal tubules are resistant to prolonged anoxia.

Gaudio KM, Thulin G, Ardito T, Kashgarian M, Siegel NJ.

Pediatr Res. 1994 Feb;35(2):152-6.

PMID:
8165048
31.

Altered renovascular resistance after spontaneous recovery from hemolytic uremic syndrome.

O'Brien JA, Van Why SK, Keller MS, Gaudio KM, Kennedy TL, Siegel NJ.

Yale J Biol Med. 1994 Jan-Apr;67(1-2):1-14. Review.

32.

Expression of parathyroid hormone-related protein in the rat glomerulus and tubule during recovery from renal ischemia.

Soifer NE, Van Why SK, Ganz MB, Kashgarian M, Siegel NJ, Stewart AF.

J Clin Invest. 1993 Dec;92(6):2850-7.

33.

ddAVP does not stimulate acute changes in levels of medullary trimethylamines in humans.

Avison MJ, Van Why SK, Siegel NJ.

J Am Soc Nephrol. 1993 Dec;4(6):1379-84.

34.

Alterations in mitochondrial RNA expression after renal ischemia.

Van Itallie CM, Van Why S, Thulin G, Kashgarian M, Siegel NJ.

Am J Physiol. 1993 Sep;265(3 Pt 1):C712-9.

PMID:
7692737
35.

Abdominal symptoms as presentation of hypertensive crisis.

Van Why SK, Boydstun II, Gaudio KM, Siegel NJ.

Am J Dis Child. 1993 Jun;147(6):638-41.

PMID:
8506831
36.

Disassociation of postischemic recovery of renal adenosine triphosphate and cellular integrity.

Boydstun II, Thulin G, Zhu XH, Avison MJ, Gaudio KM, Siegel NJ.

Pediatr Res. 1993 Jun;33(6):595-7.

PMID:
8378118
37.

Induction and intracellular localization of HSP-72 after renal ischemia.

Van Why SK, Hildebrandt F, Ardito T, Mann AS, Siegel NJ, Kashgarian M.

Am J Physiol. 1992 Nov;263(5 Pt 2):F769-75.

PMID:
1443167
38.

Role of nucleoside uptake in renal postischemic ATP synthesis.

Van Waarde A, Avison MJ, Thulin G, Gaudio KM, Shulman RG, Siegel NJ.

Am J Physiol. 1992 Jun;262(6 Pt 2):F1092-9.

PMID:
1621813
39.

Redistribution of cellular energy following renal ischemia.

Gaudio KM, Thulin G, Ardito T, Kashgarian M, Siegel NJ.

Pediatr Nephrol. 1991 Sep;5(5):591-6.

PMID:
1911145
40.

1H NMR study of renal trimethylamine responses to dehydration and acute volume loading in man.

Avison MJ, Rothman DL, Nixon TW, Long WS, Siegel NJ.

Proc Natl Acad Sci U S A. 1991 Jul 15;88(14):6053-7.

41.

A novel approach to training pediatrics primary care residents.

Baldwin SE, McCarthy PL, Forsyth BW, Leventhal JM, Granger RH, Faraclas WG, Anyan W, Siegel NJ.

Acad Med. 1991 Apr;66(4):239-41.

PMID:
2012659
42.

The drug abusing adolescent: clinical issues.

Ungerleider JT, Siegel NJ.

Psychiatr Clin North Am. 1990 Sep;13(3):435-42.

PMID:
2235692
43.

Management of acute renal failure in children.

Siegel NJ.

Pediatr Nephrol. 1990 Jul;4(4):358. No abstract available.

PMID:
2206904
44.

Idiopathic Fanconi syndrome with progressive renal failure: a case report and discussion.

Long WS, Seashore MR, Siegel NJ, Bia MJ.

Yale J Biol Med. 1990 Jan-Feb;63(1):15-28.

45.

Metabolic alterations in proximal tubule suspensions obtained from ischemic kidneys.

Gaudio KM, Thulin G, Ardito T, Kashgarian M, Siegel NJ.

Am J Physiol. 1989 Sep;257(3 Pt 2):F383-9.

PMID:
2551186
46.

Position paper on current status and future needs of pediatric nephrology in the United States: training and research. Writing Committee of the American Society of Pediatric Nephrology.

Chesney RW, Arant BS Jr, Hirschmann G, Jose PA, Novello AC, Siegel NJ.

Pediatr Nephrol. 1989 Jul;3(3):372-80. No abstract available.

PMID:
2702120
47.

Metabolic alterations in the kidney during ischemic acute renal failure.

Avison MJ, van Waarde A, Stromski ME, Gaudio K, Siegel NJ.

Semin Nephrol. 1989 Mar;9(1):98-101. No abstract available.

PMID:
2740655
48.

Protection of the kidney against ischemic injury by inhibition of 5'-nucleotidase.

Van Waarde A, Stromski ME, Thulin G, Gaudio KM, Kashgarian M, Shulman RG, Siegel NJ.

Am J Physiol. 1989 Feb;256(2 Pt 2):F298-305.

PMID:
2537026
49.

Transient renal dysfunction of the neonate.

Hijazi Z, Keller MS, Gaudio KM, Siegel NJ.

Pediatrics. 1988 Dec;82(6):929-30. No abstract available.

PMID:
3054789
50.

Metabolic and functional consequences of inhibiting adenosine deaminase during renal ischemia in rats.

Stromski ME, van Waarde A, Avison MJ, Thulin G, Gaudio KM, Kashgarian M, Shulman RG, Siegel NJ.

J Clin Invest. 1988 Nov;82(5):1694-9.

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