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Items: 48

1.

Decanalizing thinking on genetic canalization.

Geiler-Samerotte K, Sartori FMO, Siegal ML.

Semin Cell Dev Biol. 2018 May 24. pii: S1084-9521(17)30295-1. doi: 10.1016/j.semcdb.2018.05.008. [Epub ahead of print] Review.

PMID:
29751086
2.

Correction: A sibling method for identifying vQTLs.

Conley D, Johnson R, Domingue B, Dawes C, Boardman J, Siegal ML.

PLoS One. 2018 May 1;13(5):e0196881. doi: 10.1371/journal.pone.0196881. eCollection 2018.

3.

A sibling method for identifying vQTLs.

Conley D, Johnson R, Domingue B, Dawes C, Boardman J, Siegal ML.

PLoS One. 2018 Apr 4;13(4):e0194541. doi: 10.1371/journal.pone.0194541. eCollection 2018. Erratum in: PLoS One. 2018 May 1;13(5):e0196881.

4.

Deep sequencing of natural and experimental populations of Drosophila melanogaster reveals biases in the spectrum of new mutations.

Assaf ZJ, Tilk S, Park J, Siegal ML, Petrov DA.

Genome Res. 2017 Dec;27(12):1988-2000. doi: 10.1101/gr.219956.116. Epub 2017 Oct 27.

5.

Resolving the Complex Genetic Basis of Phenotypic Variation and Variability of Cellular Growth.

Ziv N, Shuster BM, Siegal ML, Gresham D.

Genetics. 2017 Jul;206(3):1645-1657. doi: 10.1534/genetics.116.195180. Epub 2017 May 11.

6.

Molecular genetics: Chaperone protein gets personal.

Siegal ML.

Nature. 2017 May 4;545(7652):36-37. doi: 10.1038/nature22487. Epub 2017 Apr 19. No abstract available.

PMID:
28424517
7.

Selection Transforms the Landscape of Genetic Variation Interacting with Hsp90.

Geiler-Samerotte KA, Zhu YO, Goulet BE, Hall DW, Siegal ML.

PLoS Biol. 2016 Oct 21;14(10):e2000465. doi: 10.1371/journal.pbio.2000465. eCollection 2016 Oct.

8.

Sibling genes as environment: Sibling dopamine genotypes and adolescent health support frequency dependent selection.

Rauscher E, Conley D, Siegal ML.

Soc Sci Res. 2015 Nov;54:209-20. doi: 10.1016/j.ssresearch.2015.08.002. Epub 2015 Aug 18.

PMID:
26463544
9.

Engineering and Biology: Counsel for a Continued Relationship.

Calcott B, Levy A, Siegal ML, Soyer OS, Wagner A.

Biol Theory. 2015 Mar;10(1):50-59.

10.

A Philosophical Perspective on Evolutionary Systems Biology.

O'Malley MA, Soyer OS, Siegal ML.

Biol Theory. 2015 Mar 1;10:6-17.

11.

On the Nature and Evolutionary Impact of Phenotypic Robustness Mechanisms.

Siegal ML, Leu JY.

Annu Rev Ecol Evol Syst. 2014 Nov 1;45:496-517.

12.

Shifting sugars and shifting paradigms.

Siegal ML.

PLoS Biol. 2015 Feb 17;13(2):e1002068. doi: 10.1371/journal.pbio.1002068. eCollection 2015 Feb.

13.

Essential gene disruptions reveal complex relationships between phenotypic robustness, pleiotropy, and fitness.

Bauer CR, Li S, Siegal ML.

Mol Syst Biol. 2015 Jan 21;11(1):773. doi: 10.15252/msb.20145264.

14.

Reply to Chen and Zhang: On interpreting genome-wide trends from yeast mutation accumulation data.

Zhu YO, Siegal ML, Hall DW, Petrov DA.

Proc Natl Acad Sci U S A. 2014 Sep 30;111(39):E4063. doi: 10.1073/pnas.1413861111. Epub 2014 Sep 12. No abstract available.

15.

The genetics of sex: exploring differences.

Arbeitman MN, Kopp A, Siegal ML, Van Doren M.

G3 (Bethesda). 2014 Jun 17;4(6):979-81. doi: 10.1534/g3.114.011692.

16.

Precise estimates of mutation rate and spectrum in yeast.

Zhu YO, Siegal ML, Hall DW, Petrov DA.

Proc Natl Acad Sci U S A. 2014 Jun 3;111(22):E2310-8. doi: 10.1073/pnas.1323011111. Epub 2014 May 20.

17.

Testing the key assumption of heritability estimates based on genome-wide genetic relatedness.

Conley D, Siegal ML, Domingue BW, Mullan Harris K, McQueen MB, Boardman JD.

J Hum Genet. 2014 Jun;59(6):342-5. doi: 10.1038/jhg.2014.14. Epub 2014 Mar 6.

18.

Histone variant HTZ1 shows extensive epistasis with, but does not increase robustness to, new mutations.

Richardson JB, Uppendahl LD, Traficante MK, Levy SF, Siegal ML.

PLoS Genet. 2013;9(8):e1003733. doi: 10.1371/journal.pgen.1003733. Epub 2013 Aug 22.

19.

Genetic and nongenetic determinants of cell growth variation assessed by high-throughput microscopy.

Ziv N, Siegal ML, Gresham D.

Mol Biol Evol. 2013 Dec;30(12):2568-78. doi: 10.1093/molbev/mst138. Epub 2013 Aug 11.

20.

Heritability and the equal environments assumption: evidence from multiple samples of misclassified twins.

Conley D, Rauscher E, Dawes C, Magnusson PK, Siegal ML.

Behav Genet. 2013 Sep;43(5):415-26. doi: 10.1007/s10519-013-9602-1. Epub 2013 Aug 1.

PMID:
23903437
21.

Beyond orchids and dandelions: testing the 5-HTT "risky" allele for evidence of phenotypic capacitance and frequency-dependent selection.

Conley D, Rauscher E, Siegal ML.

Biodemography Soc Biol. 2013;59(1):37-56. doi: 10.1080/19485565.2013.774620.

22.

The details in the distributions: why and how to study phenotypic variability.

Geiler-Samerotte KA, Bauer CR, Li S, Ziv N, Gresham D, Siegal ML.

Curr Opin Biotechnol. 2013 Aug;24(4):752-9. doi: 10.1016/j.copbio.2013.03.010. Epub 2013 Apr 6.

23.

Crouching variation revealed.

Siegal ML.

Mol Ecol. 2013 Mar;22(5):1187-9. doi: 10.1111/mec.12195.

PMID:
23437837
24.

Oh, the places they'll go: Female sperm storage and sperm precedence in Drosophila melanogaster.

Schnakenberg SL, Siegal ML, Bloch Qazi MC.

Spermatogenesis. 2012 Jul 1;2(3):224-235.

25.

The robustness continuum.

Levy SF, Siegal ML.

Adv Exp Med Biol. 2012;751:431-52. doi: 10.1007/978-1-4614-3567-9_20.

PMID:
22821470
26.

Polygenic cis-regulatory adaptation in the evolution of yeast pathogenicity.

Fraser HB, Levy S, Chavan A, Shah HB, Perez JC, Zhou Y, Siegal ML, Sinha H.

Genome Res. 2012 Oct;22(10):1930-9. doi: 10.1101/gr.134080.111. Epub 2012 May 29.

27.

Pausing on the path to robustness.

Siegal ML, Rushlow C.

Dev Cell. 2012 May 15;22(5):905-6. doi: 10.1016/j.devcel.2012.04.020.

28.

Bet hedging in yeast by heterogeneous, age-correlated expression of a stress protectant.

Levy SF, Ziv N, Siegal ML.

PLoS Biol. 2012;10(5):e1001325. doi: 10.1371/journal.pbio.1001325. Epub 2012 May 8.

29.

Hsp90 depletion goes wild.

Siegal ML, Masel J.

BMC Biol. 2012 Feb 27;10:14. doi: 10.1186/1741-7007-10-14.

30.

Sperm-storage defects and live birth in Drosophila females lacking spermathecal secretory cells.

Schnakenberg SL, Matias WR, Siegal ML.

PLoS Biol. 2011 Nov;9(11):e1001192. doi: 10.1371/journal.pbio.1001192. Epub 2011 Nov 8.

31.

The female-specific doublesex isoform regulates pleiotropic transcription factors to pattern genital development in Drosophila.

Chatterjee SS, Uppendahl LD, Chowdhury MA, Ip PL, Siegal ML.

Development. 2011 Mar;138(6):1099-109. doi: 10.1242/dev.055731.

32.

Everything you always wanted to know about sex ... in flies.

Arbeitman MN, Kopp A, Siegal ML, Van Doren M.

Sex Dev. 2010;4(6):315-20. doi: 10.1159/000320632. Epub 2010 Oct 8.

33.

Correlating gene expression variation with cis-regulatory polymorphism in Saccharomyces cerevisiae.

Chen K, van Nimwegen E, Rajewsky N, Siegal ML.

Genome Biol Evol. 2010;2:697-707. doi: 10.1093/gbe/evq054. Epub 2010 Sep 9.

34.

Robustness: mechanisms and consequences.

Masel J, Siegal ML.

Trends Genet. 2009 Sep;25(9):395-403. doi: 10.1016/j.tig.2009.07.005. Epub 2009 Aug 28. Review.

35.

Reexamining microRNA site accessibility in Drosophila: a population genomics study.

Chen K, Maaskola J, Siegal ML, Rajewsky N.

PLoS One. 2009 May 25;4(5):e5681. doi: 10.1371/journal.pone.0005681.

36.

Network hubs buffer environmental variation in Saccharomyces cerevisiae.

Levy SF, Siegal ML.

PLoS Biol. 2008 Nov 4;6(11):e264. doi: 10.1371/journal.pbio.0060264.

37.

Functional and evolutionary inference in gene networks: does topology matter?

Siegal ML, Promislow DE, Bergman A.

Genetica. 2007 Jan;129(1):83-103. Epub 2006 Aug 8.

PMID:
16897451
38.
39.

A genomic analysis of Drosophila somatic sexual differentiation and its regulation.

Arbeitman MN, Fleming AA, Siegal ML, Null BH, Baker BS.

Development. 2004 May;131(9):2007-21. Epub 2004 Mar 31.

40.

Evolutionary capacitance as a general feature of complex gene networks.

Bergman A, Siegal ML.

Nature. 2003 Jul 31;424(6948):549-52.

PMID:
12891357
41.
42.

Waddington's canalization revisited: developmental stability and evolution.

Siegal ML, Bergman A.

Proc Natl Acad Sci U S A. 2002 Aug 6;99(16):10528-32. Epub 2002 Jun 24.

43.

The evolution of dosage-compensation mechanisms.

MarĂ­n I, Siegal ML, Baker BS.

Bioessays. 2000 Dec;22(12):1106-14. Review.

PMID:
11084626
44.

Application of Cre/loxP in Drosophila. Site-specific recombination and transgene coplacement.

Siegal ML, Hartl DL.

Methods Mol Biol. 2000;136:487-95. Review. No abstract available.

PMID:
10840736
45.
46.
47.

Triple-ligation strategy with advantages over directional cloning.

Siegal ML, Petrov DA, De Aguiar D.

Biotechniques. 1996 Oct;21(4):614, 616, 618-9. No abstract available.

PMID:
8891209

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