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Items: 49

1.

Building Machine-Learning Scoring Functions for Structure-Based Prediction of Intermolecular Binding Affinity.

Wójcikowski M, Siedlecki P, Ballester PJ.

Methods Mol Biol. 2019;2053:1-12. doi: 10.1007/978-1-4939-9752-7_1.

PMID:
31452095
2.

Targeting peroxiredoxin 1 impairs growth of breast cancer cells and potently sensitises these cells to prooxidant agents.

Bajor M, Zych AO, Graczyk-Jarzynka A, Muchowicz A, Firczuk M, Trzeciak L, Gaj P, Domagala A, Siernicka M, Zagozdzon A, Siedlecki P, Kniotek M, O'Leary PC, Golab J, Zagozdzon R.

Br J Cancer. 2018 Oct;119(7):873-884. doi: 10.1038/s41416-018-0263-y. Epub 2018 Oct 5.

3.

Development of a protein-ligand extended connectivity (PLEC) fingerprint and its application for binding affinity predictions.

Wójcikowski M, Kukiełka M, Stepniewska-Dziubinska MM, Siedlecki P.

Bioinformatics. 2019 Apr 15;35(8):1334-1341. doi: 10.1093/bioinformatics/bty757.

4.

End-tidal carbon dioxide levels in patients with post-concussion syndrome during neurocognitive and physical tasks compared to a normative control group.

Siedlecki P, Sanzo P, Zerpa C, Newhouse I.

Brain Inj. 2018;32(13-14):1824-1833. doi: 10.1080/02699052.2018.1506945. Epub 2018 Aug 1.

PMID:
30067397
5.

Development and evaluation of a deep learning model for protein-ligand binding affinity prediction.

Stepniewska-Dziubinska MM, Zielenkiewicz P, Siedlecki P.

Bioinformatics. 2018 Nov 1;34(21):3666-3674. doi: 10.1093/bioinformatics/bty374.

6.

Arrhythmic manifestation of peripartum cardiomyopathy-Case report.

Siedlecki P, Kurpesa M, Uznańska-Loch B, Trzos E, Kasprzak JD.

Ann Noninvasive Electrocardiol. 2019 Jan;24(1):e12551. doi: 10.1111/anec.12551. Epub 2018 Apr 17.

PMID:
29667277
7.

[Prevention of cardiovascular diseases - Prophylactic program in a selected enterprise].

Siedlecka J, Gadzicka E, Szyjkowska A, Siedlecki P, Szymczak W, Makowiec-Dąbrowska T, Bortkiewicz A.

Med Pr. 2017 Oct 17;68(6):757-769. doi: 10.13075/mp.5893.00548. Epub 2017 Sep 18. Polish.

8.

DeCAF-Discrimination, Comparison, Alignment Tool for 2D PHarmacophores.

Stepniewska-Dziubinska MM, Zielenkiewicz P, Siedlecki P.

Molecules. 2017 Jul 6;22(7). pii: E1128. doi: 10.3390/molecules22071128.

9.

Performance of machine-learning scoring functions in structure-based virtual screening.

Wójcikowski M, Ballester PJ, Siedlecki P.

Sci Rep. 2017 Apr 25;7:46710. doi: 10.1038/srep46710.

10.

Characterization of mAb6-9-1 monoclonal antibody against hemagglutinin of avian influenza virus H5N1 and its engineered derivative, single-chain variable fragment antibody.

Sawicka R, Siedlecki P, Kalenik B, Radomski JP, Sączyńska V, Porębska A, Szewczyk B, Sirko A, Góra-Sochacka A.

Acta Biochim Pol. 2017;64(1):85-92. doi: 10.18388/abp.2016_1292. Epub 2016 Dec 7.

11.

A Specialized Histone H1 Variant Is Required for Adaptive Responses to Complex Abiotic Stress and Related DNA Methylation in Arabidopsis.

Rutowicz K, Puzio M, Halibart-Puzio J, Lirski M, Kotliński M, Kroteń MA, Knizewski L, Lange B, Muszewska A, Śniegowska-Świerk K, Kościelniak J, Iwanicka-Nowicka R, Buza K, Janowiak F, Żmuda K, Jõesaar I, Laskowska-Kaszub K, Fogtman A, Kollist H, Zielenkiewicz P, Tiuryn J, Siedlecki P, Swiezewski S, Ginalski K, Koblowska M, Archacki R, Wilczynski B, Rapacz M, Jerzmanowski A.

Plant Physiol. 2015 Nov;169(3):2080-101. doi: 10.1104/pp.15.00493. Epub 2015 Sep 8.

12.

Impedance cardiography - Old method, new opportunities. Part II. Testing of cardiovascular response to various factors of work environment.

Siedlecka J, Siedlecki P, Bortkiewicz A.

Int J Occup Med Environ Health. 2015;28(1):34-41. doi: 10.13075/ijomeh.1896.00450. Review.

13.

Impedance cardiography - Old method, new opportunities. Part I. Clinical applications.

Siedlecka J, Siedlecki P, Bortkiewicz A.

Int J Occup Med Environ Health. 2015;28(1):27-33. doi: 10.13075/ijomeh.1896.00451. Review.

14.

Open Drug Discovery Toolkit (ODDT): a new open-source player in the drug discovery field.

Wójcikowski M, Zielenkiewicz P, Siedlecki P.

J Cheminform. 2015 Jun 22;7:26. doi: 10.1186/s13321-015-0078-2. eCollection 2015.

15.

Genetic diversity of SCN5A gene and its possible association with the concealed form of Brugada syndrome development in Polish group of patients.

Uziębło-Życzkowska B, Gielerak G, Siedlecki P, Pająk B.

Biomed Res Int. 2014;2014:462609. doi: 10.1155/2014/462609. Epub 2014 Oct 20.

16.

Short communication: Antimicrobial susceptibility profiling and genotyping of Staphylococcus aureus isolates from bovine mastitis in Poland.

Jagielski T, Puacz E, Lisowski A, Siedlecki P, Dudziak W, Międzobrodzki J, Krukowski H.

J Dairy Sci. 2014 Oct;97(10):6122-8. doi: 10.3168/jds.2014-8321. Epub 2014 Jul 30.

17.

Genetic diversity of hemagglutinin gene of A(H1N1)pdm09 influenza strains isolated in Taiwan and its potential impact on HA-neutralizing epitope interaction.

Łepek K, Pająk B, Siedlecki P, Niemcewicz M, Kocik J, Wu HS, Yang JR, Kucharczyk K, Szewczyk B.

Hum Vaccin Immunother. 2014;10(3):577-85. Epub 2014 Jan 9.

18.

DiSCuS: an open platform for (not only) virtual screening results management.

Wójcikowski M, Zielenkiewicz P, Siedlecki P.

J Chem Inf Model. 2014 Jan 27;54(1):347-54. doi: 10.1021/ci400587f. Epub 2014 Jan 3.

PMID:
24364790
19.

Rhythmic diel pattern of gene expression in juvenile maize leaf.

Jończyk M, Sobkowiak A, Siedlecki P, Biecek P, Trzcinska-Danielewicz J, Tiuryn J, Fronk J, Sowiński P.

PLoS One. 2011;6(8):e23628. doi: 10.1371/journal.pone.0023628. Epub 2011 Aug 17.

20.

Sequence diversity and potential recombination events in the coat protein gene of Apple stem pitting virus.

Komorowska B, Siedlecki P, Kaczanowski S, Hasiów-Jaroszewska B, Malinowski T.

Virus Res. 2011 Jun;158(1-2):263-7. doi: 10.1016/j.virusres.2011.03.003. Epub 2011 Mar 23.

PMID:
21402110
21.

The High Throughput Sequence Annotation Service (HT-SAS) - the shortcut from sequence to true Medline words.

Kaczanowski S, Siedlecki P, Zielenkiewicz P.

BMC Bioinformatics. 2009 May 16;10:148. doi: 10.1186/1471-2105-10-148.

22.

e-LiSe--an online tool for finding needles in the '(Medline) haystack'.

Gladki A, Siedlecki P, Kaczanowski S, Zielenkiewicz P.

Bioinformatics. 2008 Apr 15;24(8):1115-7. doi: 10.1093/bioinformatics/btn086. Epub 2008 Mar 5.

PMID:
18321884
23.

Nicotiana tabacum osmotic stress-activated kinase is regulated by phosphorylation on Ser-154 and Ser-158 in the kinase activation loop.

Burza AM, Pekala I, Sikora J, Siedlecki P, Małagocki P, Bucholc M, Koper L, Zielenkiewicz P, Dadlez M, Dobrowolska G.

J Biol Chem. 2006 Nov 10;281(45):34299-311. Epub 2006 Sep 15.

24.

Novel thienopyrrole glycogen phosphorylase inhibitors: synthesis, in vitro SAR and crystallographic studies.

Whittamore PR, Addie MS, Bennett SN, Birch AM, Butters M, Godfrey L, Kenny PW, Morley AD, Murray PM, Oikonomakos NG, Otterbein LR, Pannifer AD, Parker JS, Readman K, Siedlecki PS, Schofield P, Stocker A, Taylor MJ, Townsend LA, Whalley DP, Whitehouse J.

Bioorg Med Chem Lett. 2006 Nov 1;16(21):5567-71. Epub 2006 Aug 30.

PMID:
16945526
25.

Mammalian DNA methyltransferases.

Siedlecki P, Zielenkiewicz P.

Acta Biochim Pol. 2006;53(2):245-56. Epub 2006 Apr 3. Review.

26.

Synthesis and in vitro evaluation of biotinylated RG108: a high affinity compound for studying binding interactions with human DNA methyltransferases.

Schirrmacher E, Beck C, Brueckner B, Schmitges F, Siedlecki P, Bartenstein P, Lyko F, Schirrmacher R.

Bioconjug Chem. 2006 Mar-Apr;17(2):261-6.

PMID:
16536454
27.

Discovery of two novel, small-molecule inhibitors of DNA methylation.

Siedlecki P, Garcia Boy R, Musch T, Brueckner B, Suhai S, Lyko F, Zielenkiewicz P.

J Med Chem. 2006 Jan 26;49(2):678-83.

PMID:
16420053
28.

Epigenetic reactivation of tumor suppressor genes by a novel small-molecule inhibitor of human DNA methyltransferases.

Brueckner B, Garcia Boy R, Siedlecki P, Musch T, Kliem HC, Zielenkiewicz P, Suhai S, Wiessler M, Lyko F.

Cancer Res. 2005 Jul 15;65(14):6305-11.

29.

Establishment and functional validation of a structural homology model for human DNA methyltransferase 1.

Siedlecki P, Garcia Boy R, Comagic S, Schirrmacher R, Wiessler M, Zielenkiewicz P, Suhai S, Lyko F.

Biochem Biophys Res Commun. 2003 Jun 27;306(2):558-63.

PMID:
12804601
30.

A phase II study of intravenous navelbine and doxorubicin combination in previously untreated advanced breast carcinoma.

Pawlicki M, Rolski J, Zaluski J, Siedlecki P, Ramlau C, Tomzak P.

Oncologist. 2002;7(3):205-9.

31.

Prospective randomized trial of docetaxel versus mitomycin plus vinblastine in patients with metastatic breast cancer progressing despite previous anthracycline-containing chemotherapy. 304 Study Group.

Nabholtz JM, Senn HJ, Bezwoda WR, Melnychuk D, Deschênes L, Douma J, Vandenberg TA, Rapoport B, Rosso R, Trillet-Lenoir V, Drbal J, Molino A, Nortier JW, Richel DJ, Nagykalnai T, Siedlecki P, Wilking N, Genot JY, Hupperets PS, Pannuti F, Skarlos D, Tomiak EM, Murawsky M, Alakl M, Aapro M, et al.

J Clin Oncol. 1999 May;17(5):1413-24.

PMID:
10334526
32.

Tolerability and efficacy of GM-CSF [Leucomax] in patients with small cell lung cancer treated with intensive chemotherapy.

Walewski J, Romejko-Jarosińska J, Zwoliński J, Falkowski S, Siedlecki P.

Med Oncol. 1996 Dec;13(4):199-205.

PMID:
9152970
33.
34.
35.

[Early results of hormonal treatment of advanced breast cancer with aminoglutethimide].

Pieńkowski T, Zborzil J, Siedlecki P, Flis E, Pałucka A, Pieńkowska F, Rubách M, Piotrowski J.

Pol Tyg Lek. 1988 Aug 15;43(33):1057-9. Polish. No abstract available.

PMID:
3072540
36.

[Health protection for working medical personnel while administering cytostatics].

Nowacki MP, Siedlecki P.

Pieleg Polozna. 1988;(4):8. Polish. No abstract available.

PMID:
3399552
37.
38.

[Preliminary evaluation of the effectiveness of a modified treatment program in patients with malignant testicular neoplasms].

Madej G, Siedlecki P, Meyza J.

Pol Tyg Lek. 1987 Jul 6-7;42(27-28):836-40. Polish. No abstract available.

PMID:
2446291
39.

[Should the truth be disclosed to cancer patients?].

Siedlecki P.

Nowotwory. 1987 Jul-Sep;37(3):185-8. Polish. No abstract available.

PMID:
3438171
40.

[Toxicity of cytostatics for hospital personnel].

Siedlecki P.

Nowotwory. 1987 Jan-Mar;37(1):56-9. Polish. No abstract available.

PMID:
3628031
41.

[Preliminary evaluation of the toxicity and effectiveness of chemotherapy using the VAB-6 protocol in the treatment of non-seminoma of the testis].

Madej G, Gigier A, Siedlecki P, Pieńkowski T.

Nowotwory. 1987 Jan-Mar;37(1):44-9. Polish. No abstract available.

PMID:
2442730
42.

[Preliminary results of the treatment with aminoglutethimide of patients with advanced breast cancer].

Pieńkowski T, Zborzil J, Pieńkowska F, Siedlecki P, Rubach M.

Nowotwory. 1985 Jul-Sep;35(3):249-54. Polish. No abstract available.

PMID:
4088900
43.

[Evaluation of the results of treatment with medroxyprogesterone acetate (MPA) of patients with advanced breast cancer].

Pieńkowska F, Siedlecki P, Pieńkowski T, Zborzil J, Rubach M.

Nowotwory. 1985 Jul-Sep;35(3):243-8. Polish. No abstract available.

PMID:
2935789
44.

[Evaluation of tamoxifen in the treatment of female patients with advanced breast cancer].

Pieńkowska F, Pieńkowski T, Siedlecki P, Zborzil J, Paszko Z, Padzik H, Rubach M.

Nowotwory. 1985 Apr-Jun;35(2):137-44. Polish. No abstract available.

PMID:
3911172
46.

[Clinical evaluation of ifosfamide in one-agent chemotherapy of malignant testicular tumors].

Madej G, Porwit-Ksiazek A, Siedlecki P, Zborzil J.

Pol Tyg Lek. 1982 Jul 26;37(24-25):717-9. Polish. No abstract available.

PMID:
6294642
47.

[Preliminary evaluation of cisplatin in the treatment of malignant testicular neoplasms other than seminomas].

Madej G, Zborzil J, Siedlecki P, Porwit-Ksiazek A.

Pol Tyg Lek. 1981 Jun 29;36(26):967-70. Polish. No abstract available.

PMID:
6270638
48.

[Results of chemotherapy with bleomycin and vinblastine of malignant testicular neoplasms at the Warsaw Institute of Oncology in the years 1977-1978].

Madej G, Zborzil J, Siedlecki P.

Pol Tyg Lek. 1979 Nov 19;34(47):1821-4. Polish. No abstract available.

PMID:
93276
49.

[Results of chemotherapy in Ewing's sarcoma].

Siedlecki P, Zulawski M.

Nowotwory. 1976;Suppl:111-3. Polish. No abstract available.

PMID:
1019043

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