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Discontinuation, persistence and adherence to subcutaneous biologics delivered via a homecare route to Scottish adults with rheumatic diseases: a retrospective study.

Alvarez-Madrazo S, Kavanagh K, Siebert S, Semple Y, Godman B, Maciel Almeida A, Acurcio FA, Bennie M.

BMJ Open. 2019 Sep 4;9(9):e027059. doi: 10.1136/bmjopen-2018-027059.


Stem cell differentiation trajectories in Hydra resolved at single-cell resolution.

Siebert S, Farrell JA, Cazet JF, Abeykoon Y, Primack AS, Schnitzler CE, Juliano CE.

Science. 2019 Jul 26;365(6451). pii: eaav9314. doi: 10.1126/science.aav9314.


Cardiometabolic comorbidities in RA and PsA: lessons learned and future directions.

Ferguson LD, Siebert S, McInnes IB, Sattar N.

Nat Rev Rheumatol. 2019 Aug;15(8):461-474. doi: 10.1038/s41584-019-0256-0. Epub 2019 Jul 10. Review.


Molecular Mechanisms Driving Switch Behavior in Xylem Cell Differentiation.

Turco GM, Rodriguez-Medina J, Siebert S, Han D, Valderrama-Gómez MÁ, Vahldick H, Shulse CN, Cole BJ, Juliano CE, Dickel DE, Savageau MA, Brady SM.

Cell Rep. 2019 Jul 9;28(2):342-351.e4. doi: 10.1016/j.celrep.2019.06.041.


Model-based evaluation of the long-term cost-effectiveness of systematic case-finding for COPD in primary care.

Lambe T, Adab P, Jordan RE, Sitch A, Enocson A, Jolly K, Marsh J, Riley R, Miller M, Cooper BG, Turner AM, Ayres JG, Stockley R, Greenfield S, Siebert S, Daley A, Cheng KK, Fitzmaurice D, Jowett S.

Thorax. 2019 Aug;74(8):730-739. doi: 10.1136/thoraxjnl-2018-212148. Epub 2019 Jul 8.


Scientific Business Abstracts of the 112th Annual Meeting of the Association of Physicians of Great Britain and Ireland.

Chauhan A, Lalor T, Watson S, Adams D, Farrah TE, Anand A, Kimmitt R, Mills NL, Webb DJ, Dhaun N, Kalla R, Adams A, Vatn S, Bonfliglio F, Nimmo E, Kennedy N, Ventham N, Vatn M, Ricanek P, Halfvarson J, Soderhollm J, Pierik M, Torkvist L, Gomollon F, Gut I, Jahnsen J, Satsangi J, Body R, Almashali M, McDowell G, Taylor P, Lacey A, Rees A, Dayan C, Lazarus J, Nelson S, Okosieme O, Corcoran D, Young R, Ciadella P, McCartney P, Bajrangee A, Hennigan B, Collison D, Carrick D, Shaukat A, Good R, Watkins S, McEntegart M, Watt J, Welsh P, Sattar N, McConnachie A, Oldroyd K, Berry C, Parks T, Auckland K, Mentzer AJ, Kado J, Mirabel MM, Kauwe JK, Robson KJ, Mittal B, Steer AC, Hill AVS, Akbar M, Forrester M, Virlan AT, Gilmour A, Wallace C, Paterson C, Reid D, Siebert S, Porter D, Liversidge J, McInnes I, Goodyear C, Athwal V, Pritchett J, Zaitoun A, Irving W, Guha IN, Hanley NA, Hanley KP, Briggs T, Reynolds J, Rice G, Bondet V, Bruce E, Crow Y, Duffy D, Parker B, Bruce I, Martin K, Pritchett J, Aoibheann Mullan M, Llewellyn J, Athwal V, Zeef L, Farrow S, Streuli C, Henderson N, Friedman S, Hanley N, Hanley KP.

QJM. 2018 Dec 1;111(12):920-924. doi: 10.1093/qjmed/hcy193. No abstract available.


Comorbidity burden in axial spondyloarthritis: a cluster analysis.

Zhao SS, Radner H, Siebert S, Duffield SJ, Thong D, Hughes DM, Moots RJ, Solomon DH, Goodson NJ.

Rheumatology (Oxford). 2019 Apr 9. pii: kez119. doi: 10.1093/rheumatology/kez119. [Epub ahead of print]


The associations between self-reported depression, self-reported chronic inflammatory conditions and cognitive abilities in UK Biobank.

Lyall LM, Cullen B, Lyall DM, Leighton SP, Siebert S, Smith DJ, Cavanagh J.

Eur Psychiatry. 2019 Aug;60:63-70. doi: 10.1016/j.eurpsy.2019.05.007. Epub 2019 May 31.


AxSpA patients who also meet criteria for fibromyalgia: identifying distinct patient clusters using data from a UK national register (BSRBR-AS).

Macfarlane GJ, Pathan E, Siebert S, Packham J, Gaffney K, Choy E, Sengupta R, Atzeni F, Martin KR, Jones GT, Dean LE.

BMC Rheumatol. 2019 May 20;3:19. doi: 10.1186/s41927-019-0066-7. eCollection 2019.


Association of central adiposity with psoriasis, psoriatic arthritis and rheumatoid arthritis: a cross-sectional study of the UK Biobank.

Ferguson LD, Brown R, Celis-Morales C, Welsh P, Lyall DM, Pell JP, McInnes IB, Siebert S, Sattar N.

Rheumatology (Oxford). 2019 May 25. pii: kez192. doi: 10.1093/rheumatology/kez192. [Epub ahead of print]


Responsiveness of Serum C-Reactive Protein, Interleukin-17A, and Interleukin-17F Levels to Ustekinumab in Psoriatic Arthritis: Lessons From Two Phase III, Multicenter, Double-Blind, Placebo-Controlled Trials.

Siebert S, Sweet K, Dasgupta B, Campbell K, McInnes IB, Loza MJ.

Arthritis Rheumatol. 2019 May 9. doi: 10.1002/art.40921. [Epub ahead of print]


Loss of Msh2 and a single-radiation hit induce common, genome-wide, and persistent epigenetic changes in the intestine.

Herberg M, Siebert S, Quaas M, Thalheim T, Rother K, Hussong M, Altmüller J, Kerner C, Galle J, Schweiger MR, Aust G.

Clin Epigenetics. 2019 Apr 27;11(1):65. doi: 10.1186/s13148-019-0639-8.


Alopecia areata is characterized by dysregulation in systemic type 17 and type 2 cytokines, which may contribute to disease-associated psychological morbidity.

Bain KA, McDonald E, Moffat F, Tutino M, Castelino M, Barton A, Cavanagh J, Ijaz UZ, Siebert S, McInnes IB, Astrand A, Holmes S, Milling SWF.

Br J Dermatol. 2019 Apr 13. doi: 10.1111/bjd.18008. [Epub ahead of print]


Association of Diverticulitis with Prolonged Spondyloarthritis: An Analysis of the ASAS-COMOSPA International Cohort.

Derakhshan MH, Goodson NJ, Packham J, Sengupta R, Molto A, Marzo-Ortega H, Siebert S; BRITSpA and the ASAS-COMOSPA Investigators.

J Clin Med. 2019 Feb 26;8(3). pii: E281. doi: 10.3390/jcm8030281.


JAK-inhibitors. New players in the field of immune-mediated diseases, beyond rheumatoid arthritis.

Fragoulis GE, McInnes IB, Siebert S.

Rheumatology (Oxford). 2019 Feb 1;58(Supplement_1):i43-i54. doi: 10.1093/rheumatology/key276.


Non-Radiographic Axial Spondyloarthritis (nr-axSpA): Advances in Classification, Imaging and Therapy.

Robinson PC, Sengupta R, Siebert S.

Rheumatol Ther. 2019 Jun;6(2):165-177. doi: 10.1007/s40744-019-0146-6. Epub 2019 Feb 20. Review.


Europe rules on harm from fluoroquinolone antibiotics.

Millar NL, Siebert S, McInnes IB.

Nature. 2019 Feb;566(7744):326. doi: 10.1038/d41586-019-00619-7. No abstract available.


Protocol for a multicentre randomised controlled parallel-group trial to compare the effectiveness of remotely delivered cognitive-behavioural and graded exercise interventions with usual care alone to lessen the impact of fatigue in inflammatory rheumatic diseases (LIFT).

Martin KR, Bachmair EM, Aucott L, Dures E, Emsley R, Gray SR, Hewlett S, Kumar V, Lovell K, Macfarlane GJ, MacLennan G, McNamee P, Norrie J, Paul L, Ralston S, Siebert S, Wearden A, White PD, Basu N.

BMJ Open. 2019 Jan 30;9(1):e026793. doi: 10.1136/bmjopen-2018-026793.


Evidence of a causal relationship between body mass index and psoriasis: A mendelian randomization study.

Budu-Aggrey A, Brumpton B, Tyrrell J, Watkins S, Modalsli EH, Celis-Morales C, Ferguson LD, Vie GÅ, Palmer T, Fritsche LG, Løset M, Nielsen JB, Zhou W, Tsoi LC, Wood AR, Jones SE, Beaumont R, Saunes M, Romundstad PR, Siebert S, McInnes IB, Elder JT, Davey Smith G, Frayling TM, Åsvold BO, Brown SJ, Sattar N, Paternoster L.

PLoS Med. 2019 Jan 31;16(1):e1002739. doi: 10.1371/journal.pmed.1002739. eCollection 2019 Jan.


Voluntary sustainability standards could significantly reduce detrimental impacts of global agriculture.

Smith WK, Nelson E, Johnson JA, Polasky S, Milder JC, Gerber JS, West PC, Siebert S, Brauman KA, Carlson KM, Arbuthnot M, Rozza JP, Pennington DN.

Proc Natl Acad Sci U S A. 2019 Feb 5;116(6):2130-2137. doi: 10.1073/pnas.1707812116. Epub 2019 Jan 22.


Level of adherence to prescribed exercise in spondyloarthritis and factors affecting this adherence: a systematic review.

McDonald MT, Siebert S, Coulter EH, McDonald DA, Paul L.

Rheumatol Int. 2019 Feb;39(2):187-201. doi: 10.1007/s00296-018-4225-8. Epub 2019 Jan 16. Review.


Increased Risk of Hypertension Associated with Spondyloarthritis Disease Duration: Results from the ASAS-COMOSPA Study.

Derakhshan MH, Goodson NJ, Packham JC, Sengupta R, Molto A, Marzo-Ortega H, Siebert S; BRITSpA and COMOSPA Investigators.

J Rheumatol. 2019 Jul;46(7):701-709. doi: 10.3899/jrheum.180538. Epub 2019 Jan 15.


Advancing research paradigms and pathophysiological pathways in psoriatic arthritis and ankylosing spondylitis: Proceedings of the 2017 Platform for the Exchange of Expertise and Research (PEER) meeting.

Abraham S, Barton A, Eder L, Lim A, McGonagle D, McHugh N, Pennington S, Sengupta R, Siebert S, Bowness P, Schafer PH, Cullen E, FitzGerald O.

Semin Arthritis Rheum. 2019 Jun;48(6):1005-1013. doi: 10.1016/j.semarthrit.2018.10.008. Epub 2018 Oct 15. No abstract available.


Neutropaenia in early rheumatoid arthritis: frequency, predicting factors, natural history and outcome.

Fragoulis GE, Paterson C, Gilmour A, Derakhshan MH, McInnes IB, Porter D, Siebert S.

RMD Open. 2018 Oct 8;4(2):e000739. doi: 10.1136/rmdopen-2018-000739. eCollection 2018.


Rheumatoid arthritis and depression: an inflammatory perspective.

Nerurkar L, Siebert S, McInnes IB, Cavanagh J.

Lancet Psychiatry. 2019 Feb;6(2):164-173. doi: 10.1016/S2215-0366(18)30255-4. Epub 2018 Oct 23. Review.


The extending scope of kinase inhibition in immune diseases.

McInnes IB, Siebert S.

Lancet. 2018 Dec 1;392(10162):2328-2331. doi: 10.1016/S0140-6736(18)32600-X. Epub 2018 Oct 22. No abstract available.


Diverging importance of drought stress for maize and winter wheat in Europe.

Webber H, Ewert F, Olesen JE, Müller C, Fronzek S, Ruane AC, Bourgault M, Martre P, Ababaei B, Bindi M, Ferrise R, Finger R, Fodor N, Gabaldón-Leal C, Gaiser T, Jabloun M, Kersebaum KC, Lizaso JI, Lorite IJ, Manceau L, Moriondo M, Nendel C, Rodríguez A, Ruiz-Ramos M, Semenov MA, Siebert S, Stella T, Stratonovitch P, Trombi G, Wallach D.

Nat Commun. 2018 Oct 12;9(1):4249. doi: 10.1038/s41467-018-06525-2.


Why did IL-23p19 inhibition fail in AS: a tale of tissues, trials or translation?

Siebert S, Millar NL, McInnes IB.

Ann Rheum Dis. 2019 Aug;78(8):1015-1018. doi: 10.1136/annrheumdis-2018-213654. Epub 2018 Oct 8. No abstract available.


Detection of Rickettsia monacensis and Rickettsia amblyommatis in ticks collected from dogs in Costa Rica and Nicaragua.

Springer A, Montenegro VM, Schicht S, Wölfel S, Schaper SR, Chitimia-Dobler L, Siebert S, Strube C.

Ticks Tick Borne Dis. 2018 Sep;9(6):1565-1572. doi: 10.1016/j.ttbdis.2018.08.002. Epub 2018 Aug 6.


Influence of co-morbid fibromyalgia on disease activity measures and response to tumour necrosis factor inhibitors in axial spondyloarthritis: results from a UK national register.

Macfarlane GJ, MacDonald RIR, Pathan E, Siebert S, Gaffney K, Choy E, Packham J, Martin KR, Haywood K, Sengupta R, Atzeni F, Jones GT.

Rheumatology (Oxford). 2018 Nov 1;57(11):1982-1990. doi: 10.1093/rheumatology/key206.


Improved phylogenetic resolution within Siphonophora (Cnidaria) with implications for trait evolution.

Munro C, Siebert S, Zapata F, Howison M, Damian-Serrano A, Church SH, Goetz FE, Pugh PR, Haddock SHD, Dunn CW.

Mol Phylogenet Evol. 2018 Oct;127:823-833. doi: 10.1016/j.ympev.2018.06.030. Epub 2018 Jun 22.


Assessing the Likelihood of Gene Flow From Sugarcane (Saccharum Hybrids) to Wild Relatives in South Africa.

Snyman SJ, Komape DM, Khanyi H, van den Berg J, Cilliers D, Lloyd Evans D, Barnard S, Siebert SJ.

Front Bioeng Biotechnol. 2018 Jun 7;6:72. doi: 10.3389/fbioe.2018.00072. eCollection 2018.


Toward Automated Pre-Biopsy Thyroid Cancer Risk Estimation in Ultrasound.

Galimzianova A, Siebert SM, Kamaya A, Desser TS, Rubin DL.

AMIA Annu Symp Proc. 2018 Apr 16;2017:734-741. eCollection 2017.


Perinatal risk factors for asthma in children with allergic rhinitis and grass pollen sensitization.

Yavuz ST, Siebert S, Akin O, Arslan M, Civelek E, Bagci S.

Allergy Asthma Proc. 2018 May 1;39(3):1-7. doi: 10.2500/aap.2018.39.4122.


Two-thirds of global cropland area impacted by climate oscillations.

Heino M, Puma MJ, Ward PJ, Gerten D, Heck V, Siebert S, Kummu M.

Nat Commun. 2018 Mar 28;9(1):1257. doi: 10.1038/s41467-017-02071-5.


Central echogenic areas in thyroid nodules: Diagnostic performance in prediction of papillary cancer.

Siebert SM, Jeffrey RB, Gomez AJ, Kamaya A.

Eur J Radiol. 2018 Apr;101:45-49. doi: 10.1016/j.ejrad.2018.01.029. Epub 2018 Jan 31.


Climate change effect on wheat phenology depends on cultivar change.

Rezaei EE, Siebert S, Hüging H, Ewert F.

Sci Rep. 2018 Mar 20;8(1):4891. doi: 10.1038/s41598-018-23101-2.


Services for spondyloarthritis: a survey of patients and rheumatologists.

Derakhshan MH, Pathak H, Cook D, Dickinson S, Siebert S, Gaffney K; NASS and BRITSpA investigators.

Rheumatology (Oxford). 2018 Jun 1;57(6):987-996. doi: 10.1093/rheumatology/kex518.


The role of the immune system in kidney disease.

Tecklenborg J, Clayton D, Siebert S, Coley SM.

Clin Exp Immunol. 2018 May;192(2):142-150. doi: 10.1111/cei.13119. Epub 2018 Mar 24. Review.


Diagnostic Performance of Margin Features in Thyroid Nodules in Prediction of Malignancy.

Siebert SM, Gomez AJ, Liang T, Tahvildari AM, Desser TS, Jeffrey RB, Kamaya A.

AJR Am J Roentgenol. 2018 Apr;210(4):860-865. doi: 10.2214/AJR.17.18787. Epub 2018 Feb 15.


Comparison of clustering approaches with application to dual colour protein data.

Siebert S, Ickstadt K, Schäfer M, Radon Y, Verveer PJ.

IET Syst Biol. 2018 Feb;12(1):7-17. doi: 10.1049/iet-syb.2017.0019.


Pairwise comparisons across species are problematic when analyzing functional genomic data.

Dunn CW, Zapata F, Munro C, Siebert S, Hejnol A.

Proc Natl Acad Sci U S A. 2018 Jan 16;115(3):E409-E417. doi: 10.1073/pnas.1707515115. Epub 2018 Jan 4.


Multiple and multidimensional transitions from trainee to trained doctor: a qualitative longitudinal study in the UK.

Gordon L, Jindal-Snape D, Morrison J, Muldoon J, Needham G, Siebert S, Rees C.

BMJ Open. 2017 Dec 1;7(11):e018583. doi: 10.1136/bmjopen-2017-018583.


Agomelatine-Related Shift to Mania in a Patient With Recurrent Depressive Disorder.

Kennel J, Baus C, Dogui R, Siebert S, Riemenschneider M.

Prim Care Companion CNS Disord. 2017 Oct 26;19(5). pii: 16l02079. doi: 10.4088/PCC.16l02079. No abstract available.


Genomic and transcriptomic heterogeneity of colorectal tumours arising in Lynch syndrome.

Binder H, Hopp L, Schweiger MR, Hoffmann S, Jühling F, Kerick M, Timmermann B, Siebert S, Grimm C, Nersisyan L, Arakelyan A, Herberg M, Buske P, Loeffler-Wirth H, Rosolowski M, Engel C, Przybilla J, Peifer M, Friedrichs N, Moeslein G, Odenthal M, Hussong M, Peters S, Holzapfel S, Nattermann J, Hueneburg R, Schmiegel W, Royer-Pokora B, Aretz S, Kloth M, Kloor M, Buettner R, Galle J, Loeffler M.

J Pathol. 2017 Oct;243(2):242-254. doi: 10.1002/path.4948. Epub 2017 Sep 5.


Co-Occurrence and Characteristics of Patients With Axial Spondyloarthritis Who Meet Criteria for Fibromyalgia: Results From a UK National Register.

Macfarlane GJ, Barnish MS, Pathan E, Martin KR, Haywood KL, Siebert S, Packham J, Atzeni F, Jones GT.

Arthritis Rheumatol. 2017 Nov;69(11):2144-2150. doi: 10.1002/art.40185.


A new era for collaboration?

Packham JC, Abraham S, Kirkham B, Helliwell P, Siebert S, Korendowych E, Fitzgerald O, Parkinson A, Brookes M, Coates L, McHugh N.

Rheumatology (Oxford). 2018 May 1;57(5):775-776. doi: 10.1093/rheumatology/kex083. No abstract available.


Colony stimulating factor-1 receptor is a central component of the foreign body response to biomaterial implants in rodents and non-human primates.

Doloff JC, Veiseh O, Vegas AJ, Tam HH, Farah S, Ma M, Li J, Bader A, Chiu A, Sadraei A, Aresta-Dasilva S, Griffin M, Jhunjhunwala S, Webber M, Siebert S, Tang K, Chen M, Langan E, Dholokia N, Thakrar R, Qi M, Oberholzer J, Greiner DL, Langer R, Anderson DG.

Nat Mater. 2017 Jun;16(6):671-680. doi: 10.1038/nmat4866. Epub 2017 Mar 20.


Serological detection of antibodies to Anaplasma spp., Borrelia burgdorferi sensu lato and Ehrlichia canis and of Dirofilaria immitis antigen in dogs from Costa Rica.

Montenegro VM, Bonilla MC, Kaminsky D, Romero-Zúñiga JJ, Siebert S, Krämer F.

Vet Parasitol. 2017 Mar 15;236:97-107. doi: 10.1016/j.vetpar.2017.02.009. Epub 2017 Feb 14.


Editorial: Choosing New Targets for Rheumatoid Arthritis Therapeutics: Too Interesting to Fail?

McInnes IB, Porter D, Siebert S.

Arthritis Rheumatol. 2017 Jun;69(6):1131-1134. doi: 10.1002/art.40082. Epub 2017 May 10. No abstract available.

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