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Kinetics Analysis of the Inhibitory Effects of Alpha-Glucosidase and Identification of Compounds from Ganoderma lipsiense Mycelium.

Costa TM, Mayer DA, Siebert DA, Micke GA, Alberton MD, Tavares LBB, de Oliveira D.

Appl Biochem Biotechnol. 2020 Jan 17. doi: 10.1007/s12010-020-03239-4. [Epub ahead of print]


Erratum: Ten Bosch et al. Cold Atmospheric Pressure Plasma Comb-A Physical Approach for Pediculosis Treatment.

Bosch LT, Habedank B, Siebert D.

Int J Environ Res Public Health. 2020 Jan 9;17(2). pii: E450. doi: 10.3390/ijerph17020450.


Anti-inflammatory activity of the epicuticular wax and its isolated compounds catechin and gallocatechin from Eugenia brasiliensis Lam. (Myrtaceae) leaves.

Siebert DA, Paganelli CJ, Queiroz GS, Alberton MD.

Nat Prod Res. 2020 Jan 8:1-4. doi: 10.1080/14786419.2019.1710707. [Epub ahead of print]


Chemical synthesis of tripeptide thioesters for the biotechnological incorporation into the myxobacterial secondary metabolite argyrin via mutasynthesis.

Siebert DCB, Sommer R, Pogorevc D, Hoffmann M, Wenzel SC, Müller R, Titz A.

Beilstein J Org Chem. 2019 Dec 5;15:2922-2929. doi: 10.3762/bjoc.15.286. eCollection 2019.


Phenolic profile by HPLC-ESI-MS/MS of six Brazilian Eugenia species and their potential as cholinesterase inhibitors.

Tenfen A, Vechi G, Cechinel-Zanchett CC, Lorenzett TS, Reginato-Couto CE, Siebert DA, Vitali L, Micke G, Klein-Júnior LC, Cechinel Filho V.

Nat Prod Res. 2019 Nov 4:1-4. doi: 10.1080/14786419.2019.1686369. [Epub ahead of print]


Sorocea guilleminiana Gaudich.: Wound healing activity, action mechanisms, and chemical characterization of the leaf infusion.

Figueiredo FF, Cechinel Filho V, Damazo AS, Arunachalam K, Colodel EM, Ribeiro M, Venturini CL, Oliveira DM, Machado MTM, Pavan E, Paes RL, Tenfen A, Almeida POA, Siebert DA, Vitali L, Macho A, Martins DTO.

J Ethnopharmacol. 2020 Feb 10;248:112307. doi: 10.1016/j.jep.2019.112307. Epub 2019 Oct 16.


Bauhinia forficata link, a Brazilian medicinal plant traditionally used to treat cardiovascular disorders, exerts endothelium-dependent and independent vasorelaxation in thoracic aorta of normotensive and hypertensive rats.

Cechinel-Zanchett CC, da Silva RCMVAF, Tenfen A, Siebert DA, Micke G, Vitali L, Cechinel-Filho V, Faloni de Andrade S, de Souza P.

J Ethnopharmacol. 2019 Oct 28;243:112118. doi: 10.1016/j.jep.2019.112118. Epub 2019 Jul 24.


Exploiting Hydrogenophaga pseudoflava for aerobic syngas-based production of chemicals.

Grenz S, Baumann PT, Rückert C, Nebel BA, Siebert D, Schwentner A, Eikmanns BJ, Hauer B, Kalinowski J, Takors R, Blombach B.

Metab Eng. 2019 Sep;55:220-230. doi: 10.1016/j.ymben.2019.07.006. Epub 2019 Jul 15.


Defined concatenated α6α1β3γ2 GABAA receptor constructs reveal dual action of pyrazoloquinolinone allosteric modulators.

Simeone X, Iorio MT, Siebert DCB, Rehman S, Schnürch M, Mihovilovic MD, Ernst M.

Bioorg Med Chem. 2019 Jul 15;27(14):3167-3178. doi: 10.1016/j.bmc.2019.06.006. Epub 2019 Jun 5.


Kinetic identification of phenolic compounds and potential production of caffeic acid by Ganoderma lipsiense in solid-state fermentation.

Costa TM, Kaufmann V, Paganelli CJ, Siebert DA, Micke GA, Alberton MD, Tavares LBB, de Oliveira D.

Bioprocess Biosyst Eng. 2019 Aug;42(8):1325-1332. doi: 10.1007/s00449-019-02131-8. Epub 2019 Apr 26.


Infographic. International Olympic Committee consensus statement on pain management in athletes: non-pharmacological strategies.

Hainline B, Derman W, Vernec A, Budgett R, Deie M, Dvorak J, Harle CA, Herring S, McNamee M, Meeuwisse W, Moseley GL, Omololu B, Orchard J, Pipe A, Pluim BM, Raeder J, Siebert D, Stewart M, Stuart MC, Turner J, Ware M, Zideman D, Engebretsen L.

Br J Sports Med. 2019 Jun;53(12):785-786. doi: 10.1136/bjsports-2019-100853. Epub 2019 Apr 5. No abstract available.


Cold Atmospheric Pressure Plasma Comb-A Physical Approach for Pediculosis Treatment.

Ten Bosch L, Habedank B, Siebert D, Mrotzek J, Viöl W.

Int J Environ Res Public Health. 2018 Dec 21;16(1). pii: E19. doi: 10.3390/ijerph16010019.


The optimum valine: lysine ratios on performance and carcass traits of male broilers based on different regression approaches.

Agostini PS, Santos RR, Khan DR, Siebert D, van der Aar P.

Poult Sci. 2019 Mar 1;98(3):1310-1320. doi: 10.3382/ps/pey454.


Teriflunomide's Effect on Glia in Experimental Demyelinating Disease: A Neuroimaging and Histologic Study.

Pol S, Sveinsson M, Sudyn M, Babek N, Siebert D, Bertolino N, Modica CM, Preda M, Schweser F, Zivadinov R.

J Neuroimaging. 2019 Jan;29(1):52-61. doi: 10.1111/jon.12561. Epub 2018 Sep 19.


Survival After Exercise-Related Sudden Cardiac Arrest in Young Athletes: Can We Do Better?

Drezner JA, Peterson DF, Siebert DM, Thomas LC, Lopez-Anderson M, Suchsland MZ, Harmon KG, Kucera KL.

Sports Health. 2019 Jan/Feb;11(1):91-98. doi: 10.1177/1941738118799084. Epub 2018 Sep 11.


Antioxidant and antidepressant-like effects of Eugenia catharinensis D. Legrand in an animal model of depression induced by corticosterone.

Barauna SC, Delwing-Dal Magro D, Brueckheimer MB, Maia TP, Sala GABN, Döhler AW, Harger MC, de Melo DFM, de Gasper AL, Alberton MD, Siebert DA, Micke GA, de Albuquerque CAC, Delwing-De Lima D.

Metab Brain Dis. 2018 Dec;33(6):1985-1994. doi: 10.1007/s11011-018-0306-3. Epub 2018 Aug 22.


SAR-Guided Scoring Function and Mutational Validation Reveal the Binding Mode of CGS-8216 at the α1+/γ2- Benzodiazepine Site.

Siebert DCB, Wieder M, Schlener L, Scholze P, Boresch S, Langer T, Schnürch M, Mihovilovic MD, Richter L, Ernst M, Ecker GF.

J Chem Inf Model. 2018 Aug 27;58(8):1682-1696. doi: 10.1021/acs.jcim.8b00199. Epub 2018 Aug 8.


Engineered Flumazenil Recognition Site Provides Mechanistic Insight Governing Benzodiazepine Modulation in GABAA Receptors.

Siebert DCB, Bampali K, Puthenkalam R, Varagic Z, Sarto-Jackson I, Scholze P, Sieghart W, Mihovilovic MD, Schnürch M, Ernst M.

ACS Chem Biol. 2018 Aug 17;13(8):2040-2047. doi: 10.1021/acschembio.8b00145. Epub 2018 Jul 23.


The Use and Abuse of Human Growth Hormone in Sports.

Siebert DM, Rao AL.

Sports Health. 2018 Sep/Oct;10(5):419-426. doi: 10.1177/1941738118782688. Epub 2018 Jun 22. Review.


Development of a production chain from vegetable biowaste to platform chemicals.

Schmidt A, Sturm G, Lapp CJ, Siebert D, Saravia F, Horn H, Ravi PP, Lemmer A, Gescher J.

Microb Cell Fact. 2018 Jun 13;17(1):90. doi: 10.1186/s12934-018-0937-4.


Different Benzodiazepines Bind with Distinct Binding Modes to GABAA Receptors.

Elgarf AA, Siebert DCB, Steudle F, Draxler A, Li G, Huang S, Cook JM, Ernst M, Scholze P.

ACS Chem Biol. 2018 Aug 17;13(8):2033-2039. doi: 10.1021/acschembio.8b00144. Epub 2018 Jul 23.


Etiology of Sudden Cardiac Arrest and Death in US Competitive Athletes: A 2-Year Prospective Surveillance Study.

Peterson DF, Siebert DM, Kucera KL, Thomas LC, Maleszewski JJ, Lopez-Anderson M, Suchsland MZ, Harmon KG, Drezner JA.

Clin J Sport Med. 2018 Apr 9. doi: 10.1097/JSM.0000000000000598. [Epub ahead of print]


Eugenia brasiliensis leaves extract attenuates visceral and somatic inflammatory pain in mice.

Simões RR, Kraus SI, Coelho IS, Dal-Secco D, Siebert DA, Micke GA, Alberton MD, Santos ARS.

J Ethnopharmacol. 2018 May 10;217:178-186. doi: 10.1016/j.jep.2018.02.026. Epub 2018 Feb 17.


Sudden cardiac arrest on the field of play: turning tragedy into a survivable event.

Siebert DM, Drezner JA.

Neth Heart J. 2018 Mar;26(3):115-119. doi: 10.1007/s12471-018-1084-6. Review.


Towards functional selectivity for α6β3γ2 GABAA receptors: a series of novel pyrazoloquinolinones.

Treven M, Siebert DCB, Holzinger R, Bampali K, Fabjan J, Varagic Z, Wimmer L, Steudle F, Scholze P, Schnürch M, Mihovilovic MD, Ernst M.

Br J Pharmacol. 2018 Feb;175(3):419-428. doi: 10.1111/bph.14087. Epub 2017 Dec 22.


iCollections methodology: workflow, results and lessons learned.

Blagoderov V, Penn M, Sadka M, Hine A, Brooks S, Siebert DJ, Sleep C, Cafferty S, Cane E, Martin G, Toloni F, Wing P, Chainey J, Duffell L, Huxley R, Ledger S, McLaughlin C, Mazzetta G, Perera J, Crowther R, Douglas L, Durant J, Scialabba E, Honey M, Huertas B, Howard T, Carter V, Albuquerque S, Paterson G, Kitching IJ.

Biodivers Data J. 2017 Sep 28;(5):e21277. doi: 10.3897/BDJ.5.e21277. eCollection 2017.


iCollections methodology: workflow, results and lessons learned.

Blagoderov V, Penn M, Sadka M, Hine A, Brooks S, Siebert DJ, Sleep C, Cafferty S, Cane E, Martin G, Toloni F, Wing P, Chainey J, Duffell L, Huxley R, Ledger S, McLaughlin C, Mazzetta G, Perera J, Crowther R, Douglas L, Durant J, Honey M, Huertas B, Howard T, Carter V, Albuquerque S, Paterson G, Kitching IJ.

Biodivers Data J. 2017 Sep 25;(5):e19893. doi: 10.3897/BDJ.5.e19893. eCollection 2017.


Hypolipemiant and antioxidant effects of Eugenia brasiliensis in an animal model of coconut oil-induced hypertriglyceridemia.

Lima AB, Delwing-de Lima D, Vieira MR, Poletto MZ, Delwing-Dal Magro D, Barauna SC, Alberton MD, Pereira EM, Pereira NR, Salamaia EM, Siebert DA.

Biomed Pharmacother. 2017 Dec;96:642-649. doi: 10.1016/j.biopha.2017.10.047. Epub 2017 Nov 6.


Gonococcal Prosthetic Joint Infection.

Gassiep I, Gilpin B, Douglas J, Siebert D.

J Bone Jt Infect. 2017 Aug 18;2(3):160-162. doi: 10.7150/jbji.20791. eCollection 2017.


Corynebacterium glutamicum Chassis C1*: Building and Testing a Novel Platform Host for Synthetic Biology and Industrial Biotechnology.

Baumgart M, Unthan S, Kloß R, Radek A, Polen T, Tenhaef N, Müller MF, Küberl A, Siebert D, Brühl N, Marin K, Hans S, Krämer R, Bott M, Kalinowski J, Wiechert W, Seibold G, Frunzke J, Rückert C, Wendisch VF, Noack S.

ACS Synth Biol. 2018 Jan 19;7(1):132-144. doi: 10.1021/acssynbio.7b00261. Epub 2017 Aug 30.


Effect of teriflunomide on cortex-basal ganglia-thalamus (CxBGTh) circuit glutamatergic dysregulation in the Theiler's Murine Encephalomyelitis Virus mouse model of multiple sclerosis.

Modica CM, Schweser F, Sudyn ML, Bertolino N, Preda M, Polak P, Siebert DM, Krawiecki JC, Sveinsson M, Hagemeier J, Dwyer MG, Pol S, Zivadinov R.

PLoS One. 2017 Aug 10;12(8):e0182729. doi: 10.1371/journal.pone.0182729. eCollection 2017.


Characterisation of phenolic compounds of the ethyl acetate fraction from Tabernaemontana catharinensis and its potential antidepressant-like effect.

Pauleti NN, Mello J, Siebert DA, Micke GA, de Albuquerque CAC, Alberton MD, Barauna SC.

Nat Prod Res. 2018 Aug;32(16):1987-1990. doi: 10.1080/14786419.2017.1359167. Epub 2017 Aug 1.


Identification of SPPL2a Inhibitors by Multiparametric Analysis of a High-Content Ultra-High-Throughput Screen.

Zhang X, Götte M, Ibig-Rehm Y, Schuffenhauer A, Kamke M, Beisner D, Guerini D, Siebert D, Bonamy GMC, Gabriel D, Bodendorf U.

SLAS Discov. 2017 Jul 1:2472555217719834. doi: 10.1177/2472555217719834. [Epub ahead of print]


Molecular tools for GABAA receptors: High affinity ligands for β1-containing subtypes.

Simeone X, Siebert DCB, Bampali K, Varagic Z, Treven M, Rehman S, Pyszkowski J, Holzinger R, Steudle F, Scholze P, Mihovilovic MD, Schnürch M, Ernst M.

Sci Rep. 2017 Jul 18;7(1):5674. doi: 10.1038/s41598-017-05757-4.


iCollections - Digitising the British and Irish Butterflies in the Natural History Museum, London.

Paterson G, Albuquerque S, Blagoderov V, Brooks S, Cafferty S, Cane E, Carter V, Chainey J, Crowther R, Douglas L, Durant J, Duffell L, Hine A, Honey M, Huertas B, Howard T, Huxley R, Kitching I, Ledger S, McLaughlin C, Martin G, Mazzetta G, Penn M, Perera J, Sadka M, Scialabba E, Self A, Siebert DJ, Sleep C, Toloni F, Wing P.

Biodivers Data J. 2016 Sep 13;(4):e9559. eCollection 2016.


[The importance of nutrition counselling in veterinary practice].

Siebert D, Schmidt S, Hänse M, Coenen M.

Tierarztl Prax Ausg K Kleintiere Heimtiere. 2016 Jun 16;44(3):158-62. doi: 10.15654/TPK-150551. Epub 2016 Mar 31. German.


Chemical composition and evaluation of the antimicrobial activity of the essential oil from leaves of Eugenia platysema.

Tenfen A, Siebert DA, Yamanaka CN, Mendes de Córdova CM, Scharf DR, Simionatto EL, Alberton MD.

Nat Prod Res. 2016 Sep;30(17):2007-11. doi: 10.1080/14786419.2015.1107056. Epub 2015 Nov 23.


Introducing First-Year Radiology Residents to the ACR at the AMCLC From 2009 to 2013: Summary of Experiences and Five-Year First-Cohort Follow-Up.

Stott DB, McMenomy B, Eckmann D, Smith K, Chauhan A, Brady R, Siebert D, Ansel H.

J Am Coll Radiol. 2016 Jan;13(1):33-7. doi: 10.1016/j.jacr.2015.07.012. Epub 2015 Oct 17.


Judicious application of controls as a cost-effective approach to routine diagnostic PCR testing.

McIver CJ, Er N, Hanrahan J, Siebert D.

Pathology. 2015 Oct;47(6):601-3. doi: 10.1097/PAT.0000000000000306. No abstract available.


Metabolic pathway engineering for production of 1,2-propanediol and 1-propanol by Corynebacterium glutamicum.

Siebert D, Wendisch VF.

Biotechnol Biofuels. 2015 Jun 24;8:91. doi: 10.1186/s13068-015-0269-0. eCollection 2015.


Outcomes Following ABO-Incompatible Kidney Transplantation Performed After Desensitization by Nonantigen-Specific Immunoadsorption.

Becker LE, Siebert D, Süsal C, Opelz G, Leo A, Waldherr R, Macher-Goeppinger S, Schemmer P, Schaefer SM, Klein K, Beimler J, Zeier M, Schwenger V, Morath C.

Transplantation. 2015 Nov;99(11):2364-71. doi: 10.1097/TP.0000000000000753.


Development of the Emergency Medical Services Role Identity Scale (EMS-RIS).

Donnelly EA, Siebert D, Siebert C.

Soc Work Health Care. 2015;54(3):212-33. doi: 10.1080/00981389.2014.999979.


Consistent lattice Boltzmann equations for phase transitions.

Siebert DN, Philippi PC, Mattila KK.

Phys Rev E Stat Nonlin Soft Matter Phys. 2014 Nov;90(5-1):053310. Epub 2014 Nov 24.


Evaluation of seasonal chemical composition, antibacterial, antioxidant and anticholinesterase activity of essential oil from Eugenia brasiliensis Lam.

Siebert DA, Tenfen A, Yamanaka CN, de Cordova CM, Scharf DR, Simionatto EL, Alberton MD.

Nat Prod Res. 2015 Feb;29(3):289-92. doi: 10.1080/14786419.2014.958736. Epub 2014 Sep 15.


Chassis organism from Corynebacterium glutamicum--a top-down approach to identify and delete irrelevant gene clusters.

Unthan S, Baumgart M, Radek A, Herbst M, Siebert D, Brühl N, Bartsch A, Bott M, Wiechert W, Marin K, Hans S, Krämer R, Seibold G, Frunzke J, Kalinowski J, Rückert C, Wendisch VF, Noack S.

Biotechnol J. 2015 Feb;10(2):290-301. doi: 10.1002/biot.201400041. Epub 2014 Oct 8.


Student-run free clinics and complementary curricula.

Putman M, Reddy S, Siebert D, Espinoza J, Jones K.

Med Teach. 2014 Dec;36(12):1087-8. doi: 10.3109/0142159X.2014.917164. Epub 2014 Jul 15. No abstract available.


Two cases of femoral arterial access through a previously placed StarClose clip.

Siebert DR, Misselt A, Hunter D, Cressman E.

J Vasc Interv Radiol. 2013 Sep;24(9):1414-6. doi: 10.1016/j.jvir.2013.04.032. No abstract available.


Vegetative anatomy and micromorphology of Salvia divinorum (Lamiaceae) from Mexico, combined with chromatographic analysis of salvinorin A.

Kowalczuk AP, Raman V, Galal AM, Khan IA, Siebert DJ, Zjawiony JK.

J Nat Med. 2014 Jan;68(1):63-73. doi: 10.1007/s11418-013-0769-9. Epub 2013 Apr 21.


Introducing first-year radiology residents to the ACR at the AMCLC from 2009-2011: the potential impact for ACR and state radiological society memberships.

Brady R, McMenomy B, Chauhan A, Siebert D, Smith K, Eckmann DR.

J Am Coll Radiol. 2013 May;10(5):373-5. doi: 10.1016/j.jacr.2013.01.004. Epub 2013 Feb 23.


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