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Items: 1 to 50 of 236

1.

Potent in vitro activity of the albumin fusion type 1 interferons (albumin-interferon-alpha and albumin-interferon-beta) against RNA viral agents of bioterrorism and the severe acute respiratory syndrome (SARS) virus.

Subramanian GM, Moore PA, Gowen BB, Olsen AL, Barnard DL, Paragas J, Hogan RJ, Sidwell RW.

Chemotherapy. 2008;54(3):176-80. doi: 10.1159/000140361. Epub 2008 Jun 18.

PMID:
18560223
2.

Is the anti-psychotic, 10-(3-(dimethylamino)propyl)phenothiazine (promazine), a potential drug with which to treat SARS infections? Lack of efficacy of promazine on SARS-CoV replication in a mouse model.

Barnard DL, Day CW, Bailey K, Heiner M, Montgomery R, Lauridsen L, Jung KH, Li JK, Chan PK, Sidwell RW.

Antiviral Res. 2008 Aug;79(2):105-13. doi: 10.1016/j.antiviral.2007.12.005. Epub 2008 Jan 11.

3.

The role of cerebellar genes in pathology of autism and schizophrenia.

Fatemi SH, Reutiman TJ, Folsom TD, Sidwell RW.

Cerebellum. 2008;7(3):279-94. doi: 10.1007/s12311-008-0017-0.

PMID:
18418686
4.

Prophylactic and therapeutic intervention of Punta Toro virus (Phlebovirus, Bunyaviridae) infection in hamsters with interferon alfacon-1.

Gowen BB, Wong MH, Jung KH, Blatt LM, Sidwell RW.

Antiviral Res. 2008 Mar;77(3):215-24. doi: 10.1016/j.antiviral.2007.12.002. Epub 2008 Jan 7.

5.

Differential pathogenesis of cowpox virus intranasal infections in mice induced by low and high inoculum volumes and effects of cidofovir treatment.

Smee DF, Gowen BB, Wandersee MK, Wong MH, Skirpstunas RT, Baldwin TJ, Hoopes JD, Sidwell RW.

Int J Antimicrob Agents. 2008 Apr;31(4):352-9. doi: 10.1016/j.ijantimicag.2007.11.013. Epub 2008 Feb 21.

6.

Viral regulation of aquaporin 4, connexin 43, microcephalin and nucleolin.

Fatemi SH, Folsom TD, Reutiman TJ, Sidwell RW.

Schizophr Res. 2008 Jan;98(1-3):163-77. Epub 2007 Nov 9.

7.

Efficacy of N-methanocarbathymidine in treating mice infected intranasally with the IHD and WR strains of vaccinia virus.

Smee DF, Hurst BL, Wong MH, Glazer RI, Rahman A, Sidwell RW.

Antiviral Res. 2007 Nov;76(2):124-9. Epub 2007 Jul 10.

8.

Effect of oral gavage treatment with ZnAL42 and other metallo-ion formulations on influenza A H5N1 and H1N1 virus infections in mice.

Barnard DL, Wong MH, Bailey K, Day CW, Sidwell RW, Hickok SS, Hall TJ.

Antivir Chem Chemother. 2007;18(3):125-32.

PMID:
17626596
9.

In vitro and in vivo activities of T-705 against arenavirus and bunyavirus infections.

Gowen BB, Wong MH, Jung KH, Sanders AB, Mendenhall M, Bailey KW, Furuta Y, Sidwell RW.

Antimicrob Agents Chemother. 2007 Sep;51(9):3168-76. Epub 2007 Jul 2.

10.

Neutralizing viruses in suspensions by copper oxide-based filters.

Borkow G, Sidwell RW, Smee DF, Barnard DL, Morrey JD, Lara-Villegas HH, Shemer-Avni Y, Gabbay J.

Antimicrob Agents Chemother. 2007 Jul;51(7):2605-7. Epub 2007 Apr 30.

11.

Activity of T-1106 in a hamster model of yellow Fever virus infection.

Julander JG, Furuta Y, Shafer K, Sidwell RW.

Antimicrob Agents Chemother. 2007 Jun;51(6):1962-6. Epub 2007 Apr 9.

12.
13.

Correlation between breakdown of the blood-brain barrier and disease outcome of viral encephalitis in mice.

Olsen AL, Morrey JD, Smee DF, Sidwell RW.

Antiviral Res. 2007 Aug;75(2):104-12. Epub 2006 Dec 20.

14.

Prophylactic treatment with recombinant Eimeria protein, alone or in combination with an agonist cocktail, protects mice from Banzi virus infection.

Julander JG, Judge JW, Olsen AL, Rosenberg B, Schafer K, Sidwell RW.

Antiviral Res. 2007 Jul;75(1):14-9. Epub 2006 Dec 4.

15.

Efficacy of orally administered T-705 on lethal avian influenza A (H5N1) virus infections in mice.

Sidwell RW, Barnard DL, Day CW, Smee DF, Bailey KW, Wong MH, Morrey JD, Furuta Y.

Antimicrob Agents Chemother. 2007 Mar;51(3):845-51. Epub 2006 Dec 28.

16.

Antiviral activity of nucleoside analogues against SARS-coronavirus (SARS-coV).

Chu CK, Gadthula S, Chen X, Choo H, Olgen S, Barnard DL, Sidwell RW.

Antivir Chem Chemother. 2006;17(5):285-9.

PMID:
17176633
17.

Evaluation of immunomodulators, interferons and known in vitro SARS-coV inhibitors for inhibition of SARS-coV replication in BALB/c mice.

Barnard DL, Day CW, Bailey K, Heiner M, Montgomery R, Lauridsen L, Chan PK, Sidwell RW.

Antivir Chem Chemother. 2006;17(5):275-84.

PMID:
17176632
18.

Anti-influenza virus activities of 4-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)amino]-N-(4,6-dimethyl-2-pyrimidin-2-yl)benzenesulphonamide and its derivatives.

Selvam P, Murugesh N, Chandramohan M, Sidwell RW, Wandersee MK, Smee DF.

Antivir Chem Chemother. 2006;17(5):269-74.

PMID:
17176631
19.

Effect of exogenous interferon and an interferon inducer on western equine encephalitis virus disease in a hamster model.

Julander JG, Siddharthan V, Blatt LM, Schafer K, Sidwell RW, Morrey JD.

Virology. 2007 Apr 10;360(2):454-60. Epub 2006 Nov 21.

20.

Influenza virus resistance to neuraminidase inhibitors.

Mendel DB, Sidwell RW.

Drug Resist Updat. 1998;1(3):184-9.

PMID:
17092804
21.
22.

Combinatorial ribavirin and interferon alfacon-1 therapy of acute arenaviral disease in hamsters.

Gowen BB, Smee DF, Wong MH, Pace AM, Jung KH, Bailey KW, Blatt LM, Sidwell RW.

Antivir Chem Chemother. 2006;17(4):175-83.

PMID:
17066896
23.

TLR3 deletion limits mortality and disease severity due to Phlebovirus infection.

Gowen BB, Hoopes JD, Wong MH, Jung KH, Isakson KC, Alexopoulou L, Flavell RA, Sidwell RW.

J Immunol. 2006 Nov 1;177(9):6301-7.

24.

Comparison of the inhibitory effects of interferon alfacon-1 and ribavirin on yellow fever virus infection in a hamster model.

Julander JG, Morrey JD, Blatt LM, Shafer K, Sidwell RW.

Antiviral Res. 2007 Feb;73(2):140-6. Epub 2006 Sep 22.

25.

Mutations in the E9L polymerase gene of cidofovir-resistant vaccinia virus strain WR are associated with the drug resistance phenotype.

Kornbluth RS, Smee DF, Sidwell RW, Snarsky V, Evans DH, Hostetler KY.

Antimicrob Agents Chemother. 2006 Dec;50(12):4038-43. Epub 2006 Sep 18.

26.

Respiratory syncytial virus infections: recent prospects for control.

Sidwell RW, Barnard DL.

Antiviral Res. 2006 Sep;71(2-3):379-90. Epub 2006 Jun 9. Review.

PMID:
16806515
27.

Recombinant Eimeria protozoan protein elicits resistance to acute phlebovirus infection in mice but not hamsters.

Gowen BB, Smee DF, Wong MH, Judge JW, Jung KH, Bailey KW, Pace AM, Rosenberg B, Sidwell RW.

Antimicrob Agents Chemother. 2006 Jun;50(6):2023-9.

28.

Cell line dependency for antiviral activity and in vivo efficacy of N-methanocarbathymidine against orthopoxvirus infections in mice.

Smee DF, Wandersee MK, Bailey KW, Wong MH, Chu CK, Gadthula S, Sidwell RW.

Antiviral Res. 2007 Jan;73(1):69-77. Epub 2006 May 5.

PMID:
16712967
29.

Enhancement of the infectivity of SARS-CoV in BALB/c mice by IMP dehydrogenase inhibitors, including ribavirin.

Barnard DL, Day CW, Bailey K, Heiner M, Montgomery R, Lauridsen L, Winslow S, Hoopes J, Li JK, Lee J, Carson DA, Cottam HB, Sidwell RW.

Antiviral Res. 2006 Aug;71(1):53-63. Epub 2006 Mar 24.

PMID:
16621037
30.

Sialidase fusion protein as a novel broad-spectrum inhibitor of influenza virus infection.

Malakhov MP, Aschenbrenner LM, Smee DF, Wandersee MK, Sidwell RW, Gubareva LV, Mishin VP, Hayden FG, Kim DH, Ing A, Campbell ER, Yu M, Fang F.

Antimicrob Agents Chemother. 2006 Apr;50(4):1470-9.

31.

Synthesis of cyclopentenyl carbocyclic nucleosides as potential antiviral agents against orthopoxviruses and SARS.

Cho JH, Bernard DL, Sidwell RW, Kern ER, Chu CK.

J Med Chem. 2006 Feb 9;49(3):1140-8.

PMID:
16451078
32.

Protective immunity against acute phleboviral infection elicited through immunostimulatory cationic liposome-DNA complexes.

Gowen BB, Fairman J, Smee DF, Wong MH, Jung KH, Pace AM, Heiner ML, Bailey KW, Dow SW, Sidwell RW.

Antiviral Res. 2006 Mar;69(3):165-72. Epub 2006 Jan 6.

PMID:
16430975
33.

West Nile virus infection of the placenta.

Julander JG, Winger QA, Rickords LF, Shi PY, Tilgner M, Binduga-Gajewska I, Sidwell RW, Morrey JD.

Virology. 2006 Mar 30;347(1):175-82. Epub 2006 Jan 9.

34.

Broad-spectrum inhibitor of viruses in the Flaviviridae family.

Ojwang JO, Ali S, Smee DF, Morrey JD, Shimasaki CD, Sidwell RW.

Antiviral Res. 2005 Nov;68(2):49-55. Epub 2005 Jul 28.

PMID:
16199098
35.

In vitro and in vivo influenza virus-inhibitory effects of viramidine.

Sidwell RW, Bailey KW, Wong MH, Barnard DL, Smee DF.

Antiviral Res. 2005 Oct;68(1):10-7.

PMID:
16087250
36.

Characterization and treatment of cidofovir-resistant vaccinia (WR strain) virus infections in cell culture and in mice.

Smee DF, Wandersee MK, Bailey KW, Hostetler KY, Holy A, Sidwell RW.

Antivir Chem Chemother. 2005;16(3):203-11.

PMID:
16004083
37.

Error-prone replication of West Nile virus caused by ribavirin.

Day CW, Smee DF, Julander JG, Yamshchikov VF, Sidwell RW, Morrey JD.

Antiviral Res. 2005 Jul;67(1):38-45.

PMID:
15919121
38.

Interferon alfacon-1 protects hamsters from lethal pichinde virus infection.

Gowen BB, Barnard DL, Smee DF, Wong MH, Pace AM, Jung KH, Winslow SG, Bailey KW, Blatt LM, Sidwell RW.

Antimicrob Agents Chemother. 2005 Jun;49(6):2378-86.

40.

Treatment of West Nile virus-infected mice with reactive immunoglobulin reduces fetal titers and increases dam survival.

Julander JG, Winger QA, Olsen AL, Day CW, Sidwell RW, Morrey JD.

Antiviral Res. 2005 Feb;65(2):79-85.

PMID:
15708634
41.

Synthesis of N3,5'-cyclo-4-(beta-D-ribofuranosyl)-vic-triazolo[4,5-b]pyridin-5-one, a novel compound with anti-hepatitis C virus activity.

Wang P, Hollecker L, Pankiewicz KW, Patterson SE, Whitaker T, McBrayer TR, Tharnish PM, Sidwell RW, Stuyver LJ, Otto MJ, Schinazi RF, Watanabe KA.

J Med Chem. 2004 Nov 18;47(24):6100-3.

PMID:
15537363
42.

Treatment of mannan-enhanced influenza B virus infections in mice with oseltamivir, ribavirin and viramidine.

Smee DF, Wandersee MK, Wong MH, Bailey KW, Sidwell RW.

Antivir Chem Chemother. 2004 Sep;15(5):261-8.

PMID:
15535048
43.

Topical cidofovir is more effective than is parenteral therapy for treatment of progressive vaccinia in immunocompromised mice.

Smee DF, Bailey KW, Wong MH, Wandersee MK, Sidwell RW.

J Infect Dis. 2004 Sep 15;190(6):1132-9. Epub 2004 Aug 3.

PMID:
15319864
44.

Modeling hamsters for evaluating West Nile virus therapies.

Morrey JD, Day CW, Julander JG, Olsen AL, Sidwell RW, Cheney CD, Blatt LM.

Antiviral Res. 2004 Jul;63(1):41-50.

PMID:
15196819
45.

Effect of interferon-alpha and interferon-inducers on West Nile virus in mouse and hamster animal models.

Morrey JD, Day CW, Julander JG, Blatt LM, Smee DF, Sidwell RW.

Antivir Chem Chemother. 2004 Mar;15(2):101-9.

PMID:
15185728
46.

Glial fibrillary acidic protein and glutamic acid decarboxylase 65 and 67 kDa proteins are increased in brains of neonatal BALB/c mice following viral infection in utero.

Fatemi SH, Araghi-Niknam M, Laurence JA, Stary JM, Sidwell RW, Lee S.

Schizophr Res. 2004 Jul 1;69(1):121-3. No abstract available.

PMID:
15145478
47.

Effects of four antiviral substances on lethal vaccinia virus (IHD strain) respiratory infections in mice.

Smee DF, Wong MH, Bailey KW, Beadle JR, Hostetler KY, Sidwell RW.

Int J Antimicrob Agents. 2004 May;23(5):430-7.

PMID:
15120719
48.

In vitro activity of expanded-spectrum pyridazinyl oxime ethers related to pirodavir: novel capsid-binding inhibitors with potent antipicornavirus activity.

Barnard DL, Hubbard VD, Smee DF, Sidwell RW, Watson KG, Tucker SP, Reece PA.

Antimicrob Agents Chemother. 2004 May;48(5):1766-72.

49.

Inhibition of severe acute respiratory syndrome-associated coronavirus (SARSCoV) by calpain inhibitors and beta-D-N4-hydroxycytidine.

Barnard DL, Hubbard VD, Burton J, Smee DF, Morrey JD, Otto MJ, Sidwell RW.

Antivir Chem Chemother. 2004 Jan;15(1):15-22.

PMID:
15074711
50.

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