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Items: 1 to 50 of 343

1.

Engineered SH2 domains with tailored specificities and enhanced affinities for phosphoproteome analysis.

Veggiani G, Huang H, Yates BP, Tong J, Kaneko T, Joshi R, Li SS, Moran MF, Gish G, Sidhu SS.

Protein Sci. 2018 Nov 15. doi: 10.1002/pro.3551. [Epub ahead of print]

PMID:
30431205
2.

EPH Profiling of BTIC Populations in Glioblastoma Multiforme Using CyTOF.

Hu AX, Adams JJ, Vora P, Qazi M, Singh SK, Moffat J, Sidhu SS.

Methods Mol Biol. 2019;1869:155-168. doi: 10.1007/978-1-4939-8805-1_14.

PMID:
30324522
3.

L-Ornithine L-Aspartate is Effective and Safe for the Treatment of Hepatic Encephalopathy in Cirrhosis.

Sidhu SS.

J Clin Exp Hepatol. 2018 Sep;8(3):219-221. doi: 10.1016/j.jceh.2018.08.007. Epub 2018 Sep 5. No abstract available.

PMID:
30302036
4.

Generating Intracellular Modulators of E3 Ligases and Deubiquitinases from Phage-Displayed Ubiquitin Variant Libraries.

Zhang W, Sidhu SS.

Methods Mol Biol. 2018;1844:101-119. doi: 10.1007/978-1-4939-8706-1_8.

PMID:
30242706
5.

Intracellular Delivery of Human Purine Nucleoside Phosphorylase by Engineered Diphtheria Toxin Rescues Function in Target Cells.

Park M, Xu X, Min W, Sugiman-Marangos SN, Beilhartz GL, Adams JJ, Sidhu SS, Grunebaum E, Melnyk RA.

Mol Pharm. 2018 Nov 5;15(11):5217-5226. doi: 10.1021/acs.molpharmaceut.8b00735. Epub 2018 Sep 26.

PMID:
30212635
6.

Fc Engineering: Tailored Synthetic Human IgG1-Fc Repertoire for High-Affinity Interaction with FcRn at pH 6.0.

Saxena A, Bai B, Hou SC, Jiang L, Ying T, Miersch S, Sidhu SS, Wu D.

Methods Mol Biol. 2018;1827:399-417. doi: 10.1007/978-1-4939-8648-4_21.

PMID:
30196509
7.

A synthetic anti-Frizzled antibody engineered for broadened specificity exhibits enhanced anti-tumor properties.

Pavlovic Z, Adams JJ, Blazer LL, Gakhal AK, Jarvik N, Steinhart Z, Robitaille M, Mascall K, Pan J, Angers S, Moffat J, Sidhu SS.

MAbs. 2018 Nov-Dec;10(8):1157-1167. doi: 10.1080/19420862.2018.1515565. Epub 2018 Sep 25.

PMID:
30183492
8.

Humanized Mice for the Study of Immuno-Oncology.

De La Rochere P, Guil-Luna S, Decaudin D, Azar G, Sidhu SS, Piaggio E.

Trends Immunol. 2018 Sep;39(9):748-763. doi: 10.1016/j.it.2018.07.001. Epub 2018 Aug 2. Review.

PMID:
30077656
9.

A Structure-Based Strategy for Engineering Selective Ubiquitin Variant Inhibitors of Skp1-Cul1-F-Box Ubiquitin Ligases.

Gorelik M, Manczyk N, Pavlenco A, Kurinov I, Sidhu SS, Sicheri F.

Structure. 2018 Sep 4;26(9):1226-1236.e3. doi: 10.1016/j.str.2018.06.004. Epub 2018 Jul 19.

PMID:
30033217
10.

Host Protein BAG3 is a Negative Regulator of Lassa VLP Egress.

Han Z, Schwoerer MP, Hicks P, Liang J, Ruthel G, Berry CT, Freedman BD, Sagum CA, Bedford MT, Sidhu SS, Sudol M, Harty RN.

Diseases. 2018 Jul 13;6(3). pii: E64. doi: 10.3390/diseases6030064.

11.

Construction of Synthetic Phage Displayed Fab Library with Tailored Diversity.

Huang G, Zhong Z, Miersch S, Sidhu SS, Hou SC, Wu D.

J Vis Exp. 2018 May 1;(135). doi: 10.3791/57357.

PMID:
29782009
12.

Structure-Guided Combinatorial Engineering Facilitates Affinity and Specificity Optimization of Anti-CD81 Antibodies.

Nelson B, Adams J, Kuglstatter A, Li Z, Harris SF, Liu Y, Bohini S, Ma H, Klumpp K, Gao J, Sidhu SS.

J Mol Biol. 2018 Jul 6;430(14):2139-2152. doi: 10.1016/j.jmb.2018.05.018. Epub 2018 May 17.

PMID:
29778602
13.

L-ornithine L-aspartate for prevention and treatment of hepatic encephalopathy in people with cirrhosis.

Goh ET, Stokes CS, Sidhu SS, Vilstrup H, Gluud LL, Morgan MY.

Cochrane Database Syst Rev. 2018 May 15;5:CD012410. doi: 10.1002/14651858.CD012410.pub2. Review.

PMID:
29762873
14.

Corticosteroids Reduce Risk of Death Within 28 Days for Patients With Severe Alcoholic Hepatitis, Compared With Pentoxifylline or Placebo-a Meta-analysis of Individual Data From Controlled Trials.

Louvet A, Thursz MR, Kim DJ, Labreuche J, Atkinson SR, Sidhu SS, O'Grady JG, Akriviadis E, Sinakos E, Carithers RL Jr, Ramond MJ, Maddrey WC, Morgan TR, Duhamel A, Mathurin P.

Gastroenterology. 2018 Aug;155(2):458-468.e8. doi: 10.1053/j.gastro.2018.05.011. Epub 2018 May 5.

PMID:
29738698
15.

Dynamics of PARKIN-Dependent Mitochondrial Ubiquitylation in Induced Neurons and Model Systems Revealed by Digital Snapshot Proteomics.

Ordureau A, Paulo JA, Zhang W, Ahfeldt T, Zhang J, Cohn EF, Hou Z, Heo JM, Rubin LL, Sidhu SS, Gygi SP, Harper JW.

Mol Cell. 2018 Apr 19;70(2):211-227.e8. doi: 10.1016/j.molcel.2018.03.012. Epub 2018 Apr 12.

PMID:
29656925
16.

Sorafenib induced hepatic encephalopathy.

Sidhu SS, Agarwal S, Goyal O, Kishore H, Sidhu S.

Acta Gastroenterol Belg. 2017 Oct-Dec;80(4):537-538.

PMID:
29560652
17.

Electronic Screen Media Use in Youth With Autism Spectrum Disorder.

Gwynette MF, Sidhu SS, Ceranoglu TA.

Child Adolesc Psychiatr Clin N Am. 2018 Apr;27(2):203-219. doi: 10.1016/j.chc.2017.11.013. Review.

PMID:
29502747
18.

Highly multiplexed and quantitative cell-surface protein profiling using genetically barcoded antibodies.

Pollock SB, Hu A, Mou Y, Martinko AJ, Julien O, Hornsby M, Ploder L, Adams JJ, Geng H, Müschen M, Sidhu SS, Moffat J, Wells JA.

Proc Natl Acad Sci U S A. 2018 Mar 13;115(11):2836-2841. doi: 10.1073/pnas.1721899115. Epub 2018 Feb 23.

19.

Drug development: Allosteric inhibitors hit USP7 hard.

Zhang W, Sidhu SS.

Nat Chem Biol. 2018 Jan 16;14(2):110-111. doi: 10.1038/nchembio.2557. No abstract available.

PMID:
29337966
20.

Effects of erythropoietin receptor activity on angiogenesis, tubular injury, and fibrosis in acute kidney injury: a "U-shaped" relationship.

Shi M, Flores B, Li P, Gillings N, McMillan KL, Ye J, Huang LJ, Sidhu SS, Zhong YP, Grompe MT, Streeter PR, Moe OW, Hu MC.

Am J Physiol Renal Physiol. 2018 Apr 1;314(4):F501-F516. doi: 10.1152/ajprenal.00306.2017. Epub 2017 Nov 29.

PMID:
29187371
21.

Inhibition of 53BP1 favors homology-dependent DNA repair and increases CRISPR-Cas9 genome-editing efficiency.

Canny MD, Moatti N, Wan LCK, Fradet-Turcotte A, Krasner D, Mateos-Gomez PA, Zimmermann M, Orthwein A, Juang YC, Zhang W, Noordermeer SM, Seclen E, Wilson MD, Vorobyov A, Munro M, Ernst A, Ng TF, Cho T, Cannon PM, Sidhu SS, Sicheri F, Durocher D.

Nat Biotechnol. 2018 Jan;36(1):95-102. doi: 10.1038/nbt.4021. Epub 2017 Nov 27.

22.

Structural basis for arginine methylation-independent recognition of PIWIL1 by TDRD2.

Zhang H, Liu K, Izumi N, Huang H, Ding D, Ni Z, Sidhu SS, Chen C, Tomari Y, Min J.

Proc Natl Acad Sci U S A. 2017 Nov 21;114(47):12483-12488. doi: 10.1073/pnas.1711486114. Epub 2017 Nov 8.

23.

Construction of Synthetic Antibody Phage-Display Libraries.

Nilvebrant J, Sidhu SS.

Methods Mol Biol. 2018;1701:45-60. doi: 10.1007/978-1-4939-7447-4_3.

PMID:
29116499
24.

The influence of microRNAs and poly(A) tail length on endogenous mRNA-protein complexes.

Rissland OS, Subtelny AO, Wang M, Lugowski A, Nicholson B, Laver JD, Sidhu SS, Smibert CA, Lipshitz HD, Bartel DP.

Genome Biol. 2017 Oct 31;18(1):211. doi: 10.1186/s13059-017-1330-z.

25.

A General Strategy for Discovery of Inhibitors and Activators of RING and U-box E3 Ligases with Ubiquitin Variants.

Gabrielsen M, Buetow L, Nakasone MA, Ahmed SF, Sibbet GJ, Smith BO, Zhang W, Sidhu SS, Huang DT.

Mol Cell. 2017 Oct 19;68(2):456-470.e10. doi: 10.1016/j.molcel.2017.09.027.

26.

Reply.

Sidhu SS, Sharma BC, Goyal O, Kishore H, Kaur N.

Hepatology. 2017 Oct 10. doi: 10.1002/hep.29571. [Epub ahead of print] No abstract available.

PMID:
29023956
27.

A panel of synthetic antibodies that selectively recognize and antagonize members of the interferon alpha family.

Miersch S, Kuruganti S, Walter MR, Sidhu SS.

Protein Eng Des Sel. 2017 Sep 1;30(9):697-704. doi: 10.1093/protein/gzx048.

28.

A synthetic intrabody-based selective and generic inhibitor of GPCR endocytosis.

Ghosh E, Srivastava A, Baidya M, Kumari P, Dwivedi H, Nidhi K, Ranjan R, Dogra S, Koide A, Yadav PN, Sidhu SS, Koide S, Shukla AK.

Nat Nanotechnol. 2017 Dec;12(12):1190-1198. doi: 10.1038/nnano.2017.188. Epub 2017 Oct 2.

29.

Impact of Recent Executive Actions on Minority Youth and Families.

Sidhu SS.

J Am Acad Child Adolesc Psychiatry. 2017 Oct;56(10):805-807. doi: 10.1016/j.jaac.2017.07.779. No abstract available.

PMID:
28942800
30.

U.S. Case Law and Legal Precedent Affirming the Due Process Rights of Immigrants Fleeing Persecution.

Sidhu SS, Boodoo R.

J Am Acad Psychiatry Law. 2017 Sep;45(3):365-373.

PMID:
28939736
31.

A novel immunotherapy targeting MMP-14 limits hypoxia, immune suppression and metastasis in triple-negative breast cancer models.

Ling B, Watt K, Banerjee S, Newsted D, Truesdell P, Adams J, Sidhu SS, Craig AWB.

Oncotarget. 2017 May 9;8(35):58372-58385. doi: 10.18632/oncotarget.17702. eCollection 2017 Aug 29.

32.

Comprehensive Analysis of the Human SH3 Domain Family Reveals a Wide Variety of Non-canonical Specificities.

Teyra J, Huang H, Jain S, Guan X, Dong A, Liu Y, Tempel W, Min J, Tong Y, Kim PM, Bader GD, Sidhu SS.

Structure. 2017 Oct 3;25(10):1598-1610.e3. doi: 10.1016/j.str.2017.07.017. Epub 2017 Sep 7.

33.

Ubiquitin Ligase WWP1 Interacts with Ebola Virus VP40 To Regulate Egress.

Han Z, Sagum CA, Takizawa F, Ruthel G, Berry CT, Kong J, Sunyer JO, Freedman BD, Bedford MT, Sidhu SS, Sudol M, Harty RN.

J Virol. 2017 Sep 27;91(20). pii: e00812-17. doi: 10.1128/JVI.00812-17. Print 2017 Oct 15.

34.

L-ornithine L-aspartate in bouts of overt hepatic encephalopathy.

Sidhu SS, Sharma BC, Goyal O, Kishore H, Kaur N.

Hepatology. 2017 Jul 27. doi: 10.1002/hep.29410. [Epub ahead of print]

PMID:
28749571
35.

Correction: Chaperone-Mediated Autophagy Protein BAG3 Negatively Regulates Ebola and Marburg VP40-Mediated Egress.

Liang J, Sagum CA, Bedford MT, Sidhu SS, Sudol M, Han Z, Harty RN.

PLoS Pathog. 2017 Jul 19;13(7):e1006519. doi: 10.1371/journal.ppat.1006519. eCollection 2017 Jul.

36.

Generation and Validation of Intracellular Ubiquitin Variant Inhibitors for USP7 and USP10.

Zhang W, Sartori MA, Makhnevych T, Federowicz KE, Dong X, Liu L, Nim S, Dong A, Yang J, Li Y, Haddad D, Ernst A, Heerding D, Tong Y, Moffat J, Sidhu SS.

J Mol Biol. 2017 Nov 10;429(22):3546-3560. doi: 10.1016/j.jmb.2017.05.025. Epub 2017 Jun 3.

PMID:
28587923
37.

Specific targeting of the deubiquitinase and E3 ligase families with engineered ubiquitin variants.

Gorelik M, Sidhu SS.

Bioeng Transl Med. 2017 Mar;2(1):31-42. doi: 10.1002/btm2.10044. Epub 2016 Nov 14. Review.

38.

Potent and selective inhibition of pathogenic viruses by engineered ubiquitin variants.

Zhang W, Bailey-Elkin BA, Knaap RCM, Khare B, Dalebout TJ, Johnson GG, van Kasteren PB, McLeish NJ, Gu J, He W, Kikkert M, Mark BL, Sidhu SS.

PLoS Pathog. 2017 May 18;13(5):e1006372. doi: 10.1371/journal.ppat.1006372. eCollection 2017 May.

39.

Intratumoral heterogeneity: pathways to treatment resistance and relapse in human glioblastoma.

Qazi MA, Vora P, Venugopal C, Sidhu SS, Moffat J, Swanton C, Singh SK.

Ann Oncol. 2017 Jul 1;28(7):1448-1456. doi: 10.1093/annonc/mdx169. Review.

PMID:
28407030
40.

Structure-Directed and Tailored Diversity Synthetic Antibody Libraries Yield Novel Anti-EGFR Antagonists.

Miersch S, Maruthachalam BV, Geyer CR, Sidhu SS.

ACS Chem Biol. 2017 May 19;12(5):1381-1389. doi: 10.1021/acschembio.6b00990. Epub 2017 Apr 4.

PMID:
28375604
41.

Treatment of chronic hepatitis C genotype 3 with Sofosbuvir-based therpy: a real-life study.

Sidhu SS, Malhi NS, Goyal O, Singh R, Dutta U, Grover R, Sidhu JS, Nanda V, Saluja H, Bansal A, Singh G, Sehgal A, Kishore H, Sidhu S.

Hepatol Int. 2017 May;11(3):277-285. doi: 10.1007/s12072-017-9794-1. Epub 2017 Mar 31.

PMID:
28361300
42.

Structural and functional characterization of a ubiquitin variant engineered for tight and specific binding to an alpha-helical ubiquitin interacting motif.

Manczyk N, Yates BP, Veggiani G, Ernst A, Sicheri F, Sidhu SS.

Protein Sci. 2017 May;26(5):1060-1069. doi: 10.1002/pro.3155. Epub 2017 Mar 24.

43.

New paradigms in management of alcoholic hepatitis: a review.

Sidhu SS, Goyal O, Kishore H, Sidhu S.

Hepatol Int. 2017 May;11(3):255-267. doi: 10.1007/s12072-017-9790-5. Epub 2017 Feb 28. Review.

PMID:
28247264
44.

Fc Engineering for Developing Therapeutic Bispecific Antibodies and Novel Scaffolds.

Liu H, Saxena A, Sidhu SS, Wu D.

Front Immunol. 2017 Jan 26;8:38. doi: 10.3389/fimmu.2017.00038. eCollection 2017. Review.

45.

Creation of Phosphotyrosine Superbinders by Directed Evolution of an SH2 Domain.

Huang H, Kaneko T, Sidhu SS, Li SS.

Methods Mol Biol. 2017;1555:225-254. doi: 10.1007/978-1-4939-6762-9_13.

PMID:
28092036
46.

Chaperone-Mediated Autophagy Protein BAG3 Negatively Regulates Ebola and Marburg VP40-Mediated Egress.

Liang J, Sagum CA, Bedford MT, Sidhu SS, Sudol M, Han Z, Harty RN.

PLoS Pathog. 2017 Jan 11;13(1):e1006132. doi: 10.1371/journal.ppat.1006132. eCollection 2017 Jan. Erratum in: PLoS Pathog. 2017 Jul 19;13(7):e1006519.

47.

 Minimal hepatic encephalopathy in cirrhosis- how long to treat?

Goyal O, Sidhu SS, Kishore H.

Ann Hepatol. 2017 Jan-Feb 2017;16(1):115-122. doi: 10.5604/16652681.1226822.

48.

Synthetic Antibodies in Infectious Disease.

Chen G, Sidhu SS, Nilvebrant J.

Adv Exp Med Biol. 2017;1053:79-98. doi: 10.1007/978-3-319-72077-7_5. Review.

PMID:
29549636
49.

Fluorescence-based ATG8 sensors monitor localization and function of LC3/GABARAP proteins.

Stolz A, Putyrski M, Kutle I, Huber J, Wang C, Major V, Sidhu SS, Youle RJ, Rogov VV, Dötsch V, Ernst A, Dikic I.

EMBO J. 2017 Feb 15;36(4):549-564. doi: 10.15252/embj.201695063. Epub 2016 Dec 27.

50.

Name No Names: The Role of the Media in Reporting Mass Shootings.

Sidhu SS.

J Am Acad Child Adolesc Psychiatry. 2017 Jan;56(1):3-4. doi: 10.1016/j.jaac.2016.10.004. No abstract available.

PMID:
27993225

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