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Items: 23


Targeting a ceramide double bond improves insulin resistance and hepatic steatosis.

Chaurasia B, Tippetts TS, Mayoral Monibas R, Liu J, Li Y, Wang L, Wilkerson JL, Sweeney CR, Pereira RF, Sumida DH, Maschek JA, Cox JE, Kaddai V, Lancaster GI, Siddique MM, Poss A, Pearson M, Satapati S, Zhou H, McLaren DG, Previs SF, Chen Y, Qian Y, Petrov A, Wu M, Shen X, Yao J, Nunes CN, Howard AD, Wang L, Erion MD, Rutter J, Holland WL, Kelley DE, Summers SA.

Science. 2019 Jul 26;365(6451):386-392. doi: 10.1126/science.aav3722. Epub 2019 Jul 4.


Investigating the histopathologic correlates of 18F-FDG PET heterogeneity in non-small-cell lung cancer.

Bashir U, Foot O, Wise O, Siddique MM, Mclean E, Bille A, Goh V, Cook GJ.

Nucl Med Commun. 2018 Dec;39(12):1197-1206. doi: 10.1097/MNM.0000000000000925.


The effects of segmentation algorithms on the measurement of 18F-FDG PET texture parameters in non-small cell lung cancer.

Bashir U, Azad G, Siddique MM, Dhillon S, Patel N, Bassett P, Landau D, Goh V, Cook G.

EJNMMI Res. 2017 Dec;7(1):60. doi: 10.1186/s13550-017-0310-3. Epub 2017 Jul 26.


Adipocyte Ceramides Regulate Subcutaneous Adipose Browning, Inflammation, and Metabolism.

Chaurasia B, Kaddai VA, Lancaster GI, Henstridge DC, Sriram S, Galam DL, Gopalan V, Prakash KN, Velan SS, Bulchand S, Tsong TJ, Wang M, Siddique MM, Yuguang G, Sigmundsson K, Mellet NA, Weir JM, Meikle PJ, Bin M Yassin MS, Shabbir A, Shayman JA, Hirabayashi Y, Shiow ST, Sugii S, Summers SA.

Cell Metab. 2016 Dec 13;24(6):820-834. doi: 10.1016/j.cmet.2016.10.002. Epub 2016 Nov 3.


Imaging Heterogeneity in Lung Cancer: Techniques, Applications, and Challenges.

Bashir U, Siddique MM, Mclean E, Goh V, Cook GJ.

AJR Am J Roentgenol. 2016 Sep;207(3):534-43. doi: 10.2214/AJR.15.15864. Epub 2016 Jun 15. Review.


Dihydroceramides: From Bit Players to Lead Actors.

Siddique MM, Li Y, Chaurasia B, Kaddai VA, Summers SA.

J Biol Chem. 2015 Jun 19;290(25):15371-9. doi: 10.1074/jbc.R115.653204. Epub 2015 May 6. Review.


Ceramides and glucosylceramides are independent antagonists of insulin signaling.

Chavez JA, Siddique MM, Wang ST, Ching J, Shayman JA, Summers SA.

J Biol Chem. 2014 Jan 10;289(2):723-34. doi: 10.1074/jbc.M113.522847. Epub 2013 Nov 8.


Caffeine stimulates hepatic lipid metabolism by the autophagy-lysosomal pathway in mice.

Sinha RA, Farah BL, Singh BK, Siddique MM, Li Y, Wu Y, Ilkayeva OR, Gooding J, Ching J, Zhou J, Martinez L, Xie S, Bay BH, Summers SA, Newgard CB, Yen PM.

Hepatology. 2014 Apr;59(4):1366-80. doi: 10.1002/hep.26667. Epub 2014 Feb 18.


Ablation of dihydroceramide desaturase 1, a therapeutic target for the treatment of metabolic diseases, simultaneously stimulates anabolic and catabolic signaling.

Siddique MM, Li Y, Wang L, Ching J, Mal M, Ilkayeva O, Wu YJ, Bay BH, Summers SA.

Mol Cell Biol. 2013 Jun;33(11):2353-69. doi: 10.1128/MCB.00226-13. Epub 2013 Apr 1.


Ablation of dihydroceramide desaturase confers resistance to etoposide-induced apoptosis in vitro.

Siddique MM, Bikman BT, Wang L, Ying L, Reinhardt E, Shui G, Wenk MR, Summers SA.

PLoS One. 2012;7(9):e44042. doi: 10.1371/journal.pone.0044042. Epub 2012 Sep 11.


Thyroid hormone stimulates hepatic lipid catabolism via activation of autophagy.

Sinha RA, You SH, Zhou J, Siddique MM, Bay BH, Zhu X, Privalsky ML, Cheng SY, Stevens RD, Summers SA, Newgard CB, Lazar MA, Yen PM.

J Clin Invest. 2012 Jul;122(7):2428-38. doi: 10.1172/JCI60580. Epub 2012 Jun 11.


Fenretinide prevents lipid-induced insulin resistance by blocking ceramide biosynthesis.

Bikman BT, Guan Y, Shui G, Siddique MM, Holland WL, Kim JY, Fabriàs G, Wenk MR, Summers SA.

J Biol Chem. 2012 May 18;287(21):17426-37. doi: 10.1074/jbc.M112.359950. Epub 2012 Apr 2.


Impact of patterns of proteinuria on renal allograft function and survival: a prospective cohort study.

Suhail SM, Kee TS, Woo KT, Tan HK, Yang WS, Chan CM, Foo MW, Li HH, Siddique MM, Wong KS.

Clin Transplant. 2011 May-Jun;25(3):E297-303. doi: 10.1111/j.1399-0012.2011.01415.x. Epub 2011 Mar 1.


Neurochemistry changes associated with mutations in familial Parkinson's disease.

Siddique MM, Tan EK.

Curr Med Chem. 2010;17(35):4378-91. Review.


VHZ is a novel centrosomal phosphatase associated with cell growth and human primary cancers.

Tang JP, Tan CP, Li J, Siddique MM, Guo K, Chan SW, Park JE, Tay WN, Huang ZY, Li WC, Chen J, Zeng Q.

Mol Cancer. 2010 May 28;9:128. doi: 10.1186/1476-4598-9-128.


Quantitative magnetization transfer imaging in Alzheimer disease.

Ridha BH, Tozer DJ, Symms MR, Stockton KC, Lewis EB, Siddique MM, MacManus DG, Rossor MN, Fox NC, Tofts PS.

Radiology. 2007 Sep;244(3):832-7.


Application of automated medial temporal lobe atrophy scale to Alzheimer disease.

Ridha BH, Barnes J, van de Pol LA, Schott JM, Boyes RG, Siddique MM, Rossor MN, Scheltens P, Fox NC.

Arch Neurol. 2007 Jun;64(6):849-54.


Magnetization transfer ratio in Alzheimer disease: comparison with volumetric measurements.

Ridha BH, Symms MR, Tozer DJ, Stockton KC, Frost C, Siddique MM, Lewis EB, MacManus DG, Boulby PA, Barker GJ, Rossor MN, Fox NC, Tofts PS.

AJNR Am J Neuroradiol. 2007 May;28(5):965-70.


An accurate and reproducible scheme for quantification of coronary artery calcification in CT scans.

Dehmeshki J, Ye X, Wang F, Yu Lin X, Abaei M, Siddique MM, Qanadli SD.

Conf Proc IEEE Eng Med Biol Soc. 2004;3:1918-21.


Evidence for selective expression of the p53 codon 72 polymorphs: implications in cancer development.

Siddique MM, Balram C, Fiszer-Maliszewska L, Aggarwal A, Tan A, Tan P, Soo KC, Sabapathy K.

Cancer Epidemiol Biomarkers Prev. 2005 Sep;14(9):2245-52.


Evaluation of the combined effect of p53 codon 72 polymorphism and hotspot mutations in response to anticancer drugs.

Vikhanskaya F, Siddique MM, Kei Lee M, Broggini M, Sabapathy K.

Clin Cancer Res. 2005 Jun 15;11(12):4348-56.


c-Jun regulates the stability and activity of the p53 homologue, p73.

Toh WH, Siddique MM, Boominathan L, Lin KW, Sabapathy K.

J Biol Chem. 2004 Oct 22;279(43):44713-22. Epub 2004 Aug 9.


The recent malaria situation in Chittagong, Bangladesh.

Hussain SM, Rahman MM, Ahmed Z, Siddique MM.

Southeast Asian J Trop Med Public Health. 2003;34 Suppl 2:1-5.


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