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Items: 1 to 50 of 224

1.

Detecting post-translational modification signatures as potential biomarkers in clinical mass spectrometry.

Mnatsakanyan R, Shema G, Basik M, Batist G, Borchers CH, Sickmann A, Zahedi RP.

Expert Rev Proteomics. 2018 Jun;15(6):515-535. doi: 10.1080/14789450.2018.1483340.

PMID:
29893147
2.

Analysis of new growth promoting black market products.

Krug O, Thomas A, Malerød-Fjeld H, Dehnes Y, Laussmann T, Feldmann I, Sickmann A, Thevis M.

Growth Horm IGF Res. 2018 May 19;41:1-6. doi: 10.1016/j.ghir.2018.05.001. [Epub ahead of print]

PMID:
29864719
3.

Advanced tools for the analysis of protein phosphorylation in yeast mitochondria.

Walter C, Gonczarowska-Jorge H, Sickmann A, Zahedi RP, Meisinger C, Schmidt O.

Anal Biochem. 2018 Aug 1;554:23-27. doi: 10.1016/j.ab.2018.05.022. Epub 2018 May 24.

PMID:
29803787
4.

Platelet proteomics: from discovery to diagnosis.

Looße C, Swieringa F, Heemskerk JWM, Sickmann A, Lorenz C.

Expert Rev Proteomics. 2018 Jun;15(6):467-476. doi: 10.1080/14789450.2018.1480111. Epub 2018 Jun 8.

PMID:
29787335
5.

Identification of key lipids critical for platelet activation by comprehensive analysis of the platelet lipidome.

Peng B, Geue S, Coman C, Münzer P, Kopczynski D, Has C, Hoffmann N, Manke MC, Lang F, Sickmann A, Gawaz M, Borst O, Ahrends R.

Blood. 2018 May 21. pii: blood-2017-12-822890. doi: 10.1182/blood-2017-12-822890. [Epub ahead of print]

PMID:
29784642
6.

Omics-based responses induced by bosentan in human hepatoma HepaRG cell cultures.

Rodrigues RM, Kollipara L, Chaudhari U, Sachinidis A, Zahedi RP, Sickmann A, Kopp-Schneider A, Jiang X, Keun H, Hengstler J, Oorts M, Annaert P, Hoeben E, Gijbels E, De Kock J, Vanhaecke T, Rogiers V, Vinken M.

Arch Toxicol. 2018 May 14. doi: 10.1007/s00204-018-2214-z. [Epub ahead of print]

PMID:
29761207
7.

Effects of the NO/soluble guanylate cyclase/cGMP system on the functions of human platelets.

Makhoul S, Walter E, Pagel O, Walter U, Sickmann A, Gambaryan S, Smolenski A, Zahedi RP, Jurk K.

Nitric Oxide. 2018 Jun 1;76:71-80. doi: 10.1016/j.niox.2018.03.008. Epub 2018 Mar 14. Review.

PMID:
29550521
8.

Disentangling thermal stress responses in a reef-calcifier and its photosymbionts by shotgun proteomics.

Stuhr M, Blank-Landeshammer B, Reymond CE, Kollipara L, Sickmann A, Kucera M, Westphal H.

Sci Rep. 2018 Feb 23;8(1):3524. doi: 10.1038/s41598-018-21875-z.

9.

Simple, scalable, and ultrasensitive tip-based identification of protease substrates.

Shema G, Nguyen MTN, Solari FA, Loroch S, Venne AS, Kollipara L, Sickmann A, Verhelst SHL, Zahedi RP.

Mol Cell Proteomics. 2018 Apr;17(4):826-834. doi: 10.1074/mcp.TIR117.000302. Epub 2018 Jan 22.

PMID:
29358340
10.

Quantification of Cardiovascular Disease Biomarkers in Human Platelets by Targeted Mass Spectrometry.

Malchow S, Loosse C, Sickmann A, Lorenz C.

Proteomes. 2017 Nov 15;5(4). pii: E31. doi: 10.3390/proteomes5040031.

11.

Quantifying Missing (Phospho)Proteome Regions with the Broad-Specificity Protease Subtilisin.

Gonczarowska-Jorge H, Loroch S, Dell'Aica M, Sickmann A, Roos A, Zahedi RP.

Anal Chem. 2017 Dec 19;89(24):13137-13145. doi: 10.1021/acs.analchem.7b02395. Epub 2017 Nov 28.

PMID:
29136377
12.

Intersection of Proteomics and Genomics to "Solve the Unsolved" in Rare Disorders such as Neurodegenerative and Neuromuscular Diseases.

Roos A, Thompson R, Horvath R, Lochmüller H, Sickmann A.

Proteomics Clin Appl. 2018 Mar;12(2). doi: 10.1002/prca.201700073. Epub 2017 Oct 23.

PMID:
29059504
13.

Comparison and Evaluation of Clustering Algorithms for Tandem Mass Spectra.

Rieder V, Schork KU, Kerschke L, Blank-Landeshammer B, Sickmann A, Rahnenführer J.

J Proteome Res. 2017 Nov 3;16(11):4035-4044. doi: 10.1021/acs.jproteome.7b00427.

PMID:
28959885
14.

Landscape of submitochondrial protein distribution.

Vögtle FN, Burkhart JM, Gonczarowska-Jorge H, Kücükköse C, Taskin AA, Kopczynski D, Ahrends R, Mossmann D, Sickmann A, Zahedi RP, Meisinger C.

Nat Commun. 2017 Aug 18;8(1):290. doi: 10.1038/s41467-017-00359-0.

15.

Combining De Novo Peptide Sequencing Algorithms, A Synergistic Approach to Boost Both Identifications and Confidence in Bottom-up Proteomics.

Blank-Landeshammer B, Kollipara L, Biß K, Pfenninger M, Malchow S, Shuvaev K, Zahedi RP, Sickmann A.

J Proteome Res. 2017 Sep 1;16(9):3209-3218. doi: 10.1021/acs.jproteome.7b00198. Epub 2017 Aug 22.

PMID:
28741358
16.

Computational proteomics tools for identification and quality control.

Kopczynski D, Sickmann A, Ahrends R.

J Biotechnol. 2017 Nov 10;261:126-130. doi: 10.1016/j.jbiotec.2017.06.1199. Epub 2017 Jul 1. Review.

PMID:
28676234
17.

The FERM protein EPB41L5 regulates actomyosin contractility and focal adhesion formation to maintain the kidney filtration barrier.

Schell C, Rogg M, Suhm M, Helmstädter M, Sellung D, Yasuda-Yamahara M, Kretz O, Küttner V, Suleiman H, Kollipara L, Zahedi RP, Sickmann A, Eimer S, Shaw AS, Kramer-Zucker A, Hirano-Kobayashi M, Abe T, Aizawa S, Grahammer F, Hartleben B, Dengjel J, Huber TB.

Proc Natl Acad Sci U S A. 2017 Jun 6;114(23):E4621-E4630. doi: 10.1073/pnas.1617004114. Epub 2017 May 23.

18.

Activity-based protein profiling as a robust method for enzyme identification and screening in extremophilic Archaea.

Zweerink S, Kallnik V, Ninck S, Nickel S, Verheyen J, Blum M, Wagner A, Feldmann I, Sickmann A, Albers SV, Bräsen C, Kaschani F, Siebers B, Kaiser M.

Nat Commun. 2017 May 8;8:15352. doi: 10.1038/ncomms15352.

19.

LILY-lipidome isotope labeling of yeast: in vivo synthesis of 13C labeled reference lipids for quantification by mass spectrometry.

Rampler E, Coman C, Hermann G, Sickmann A, Ahrends R, Koellensperger G.

Analyst. 2017 Jun 7;142(11):1891-1899. doi: 10.1039/c7an00107j. Epub 2017 May 5.

PMID:
28475182
20.

Tracking Effects of SIL1 Increase: Taking a Closer Look Beyond the Consequences of Elevated Expression Level.

Labisch T, Buchkremer S, Phan V, Kollipara L, Gatz C, Lentz C, Nolte K, Vervoorts J, Coraspe JAG, Sickmann A, Carr S, Zahedi RP, Weis J, Roos A.

Mol Neurobiol. 2018 Mar;55(3):2524-2546. doi: 10.1007/s12035-017-0494-6. Epub 2017 Apr 11.

PMID:
28401474
21.

PeptideMapper: efficient and versatile amino acid sequence and tag mapping.

Kopczynski D, Barsnes H, Njølstad PR, Sickmann A, Vaudel M, Ahrends R.

Bioinformatics. 2017 Jul 1;33(13):2042-2044. doi: 10.1093/bioinformatics/btx122.

PMID:
28334306
22.

DISMS2: A flexible algorithm for direct proteome- wide distance calculation of LC-MS/MS runs.

Rieder V, Blank-Landeshammer B, Stuhr M, Schell T, Biß K, Kollipara L, Meyer A, Pfenninger M, Westphal H, Sickmann A, Rahnenführer J.

BMC Bioinformatics. 2017 Mar 3;18(1):148. doi: 10.1186/s12859-017-1514-2.

23.

The mTOR and PP2A Pathways Regulate PHD2 Phosphorylation to Fine-Tune HIF1α Levels and Colorectal Cancer Cell Survival under Hypoxia.

Di Conza G, Trusso Cafarello S, Loroch S, Mennerich D, Deschoemaeker S, Di Matteo M, Ehling M, Gevaert K, Prenen H, Zahedi RP, Sickmann A, Kietzmann T, Moretti F, Mazzone M.

Cell Rep. 2017 Feb 14;18(7):1699-1712. doi: 10.1016/j.celrep.2017.01.051.

24.

Multi-OMICS: a critical technical perspective on integrative lipidomics approaches.

Kopczynski D, Coman C, Zahedi RP, Lorenz K, Sickmann A, Ahrends R.

Biochim Biophys Acta. 2017 Aug;1862(8):808-811. doi: 10.1016/j.bbalip.2017.02.003. Epub 2017 Feb 11. Review.

PMID:
28193460
25.

Alterations of the platelet proteome in type I Glanzmann thrombasthenia caused by different homozygous delG frameshift mutations in ITGA2B.

Loroch S, Trabold K, Gambaryan S, Reiß C, Schwierczek K, Fleming I, Sickmann A, Behnisch W, Zieger B, Zahedi RP, Walter U, Jurk K.

Thromb Haemost. 2017 Feb 28;117(3):556-569. doi: 10.1160/TH16-07-0515. Epub 2017 Jan 12.

PMID:
28078347
26.

Temporal quantitative phosphoproteomics of ADP stimulation reveals novel central nodes in platelet activation and inhibition.

Beck F, Geiger J, Gambaryan S, Solari FA, Dell'Aica M, Loroch S, Mattheij NJ, Mindukshev I, Pötz O, Jurk K, Burkhart JM, Fufezan C, Heemskerk JW, Walter U, Zahedi RP, Sickmann A.

Blood. 2017 Jan 12;129(2):e1-e12. doi: 10.1182/blood-2016-05-714048. Epub 2016 Nov 9.

27.

Enrichment of Cross-Linked Peptides Using Charge-Based Fractional Diagonal Chromatography (ChaFRADIC).

Tinnefeld V, Venne AS, Sickmann A, Zahedi RP.

J Proteome Res. 2017 Feb 3;16(2):459-469. doi: 10.1021/acs.jproteome.6b00587. Epub 2017 Jan 5.

PMID:
28054782
28.

Deciphering lymphoma pathogenesis via state-of-the-art mass spectrometry-based quantitative proteomics.

Psatha K, Kollipara L, Voutyraki C, Divanach P, Sickmann A, Rassidakis GZ, Drakos E, Aivaliotis M.

J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Mar 15;1047:2-14. doi: 10.1016/j.jchromb.2016.11.005. Epub 2016 Nov 15. Review.

PMID:
27979587
29.

A Ribonucleoprotein Supercomplex Involved in trans-Splicing of Organelle Group II Introns.

Reifschneider O, Marx C, Jacobs J, Kollipara L, Sickmann A, Wolters D, Kück U.

J Biol Chem. 2016 Oct 28;291(44):23330-23342. Epub 2016 Sep 19.

30.

PeptideTracker: A knowledge base for collecting and storing information on protein concentrations in biological tissues.

Mohammed Y, Bhowmick P, Smith DS, Domanski D, Jackson AM, Michaud SA, Malchow S, Percy AJ, Chambers AG, Palmer A, Zhang S, Sickmann A, Borchers CH.

Proteomics. 2017 Apr;17(7). doi: 10.1002/pmic.201600210. Epub 2016 Dec 14. No abstract available.

PMID:
27683069
31.

Bottom-up proteomics suggests an association between differential expression of mitochondrial proteins and chronic fatigue syndrome.

Ciregia F, Kollipara L, Giusti L, Zahedi RP, Giacomelli C, Mazzoni MR, Giannaccini G, Scarpellini P, Urbani A, Sickmann A, Lucacchini A, Bazzichi L.

Transl Psychiatry. 2016 Sep 27;6(9):e904. doi: 10.1038/tp.2016.184.

32.

Global profiling of protein complexes: current approaches and their perspective in biomedical research.

Rudashevskaya EL, Sickmann A, Markoutsa S.

Expert Rev Proteomics. 2016 Sep 19:1-14. [Epub ahead of print]

PMID:
27602509
33.

Combined Quantification of the Global Proteome, Phosphoproteome, and Proteolytic Cleavage to Characterize Altered Platelet Functions in the Human Scott Syndrome.

Solari FA, Mattheij NJ, Burkhart JM, Swieringa F, Collins PW, Cosemans JM, Sickmann A, Heemskerk JW, Zahedi RP.

Mol Cell Proteomics. 2016 Oct;15(10):3154-3169. Epub 2016 Aug 17.

34.

The proteome of baker's yeast mitochondria.

Gonczarowska-Jorge H, Zahedi RP, Sickmann A.

Mitochondrion. 2017 Mar;33:15-21. doi: 10.1016/j.mito.2016.08.007. Epub 2016 Aug 14. Review.

PMID:
27535110
35.

"Watching the Detectives" report of the general assembly of the EU project DETECTIVE Brussels, 24-25 November 2015.

Fernando RN, Chaudhari U, Escher SE, Hengstler JG, Hescheler J, Jennings P, Keun HC, Kleinjans JCS, Kolde R, Kollipara L, Kopp-Schneider A, Limonciel A, Nemade H, Nguemo F, Peterson H, Prieto P, Rodrigues RM, Sachinidis A, Schäfer C, Sickmann A, Spitkovsky D, Stöber R, van Breda SGJ, van de Water B, Vivier M, Zahedi RP, Vinken M, Rogiers V.

Arch Toxicol. 2016 Jun;90(6):1529-1539. doi: 10.1007/s00204-016-1719-6. Epub 2016 Apr 29.

36.

Functional Dissection of an Alternatively Spliced Herpesvirus Gene by Splice Site Mutagenesis.

Schommartz T, Loroch S, Alawi M, Grundhoff A, Sickmann A, Brune W.

J Virol. 2016 Apr 14;90(9):4626-4636. doi: 10.1128/JVI.02987-15. Print 2016 May.

37.

Simultaneous Metabolite, Protein, Lipid Extraction (SIMPLEX): A Combinatorial Multimolecular Omics Approach for Systems Biology.

Coman C, Solari FA, Hentschel A, Sickmann A, Zahedi RP, Ahrends R.

Mol Cell Proteomics. 2016 Apr;15(4):1453-66. doi: 10.1074/mcp.M115.053702. Epub 2016 Jan 26.

38.

Two Birds with One Stone: Parallel Quantification of Proteome and Phosphoproteome Using iTRAQ.

Solari FA, Kollipara L, Sickmann A, Zahedi RP.

Methods Mol Biol. 2016;1394:25-41. doi: 10.1007/978-1-4939-3341-9_3.

PMID:
26700039
39.

A pioneer protein is part of a large complex involved in trans-splicing of a group II intron in the chloroplast of Chlamydomonas reinhardtii.

Lefebvre-Legendre L, Reifschneider O, Kollipara L, Sickmann A, Wolters D, Kück U, Goldschmidt-Clermont M.

Plant J. 2016 Jan;85(1):57-69. doi: 10.1111/tpj.13089.

40.

Conjugation of Ciprofloxacin with Poly(2-oxazoline)s and Polyethylene Glycol via End Groups.

Schmidt M, Harmuth S, Barth ER, Wurm E, Fobbe R, Sickmann A, Krumm C, Tiller JC.

Bioconjug Chem. 2015 Sep 16;26(9):1950-62. doi: 10.1021/acs.bioconjchem.5b00393. Epub 2015 Aug 26.

PMID:
26284608
41.

Mass Spectrometry-Based Proteomics for Relative Protein Quantification and Biomarker Identification in Primary Human Hepatocytes.

Dietz L, Sickmann A.

Methods Mol Biol. 2015;1250:251-65. doi: 10.1007/978-1-4939-2074-7_18.

PMID:
26272148
42.

Defective glycosylation of coagulation factor XII underlies hereditary angioedema type III.

Björkqvist J, de Maat S, Lewandrowski U, Di Gennaro A, Oschatz C, Schönig K, Nöthen MM, Drouet C, Braley H, Nolte MW, Sickmann A, Panousis C, Maas C, Renné T.

J Clin Invest. 2015 Aug 3;125(8):3132-46. doi: 10.1172/JCI77139. Epub 2015 Jul 20.

43.

Current strategies and findings in clinically relevant post-translational modification-specific proteomics.

Pagel O, Loroch S, Sickmann A, Zahedi RP.

Expert Rev Proteomics. 2015 Jun;12(3):235-53. doi: 10.1586/14789450.2015.1042867. Epub 2015 May 8. Review.

44.

Identification of proteins involved in inhibition of spheroid formation under microgravity.

Riwaldt S, Pietsch J, Sickmann A, Bauer J, Braun M, Segerer J, Schwarzwälder A, Aleshcheva G, Corydon TJ, Infanger M, Grimm D.

Proteomics. 2015 Sep;15(17):2945-52. doi: 10.1002/pmic.201500067. Epub 2015 Jun 11.

PMID:
25930030
45.

Why phosphoproteomics is still a challenge.

Solari FA, Dell'Aica M, Sickmann A, Zahedi RP.

Mol Biosyst. 2015 Jun;11(6):1487-93. doi: 10.1039/c5mb00024f.

PMID:
25800119
46.

Multidimensional electrostatic repulsion-hydrophilic interaction chromatography (ERLIC) for quantitative analysis of the proteome and phosphoproteome in clinical and biomedical research.

Loroch S, Schommartz T, Brune W, Zahedi RP, Sickmann A.

Biochim Biophys Acta. 2015 May;1854(5):460-8. doi: 10.1016/j.bbapap.2015.01.006. Epub 2015 Jan 22.

PMID:
25619855
47.

PeptideShaker enables reanalysis of MS-derived proteomics data sets.

Vaudel M, Burkhart JM, Zahedi RP, Oveland E, Berven FS, Sickmann A, Martens L, Barsnes H.

Nat Biotechnol. 2015 Jan;33(1):22-4. doi: 10.1038/nbt.3109. No abstract available.

PMID:
25574629
48.

Highly sensitive phosphoproteomics by tailoring solid-phase extraction to electrostatic repulsion-hydrophilic interaction chromatography.

Loroch S, Zahedi RP, Sickmann A.

Anal Chem. 2015 Feb 3;87(3):1596-604. doi: 10.1021/ac502708m. Epub 2015 Jan 13.

PMID:
25405705
49.

Proteomics--moving from inventory to personalized medicine?

Zahedi RP, Ueffing M, Sickmann A.

Proteomics. 2014 Sep;14(17-18):1953. doi: 10.1002/pmic.201470133. No abstract available.

PMID:
25196382
50.

Amyloid-β peptide induces mitochondrial dysfunction by inhibition of preprotein maturation.

Mossmann D, Vögtle FN, Taskin AA, Teixeira PF, Ring J, Burkhart JM, Burger N, Pinho CM, Tadic J, Loreth D, Graff C, Metzger F, Sickmann A, Kretz O, Wiedemann N, Zahedi RP, Madeo F, Glaser E, Meisinger C.

Cell Metab. 2014 Oct 7;20(4):662-9. doi: 10.1016/j.cmet.2014.07.024. Epub 2014 Aug 28.

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