Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 281

1.

A Mechanism Linking Two Known Vulnerability Factors for Alcohol Abuse: Heightened Alcohol Stimulation and Low Striatal Dopamine D2 Receptors.

Bocarsly ME, da Silva E Silva D, Kolb V, Luderman KD, Shashikiran S, Rubinstein M, Sibley DR, Dobbs LK, Alvarez VA.

Cell Rep. 2019 Oct 29;29(5):1147-1163.e5. doi: 10.1016/j.celrep.2019.09.059.

2.

Happy birthday to Mike-75 years young!

Sibley D.

J Neurosci Res. 2019 Dec;97(12):1744-1745. doi: 10.1002/jnr.24530. No abstract available.

PMID:
31612583
3.

High-potency ligands for DREADD imaging and activation in rodents and monkeys.

Bonaventura J, Eldridge MAG, Hu F, Gomez JL, Sanchez-Soto M, Abramyan AM, Lam S, Boehm MA, Ruiz C, Farrell MR, Moreno A, Galal Faress IM, Andersen N, Lin JY, Moaddel R, Morris PJ, Shi L, Sibley DR, Mahler SV, Nabavi S, Pomper MG, Bonci A, Horti AG, Richmond BJ, Michaelides M.

Nat Commun. 2019 Oct 11;10(1):4627. doi: 10.1038/s41467-019-12236-z.

4.

Differential effects of primary disease and corneal vascularisation on corneal transplant rejection and survival.

Sibley D, Hopkinson CL, Tuft SJ, Kaye SB, Larkin DFP; National Health Service Blood and Transplant Ocular Tissue Advisory Group and contributing ophthalmologists (OTAG Study 26).

Br J Ophthalmol. 2019 Aug 28. pii: bjophthalmol-2019-314200. doi: 10.1136/bjophthalmol-2019-314200. [Epub ahead of print]

PMID:
31462418
5.

Binding potentials for vapour nanobubbles on surfaces using density functional theory.

Yin H, Sibley DN, Archer AJ.

J Phys Condens Matter. 2019 Aug 7;31(31):315102. doi: 10.1088/1361-648X/ab18e8. Epub 2019 Apr 12.

PMID:
30978706
6.

Dopamine D4 Receptor-Selective Compounds Reveal Structure-Activity Relationships that Engender Agonist Efficacy.

Keck TM, Free RB, Day MM, Brown SL, Maddaluna MS, Fountain G, Cooper C, Fallon B, Holmes M, Stang CT, Burkhardt R, Bonifazi A, Ellenberger MP, Newman AH, Sibley DR, Wu C, Boateng CA.

J Med Chem. 2019 Apr 11;62(7):3722-3740. doi: 10.1021/acs.jmedchem.9b00231. Epub 2019 Apr 1.

7.

New roles for dopamine D2 and D3 receptors in pancreatic beta cell insulin secretion.

Farino ZJ, Morgenstern TJ, Maffei A, Quick M, De Solis AJ, Wiriyasermkul P, Freyberg RJ, Aslanoglou D, Sorisio D, Inbar BP, Free RB, Donthamsetti P, Mosharov EV, Kellendonk C, Schwartz GJ, Sibley DR, Schmauss C, Zeltser LM, Moore H, Harris PE, Javitch JA, Freyberg Z.

Mol Psychiatry. 2019 Jan 9. doi: 10.1038/s41380-018-0344-6. [Epub ahead of print]

8.

Remote Scene Size-up Using an Unmanned Aerial Vehicle in a Simulated Mass Casualty Incident.

Sibley AK, Jain TN, Butler M, Nicholson B, Sibley D, Smith D, Atkinson P.

Prehosp Emerg Care. 2019 May-Jun;23(3):332-339. doi: 10.1080/10903127.2018.1511765. Epub 2018 Sep 20.

PMID:
30122093
9.

Johne's disease control programmes.

Orpin P, Sibley D.

Vet Rec. 2018 Aug 18;183(7):224-225. doi: 10.1136/vr.k3496. No abstract available.

PMID:
30120183
10.

Identification of Positive Allosteric Modulators of the D1 Dopamine Receptor That Act at Diverse Binding Sites.

Luderman KD, Conroy JL, Free RB, Southall N, Ferrer M, Sanchez-Soto M, Moritz AE, Willette BKA, Fyfe TJ, Jain P, Titus S, Hazelwood LA, Aubé J, Lane JR, Frankowski KJ, Sibley DR.

Mol Pharmacol. 2018 Oct;94(4):1197-1209. doi: 10.1124/mol.118.113175. Epub 2018 Aug 1.

11.

The pressure tensor across a liquid-vapour interface.

Braga C, Smith ER, Nold A, Sibley DN, Kalliadasis S.

J Chem Phys. 2018 Jul 28;149(4):044705. doi: 10.1063/1.5020991.

12.

A new era of rationally designed antipsychotics.

Sibley DR, Shi L.

Nature. 2018 Mar 8;555(7695):170-172. doi: 10.1038/d41586-018-02328-z. No abstract available.

13.

Structure-Activity Investigation of a G Protein-Biased Agonist Reveals Molecular Determinants for Biased Signaling of the D2 Dopamine Receptor.

Chun LS, Vekariya RH, Free RB, Li Y, Lin DT, Su P, Liu F, Namkung Y, Laporte SA, Moritz AE, Aubé J, Frankowski KJ, Sibley DR.

Front Synaptic Neurosci. 2018 Feb 21;10:2. doi: 10.3389/fnsyn.2018.00002. eCollection 2018.

14.

The E2.65A mutation disrupts dynamic binding poses of SB269652 at the dopamine D2 and D3 receptors.

Verma RK, Abramyan AM, Michino M, Free RB, Sibley DR, Javitch JA, Lane JR, Shi L.

PLoS Comput Biol. 2018 Jan 16;14(1):e1005948. doi: 10.1371/journal.pcbi.1005948. eCollection 2018 Jan.

15.

Irwin J Kopin.

Goldstein DS, Sibley DR.

Neuropsychopharmacology. 2017 Dec;42(13):2656. doi: 10.1038/npp.2017.208. No abstract available.

16.

The Dopamine D5 Receptor Is Involved in Working Memory.

Carr GV, Maltese F, Sibley DR, Weinberger DR, Papaleo F.

Front Pharmacol. 2017 Oct 6;8:666. doi: 10.3389/fphar.2017.00666. eCollection 2017.

17.
18.

Minimally Invasive Redo Mitral Valve Replacement Using a Robotic-Assisted Approach.

Patel H, Lewis CTP, Stephens RL, Angelillo M, Sibley DH.

Innovations (Phila). 2017 Sep/Oct;12(5):375-377. doi: 10.1097/IMI.0000000000000411.

PMID:
29023349
19.

Evaluation of the Rapid Polymyxin NP Test for Polymyxin B Resistance Detection Using Enterobacter cloacae and Enterobacter aerogenes Isolates.

Simar S, Sibley D, Ashcraft D, Pankey G.

J Clin Microbiol. 2017 Oct;55(10):3016-3020. doi: 10.1128/JCM.00934-17. Epub 2017 Jul 26.

20.

Advances and challenges in the search for D2 and D3 dopamine receptor-selective compounds.

Moritz AE, Free RB, Sibley DR.

Cell Signal. 2018 Jan;41:75-81. doi: 10.1016/j.cellsig.2017.07.003. Epub 2017 Jul 14. Review.

21.

Nonequilibrium molecular dynamics simulations of nanoconfined fluids at solid-liquid interfaces.

Morciano M, Fasano M, Nold A, Braga C, Yatsyshin P, Sibley DN, Goddard BD, Chiavazzo E, Asinari P, Kalliadasis S.

J Chem Phys. 2017 Jun 28;146(24):244507. doi: 10.1063/1.4986904.

22.

Films, layers, and droplets: The effect of near-wall fluid structure on spreading dynamics.

Yin H, Sibley DN, Thiele U, Archer AJ.

Phys Rev E. 2017 Feb;95(2-1):023104. doi: 10.1103/PhysRevE.95.023104. Epub 2017 Feb 6.

PMID:
28297907
23.

Synthesis and Pharmacological Characterization of Novel trans-Cyclopropylmethyl-Linked Bivalent Ligands That Exhibit Selectivity and Allosteric Pharmacology at the Dopamine D3 Receptor (D3R).

Kumar V, Moritz AE, Keck TM, Bonifazi A, Ellenberger MP, Sibley CD, Free RB, Shi L, Lane JR, Sibley DR, Newman AH.

J Med Chem. 2017 Feb 23;60(4):1478-1494. doi: 10.1021/acs.jmedchem.6b01688. Epub 2017 Feb 10.

24.

Novel Analogues of (R)-5-(Methylamino)-5,6-dihydro-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one (Sumanirole) Provide Clues to Dopamine D2/D3 Receptor Agonist Selectivity.

Zou MF, Keck TM, Kumar V, Donthamsetti P, Michino M, Burzynski C, Schweppe C, Bonifazi A, Free RB, Sibley DR, Janowsky A, Shi L, Javitch JA, Newman AH.

J Med Chem. 2016 Apr 14;59(7):2973-88. doi: 10.1021/acs.jmedchem.5b01612. Epub 2016 Apr 1.

25.

View From the Capitol.

Sibley D.

Tex Dent J. 2015 Oct;132(10):820-1. No abstract available.

PMID:
26710589
26.

Engaging Students: Using Video Clips of Authentic Client Interactions in Pre-Clinical Veterinary Medical Education.

Hafen M Jr, Siqueira Drake AA, Rush BR, Sibley DS.

J Vet Med Educ. 2015 Fall;42(3):252-8. doi: 10.3138/jvme.0614-059R1. Epub 2015 Jun 15.

PMID:
26075626
27.

High-Resolution Imaging of the Optic Nerve and Retina in Optic Nerve Hypoplasia.

Pilat A, Sibley D, McLean RJ, Proudlock FA, Gottlob I.

Ophthalmology. 2015 Jul;122(7):1330-9. doi: 10.1016/j.ophtha.2015.03.020. Epub 2015 May 1.

28.

Structural basis for Na(+)-sensitivity in dopamine D2 and D3 receptors.

Michino M, Free RB, Doyle TB, Sibley DR, Shi L.

Chem Commun (Camb). 2015 May 21;51(41):8618-21. doi: 10.1039/c5cc02204e.

29.

PNA-Based Multivalent Scaffolds Activate the Dopamine D2 Receptor.

Dix AV, Conroy JL, George Rosenker KM, Sibley DR, Appella DH.

ACS Med Chem Lett. 2015 Mar 13;6(4):425-9. doi: 10.1021/ml500478m. eCollection 2015 Apr 9.

30.

Impact of dialect use on a basic component of learning to read.

Brown MC, Sibley DE, Washington JA, Rogers TT, Edwards JR, MacDonald MC, Seidenberg MS.

Front Psychol. 2015 Mar 24;6:196. doi: 10.3389/fpsyg.2015.00196. eCollection 2015.

31.

Dopamine D1 and D5 receptors differentially regulate oxidative stress through paraoxonase 2 in kidney cells.

Yang S, Yang Y, Yu P, Yang J, Jiang X, Villar VA, Sibley DR, Jose PA, Zeng C.

Free Radic Res. 2015 Apr;49(4):397-410. doi: 10.3109/10715762.2015.1006215. Epub 2015 Mar 5.

32.

Identification of G protein-biased agonists that fail to recruit β-arrestin or promote internalization of the D1 dopamine receptor.

Conroy JL, Free RB, Sibley DR.

ACS Chem Neurosci. 2015 Apr 15;6(4):681-92. doi: 10.1021/acschemneuro.5b00020. Epub 2015 Feb 20.

33.

Investigation of the binding and functional properties of extended length D3 dopamine receptor-selective antagonists.

Furman CA, Roof RA, Moritz AE, Miller BN, Doyle TB, Free RB, Banala AK, Paul NM, Kumar V, Sibley CD, Newman AH, Sibley DR.

Eur Neuropsychopharmacol. 2015 Sep;25(9):1448-61. doi: 10.1016/j.euroneuro.2014.11.013. Epub 2014 Nov 29.

34.

Evidence against dopamine D1/D2 receptor heteromers.

Frederick AL, Yano H, Trifilieff P, Vishwasrao HD, Biezonski D, Mészáros J, Urizar E, Sibley DR, Kellendonk C, Sonntag KC, Graham DL, Colbran RJ, Stanwood GD, Javitch JA.

Mol Psychiatry. 2015 Nov;20(11):1373-85. doi: 10.1038/mp.2014.166. Epub 2015 Jan 6.

35.

Dopamine D₁-like receptors regulate the α₁A-adrenergic receptor in human renal proximal tubule cells and D₁-like dopamine receptor knockout mice.

Ennis RC, Asico LD, Armando I, Yang J, Feranil JB, Jurgens JA, Escano CS Jr, Yu P, Wang X, Sibley DR, Jose PA, Villar VA.

Am J Physiol Renal Physiol. 2014 Dec 1;307(11):F1238-48. doi: 10.1152/ajprenal.00119.2014. Epub 2014 Oct 22.

36.

Responding to nonwords in the lexical decision task: Insights from the English Lexicon Project.

Yap MJ, Sibley DE, Balota DA, Ratcliff R, Rueckl J.

J Exp Psychol Learn Mem Cogn. 2015 May;41(3):597-613. doi: 10.1037/xlm0000064. Epub 2014 Oct 20.

37.

(-)-Stepholidine is a potent pan-dopamine receptor antagonist of both G protein- and β-arrestin-mediated signaling.

Meade JA, Free RB, Miller NR, Chun LS, Doyle TB, Moritz AE, Conroy JL, Watts VJ, Sibley DR.

Psychopharmacology (Berl). 2015 Mar;232(5):917-30. doi: 10.1007/s00213-014-3726-8. Epub 2014 Sep 18.

38.

Discovery and characterization of a G protein-biased agonist that inhibits β-arrestin recruitment to the D2 dopamine receptor.

Free RB, Chun LS, Moritz AE, Miller BN, Doyle TB, Conroy JL, Padron A, Meade JA, Xiao J, Hu X, Dulcey AE, Han Y, Duan L, Titus S, Bryant-Genevier M, Barnaeva E, Ferrer M, Javitch JA, Beuming T, Shi L, Southall NT, Marugan JJ, Sibley DR.

Mol Pharmacol. 2014 Jul;86(1):96-105. doi: 10.1124/mol.113.090563. Epub 2014 Apr 22.

39.

Predict and prevent versus test and treat.

Orpin P, Sibley D.

Vet Rec. 2014 Apr 19;174(16):403-5. doi: 10.1136/vr.g2749. No abstract available.

PMID:
24744294
40.

Discovery, optimization, and characterization of novel D2 dopamine receptor selective antagonists.

Xiao J, Free RB, Barnaeva E, Conroy JL, Doyle T, Miller B, Bryant-Genevier M, Taylor MK, Hu X, Dulcey AE, Southall N, Ferrer M, Titus S, Zheng W, Sibley DR, Marugan JJ.

J Med Chem. 2014 Apr 24;57(8):3450-63. doi: 10.1021/jm500126s. Epub 2014 Apr 10.

41.

Managing endemic infectious disease in cattle herds.

Orpin P, Sibley D.

Vet Rec. 2014 Feb 22;174(8):193-5. doi: 10.1136/vr.g1620. No abstract available.

PMID:
24558215
42.

The Concise Guide to PHARMACOLOGY 2013/14: overview.

Alexander SP, Benson HE, Faccenda E, Pawson AJ, Sharman JL, McGrath JC, Catterall WA, Spedding M, Peters JA, Harmar AJ; CGTP Collaborators, Abul-Hasn N, Anderson CM, Anderson CM, Araiksinen MS, Arita M, Arthofer E, Barker EL, Barratt C, Barnes NM, Bathgate R, Beart PM, Belelli D, Bennett AJ, Birdsall NJ, Boison D, Bonner TI, Brailsford L, Bröer S, Brown P, Calo G, Carter WG, Catterall WA, Chan SL, Chao MV, Chiang N, Christopoulos A, Chun JJ, Cidlowski J, Clapham DE, Cockcroft S, Connor MA, Cox HM, Cuthbert A, Dautzenberg FM, Davenport AP, Dawson PA, Dent G, Dijksterhuis JP, Dollery CT, Dolphin AC, Donowitz M, Dubocovich ML, Eiden L, Eidne K, Evans BA, Fabbro D, Fahlke C, Farndale R, Fitzgerald GA, Fong TM, Fowler CJ, Fry JR, Funk CD, Futerman AH, Ganapathy V, Gaisnier B, Gershengorn MA, Goldin A, Goldman ID, Gundlach AL, Hagenbuch B, Hales TG, Hammond JR, Hamon M, Hancox JC, Hauger RL, Hay DL, Hobbs AJ, Hollenberg MD, Holliday ND, Hoyer D, Hynes NA, Inui KI, Ishii S, Jacobson KA, Jarvis GE, Jarvis MF, Jensen R, Jones CE, Jones RL, Kaibuchi K, Kanai Y, Kennedy C, Kerr ID, Khan AA, Klienz MJ, Kukkonen JP, Lapoint JY, Leurs R, Lingueglia E, Lippiat J, Lolait SJ, Lummis SC, Lynch JW, MacEwan D, Maguire JJ, Marshall IL, May JM, McArdle CA, McGrath JC, Michel MC, Millar NS, Miller LJ, Mitolo V, Monk PN, Moore PK, Moorhouse AJ, Mouillac B, Murphy PM, Neubig RR, Neumaier J, Niesler B, Obaidat A, Offermanns S, Ohlstein E, Panaro MA, Parsons S, Pwrtwee RG, Petersen J, Pin JP, Poyner DR, Prigent S, Prossnitz ER, Pyne NJ, Pyne S, Quigley JG, Ramachandran R, Richelson EL, Roberts RE, Roskoski R, Ross RA, Roth M, Rudnick G, Ryan RM, Said SI, Schild L, Sanger GJ, Scholich K, Schousboe A, Schulte G, Schulz S, Serhan CN, Sexton PM, Sibley DR, Siegel JM, Singh G, Sitsapesan R, Smart TG, Smith DM, Soga T, Stahl A, Stewart G, Stoddart LA, Summers RJ, Thorens B, Thwaites DT, Toll L, Traynor JR, Usdin TB, Vandenberg RJ, Villalon C, Vore M, Waldman SA, Ward DT, Willars GB, Wonnacott SJ, Wright E, Ye RD, Yonezawa A, Zimmermann M.

Br J Pharmacol. 2013 Dec;170(8):1449-58. doi: 10.1111/bph.12444.

43.

View from the capitol.

Sibley D.

Tex Dent J. 2013 Oct;130(10):988-9. No abstract available.

PMID:
24354154
44.

Discovery, optimization, and characterization of a novel series of dopamine D2 versus D3 receptor selective antagonists.

Xiao J, Free RB, Barnaeva E, Conroy J, Doyle T, Bryant-Genevier M, Taylor MK, Southall N, Hu X, Ferrer M, Titus S, Zheng W, Sibley DR, Marugan JJ.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2012 Dec 25 [updated 2013 Sep 3].

45.

Ensuring correct use of technology on farm.

Sibley D.

Vet Rec. 2013 Jun 29;172(26):683-4. doi: 10.1136/vr.f4091. No abstract available.

PMID:
23813034
46.

D1-D2 dopamine receptor synergy promotes calcium signaling via multiple mechanisms.

Chun LS, Free RB, Doyle TB, Huang XP, Rankin ML, Sibley DR.

Mol Pharmacol. 2013 Aug;84(2):190-200. doi: 10.1124/mol.113.085175. Epub 2013 May 16.

47.

On the moving contact line singularity: asymptotics of a diffuse-interface model.

Sibley DN, Nold A, Savva N, Kalliadasis S.

Eur Phys J E Soft Matter. 2013 Mar;36(3):26. doi: 10.1140/epje/i2013-13026-y. Epub 2013 Mar 22.

PMID:
23515762
48.

Easier and earlier detection of lameness in dairy cows.

Sibley D.

Vet Rec. 2012 Nov 17;171(20):499-500. doi: 10.1136/vr.e7595. No abstract available.

PMID:
23161929
49.

18F-fluorodeoxythymidine micro-positron-emission tomography versus 18F-fluorodeoxyglucose micro-positron-emission tomography for in vivo minimal residual disease imaging.

Ekshyyan O, Sibley D, Caldito GC, Sunderland J, Vascoe C, Nathan CA.

Laryngoscope. 2013 Jan;123(1):107-11. doi: 10.1002/lary.23600. Epub 2012 Sep 27.

PMID:
23018799
50.

Management and outcomes of patients with epiphora referred to a specialist ophthalmic plastic unit.

Sibley D, Norris JH, Malhotra R.

Clin Exp Ophthalmol. 2013 Apr;41(3):231-8. doi: 10.1111/j.1442-9071.2012.02866.x. Epub 2012 Oct 30.

PMID:
22957969

Supplemental Content

Loading ...
Support Center