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Items: 22


House dust mites activate nociceptor-mast cell clusters to drive type 2 skin inflammation.

Serhan N, Basso L, Sibilano R, Petitfils C, Meixiong J, Bonnart C, Reber LL, Marichal T, Starkl P, Cenac N, Dong X, Tsai M, Galli SJ, Gaudenzio N.

Nat Immunol. 2019 Oct 7. doi: 10.1038/s41590-019-0493-z. [Epub ahead of print]


Is it time for a new classification of mast cells? What do we know about mast cell heterogeneity?

Frossi B, Mion F, Sibilano R, Danelli L, Pucillo CEM.

Immunol Rev. 2018 Mar;282(1):35-46. doi: 10.1111/imr.12636. Review.


The tyrosine kinase inhibitor imatinib mesylate suppresses uric acid crystal-induced acute gouty arthritis in mice.

Reber LL, Starkl P, Balbino B, Sibilano R, Gaudenzio N, Rogalla S, Sensarn S, Kang D, Raghu H, Sokolove J, Robinson WH, Contag CH, Tsai M, Galli SJ.

PLoS One. 2017 Oct 5;12(10):e0185704. doi: 10.1371/journal.pone.0185704. eCollection 2017.


Imaging protective mast cells in living mice during severe contact hypersensitivity.

Reber LL, Sibilano R, Starkl P, Roers A, Grimbaldeston MA, Tsai M, Gaudenzio N, Galli SJ.

JCI Insight. 2017 May 4;2(9). pii: 92900. doi: 10.1172/jci.insight.92900. eCollection 2017 May 4.


Neutrophil myeloperoxidase diminishes the toxic effects and mortality induced by lipopolysaccharide.

Reber LL, Gillis CM, Starkl P, Jönsson F, Sibilano R, Marichal T, Gaudenzio N, Bérard M, Rogalla S, Contag CH, Bruhns P, Galli SJ.

J Exp Med. 2017 May 1;214(5):1249-1258. doi: 10.1084/jem.20161238. Epub 2017 Apr 6.


Decoupling the Functional Pleiotropy of Stem Cell Factor by Tuning c-Kit Signaling.

Ho CCM, Chhabra A, Starkl P, Schnorr PJ, Wilmes S, Moraga I, Kwon HS, Gaudenzio N, Sibilano R, Wehrman TS, Gakovic M, Sockolosky JT, Tiffany MR, Ring AM, Piehler J, Weissman IL, Galli SJ, Shizuru JA, Garcia KC.

Cell. 2017 Mar 9;168(6):1041-1052.e18. doi: 10.1016/j.cell.2017.02.011.


A TNFRSF14-FcɛRI-mast cell pathway contributes to development of multiple features of asthma pathology in mice.

Sibilano R, Gaudenzio N, DeGorter MK, Reber LL, Hernandez JD, Starkl PM, Zurek OW, Tsai M, Zahner S, Montgomery SB, Roers A, Kronenberg M, Yu M, Galli SJ.

Nat Commun. 2016 Dec 16;7:13696. doi: 10.1038/ncomms13696.


Guanine nucleotide exchange factor RABGEF1 regulates keratinocyte-intrinsic signaling to maintain skin homeostasis.

Marichal T, Gaudenzio N, El Abbas S, Sibilano R, Zurek O, Starkl P, Reber LL, Pirottin D, Kim J, Chambon P, Roers A, Antoine N, Kawakami Y, Kawakami T, Bureau F, Tam SY, Tsai M, Galli SJ.

J Clin Invest. 2016 Dec 1;126(12):4497-4515. doi: 10.1172/JCI86359. Epub 2016 Nov 7.


Different activation signals induce distinct mast cell degranulation strategies.

Gaudenzio N, Sibilano R, Marichal T, Starkl P, Reber LL, Cenac N, McNeil BD, Dong X, Hernandez JD, Sagi-Eisenberg R, Hammel I, Roers A, Valitutti S, Tsai M, Espinosa E, Galli SJ.

J Clin Invest. 2016 Oct 3;126(10):3981-3998. doi: 10.1172/JCI85538. Epub 2016 Sep 19.


Pathways of immediate hypothermia and leukocyte infiltration in an adjuvant-free mouse model of anaphylaxis.

Balbino B, Sibilano R, Starkl P, Marichal T, Gaudenzio N, Karasuyama H, Bruhns P, Tsai M, Reber LL, Galli SJ.

J Allergy Clin Immunol. 2017 Feb;139(2):584-596.e10. doi: 10.1016/j.jaci.2016.05.047. Epub 2016 Jul 17.


IgG subclasses determine pathways of anaphylaxis in mice.

Beutier H, Gillis CM, Iannascoli B, Godon O, England P, Sibilano R, Reber LL, Galli SJ, Cragg MS, Van Rooijen N, Mancardi DA, Bruhns P, Jönsson F.

J Allergy Clin Immunol. 2017 Jan;139(1):269-280.e7. doi: 10.1016/j.jaci.2016.03.028. Epub 2016 Apr 26.


IgE antibodies, FcεRIα, and IgE-mediated local anaphylaxis can limit snake venom toxicity.

Starkl P, Marichal T, Gaudenzio N, Reber LL, Sibilano R, Tsai M, Galli SJ.

J Allergy Clin Immunol. 2016 Jan;137(1):246-257.e11. doi: 10.1016/j.jaci.2015.08.005. Epub 2015 Sep 26.


Analyzing the Functions of Mast Cells In Vivo Using 'Mast Cell Knock-in' Mice.

Gaudenzio N, Sibilano R, Starkl P, Tsai M, Galli SJ, Reber LL.

J Vis Exp. 2015 May 27;(99):e52753. doi: 10.3791/52753.


Potential effector and immunoregulatory functions of mast cells in mucosal immunity.

Reber LL, Sibilano R, Mukai K, Galli SJ.

Mucosal Immunol. 2015 May;8(3):444-63. doi: 10.1038/mi.2014.131. Epub 2015 Feb 11. Review.


Mast cell activation: a complex interplay of positive and negative signaling pathways.

Sibilano R, Frossi B, Pucillo CE.

Eur J Immunol. 2014 Sep;44(9):2558-66. doi: 10.1002/eji.201444546. Epub 2014 Aug 22. Review.


Modulation of FcεRI-dependent mast cell response by OX40L.

Sibilano R, Pucillo C, Frossi B.

Methods Mol Biol. 2014;1155:23-30. doi: 10.1007/978-1-4939-0669-7_3.


Allergic responses and aryl hydrocarbon receptor novel pathway of mast cell activation.

Sibilano R, Pucillo CE, Gri G.

Mol Immunol. 2015 Jan;63(1):69-73. doi: 10.1016/j.molimm.2014.02.015. Epub 2014 Mar 18. Review.


Mast cell: an emerging partner in immune interaction.

Gri G, Frossi B, D'Inca F, Danelli L, Betto E, Mion F, Sibilano R, Pucillo C.

Front Immunol. 2012 May 25;3:120. doi: 10.3389/fimmu.2012.00120. eCollection 2012.


The aryl hydrocarbon receptor modulates acute and late mast cell responses.

Sibilano R, Frossi B, Calvaruso M, Danelli L, Betto E, Dall'Agnese A, Tripodo C, Colombo MP, Pucillo CE, Gri G.

J Immunol. 2012 Jul 1;189(1):120-7. doi: 10.4049/jimmunol.1200009. Epub 2012 May 30.


Modulation of FcεRI-dependent mast cell response by OX40L via Fyn, PI3K, and RhoA.

Sibilano R, Frossi B, Suzuki R, D'Incà F, Gri G, Piconese S, Colombo MP, Rivera J, Pucillo CE.

J Allergy Clin Immunol. 2012 Sep;130(3):751-760.e2. doi: 10.1016/j.jaci.2012.03.032. Epub 2012 May 5.


Technical advance: soluble OX40 molecule mimics regulatory T cell modulatory activity on FcεRI-dependent mast cell degranulation.

Sibilano R, Gri G, Frossi B, Tripodo C, Suzuki R, Rivera J, MacDonald AS, Pucillo CE.

J Leukoc Biol. 2011 Oct;90(4):831-8. doi: 10.1189/jlb.1210651. Epub 2011 Jun 7.


Single-cell dynamics of mast cell-CD4+ CD25+ regulatory T cell interactions.

Frossi B, D'Incà F, Crivellato E, Sibilano R, Gri G, Mongillo M, Danelli L, Maggi L, Pucillo CE.

Eur J Immunol. 2011 Jul;41(7):1872-82. doi: 10.1002/eji.201041300. Epub 2011 Jun 8.

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