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Items: 1 to 50 of 67

1.

Corrigendum: Antagonistic actions of two human Pan3 isoforms on global mRNA turnover.

Chen CA, Zhang Y, Xiang Y, Han L, Shyu AB.

RNA. 2018 Nov;24(11):1607-1612. doi: 10.1261/rna.068387.118. No abstract available.

2.

3' UTR shortening represses tumor-suppressor genes in trans by disrupting ceRNA crosstalk.

Park HJ, Ji P, Kim S, Xia Z, Rodriguez B, Li L, Su J, Chen K, Masamha CP, Baillat D, Fontes-Garfias CR, Shyu AB, Neilson JR, Wagner EJ, Li W.

Nat Genet. 2018 Jun;50(6):783-789. doi: 10.1038/s41588-018-0118-8. Epub 2018 May 21.

3.

Comprehensive Characterization of Alternative Polyadenylation in Human Cancer.

Xiang Y, Ye Y, Lou Y, Yang Y, Cai C, Zhang Z, Mills T, Chen NY, Kim Y, Muge Ozguc F, Diao L, Karmouty-Quintana H, Xia Y, Kellems RE, Chen Z, Blackburn MR, Yoo SH, Shyu AB, Mills GB, Han L.

J Natl Cancer Inst. 2018 Apr 1;110(4):379-389. doi: 10.1093/jnci/djx223.

4.

Correction for Ezzeddine et al., "Evidence Providing New Insights into TOB-Promoted Deadenylation and Supporting a Link between TOB's Deadenylation-Enhancing and Antiproliferative Activities".

Ezzeddine N, Chen CA, Shyu AB.

Mol Cell Biol. 2017 Jun 29;37(14). pii: e00208-17. doi: 10.1128/MCB.00208-17. Print 2017 Jul 15. No abstract available.

5.

Antagonistic actions of two human Pan3 isoforms on global mRNA turnover.

Chen CA, Zhang Y, Xiang Y, Han L, Chang JT, Shyu AB.

RNA. 2017 Sep;23(9):1404-1418. doi: 10.1261/rna.061556.117. Epub 2017 May 30. Erratum in: RNA. 2018 Nov;24(11):1607-1612.

6.

Emerging Themes in Regulation of Global mRNA Turnover in cis.

Chen CA, Shyu AB.

Trends Biochem Sci. 2017 Jan;42(1):16-27. doi: 10.1016/j.tibs.2016.08.014. Epub 2016 Sep 16. Review.

7.

CFIm25 regulates glutaminase alternative terminal exon definition to modulate miR-23 function.

Masamha CP, Xia Z, Peart N, Collum S, Li W, Wagner EJ, Shyu AB.

RNA. 2016 Jun;22(6):830-8. doi: 10.1261/rna.055939.116. Epub 2016 Apr 19.

8.

MiR-26 down-regulates TNF-α/NF-κB signalling and IL-6 expression by silencing HMGA1 and MALT1.

Chen CY, Chang JT, Ho YF, Shyu AB.

Nucleic Acids Res. 2016 May 5;44(8):3772-87. doi: 10.1093/nar/gkw205. Epub 2016 Mar 28.

9.

ROCK inhibition enhances microRNA function by promoting deadenylation of targeted mRNAs via increasing PAIP2 expression.

Yoshikawa T, Wu J, Otsuka M, Kishikawa T, Ohno M, Shibata C, Takata A, Han F, Kang YJ, Chen CY, Shyu AB, Han J, Koike K.

Nucleic Acids Res. 2015 Sep 3;43(15):7577-89. doi: 10.1093/nar/gkv728. Epub 2015 Jul 17.

10.

Study of mRNA turnover never decays.

Shyu AB.

RNA. 2015 Apr;21(4):738-9. doi: 10.1261/rna.050526.115. No abstract available.

11.

Emerging mechanisms of mRNP remodeling regulation.

Chen CY, Shyu AB.

Wiley Interdiscip Rev RNA. 2014 Sep-Oct;5(5):713-22. doi: 10.1002/wrna.1241. Epub 2014 Jun 12. Review.

12.

CFIm25 links alternative polyadenylation to glioblastoma tumour suppression.

Masamha CP, Xia Z, Yang J, Albrecht TR, Li M, Shyu AB, Li W, Wagner EJ.

Nature. 2014 Jun 19;510(7505):412-6. doi: 10.1038/nature13261. Epub 2014 May 11.

13.

Protein segregase meddles in remodeling of mRNA-protein complexes.

Chen CY, Shyu AB.

Genes Dev. 2013 May 1;27(9):980-4. doi: 10.1101/gad.219469.113.

14.

Phosphorylation at intrinsically disordered regions of PAM2 motif-containing proteins modulates their interactions with PABPC1 and influences mRNA fate.

Huang KL, Chadee AB, Chen CY, Zhang Y, Shyu AB.

RNA. 2013 Mar;19(3):295-305. doi: 10.1261/rna.037317.112. Epub 2013 Jan 22.

15.

Deadenylation and P-bodies.

Chen CY, Shyu AB.

Adv Exp Med Biol. 2013;768:183-95. doi: 10.1007/978-1-4614-5107-5_11. Review.

16.

Analysis of interferon-beta mRNA stability control after poly(I:C) stimulation using RNA metabolic labeling by ethynyluridine.

Abe K, Ishigami T, Shyu AB, Ohno S, Umemura S, Yamashita A.

Biochem Biophys Res Commun. 2012 Nov 9;428(1):44-9. doi: 10.1016/j.bbrc.2012.09.144. Epub 2012 Oct 9.

17.
18.

Mechanisms of deadenylation-dependent decay.

Chen CY, Shyu AB.

Wiley Interdiscip Rev RNA. 2011 Mar-Apr;2(2):167-83. doi: 10.1002/wrna.40. Epub 2010 Sep 15. Review.

19.

RNA Foci, CUGBP1, and ZNF9 are the primary targets of the mutant CUG and CCUG repeats expanded in myotonic dystrophies type 1 and type 2.

Jones K, Jin B, Iakova P, Huichalaf C, Sarkar P, Schneider-Gold C, Schoser B, Meola G, Shyu AB, Timchenko N, Timchenko L.

Am J Pathol. 2011 Nov;179(5):2475-89. doi: 10.1016/j.ajpath.2011.07.013. Epub 2011 Sep 1.

20.

Unraveling regulation and new components of human P-bodies through a protein interaction framework and experimental validation.

Zheng D, Chen CY, Shyu AB.

RNA. 2011 Sep;17(9):1619-34. doi: 10.1261/rna.2789611. Epub 2011 Jul 12.

21.

Hu antigen R and tristetraprolin: counter-regulators of rat apical sodium-dependent bile acid transporter by way of effects on messenger RNA stability.

Chen F, Shyu AB, Shneider BL.

Hepatology. 2011 Oct;54(4):1371-8. doi: 10.1002/hep.24496. Epub 2011 Aug 9. Erratum in: Hepatology. 2014 Feb;59(2):740.

22.

HuD stimulates translation via eIF4A.

Chen CY, Shyu AB.

Mol Cell. 2009 Dec 25;36(6):920-1. doi: 10.1016/j.molcel.2009.12.013.

23.

Ago-TNRC6 triggers microRNA-mediated decay by promoting two deadenylation steps.

Chen CY, Zheng D, Xia Z, Shyu AB.

Nat Struct Mol Biol. 2009 Nov;16(11):1160-6. doi: 10.1038/nsmb.1709. Epub 2009 Oct 18.

24.

BTG/TOB factors impact deadenylases.

Mauxion F, Chen CY, Séraphin B, Shyu AB.

Trends Biochem Sci. 2009 Dec;34(12):640-7. doi: 10.1016/j.tibs.2009.07.008. Epub 2009 Oct 12. Review.

25.

Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation.

Fabian MR, Mathonnet G, Sundermeier T, Mathys H, Zipprich JT, Svitkin YV, Rivas F, Jinek M, Wohlschlegel J, Doudna JA, Chen CY, Shyu AB, Yates JR 3rd, Hannon GJ, Filipowicz W, Duchaine TF, Sonenberg N.

Mol Cell. 2009 Sep 24;35(6):868-80. doi: 10.1016/j.molcel.2009.08.004. Epub 2009 Aug 27.

26.

Messenger RNA half-life measurements in mammalian cells.

Chen CY, Ezzeddine N, Shyu AB.

Methods Enzymol. 2008;448:335-57. doi: 10.1016/S0076-6879(08)02617-7.

27.

Coordinated changes in mRNA turnover, translation, and RNA processing bodies in bronchial epithelial cells following inflammatory stimulation.

Zhai Y, Zhong Z, Chen CY, Xia Z, Song L, Blackburn MR, Shyu AB.

Mol Cell Biol. 2008 Dec;28(24):7414-26. doi: 10.1128/MCB.01237-08. Epub 2008 Oct 20.

28.

Poly(A)-binding protein-interacting protein 1 binds to eukaryotic translation initiation factor 3 to stimulate translation.

Martineau Y, Derry MC, Wang X, Yanagiya A, Berlanga JJ, Shyu AB, Imataka H, Gehring K, Sonenberg N.

Mol Cell Biol. 2008 Nov;28(21):6658-67. doi: 10.1128/MCB.00738-08. Epub 2008 Aug 25.

29.

Deadenylation is prerequisite for P-body formation and mRNA decay in mammalian cells.

Zheng D, Ezzeddine N, Chen CY, Zhu W, He X, Shyu AB.

J Cell Biol. 2008 Jul 14;182(1):89-101. doi: 10.1083/jcb.200801196.

30.

Messenger RNA regulation: to translate or to degrade.

Shyu AB, Wilkinson MF, van Hoof A.

EMBO J. 2008 Feb 6;27(3):471-81. doi: 10.1038/sj.emboj.7601977. Review.

31.

Human TOB, an antiproliferative transcription factor, is a poly(A)-binding protein-dependent positive regulator of cytoplasmic mRNA deadenylation.

Ezzeddine N, Chang TC, Zhu W, Yamashita A, Chen CY, Zhong Z, Yamashita Y, Zheng D, Shyu AB.

Mol Cell Biol. 2007 Nov;27(22):7791-801. Epub 2007 Sep 4.

32.

Versatile applications of transcriptional pulsing to study mRNA turnover in mammalian cells.

Chen CY, Yamashita Y, Chang TC, Yamashita A, Zhu W, Zhong Z, Shyu AB.

RNA. 2007 Oct;13(10):1775-86. Epub 2007 Aug 29.

33.

Poly(A) nuclease interacts with the C-terminal domain of polyadenylate-binding protein domain from poly(A)-binding protein.

Siddiqui N, Mangus DA, Chang TC, Palermino JM, Shyu AB, Gehring K.

J Biol Chem. 2007 Aug 24;282(34):25067-75. Epub 2007 Jun 26.

34.

Comparative peptide binding studies of the PABC domains from the ubiquitin-protein isopeptide ligase HYD and poly(A)-binding protein. Implications for HYD function.

Lim NS, Kozlov G, Chang TC, Groover O, Siddiqui N, Volpon L, De Crescenzo G, Shyu AB, Gehring K.

J Biol Chem. 2006 May 19;281(20):14376-82. Epub 2006 Mar 22.

35.

UNRaveling the regulation of dosage compensation.

Shyu AB.

Nat Struct Mol Biol. 2006 Mar;13(3):189-90. No abstract available.

PMID:
16518386
36.

Concerted action of poly(A) nucleases and decapping enzyme in mammalian mRNA turnover.

Yamashita A, Chang TC, Yamashita Y, Zhu W, Zhong Z, Chen CY, Shyu AB.

Nat Struct Mol Biol. 2005 Dec;12(12):1054-63. Epub 2005 Nov 13.

PMID:
16284618
37.

UNR, a new partner of poly(A)-binding protein, plays a key role in translationally coupled mRNA turnover mediated by the c-fos major coding-region determinant.

Chang TC, Yamashita A, Chen CY, Yamashita Y, Zhu W, Durdan S, Kahvejian A, Sonenberg N, Shyu AB.

Genes Dev. 2004 Aug 15;18(16):2010-23.

39.

Regulation of eotaxin gene expression by TNF-alpha and IL-4 through mRNA stabilization: involvement of the RNA-binding protein HuR.

Atasoy U, Curry SL, López de Silanes I, Shyu AB, Casolaro V, Gorospe M, Stellato C.

J Immunol. 2003 Oct 15;171(8):4369-78.

40.

[Regulation of mRNA stability in eukaryotic cells].

Uchida N, Hoshino S, Katada T, Shyu AB.

Tanpakushitsu Kakusan Koso. 2003 Aug;48(11 Suppl):1488-95. Japanese. No abstract available.

PMID:
12931604
42.
43.

RNA surveillance by nuclear scanning?

Wilkinson MF, Shyu AB.

Nat Cell Biol. 2002 Jun;4(6):E144-7. Review.

PMID:
12042827
44.
45.
46.
47.

The double lives of shuttling mRNA binding proteins.

Shyu AB, Wilkinson MF.

Cell. 2000 Jul 21;102(2):135-8. Review. No abstract available.

48.

The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism.

Winzen R, Kracht M, Ritter B, Wilhelm A, Chen CY, Shyu AB, Müller M, Gaestel M, Resch K, Holtmann H.

EMBO J. 1999 Sep 15;18(18):4969-80.

49.
50.

Transcriptional pulsing approaches for analysis of mRNA turnover in mammalian cells.

Loflin PT, Chen CY, Xu N, Shyu AB.

Methods. 1999 Jan;17(1):11-20.

PMID:
10075878

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