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Items: 17


PISD is a mitochondrial disease gene causing skeletal dysplasia, cataracts, and white matter changes.

Zhao T, Goedhart CM, Sam PN, Sabouny R, Lingrell S, Cornish AJ, Lamont RE, Bernier FP, Sinasac D, Parboosingh JS; Care4Rare Canada Consortium, Vance JE, Claypool SM, Innes AM, Shutt TE.

Life Sci Alliance. 2019 Mar 11;2(2). pii: e201900353. doi: 10.26508/lsa.201900353. Print 2019 Apr.


Sex-dependent and chronic alterations in behavior and mitochondrial function in a rat model of pediatric mild traumatic brain injury.

Fraunberger EA, Shutt TE, Esser MJ.

Brain Inj. 2019;33(4):534-542. doi: 10.1080/02699052.2019.1565898. Epub 2019 Jan 19.


Mesenchymal Stem Cells Shift Mitochondrial Dynamics and Enhance Oxidative Phosphorylation in Recipient Cells.

Newell C, Sabouny R, Hittel DS, Shutt TE, Khan A, Klein MS, Shearer J.

Front Physiol. 2018 Nov 13;9:1572. doi: 10.3389/fphys.2018.01572. eCollection 2018.


The Keap1-Nrf2 Stress Response Pathway Promotes Mitochondrial Hyperfusion Through Degradation of the Mitochondrial Fission Protein Drp1.

Sabouny R, Fraunberger E, Geoffrion M, Ng AC, Baird SD, Screaton RA, Milne R, McBride HM, Shutt TE.

Antioxid Redox Signal. 2017 Dec 20;27(18):1447-1459. doi: 10.1089/ars.2016.6855. Epub 2017 Jul 7.


Tissue Specific Impacts of a Ketogenic Diet on Mitochondrial Dynamics in the BTBRT+tf/j Mouse.

Newell C, Shutt TE, Ahn Y, Hittel DS, Khan A, Rho JM, Shearer J.

Front Physiol. 2016 Dec 27;7:654. doi: 10.3389/fphys.2016.00654. eCollection 2016.


Staying cool in difficult times: mitochondrial dynamics, quality control and the stress response.

Shutt TE, McBride HM.

Biochim Biophys Acta. 2013 Feb;1833(2):417-24. doi: 10.1016/j.bbamcr.2012.05.024. Epub 2012 Jun 7. Review.


Mitochondrial stress engages E2F1 apoptotic signaling to cause deafness.

Raimundo N, Song L, Shutt TE, McKay SE, Cotney J, Guan MX, Gilliland TC, Hohuan D, Santos-Sacchi J, Shadel GS.

Cell. 2012 Feb 17;148(4):716-26. doi: 10.1016/j.cell.2011.12.027.


Mitochondrial ribosomal protein L12 selectively associates with human mitochondrial RNA polymerase to activate transcription.

Surovtseva YV, Shutt TE, Cotney J, Cimen H, Chen SY, Koc EC, Shadel GS.

Proc Natl Acad Sci U S A. 2011 Nov 1;108(44):17921-6. doi: 10.1073/pnas.1108852108. Epub 2011 Oct 14.


The core human mitochondrial transcription initiation complex: It only takes two to tango.

Shutt TE, Bestwick M, Shadel GS.

Transcription. 2011 Mar;2(2):55-59.


Core human mitochondrial transcription apparatus is a regulated two-component system in vitro.

Shutt TE, Lodeiro MF, Cotney J, Cameron CE, Shadel GS.

Proc Natl Acad Sci U S A. 2010 Jul 6;107(27):12133-8. doi: 10.1073/pnas.0910581107. Epub 2010 Jun 18.


A compendium of human mitochondrial gene expression machinery with links to disease.

Shutt TE, Shadel GS.

Environ Mol Mutagen. 2010 Jun;51(5):360-79. doi: 10.1002/em.20571. Review.


Ancient mtDNA genetic variants modulate mtDNA transcription and replication.

Suissa S, Wang Z, Poole J, Wittkopp S, Feder J, Shutt TE, Wallace DC, Shadel GS, Mishmar D.

PLoS Genet. 2009 May;5(5):e1000474. doi: 10.1371/journal.pgen.1000474. Epub 2009 May 8.


Expanding the mitochondrial interactome.

Shutt TE, Shadel GS.

Genome Biol. 2007;8(2):203. Review.


Bacteriophage origins of mitochondrial replication and transcription proteins.

Shutt TE, Gray MW.

Trends Genet. 2006 Feb;22(2):90-5. Epub 2005 Dec 20. Review.


An ancient spliceosomal intron in the ribosomal protein L7a gene (Rpl7a) of Giardia lamblia.

Russell AG, Shutt TE, Watkins RF, Gray MW.

BMC Evol Biol. 2005 Aug 18;5:45.

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