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Items: 1 to 50 of 240

1.

Creation and validation of three-dimensional printed models for basic nasal endoscopic training.

Zhuo C, Lei L, Yulin Z, Wentao L, Shuangxia W, Chao W, Yaqian Z, Shuman H, Dong D.

Int Forum Allergy Rhinol. 2019 Jun;9(6):695-701. doi: 10.1002/alr.22306. Epub 2019 Feb 12.

PMID:
30748103
2.

Selection of Legionella Virulence-Related Traits by Environmental Protozoa.

Amaro F, Shuman H.

Methods Mol Biol. 2019;1921:55-78. doi: 10.1007/978-1-4939-9048-1_4.

PMID:
30694485
3.

Gallium disrupts bacterial iron metabolism and has therapeutic effects in mice and humans with lung infections.

Goss CH, Kaneko Y, Khuu L, Anderson GD, Ravishankar S, Aitken ML, Lechtzin N, Zhou G, Czyz DM, McLean K, Olakanmi O, Shuman HA, Teresi M, Wilhelm E, Caldwell E, Salipante SJ, Hornick DB, Siehnel RJ, Becker L, Britigan BE, Singh PK.

Sci Transl Med. 2018 Sep 26;10(460). pii: eaat7520. doi: 10.1126/scitranslmed.aat7520.

PMID:
30257953
4.

Obesity and Insulin Resistance Promote Atherosclerosis through an IFNγ-Regulated Macrophage Protein Network.

Reardon CA, Lingaraju A, Schoenfelt KQ, Zhou G, Cui C, Jacobs-El H, Babenko I, Hoofnagle A, Czyz D, Shuman H, Vaisar T, Becker L.

Cell Rep. 2018 Jun 5;23(10):3021-3030. doi: 10.1016/j.celrep.2018.05.010.

5.

High-resolution cryo-EM structures of actin-bound myosin states reveal the mechanism of myosin force sensing.

Mentes A, Huehn A, Liu X, Zwolak A, Dominguez R, Shuman H, Ostap EM, Sindelar CV.

Proc Natl Acad Sci U S A. 2018 Feb 6;115(6):1292-1297. doi: 10.1073/pnas.1718316115. Epub 2018 Jan 22.

6.

Adhesion force and attachment lifetime of the KIF16B-PX domain interaction with lipid membranes.

Pyrpassopoulos S, Shuman H, Ostap EM.

Mol Biol Cell. 2017 Nov 7;28(23):3315-3322. doi: 10.1091/mbc.E17-05-0324. Epub 2017 Sep 20.

7.

GigA and GigB are Master Regulators of Antibiotic Resistance, Stress Responses, and Virulence in Acinetobacter baumannii.

Gebhardt MJ, Shuman HA.

J Bacteriol. 2017 Apr 25;199(10). pii: e00066-17. doi: 10.1128/JB.00066-17. Print 2017 May 15.

8.

Seeing red; the development of pON.mCherry, a broad-host range constitutive expression plasmid for Gram-negative bacteria.

Gebhardt MJ, Jacobson RK, Shuman HA.

PLoS One. 2017 Mar 3;12(3):e0173116. doi: 10.1371/journal.pone.0173116. eCollection 2017.

9.

Measuring the Kinetic and Mechanical Properties of Non-processive Myosins Using Optical Tweezers.

Greenberg MJ, Shuman H, Ostap EM.

Methods Mol Biol. 2017;1486:483-509. doi: 10.1007/978-1-4939-6421-5_19.

10.

A dual-targeting approach to inhibit Brucella abortus replication in human cells.

Czyż DM, Jain-Gupta N, Shuman HA, Crosson S.

Sci Rep. 2016 Oct 21;6:35835. doi: 10.1038/srep35835.

11.

Direct targeting of membrane fusion by SNARE mimicry: Convergent evolution of Legionella effectors.

Shi X, Halder P, Yavuz H, Jahn R, Shuman HA.

Proc Natl Acad Sci U S A. 2016 Aug 2;113(31):8807-12. doi: 10.1073/pnas.1608755113. Epub 2016 Jul 19.

12.

Force Generation by Membrane-Associated Myosin-I.

Pyrpassopoulos S, Arpağ G, Feeser EA, Shuman H, Tüzel E, Ostap EM.

Sci Rep. 2016 May 9;6:25524. doi: 10.1038/srep25524.

13.

Genomic analysis of 38 Legionella species identifies large and diverse effector repertoires.

Burstein D, Amaro F, Zusman T, Lifshitz Z, Cohen O, Gilbert JA, Pupko T, Shuman HA, Segal G.

Nat Genet. 2016 Feb;48(2):167-75. doi: 10.1038/ng.3481. Epub 2016 Jan 11.

14.

Joint Transcriptional Control of Virulence and Resistance to Antibiotic and Environmental Stress in Acinetobacter baumannii.

Gebhardt MJ, Gallagher LA, Jacobson RK, Usacheva EA, Peterson LR, Zurawski DV, Shuman HA.

MBio. 2015 Nov 10;6(6):e01660-15. doi: 10.1128/mBio.01660-15.

15.

Mechanochemical tuning of myosin-I by the N-terminal region.

Greenberg MJ, Lin T, Shuman H, Ostap EM.

Proc Natl Acad Sci U S A. 2015 Jun 30;112(26):E3337-44. doi: 10.1073/pnas.1506633112. Epub 2015 Jun 8.

16.

Diverse protist grazers select for virulence-related traits in Legionella.

Amaro F, Wang W, Gilbert JA, Anderson OR, Shuman HA.

ISME J. 2015 Jul;9(7):1607-18. doi: 10.1038/ismej.2014.248. Epub 2015 Jan 9.

17.

Inherent force-dependent properties of β-cardiac myosin contribute to the force-velocity relationship of cardiac muscle.

Greenberg MJ, Shuman H, Ostap EM.

Biophys J. 2014 Dec 16;107(12):L41-L44. doi: 10.1016/j.bpj.2014.11.005.

18.

Genetic Manipulation of Acinetobacter baumannii.

Jacobs AC, Thompson MG, Gebhardt M, Corey BW, Yildirim S, Shuman HA, Zurawski DV.

Curr Protoc Microbiol. 2014 Nov 3;35:6G.2.1-11. doi: 10.1002/9780471729259.mc06g02s35.

PMID:
25367274
19.

Host-directed antimicrobial drugs with broad-spectrum efficacy against intracellular bacterial pathogens.

Czyż DM, Potluri LP, Jain-Gupta N, Riley SP, Martinez JJ, Steck TL, Crosson S, Shuman HA, Gabay JE.

MBio. 2014 Jul 29;5(4):e01534-14. doi: 10.1128/mBio.01534-14.

20.

Identification of novel Coxiella burnetii Icm/Dot effectors and genetic analysis of their involvement in modulating a mitogen-activated protein kinase pathway.

Lifshitz Z, Burstein D, Schwartz K, Shuman HA, Pupko T, Segal G.

Infect Immun. 2014 Sep;82(9):3740-52. doi: 10.1128/IAI.01729-14. Epub 2014 Jun 23.

21.

A vertebrate myosin-I structure reveals unique insights into myosin mechanochemical tuning.

Shuman H, Greenberg MJ, Zwolak A, Lin T, Sindelar CV, Dominguez R, Ostap EM.

Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):2116-21. doi: 10.1073/pnas.1321022111. Epub 2014 Jan 27.

22.

Method for measuring single-molecule adhesion forces and attachment lifetimes of protein-membrane interactions.

Pyrpassopoulos S, Shuman H, Ostap EM.

Methods Mol Biol. 2013;1046:389-403. doi: 10.1007/978-1-62703-538-5_24.

PMID:
23868602
23.

Analysis of the transcriptome of Legionella pneumophila hfq mutant reveals a new mobile genetic element.

Trigui H, Dudyk P, Sum J, Shuman HA, Faucher SP.

Microbiology. 2013 Aug;159(Pt 8):1649-60. doi: 10.1099/mic.0.067983-0. Epub 2013 May 31.

24.

A bacterial protein promotes the recognition of the Legionella pneumophila vacuole by autophagy.

Khweek AA, Caution K, Akhter A, Abdulrahman BA, Tazi M, Hassan H, Majumdar N, Doran A, Guirado E, Schlesinger LS, Shuman H, Amer AO.

Eur J Immunol. 2013 May;43(5):1333-44. doi: 10.1002/eji.201242835. Epub 2013 Apr 8.

25.

Legionella pneumophila transcriptional response following exposure to CuO nanoparticles.

Lu J, Struewing I, Buse HY, Kou J, Shuman HA, Faucher SP, Ashbolt NJ.

Appl Environ Microbiol. 2013 Apr;79(8):2713-20. doi: 10.1128/AEM.03462-12. Epub 2013 Feb 15.

26.

Computational modeling and experimental validation of the Legionella and Coxiella virulence-related type-IVB secretion signal.

Lifshitz Z, Burstein D, Peeri M, Zusman T, Schwartz K, Shuman HA, Pupko T, Segal G.

Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):E707-15. doi: 10.1073/pnas.1215278110. Epub 2013 Feb 4.

27.

In vitro derivation of macrophage from guinea pig bone marrow with human M-CSF.

Yu KO, Porcelli SA, Shuman HA.

J Immunol Methods. 2013 Mar 29;389(1-2):88-94. doi: 10.1016/j.jim.2013.01.005. Epub 2013 Jan 16.

PMID:
23333710
28.

Methods to study legionella transcriptome in vitro and in vivo.

Faucher SP, Shuman HA.

Methods Mol Biol. 2013;954:567-82. doi: 10.1007/978-1-62703-161-5_35.

PMID:
23150421
29.

Myosin IC generates power over a range of loads via a new tension-sensing mechanism.

Greenberg MJ, Lin T, Goldman YE, Shuman H, Ostap EM.

Proc Natl Acad Sci U S A. 2012 Sep 11;109(37):E2433-40. doi: 10.1073/pnas.1207811109. Epub 2012 Aug 20.

30.

Resolving two-dimensional kinetics of the integrin αIIbβ3-fibrinogen interactions using binding-unbinding correlation spectroscopy.

Litvinov RI, Mekler A, Shuman H, Bennett JS, Barsegov V, Weisel JW.

J Biol Chem. 2012 Oct 12;287(42):35275-85. doi: 10.1074/jbc.M112.404848. Epub 2012 Aug 14.

31.

Force-dependent detachment of kinesin-2 biases track switching at cytoskeletal filament intersections.

Schroeder HW 3rd, Hendricks AG, Ikeda K, Shuman H, Rodionov V, Ikebe M, Goldman YE, Holzbaur EL.

Biophys J. 2012 Jul 3;103(1):48-58. doi: 10.1016/j.bpj.2012.05.037.

32.

A pathogen's journey in the host cell: Bridges between actin and traffic.

Franco IS, Shuman HA.

Bioarchitecture. 2012 Feb 1;2(2):38-42.

33.

Calcium regulation of myosin-I tension sensing.

Lewis JH, Greenberg MJ, Laakso JM, Shuman H, Ostap EM.

Biophys J. 2012 Jun 20;102(12):2799-807. doi: 10.1016/j.bpj.2012.05.014. Epub 2012 Jun 19.

34.

Kinetic schemes for post-synchronized single molecule dynamics.

Chen C, Greenberg MJ, Laakso JM, Ostap EM, Goldman YE, Shuman H.

Biophys J. 2012 Mar 21;102(6):L23-5. doi: 10.1016/j.bpj.2012.01.054. Epub 2012 Mar 20.

35.

The Legionella pneumophila effector VipA is an actin nucleator that alters host cell organelle trafficking.

Franco IS, Shohdy N, Shuman HA.

PLoS Pathog. 2012 Feb;8(2):e1002546. doi: 10.1371/journal.ppat.1002546. Epub 2012 Feb 23.

36.

Whole-genome sequence of the human pathogen Legionella pneumophila serogroup 12 strain 570-CO-H.

Amaro F, Gilbert JA, Owens S, Trimble W, Shuman HA.

J Bacteriol. 2012 Mar;194(6):1613-4. doi: 10.1128/JB.06626-11.

37.

The overlapping host responses to bacterial cyclic dinucleotides.

Abdul-Sater AA, Grajkowski A, Erdjument-Bromage H, Plumlee C, Levi A, Schreiber MT, Lee C, Shuman H, Beaucage SL, Schindler C.

Microbes Infect. 2012 Feb;14(2):188-97. doi: 10.1016/j.micinf.2011.09.002. Epub 2011 Sep 10.

38.

Small Regulatory RNA and Legionella pneumophila.

Faucher SP, Shuman HA.

Front Microbiol. 2011 May 6;2:98. doi: 10.3389/fmicb.2011.00098. eCollection 2011.

39.

Legionella Pneumophila Transcriptome during Intracellular Multiplication in Human Macrophages.

Faucher SP, Mueller CA, Shuman HA.

Front Microbiol. 2011 Apr 4;2:60. doi: 10.3389/fmicb.2011.00060. eCollection 2011.

40.

Chemical synthesis enables biochemical and antibacterial evaluation of streptolydigin antibiotics.

Pronin SV, Martinez A, Kuznedelov K, Severinov K, Shuman HA, Kozmin SA.

J Am Chem Soc. 2011 Aug 10;133(31):12172-84. doi: 10.1021/ja2041964. Epub 2011 Jul 20.

41.

A novel conserved targeting motif found in ABCA transporters mediates trafficking to early post-Golgi compartments.

Beers MF, Hawkins A, Shuman H, Zhao M, Newitt JL, Maguire JA, Ding W, Mulugeta S.

J Lipid Res. 2011 Aug;52(8):1471-82. doi: 10.1194/jlr.M013284. Epub 2011 May 17.

42.

Cyclic diguanylate signaling proteins control intracellular growth of Legionella pneumophila.

Levi A, Folcher M, Jenal U, Shuman HA.

MBio. 2011 Jan 11;2(1):e00316-10. doi: 10.1128/mBio.00316-10.

43.

Comparison of Brownian-dynamics-based estimates of polymer tension with direct force measurements.

Arsenault ME, Purohit PK, Goldman YE, Shuman H, Bau HH.

Phys Rev E Stat Nonlin Soft Matter Phys. 2010 Nov;82(5 Pt 1):051923. Epub 2010 Nov 17.

44.

Dissociation of bimolecular αIIbβ3-fibrinogen complex under a constant tensile force.

Litvinov RI, Barsegov V, Schissler AJ, Fisher AR, Bennett JS, Weisel JW, Shuman H.

Biophys J. 2011 Jan 5;100(1):165-73. doi: 10.1016/j.bpj.2010.11.019.

45.

A new heterolobosean amoeba Solumitrus palustris n. g., n. sp. isolated from freshwater marsh soil.

Anderson OR, Wang W, Faucher SP, Bi K, Shuman HA.

J Eukaryot Microbiol. 2011 Jan-Feb;58(1):60-7. doi: 10.1111/j.1550-7408.2010.00520.x.

PMID:
21182560
46.

Antibiotics and UV radiation induce competence for natural transformation in Legionella pneumophila.

Charpentier X, Kay E, Schneider D, Shuman HA.

J Bacteriol. 2011 Mar;193(5):1114-21. doi: 10.1128/JB.01146-10. Epub 2010 Dec 17.

47.

Single-molecule adhesion forces and attachment lifetimes of myosin-I phosphoinositide interactions.

Pyrpassopoulos S, Shuman H, Ostap EM.

Biophys J. 2010 Dec 15;99(12):3916-22. doi: 10.1016/j.bpj.2010.10.043.

48.

ArgR-regulated genes are derepressed in the Legionella-containing vacuole.

Hovel-Miner G, Faucher SP, Charpentier X, Shuman HA.

J Bacteriol. 2010 Sep;192(17):4504-16. doi: 10.1128/JB.00465-10. Epub 2010 Jul 9.

49.

Motor number controls cargo switching at actin-microtubule intersections in vitro.

Schroeder HW 3rd, Mitchell C, Shuman H, Holzbaur EL, Goldman YE.

Curr Biol. 2010 Apr 27;20(8):687-96. doi: 10.1016/j.cub.2010.03.024. Epub 2010 Apr 15.

50.

Legionella pneumophila 6S RNA optimizes intracellular multiplication.

Faucher SP, Friedlander G, Livny J, Margalit H, Shuman HA.

Proc Natl Acad Sci U S A. 2010 Apr 20;107(16):7533-8. doi: 10.1073/pnas.0911764107. Epub 2010 Apr 5.

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