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Items: 1 to 50 of 125

1.

Directly visualizing drug-induced arrhythmias with aligned human pluripotent stem cell-based ventricular cardiac anisotropic sheet.

Shum A, Wong AO, Chan CW, Costa KD, Khine M, Kong CW, Li RA.

J Pharmacol Toxicol Methods. 2019 Sep - Oct;99:106595. doi: 10.1016/j.vascn.2019.05.176. Epub 2019 Oct 17. No abstract available.

PMID:
31962922
2.

Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease.

Lalaoui N, Boyden SE, Oda H, Wood GM, Stone DL, Chau D, Liu L, Stoffels M, Kratina T, Lawlor KE, Zaal KJM, Hoffmann PM, Etemadi N, Shield-Artin K, Biben C, Tsai WL, Blake MD, Kuehn HS, Yang D, Anderton H, Silke N, Wachsmuth L, Zheng L, Moura NS, Beck DB, Gutierrez-Cruz G, Ombrello AK, Pinto-Patarroyo GP, Kueh AJ, Herold MJ, Hall C, Wang H, Chae JJ, Dmitrieva NI, McKenzie M, Light A, Barham BK, Jones A, Romeo TM, Zhou Q, Aksentijevich I, Mullikin JC, Gross AJ, Shum AK, Hawkins ED, Masters SL, Lenardo MJ, Boehm M, Rosenzweig SD, Pasparakis M, Voss AK, Gadina M, Kastner DL, Silke J.

Nature. 2020 Jan;577(7788):103-108. doi: 10.1038/s41586-019-1828-5. Epub 2019 Dec 11.

PMID:
31827281
3.

Natural clinical course of progressive supranuclear palsy in Chinese patients in Hong Kong.

Shea YF, Shum ACK, Lee SC, Chiu PKC, Leung KS, Kwan YK, Mok FCK, Chan FHW.

Hong Kong Med J. 2019 Dec 4;25(6). doi: 10.12809/hkmj198101. [Epub ahead of print]

4.

Chinese patients with Lewy body dementia had shorter survival and developed complications earlier than those with Alzheimer's disease.

Shea YF, Lee SC, Shum ACK, Chiu PK, Chu LW, Chan HWF.

Singapore Med J. 2019 Sep 6. doi: 10.11622/smedj.2019103. [Epub ahead of print]

5.

A Community-Based Response to a Suicide Cluster.

Lai CCS, Law YW, Shum AKY, Ip FWL, Yip PSF.

Crisis. 2019 Aug 16:1-9. doi: 10.1027/0227-5910/a000616. [Epub ahead of print]

PMID:
31418310
6.

Highly Sensitive Quantitative Determination of Retinoic Acid Levels, Retinoic Acid Synthesis, and Catabolism in Embryonic Tissue Using a Reporter Cell-Based Method.

Lee LMY, Tam STK, McCaffery PJ, Shum ASW.

Methods Mol Biol. 2019;2019:181-192. doi: 10.1007/978-1-4939-9585-1_13.

PMID:
31359397
7.

A database of amphibian karyotypes.

Perkins RD, Gamboa JR, Jonika MM, Lo J, Shum A, Adams RH, Blackmon H.

Chromosome Res. 2019 Dec;27(4):313-319. doi: 10.1007/s10577-019-09613-1. Epub 2019 Jul 23.

PMID:
31338646
8.

Co-Creation and Impacts of a Suicide Prevention Video.

Cheng Q, Shum AKY, Ip FWL, Wong HK, Yip WKK, Kam AHL, Yip PSF.

Crisis. 2020 Jan;41(1):7-14. doi: 10.1027/0227-5910/a000593. Epub 2019 May 8.

PMID:
31066312
9.

A Digital Game and School-Based Intervention for Students in Hong Kong: Quasi-Experimental Design.

Shum AK, Lai ES, Leung WG, Cheng MN, Wong HK, So SW, Law YW, Yip PS.

J Med Internet Res. 2019 Apr 5;21(4):e12003. doi: 10.2196/12003.

10.

Analysis of pulmonary features and treatment approaches in the COPA syndrome.

Tsui JL, Estrada OA, Deng Z, Wang KM, Law CS, Elicker BM, Jones KD, Dell SD, Gudmundsson G, Hansdottir S, Helfgott SM, Volpi S, Gattorno M, Waterfield MR, Chan AY, Chung SA, Ley B, Shum AK.

ERJ Open Res. 2018 Jun 27;4(2). pii: 00017-2018. doi: 10.1183/23120541.00017-2018. eCollection 2018 Apr.

11.

Proteomic profiling of skeletal and cardiac muscle in cancer cachexia: alterations in sarcomeric and mitochondrial protein expression.

Shum AMY, Poljak A, Bentley NL, Turner N, Tan TC, Polly P.

Oncotarget. 2018 Apr 24;9(31):22001-22022. doi: 10.18632/oncotarget.25146. eCollection 2018 Apr 24.

12.

Probing flecainide block of INa using human pluripotent stem cell-derived ventricular cardiomyocytes adapted to automated patch-clamping and 2D monolayers.

Geng L, Kong CW, Wong AOT, Shum AM, Chow MZY, Che H, Zhang C, Yau KL, Chan CW, Keung W, Li RA.

Toxicol Lett. 2018 Sep 15;294:61-72. doi: 10.1016/j.toxlet.2018.05.006. Epub 2018 May 21.

PMID:
29758359
13.

Type I interferon pathway activation in COPA syndrome.

Volpi S, Tsui J, Mariani M, Pastorino C, Caorsi R, Sacco O, Ravelli A, Shum AK, Gattorno M, Picco P.

Clin Immunol. 2018 Feb;187:33-36. doi: 10.1016/j.clim.2017.10.001. Epub 2017 Oct 10.

PMID:
29030294
14.

Microfluidic Imaging Flow Cytometry by Asymmetric-detection Time-stretch Optical Microscopy (ATOM).

Tang AHL, Lai QTK, Chung BMF, Lee KCM, Mok ATY, Yip GK, Shum AHC, Wong KKY, Tsia KK.

J Vis Exp. 2017 Jun 28;(124). doi: 10.3791/55840.

15.

Epidemiology of Dizzy Patient Population in a Neurotology Clinic and Predictors of Peripheral Etiology.

Muelleman T, Shew M, Subbarayan R, Shum A, Sykes K, Staecker H, Lin J.

Otol Neurotol. 2017 Jul;38(6):870-875. doi: 10.1097/MAO.0000000000001429.

PMID:
28498271
16.

Perturbation of Retinoid Homeostasis Increases Malformation Risk in Embryos Exposed to Pregestational Diabetes.

Lee LM, Leung MB, Kwok RC, Leung YC, Wang CC, McCaffery PJ, Copp AJ, Shum AS.

Diabetes. 2017 Apr;66(4):1041-1051. doi: 10.2337/db15-1570. Epub 2017 Jan 13.

17.

Increasing the physical size and nucleation status of human pluripotent stem cell-derived ventricular cardiomyocytes by cell fusion.

Kong CW, Chen S, Geng L, Shum AM, Sun D, Li RA.

Stem Cell Res. 2017 Mar;19:76-81. doi: 10.1016/j.scr.2017.01.003. Epub 2017 Jan 6.

18.

A Micropatterned Human Pluripotent Stem Cell-Based Ventricular Cardiac Anisotropic Sheet for Visualizing Drug-Induced Arrhythmogenicity.

Shum AM, Che H, Wong AO, Zhang C, Wu H, Chan CW, Costa K, Khine M, Kong CW, Li RA.

Adv Mater. 2017 Jan;29(1). doi: 10.1002/adma.201602448. Epub 2016 Nov 2.

PMID:
27805726
19.

Evaluation of a Digital Game-Based Learning Program for Enhancing Youth Mental Health: A Structural Equation Modeling of the Program Effectiveness.

Huen JM, Lai ES, Shum AK, So SW, Chan MK, Wong PW, Law YW, Yip PS.

JMIR Ment Health. 2016 Oct 7;3(4):e46.

20.

Ganglioside GM3 synthase depletion reverses neuropathic pain and small fiber neuropathy in diet-induced diabetic mice.

Menichella DM, Jayaraj ND, Wilson HM, Ren D, Flood K, Wang XQ, Shum A, Miller RJ, Paller AS.

Mol Pain. 2016 Sep 2;12. pii: 1744806916666284. doi: 10.1177/1744806916666284. Print 2016.

21.

Discovery and characterization of novel small-molecule CXCR4 receptor agonists and antagonists.

Mishra RK, Shum AK, Platanias LC, Miller RJ, Schiltz GE.

Sci Rep. 2016 Jul 26;6:30155. doi: 10.1038/srep30155.

22.

Rare variants, autoimmune disease, and arthritis.

Chung SA, Shum AK.

Curr Opin Rheumatol. 2016 Jul;28(4):346-51. doi: 10.1097/BOR.0000000000000298. Review.

23.

Securement of the indwelling urinary catheter for adult patients: a best practice implementation.

Shum A, Wong KS, Sankaran K, Goh ML.

Int J Evid Based Healthc. 2017 Mar;15(1):3-12. doi: 10.1097/XEB.0000000000000084.

PMID:
27164317
24.

Regulation of neurogenesis by calcium signaling.

Toth AB, Shum AK, Prakriya M.

Cell Calcium. 2016 Mar;59(2-3):124-34. doi: 10.1016/j.ceca.2016.02.011. Epub 2016 Mar 15. Review.

25.

Adverse reproductive effects of maternal low-dose melamine exposure during pregnancy in rats.

Chu CY, Tang LY, Li L, Shum AS, Fung KP, Wang CC.

Environ Toxicol. 2017 Jan;32(1):131-138. doi: 10.1002/tox.22218. Epub 2015 Nov 21.

PMID:
26589250
26.

Cardiac and skeletal muscles show molecularly distinct responses to cancer cachexia.

Shum AM, Fung DC, Corley SM, McGill MC, Bentley NL, Tan TC, Wilkins MR, Polly P.

Physiol Genomics. 2015 Dec;47(12):588-99. doi: 10.1152/physiolgenomics.00128.2014. Epub 2015 Sep 22.

PMID:
26395599
27.

Survival in interstitial pneumonia with features of autoimmune disease: a comparison of proposed criteria.

Assayag D, Kim EJ, Elicker BM, Jones KD, Golden JA, King TE Jr, Koth LL, Shum AK, Wolters PJ, Collard HR, Lee JS.

Respir Med. 2015 Oct;109(10):1326-31. doi: 10.1016/j.rmed.2015.08.010. Epub 2015 Aug 15.

28.

Hair cell counts in a rat model of sound damage: Effects of tissue preparation & identification of regions of hair cell loss.

Neal C, Kennon-McGill S, Freemyer A, Shum A, Staecker H, Durham D.

Hear Res. 2015 Oct;328:120-32. doi: 10.1016/j.heares.2015.08.008. Epub 2015 Aug 20.

29.

T cell types that take your breath away.

Shum AK.

Sci Transl Med. 2015 Aug 19;7(301):301fs33. doi: 10.1126/scitranslmed.aac9737.

PMID:
26290409
30.

The effect of bronchodilators on forced vital capacity measurement in patients with idiopathic pulmonary fibrosis.

Assayag D, Vittinghoff E, Ryerson CJ, Cocconcelli E, Tonelli R, Hu X, Elicker BM, Golden JA, Jones KD, King TE Jr, Koth LL, Lee JS, Ley B, Shum AK, Wolters PJ, Ryu JH, Collard HR.

Respir Med. 2015 Aug;109(8):1058-62. doi: 10.1016/j.rmed.2015.06.012. Epub 2015 Jun 24.

31.

Transglutaminase 4 as a prostate autoantigen in male subfertility.

Landegren N, Sharon D, Shum AK, Khan IS, Fasano KJ, Hallgren Å, Kampf C, Freyhult E, Ardesjö-Lundgren B, Alimohammadi M, Rathsman S, Ludvigsson JF, Lundh D, Motrich R, Rivero V, Fong L, Giwercman A, Gustafsson J, Perheentupa J, Husebye ES, Anderson MS, Snyder M, Kämpe O.

Sci Transl Med. 2015 Jun 17;7(292):292ra101. doi: 10.1126/scitranslmed.aaa9186.

PMID:
26084804
32.

COPA mutations impair ER-Golgi transport and cause hereditary autoimmune-mediated lung disease and arthritis.

Watkin LB, Jessen B, Wiszniewski W, Vece TJ, Jan M, Sha Y, Thamsen M, Santos-Cortez RL, Lee K, Gambin T, Forbes LR, Law CS, Stray-Pedersen A, Cheng MH, Mace EM, Anderson MS, Liu D, Tang LF, Nicholas SK, Nahmod K, Makedonas G, Canter DL, Kwok PY, Hicks J, Jones KD, Penney S, Jhangiani SN, Rosenblum MD, Dell SD, Waterfield MR, Papa FR, Muzny DM, Zaitlen N, Leal SM, Gonzaga-Jauregui C; Baylor-Hopkins Center for Mendelian Genomics, Boerwinkle E, Eissa NT, Gibbs RA, Lupski JR, Orange JS, Shum AK.

Nat Genet. 2015 Jun;47(6):654-60. doi: 10.1038/ng.3279. Epub 2015 Apr 20.

33.

The role of pre-existing cross-reactive antibodies in determining the efficacy of vaccination in humans: study protocol for a randomized controlled trial.

Low JG, Wijaya L, Li GK, Lim EY, Shum AK, Cheung YB, Ooi EE.

Trials. 2015 Apr 10;16:147. doi: 10.1186/s13063-015-0651-z.

34.
35.

Retired reps can do bank work and then regain accreditation.

Shum A.

Nurs Stand. 2014 Dec 31;29(16):33. doi: 10.7748/ns.29.16.33.s42. No abstract available.

PMID:
25515481
36.

Store-operated CRAC channels regulate gene expression and proliferation in neural progenitor cells.

Somasundaram A, Shum AK, McBride HJ, Kessler JA, Feske S, Miller RJ, Prakriya M.

J Neurosci. 2014 Jul 2;34(27):9107-23. doi: 10.1523/JNEUROSCI.0263-14.2014.

37.

CXCR4 chemokine receptor signaling mediates pain in diabetic neuropathy.

Menichella DM, Abdelhak B, Ren D, Shum A, Frietag C, Miller RJ.

Mol Pain. 2014 Jun 25;10:42. doi: 10.1186/1744-8069-10-42.

38.

Pharmacy students' use of and beliefs about traditional healthcare.

Anwar M, Norris P, Green J, Au S, Li G, Ma M, Prentice R, Shum A, Siaw LA, Yoo S, Zhang S.

J Immigr Minor Health. 2015 Jun;17(3):895-904. doi: 10.1007/s10903-014-0013-z.

PMID:
24711106
39.

The effects of sedative music on sleep quality of older community-dwelling adults in Singapore.

Shum A, Taylor BJ, Thayala J, Chan MF.

Complement Ther Med. 2014 Feb;22(1):49-56. doi: 10.1016/j.ctim.2013.11.003. Epub 2013 Nov 14.

PMID:
24559816
40.

Melamine toxicity in rat foetuses and infants.

Wang CC, Fung KP, Fok TF, Lau TK, Pang CP, Chu KO, Shum AS, Lam CW, Chan MH, Ho CS, Lau CM, Ting TL, Mak TC.

Hong Kong Med J. 2013 Dec;19 Suppl 8:20-2. No abstract available.

41.

Protein microarray analysis reveals BAFF-binding autoantibodies in systemic lupus erythematosus.

Price JV, Haddon DJ, Kemmer D, Delepine G, Mandelbaum G, Jarrell JA, Gupta R, Balboni I, Chakravarty EF, Sokolove J, Shum AK, Anderson MS, Cheng MH, Robinson WH, Browne SK, Holland SM, Baechler EC, Utz PJ.

J Clin Invest. 2013 Dec;123(12):5135-45. doi: 10.1172/JCI70231. Epub 2013 Nov 25.

42.

BPIFB1 is a lung-specific autoantigen associated with interstitial lung disease.

Shum AK, Alimohammadi M, Tan CL, Cheng MH, Metzger TC, Law CS, Lwin W, Perheentupa J, Bour-Jordan H, Carel JC, Husebye ES, De Luca F, Janson C, Sargur R, Dubois N, Kajosaari M, Wolters PJ, Chapman HA, Kämpe O, Anderson MS.

Sci Transl Med. 2013 Oct 9;5(206):206ra139. doi: 10.1126/scitranslmed.3006998.

43.

Prevalence and clinical significance of circulating autoantibodies in idiopathic pulmonary fibrosis.

Lee JS, Kim EJ, Lynch KL, Elicker B, Ryerson CJ, Katsumoto TR, Shum AK, Wolters PJ, Cerri S, Richeldi L, Jones KD, King TE Jr, Collard HR.

Respir Med. 2013 Feb;107(2):249-55. doi: 10.1016/j.rmed.2012.10.018. Epub 2012 Nov 24.

44.

A paradoxical teratogenic mechanism for retinoic acid.

Lee LM, Leung CY, Tang WW, Choi HL, Leung YC, McCaffery PJ, Wang CC, Woolf AS, Shum AS.

Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):13668-73. doi: 10.1073/pnas.1200872109. Epub 2012 Aug 6.

45.

Defective autoimmune regulator-dependent central tolerance to myelin protein zero is linked to autoimmune peripheral neuropathy.

Su MA, Davini D, Cheng P, Giang K, Fan U, DeVoss JJ, Johannes KP, Taylor L, Shum AK, Valenzise M, Meloni A, Bour-Jordan H, Anderson MS.

J Immunol. 2012 May 15;188(10):4906-12. doi: 10.4049/jimmunol.1200493. Epub 2012 Apr 6.

46.

Cancer cachexia: molecular targets and pathways for diagnosis and drug intervention.

Shum AM, Polly P.

Endocr Metab Immune Disord Drug Targets. 2012 Sep;12(3):247-59. Review.

PMID:
22385113
47.

Disruption of MEF2C signaling and loss of sarcomeric and mitochondrial integrity in cancer-induced skeletal muscle wasting.

Shum AM, Mahendradatta T, Taylor RJ, Painter AB, Moore MM, Tsoli M, Tan TC, Clarke SJ, Robertson GR, Polly P.

Aging (Albany NY). 2012 Feb;4(2):133-43.

48.

A contact lens with embedded sensor for monitoring tear glucose level.

Yao H, Shum AJ, Cowan M, Lähdesmäki I, Parviz BA.

Biosens Bioelectron. 2011 Mar 15;26(7):3290-6. doi: 10.1016/j.bios.2010.12.042. Epub 2010 Dec 31.

49.

Lack of motor neuron differentiation is an intrinsic property of the mouse secondary neural tube.

Shum AS, Tang LS, Copp AJ, Roelink H.

Dev Dyn. 2010 Dec;239(12):3192-203. doi: 10.1002/dvdy.22457. Epub 2010 Oct 19.

50.

Inertially assisted nanoscale self-assembly.

Saeedi E, Marcheselli C, Shum A, Parviz BA.

Nanotechnology. 2010 Sep 17;21(37):375604. doi: 10.1088/0957-4484/21/37/375604. Epub 2010 Aug 19.

PMID:
20720294

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