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Items: 1 to 20 of 30


Syk degradation restrains plasma cell formation and promotes zonal transitions in germinal centers.

Davidzohn N, Biram A, Stoler-Barak L, Grenov A, Dassa B, Shulman Z.

J Exp Med. 2020 Mar 2;217(3). pii: e20191043. doi: 10.1084/jem.20191043.


B cell dissemination patterns during the germinal center reaction revealed by whole-organ imaging.

Stoler-Barak L, Biram A, Davidzohn N, Addadi Y, Golani O, Shulman Z.

J Exp Med. 2019 Nov 4;216(11):2515-2530. doi: 10.1084/jem.20190789. Epub 2019 Sep 6.


Stable contacts of naïve CD4 T cells with migratory dendritic cells are ICAM-1-dependent but dispensable for proliferation in vivo.

Kozlovski S, Atrakchi O, Feigelson SW, Shulman Z, Alon R.

Cell Adh Migr. 2019 Dec;13(1):315-321. doi: 10.1080/19336918.2019.1644857.


Activated Peyer's patch B cells sample antigen directly from M cells in the subepithelial dome.

Komban RJ, Strömberg A, Biram A, Cervin J, Lebrero-Fernández C, Mabbott N, Yrlid U, Shulman Z, Bemark M, Lycke N.

Nat Commun. 2019 Jun 3;10(1):2423. doi: 10.1038/s41467-019-10144-w.


T cell interactions with B cells during germinal center formation, a three-step model.

Biram A, Davidzohn N, Shulman Z.

Immunol Rev. 2019 Mar;288(1):37-48. doi: 10.1111/imr.12737. Review.


BCR affinity differentially regulates colonization of the subepithelial dome and infiltration into germinal centers within Peyer's patches.

Biram A, Strömberg A, Winter E, Stoler-Barak L, Salomon R, Addadi Y, Dahan R, Yaari G, Bemark M, Shulman Z.

Nat Immunol. 2019 Apr;20(4):482-492. doi: 10.1038/s41590-019-0325-1. Epub 2019 Mar 4.


Covalent Docking Identifies a Potent and Selective MKK7 Inhibitor.

Shraga A, Olshvang E, Davidzohn N, Khoshkenar P, Germain N, Shurrush K, Carvalho S, Avram L, Albeck S, Unger T, Lefker B, Subramanyam C, Hudkins RL, Mitchell A, Shulman Z, Kinoshita T, London N.

Cell Chem Biol. 2019 Jan 17;26(1):98-108.e5. doi: 10.1016/j.chembiol.2018.10.011. Epub 2018 Nov 15.


Breast Implant Mycobacterial Infections: An Epidemiologic Review and Outcome Analysis.

Al-Halabi B, Viezel-Mathieu A, Shulman Z, Behr MA, Fouda Neel O.

Plast Reconstr Surg. 2018 Nov;142(5):639e-652e. doi: 10.1097/PRS.0000000000004892.


ICAMs Are Not Obligatory for Functional Immune Synapses between Naive CD4 T Cells and Lymph Node DCs.

Feigelson SW, Solomon A, Biram A, Hatzav M, Lichtenstein M, Regev O, Kozlovski S, Varol D, Curato C, Leshkowitz D, Jung S, Shulman Z, Alon R.

Cell Rep. 2018 Jan 23;22(4):849-859. doi: 10.1016/j.celrep.2017.12.103. Epub 2018 Jan 28.


Spatial reconstruction of immune niches by combining photoactivatable reporters and scRNA-seq.

Medaglia C, Giladi A, Stoler-Barak L, De Giovanni M, Salame TM, Biram A, David E, Li H, Iannacone M, Shulman Z, Amit I.

Science. 2017 Dec 22;358(6370):1622-1626. doi: 10.1126/science.aao4277. Epub 2017 Dec 7.


ICAMs support B cell interactions with T follicular helper cells and promote clonal selection.

Zaretsky I, Atrakchi O, Mazor RD, Stoler-Barak L, Biram A, Feigelson SW, Gitlin AD, Engelhardt B, Shulman Z.

J Exp Med. 2017 Nov 6;214(11):3435-3448. doi: 10.1084/jem.20171129. Epub 2017 Sep 22.


Independent Roles of Switching and Hypermutation in the Development and Persistence of B Lymphocyte Memory.

Gitlin AD, von Boehmer L, Gazumyan A, Shulman Z, Oliveira TY, Nussenzweig MC.

Immunity. 2016 Apr 19;44(4):769-81. doi: 10.1016/j.immuni.2016.01.011. Epub 2016 Mar 2.


HUMORAL IMMUNITY. T cell help controls the speed of the cell cycle in germinal center B cells.

Gitlin AD, Mayer CT, Oliveira TY, Shulman Z, Jones MJ, Koren A, Nussenzweig MC.

Science. 2015 Aug 7;349(6248):643-6. doi: 10.1126/science.aac4919. Epub 2015 Jul 16.


Synaptojanin 2 is a druggable mediator of metastasis and the gene is overexpressed and amplified in breast cancer.

Ben-Chetrit N, Chetrit D, Russell R, Körner C, Mancini M, Abdul-Hai A, Itkin T, Carvalho S, Cohen-Dvashi H, Koestler WJ, Shukla K, Lindzen M, Kedmi M, Lauriola M, Shulman Z, Barr H, Seger D, Ferraro DA, Pareja F, Gil-Henn H, Lapidot T, Alon R, Milanezi F, Symons M, Ben-Hamo R, Efroni S, Schmitt F, Wiemann S, Caldas C, Ehrlich M, Yarden Y.

Sci Signal. 2015 Jan 20;8(360):ra7. doi: 10.1126/scisignal.2005537.


Dynamic signaling by T follicular helper cells during germinal center B cell selection.

Shulman Z, Gitlin AD, Weinstein JS, Lainez B, Esplugues E, Flavell RA, Craft JE, Nussenzweig MC.

Science. 2014 Aug 29;345(6200):1058-62. doi: 10.1126/science.1257861.


Clonal selection in the germinal centre by regulated proliferation and hypermutation.

Gitlin AD, Shulman Z, Nussenzweig MC.

Nature. 2014 May 29;509(7502):637-40. doi: 10.1038/nature13300. Epub 2014 May 4.


T follicular helper cell dynamics in germinal centers.

Shulman Z, Gitlin AD, Targ S, Jankovic M, Pasqual G, Nussenzweig MC, Victora GD.

Science. 2013 Aug 9;341(6146):673-7. doi: 10.1126/science.1241680. Epub 2013 Jul 25.


Transendothelial migration of lymphocytes mediated by intraendothelial vesicle stores rather than by extracellular chemokine depots.

Shulman Z, Cohen SJ, Roediger B, Kalchenko V, Jain R, Grabovsky V, Klein E, Shinder V, Stoler-Barak L, Feigelson SW, Meshel T, Nurmi SM, Goldstein I, Hartley O, Gahmberg CG, Etzioni A, Weninger W, Ben-Baruch A, Alon R.

Nat Immunol. 2011 Dec 4;13(1):67-76. doi: 10.1038/ni.2173.


Real-time analysis of integrin-dependent transendothelial migration and integrin-independent interstitial motility of leukocytes.

Shulman Z, Alon R.

Methods Mol Biol. 2012;757:31-45. doi: 10.1007/978-1-61779-166-6_3.


Kindlin-3 is required for the stabilization of TCR-stimulated LFA-1:ICAM-1 bonds critical for lymphocyte arrest and spreading on dendritic cells.

Feigelson SW, Grabovsky V, Manevich-Mendelson E, Pasvolsky R, Shulman Z, Shinder V, Klein E, Etzioni A, Aker M, Alon R.

Blood. 2011 Jun 30;117(26):7042-52. doi: 10.1182/blood-2010-12-322859. Epub 2011 May 2.


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