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Variability in alkaloid and phenolic content vis-a-vis antigout potential among the natural population of Gloriosa superba (L.) collected from Central India.

Misra A, Srivastava S, Shukla PK, Kumar M, Khalid M, Kushwaha P, Agrawal PK.

Nat Prod Res. 2019 Oct 14:1-5. doi: 10.1080/14786419.2019.1675069. [Epub ahead of print]


Quinazoline based 1,3,5-triazine derivatives as cancer inhibitors by impeding the phosphorylated RET tyrosine kinase pathway: Design, synthesis, docking, and QSAR study.

Pathak P, Naumovich V, Grishina M, Shukla PK, Verma A, Potemkin V.

Arch Pharm (Weinheim). 2019 Sep;352(9):e1900053. doi: 10.1002/ardp.201900053. Epub 2019 Aug 5.


Biochemical regulation and structural analysis of copper-transporting ATPase in a human hepatoma cell line for Wilson disease.

Agnihotry S, Dhusia K, Srivastav AK, Upadhyay J, Verma V, Shukla PK, Ramteke PW, Gautam B.

J Cell Biochem. 2019 Nov;120(11):18826-18844. doi: 10.1002/jcb.29199. Epub 2019 Jul 9.


Fast and Secure Medical Image Encryption Based on Non Linear 4D Logistic Map and DNA Sequences (NL4DLM_DNA).

Stalin S, Maheshwary P, Shukla PK, Maheshwari M, Gour B, Khare A.

J Med Syst. 2019 Jul 4;43(8):267. doi: 10.1007/s10916-019-1389-z.


Postoperative Imaging After Lobectomy: Predicting the Displacement and Change in Orientation of Nonresected Lung Nodules.

Digumarthy SR, Shukla PK, Mendoza DP, Guo L, Chretien YR, Shepard JO, Kalra MK.

J Comput Assist Tomogr. 2019 Jul/Aug;43(4):592-598. doi: 10.1097/RCT.0000000000000871.


Plasma exosomes exacerbate alcohol- and acetaminophen-induced toxicity via CYP2E1 pathway.

Rahman MA, Kodidela S, Sinha N, Haque S, Shukla PK, Rao R, Kumar S.

Sci Rep. 2019 Apr 25;9(1):6571. doi: 10.1038/s41598-019-43064-2.


Exploration of some new secretory proteins to be employed for companion diagnosis of Mycobacterium tuberculosis.

Tripathi DK, Srivastava K, Nagpal KL, Shukla PK, Srivastava KK.

Immunol Lett. 2019 May;209:67-74. doi: 10.1016/j.imlet.2019.03.010. Epub 2019 Mar 18.


A novel monoclonal antibody against enolase antigen of Aspergillus fumigatus protects experimental aspergillosis in mice.

Yadav RK, Shukla PK.

FEMS Microbiol Lett. 2019 Feb 1;366(3). pii: fnz015. doi: 10.1093/femsle/fnz015.


Optical study of stress hormone-induced nanoscale structural alteration in brain using partial wave spectroscopic microscopy.

Bhandari S, Shukla PK, Almabadi HM, Sahay P, Rao R, Pradhan P.

J Biophotonics. 2019 Jun;12(6):e201800002. doi: 10.1002/jbio.201800002. Epub 2019 Mar 21.


EGF receptor plays a role in the mechanism of glutamine-mediated prevention of alcohol-induced gut barrier dysfunction and liver injury.

Meena AS, Shukla PK, Sheth P, Rao R.

J Nutr Biochem. 2019 Feb;64:128-143. doi: 10.1016/j.jnutbio.2018.10.016. Epub 2018 Nov 6.


Human Defensin-5 Blocks Ethanol and Colitis-Induced Dysbiosis, Tight Junction Disruption and Inflammation in Mouse Intestine.

Shukla PK, Meena AS, Rao V, Rao RG, Balazs L, Rao R.

Sci Rep. 2018 Nov 2;8(1):16241. doi: 10.1038/s41598-018-34263-4.


Deletion of TLR-4 attenuates fetal alcohol exposure-induced gene expression and social interaction deficits.

Shukla PK, Meena AS, Rao R, Rao R.

Alcohol. 2018 Dec;73:73-78. doi: 10.1016/j.alcohol.2018.04.004. Epub 2018 Apr 18.


Prevention and treatment of secretory diarrhea by the lysophosphatidic acid analog Rx100.

Thompson KE, Ray RM, Alli S, Ge W, Boler A, Shannon McCool W, Meena AS, Shukla PK, Rao R, Johnson LR, Miller MA, Tigyi GJ.

Exp Biol Med (Maywood). 2018 Sep;243(13):1056-1065. doi: 10.1177/1535370218803349. Epub 2018 Sep 25.


Response Surface Methodology-Genetic Algorithm Based Medium Optimization, Purification, and Characterization of Cholesterol Oxidase from Streptomyces rimosus.

Srivastava A, Singh V, Haque S, Pandey S, Mishra M, Jawed A, Shukla PK, Singh PK, Tripathi CKM.

Sci Rep. 2018 Jul 19;8(1):10913. doi: 10.1038/s41598-018-29241-9.


Leishmania donovani molecules recognized by sera of filaria infected host facilitate filarial infection.

Verma R, Kushwaha V, Pandey S, Thota JR, Vishwakarma P, Parmar N, Yadav PK, Tewari P, Kar S, Shukla PK, Murthy PK.

Parasitol Res. 2018 Sep;117(9):2901-2912. doi: 10.1007/s00436-018-5981-9. Epub 2018 Jun 26.


Lactobacillus plantarum prevents and mitigates alcohol-induced disruption of colonic epithelial tight junctions, endotoxemia, and liver damage by an EGF receptor-dependent mechanism.

Shukla PK, Meena AS, Manda B, Gomes-Solecki M, Dietrich P, Dragatsis I, Rao R.

FASEB J. 2018 Jun 18:fj201800351R. doi: 10.1096/fj.201800351R. [Epub ahead of print]


Effect of Azolla feeding on the growth, feed conversion ratio, blood biochemical attributes and immune competence traits of growing turkeys.

Shukla M, Bhattacharyya A, Shukla PK, Roy D, Yadav B, Sirohi R.

Vet World. 2018 Apr;11(4):459-463. doi: 10.14202/vetworld.2018.459-463. Epub 2018 Apr 11.


Quinazoline clubbed 1,3,5-triazine derivatives as VEGFR2 kinase inhibitors: design, synthesis, docking, in vitro cytotoxicity and in ovo antiangiogenic activity.

Pathak P, Shukla PK, Kumar V, Kumar A, Verma A.

Inflammopharmacology. 2018 Dec;26(6):1441-1453. doi: 10.1007/s10787-018-0471-3. Epub 2018 Apr 16.


Using the Modified Clavien Grading System to Classify Complications of Percutaneous Nephrolithotomy.

Singh AK, Shukla PK, Khan SW, Rathee VS, Dwivedi US, Trivedi S.

Curr Urol. 2018 Feb;11(2):79-84. doi: 10.1159/000447198. Epub 2017 Dec 30.


Phosphorylation hotspot in the C-terminal domain of occludin regulates the dynamics of epithelial junctional complexes.

Manda B, Mir H, Gangwar R, Meena AS, Amin S, Shukla PK, Dalal K, Suzuki T, Rao R.

J Cell Sci. 2018 Apr 6;131(7). pii: jcs206789. doi: 10.1242/jcs.206789.


Simultaneous Quantification of Forskolin and Iso-Forskolin in Coleus forskohlii (Wild.) Briq. and Identification of Elite Chemotype, Collected from Eastern Ghats (India).

Shukla PK, Misra A, Kumar M, Jaichand, Singh K, Akhtar J, Srivastava S, Agrawal PK, Singh Rawat AK.

Pharmacogn Mag. 2018 Jan;13(Suppl 4):S881-S885. doi: 10.4103/pm.pm_202_17. Epub 2018 Jan 31.


Effect of dietary supplementation of sea buckthorn and giloe leaf meal on the body weight gain, feed conversion ratio, biochemical attributes, and meat composition of turkey poults.

Sharma A, Shukla PK, Bhattacharyya A, Kumar U, Roy D, Yadav B, Prakash A.

Vet World. 2018 Jan;11(1):93-98. doi: 10.14202/vetworld.2018.93-98.


Does 8-Nitroguanine Form 8-Oxoguanine? An Insight from Its Reaction with OH Radical.

Bhattacharjee K, Shukla PK.

J Phys Chem B. 2018 Feb 15;122(6):1852-1861. doi: 10.1021/acs.jpcb.7b12192. Epub 2018 Feb 2.


Humid thermal ratio as a tool to assess mango thrips dynamics under subtropical climatic condition.

Gundappa S, Adak T, Shukla PK.

J Environ Biol. 2016 Nov;37(6):1239-45.


Substituted carbamothioic amine-1-carbothioic thioanhydrides as novel trichomonicidal fungicides: Design, synthesis, and biology.

Mandalapu D, Kushwaha B, Gupta S, Krishna S, Srivastava N, Shukla M, Singh P, Chauhan BS, Goyani R, Maikhuri JP, Sashidhara KV, Kumar B, Tripathi R, Shukla PK, Siddiqi MI, Lal J, Gupta G, Sharma VL.

Eur J Med Chem. 2018 Jan 1;143:632-645. doi: 10.1016/j.ejmech.2017.11.060. Epub 2017 Nov 23.


High-performance Thin-layer Chromatographic-densitometric Quantification and Recovery of Bioactive Compounds for Identification of Elite Chemotypes of Gloriosa superba L. Collected from Sikkim Himalayas (India).

Misra A, Shukla PK, Kumar B, Chand J, Kushwaha P, Khalid M, Singh Rawat AK, Srivastava S.

Pharmacogn Mag. 2017 Oct;13(Suppl 3):S700-S705. doi: 10.4103/pm.pm_576_16. Epub 2017 Oct 11.


Gaussian Elimination-Based Novel Canonical Correlation Analysis Method for EEG Motion Artifact Removal.

Roy V, Shukla S, Shukla PK, Rawat P.

J Healthc Eng. 2017;2017:9674712. doi: 10.1155/2017/9674712. Epub 2017 Oct 8.


Identification of GXXXXG motif in Chrysophsin-1 and its implication in the design of analogs with cell-selective antimicrobial and anti-endotoxin activities.

Tripathi AK, Kumari T, Harioudh MK, Yadav PK, Kathuria M, Shukla PK, Mitra K, Ghosh JK.

Sci Rep. 2017 Jun 13;7(1):3384. doi: 10.1038/s41598-017-03576-1.


Selective phenylalanine to proline substitution for improved antimicrobial and anticancer activities of peptides designed on phenylalanine heptad repeat.

Tripathi AK, Kumari T, Tandon A, Sayeed M, Afshan T, Kathuria M, Shukla PK, Mitra K, Ghosh JK.

Acta Biomater. 2017 Jul 15;57:170-186. doi: 10.1016/j.actbio.2017.05.007. Epub 2017 May 5.


Physiological performance of two contrasting rice varieties under water stress.

Khan F, Upreti P, Singh R, Shukla PK, Shirke PA.

Physiol Mol Biol Plants. 2017 Jan;23(1):85-97. doi: 10.1007/s12298-016-0399-2. Epub 2016 Dec 5.


Quantitative analysis of nanoscale intranuclear structural alterations in hippocampal cells in chronic alcoholism via transmission electron microscopy imaging.

Sahay P, Shukla PK, Ghimire HM, Almabadi HM, Tripathi V, Mohanty SK, Rao R, Pradhan P.

Phys Biol. 2017 Mar 1;14(2):026001. doi: 10.1088/1478-3975/aa5d71.


Broad spectrum anti-infective properties of benzisothiazolones and the parallels in their anti-bacterial and anti-fungal effects.

Gopinath P, Yadav RK, Shukla PK, Srivastava K, Puri SK, Muraleedharan KM.

Bioorg Med Chem Lett. 2017 Mar 1;27(5):1291-1295. doi: 10.1016/j.bmcl.2017.01.027. Epub 2017 Jan 12.


Calcium-mediated oxidative stress: a common mechanism in tight junction disruption by different types of cellular stress.

Gangwar R, Meena AS, Shukla PK, Nagaraja AS, Dorniak PL, Pallikuth S, Waters CM, Sood A, Rao R.

Biochem J. 2017 Feb 20;474(5):731-749. doi: 10.1042/BCJ20160679.


Piscidin-1-analogs with double L- and D-lysine residues exhibited different conformations in lipopolysaccharide but comparable anti-endotoxin activities.

Kumar A, Mahajan M, Awasthi B, Tandon A, Harioudh MK, Shree S, Singh P, Shukla PK, Ramachandran R, Mitra K, Bhattacharjya S, Ghosh JK.

Sci Rep. 2017 Jan 4;7:39925. doi: 10.1038/srep39925.


Calcium Channels and Oxidative Stress Mediate a Synergistic Disruption of Tight Junctions by Ethanol and Acetaldehyde in Caco-2 Cell Monolayers.

Samak G, Gangwar R, Meena AS, Rao RG, Shukla PK, Manda B, Narayanan D, Jaggar JH, Rao R.

Sci Rep. 2016 Dec 13;6:38899. doi: 10.1038/srep38899.


Role of N-terminal region of Escherichia coli maltodextrin glucosidase in folding and function of the protein.

Pastor A, Singh AK, Shukla PK, Equbal MJ, Malik ST, Singh TP, Chaudhuri TK.

Biochim Biophys Acta. 2016 Sep;1864(9):1138-1151. doi: 10.1016/j.bbapap.2016.06.008. Epub 2016 Jun 16.


Dual functioning microspheres embedded crosslinked gelatin cryogels for therapeutic intervention in osteomyelitis and associated bone loss.

Pandey G, Mittapelly N, Pant A, Sharma S, Singh P, Banala VT, Trivedi R, Shukla PK, Mishra PR.

Eur J Pharm Sci. 2016 Aug 25;91:105-13. doi: 10.1016/j.ejps.2016.06.008. Epub 2016 Jun 7.


Role of disulfide linkage in action of bis(dialkylaminethiocarbonyl)disulfides as potent double-Edged microbicidal spermicide: Design, synthesis and biology.

Lal N, Jangir S, Bala V, Mandalapu D, Sarswat A, Kumar L, Jain A, Kumar L, Kushwaha B, Pandey AK, Krishna S, Rawat T, Shukla PK, Maikhuri JP, Siddiqi MI, Gupta G, Sharma VL.

Eur J Med Chem. 2016 Jun 10;115:275-90. doi: 10.1016/j.ejmech.2016.03.012. Epub 2016 Mar 9.


Chronic ethanol feeding promotes azoxymethane and dextran sulfate sodium-induced colonic tumorigenesis potentially by enhancing mucosal inflammation.

Shukla PK, Chaudhry KK, Mir H, Gangwar R, Yadav N, Manda B, Meena AS, Rao R.

BMC Cancer. 2016 Mar 7;16:189. doi: 10.1186/s12885-016-2180-x.


Rapid disruption of intestinal epithelial tight junction and barrier dysfunction by ionizing radiation in mouse colon in vivo: protection by N-acetyl-l-cysteine.

Shukla PK, Gangwar R, Manda B, Meena AS, Yadav N, Szabo E, Balogh A, Lee SC, Tigyi G, Rao R.

Am J Physiol Gastrointest Liver Physiol. 2016 May 1;310(9):G705-15. doi: 10.1152/ajpgi.00314.2015. Epub 2016 Jan 28.


Occludin deficiency promotes ethanol-induced disruption of colonic epithelial junctions, gut barrier dysfunction and liver damage in mice.

Mir H, Meena AS, Chaudhry KK, Shukla PK, Gangwar R, Manda B, Padala MK, Shen L, Turner JR, Dietrich P, Dragatsis I, Rao R.

Biochim Biophys Acta. 2016 Apr;1860(4):765-74. doi: 10.1016/j.bbagen.2015.12.013. Epub 2015 Dec 23.


Ammonium salts of carbamodithioic acid as potent vaginal trichomonacides and fungicides.

Kushwaha B, Mandalapu D, Bala V, Kumar L, Pandey A, Pandey D, Yadav SK, Singh P, Shukla PK, Maikhuri JP, Sankhwar SN, Sharma VL, Gupta G.

Int J Antimicrob Agents. 2016 Jan;47(1):36-47. doi: 10.1016/j.ijantimicag.2015.10.022. Epub 2015 Nov 26.


Glutamine supplementation attenuates ethanol-induced disruption of apical junctional complexes in colonic epithelium and ameliorates gut barrier dysfunction and fatty liver in mice.

Chaudhry KK, Shukla PK, Mir H, Manda B, Gangwar R, Yadav N, McMullen M, Nagy LE, Rao R.

J Nutr Biochem. 2016 Jan;27:16-26. doi: 10.1016/j.jnutbio.2015.08.012. Epub 2015 Aug 20.


Innovative Disulfide Esters of Dithiocarbamic Acid as Women-Controlled Contraceptive Microbicides: A Bioisosterism Approach.

Mandalapu D, Lal N, Kumar L, Kushwaha B, Gupta S, Kumar L, Bala V, Yadav SK, Singh P, Singh N, Maikhuri JP, Sankhwar SN, Shukla PK, Siddiqi I, Gupta G, Sharma VL.

ChemMedChem. 2015 Oct;10(10):1739-53. doi: 10.1002/cmdc.201500291. Epub 2015 Sep 4.


N-Alkyl/aryl-4-(3-substituted-3-phenylpropyl)piperazine-1-carbothioamide as dual-action vaginal microbicides with reverse transcriptase inhibition.

Bala V, Mandalapu D, Gupta S, Jangir S, Kushwaha B, Chhonker YS, Chandasana H, Krishna S, Rawat K, Krishna A, Singh M, Sankhwar SN, Shukla PK, Maikhuri JP, Bhatta RS, Siddiqi MI, Tripathi R, Gupta G, Sharma VL.

Eur J Med Chem. 2015 Aug 28;101:640-50. doi: 10.1016/j.ejmech.2015.07.021. Epub 2015 Jul 13.


Novel Chalcone-Thiazole Hybrids as Potent Inhibitors of Drug Resistant Staphylococcus aureus.

Sashidhara KV, Rao KB, Kushwaha P, Modukuri RK, Singh P, Soni I, Shukla PK, Chopra S, Pasupuleti M.

ACS Med Chem Lett. 2015 May 29;6(7):809-13. doi: 10.1021/acsmedchemlett.5b00169. eCollection 2015 Jul 9.


ALDH2 Deficiency Promotes Ethanol-Induced Gut Barrier Dysfunction and Fatty Liver in Mice.

Chaudhry KK, Samak G, Shukla PK, Mir H, Gangwar R, Manda B, Isse T, Kawamoto T, Salaspuro M, Kaihovaara P, Dietrich P, Dragatsis I, Nagy LE, Rao RK.

Alcohol Clin Exp Res. 2015 Aug;39(8):1465-75. doi: 10.1111/acer.12777. Epub 2015 Jul 14.


Host-mediated gene silencing of a single effector gene from the potato pathogen Phytophthora infestans imparts partial resistance to late blight disease.

Sanju S, Siddappa S, Thakur A, Shukla PK, Srivastava N, Pattanayak D, Sharma S, Singh BP.

Funct Integr Genomics. 2015 Nov;15(6):697-706. doi: 10.1007/s10142-015-0446-z. Epub 2015 Jun 16.


Design and synthesis of new fluconazole analogues.

Pore VS, Agalave SG, Singh P, Shukla PK, Kumar V, Siddiqi MI.

Org Biomol Chem. 2015 Jun 21;13(23):6551-61. doi: 10.1039/c5ob00590f. Epub 2015 May 15.


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