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Items: 28

1.

Methyl 5-MeO-N-aminoanthranilate, a minimalist fluorogenic probe for sensing cellular aldehydic load.

Suchý M, Lazurko C, Kirby A, Dang T, Liu G, Shuhendler AJ.

Org Biomol Chem. 2018 Nov 19. doi: 10.1039/c8ob02255k. [Epub ahead of print]

PMID:
30450500
2.

Assessment of tumor redox status through (S)-4-(3-[18F]fluoropropyl)-L-glutamic acid positron emission tomography imaging of system xc- activity.

McCormick PN, Greenwood HE, Glaser M, Maddocks ODK, Gendron T, Sander K, Gowrishankar G, Hoehne A, Zhang T, Shuhendler AJ, Lewis DY, Berndt M, Koglin N, Lythgoe MF, Gambhir SS, Årstad E, Witney TH.

Cancer Res. 2018 Nov 6. pii: canres.2634.2018. doi: 10.1158/0008-5472.CAN-18-2634. [Epub ahead of print]

PMID:
30401715
3.

TSPO-PET imaging using [18F]PBR06 is a potential translatable biomarker for treatment response in Huntington's disease: preclinical evidence with the p75NTR ligand LM11A-31.

Simmons DA, James ML, Belichenko NP, Semaan S, Condon C, Kuan J, Shuhendler AJ, Miao Z, Chin FT, Longo FM.

Hum Mol Genet. 2018 Aug 15;27(16):2893-2912. doi: 10.1093/hmg/ddy202.

4.

Hydrazo-CEST: Hydrazone-Dependent Chemical Exchange Saturation Transfer Magnetic Resonance Imaging Contrast Agents.

Dang T, Suchy M, Truong YJ, Oakden W, Lam WW, Lazurko C, Facey G, Stanisz GJ, Shuhendler AJ.

Chemistry. 2018 Jun 26;24(36):9148-9156. doi: 10.1002/chem.201801671. Epub 2018 Jun 6.

PMID:
29645309
5.

[18F]GE-180 PET Detects Reduced Microglia Activation After LM11A-31 Therapy in a Mouse Model of Alzheimer's Disease.

James ML, Belichenko NP, Shuhendler AJ, Hoehne A, Andrews LE, Condon C, Nguyen TV, Reiser V, Jones P, Trigg W, Rao J, Gambhir SS, Longo FM.

Theranostics. 2017 Mar 24;7(6):1422-1436. doi: 10.7150/thno.17666. eCollection 2017.

6.

Two-photon excitation nanoparticles for photodynamic therapy.

Shen Y, Shuhendler AJ, Ye D, Xu JJ, Chen HY.

Chem Soc Rev. 2016 Dec 21;45(24):6725-6741. Epub 2016 Oct 5. Review.

PMID:
27711672
7.

Molecular Magnetic Resonance Imaging of Tumor Response to Therapy.

Shuhendler AJ, Ye D, Brewer KD, Bazalova-Carter M, Lee KH, Kempen P, Dane Wittrup K, Graves EE, Rutt B, Rao J.

Sci Rep. 2015 Oct 6;5:14759. doi: 10.1038/srep14759.

8.

Further validation to support clinical translation of [(18)F]FTC-146 for imaging sigma-1 receptors.

Shen B, James ML, Andrews L, Lau C, Chen S, Palner M, Miao Z, Arksey NC, Shuhendler AJ, Scatliffe S, Kaneshige K, Parsons SM, McCurdy CR, Salehi A, Gambhir SS, Chin FT.

EJNMMI Res. 2015 Dec;5(1):49. doi: 10.1186/s13550-015-0122-2. Epub 2015 Sep 17.

9.

Diketopyrrolopyrrole-Based Semiconducting Polymer Nanoparticles for In Vivo Photoacoustic Imaging.

Pu K, Mei J, Jokerst JV, Hong G, Antaris AL, Chattopadhyay N, Shuhendler AJ, Kurosawa T, Zhou Y, Gambhir SS, Bao Z, Rao J.

Adv Mater. 2015 Sep 16;27(35):5184-90. doi: 10.1002/adma.201502285. Epub 2015 Aug 6.

10.

Optimizing the design and in vitro evaluation of bioreactive glucose oxidase-microspheres for enhanced cytotoxicity against multidrug resistant breast cancer cells.

Cheng J, Liu Q, Shuhendler AJ, Rauth AM, Wu XY.

Colloids Surf B Biointerfaces. 2015 Jun 1;130:164-72. doi: 10.1016/j.colsurfb.2015.04.002. Epub 2015 Apr 8.

PMID:
25896537
11.

Caspase-responsive smart gadolinium-based contrast agent for magnetic resonance imaging of drug-induced apoptosis.

Ye D, Shuhendler AJ, Pandit P, Brewer KD, Tee SS, Cui L, Tikhomirov G, Rutt B, Rao J.

Chem Sci. 2014 Oct 1;4(10):3845-3852.

12.

Bioorthogonal cyclization-mediated in situ self-assembly of small-molecule probes for imaging caspase activity in vivo.

Ye D, Shuhendler AJ, Cui L, Tong L, Tee SS, Tikhomirov G, Felsher DW, Rao J.

Nat Chem. 2014 Jun;6(6):519-26. doi: 10.1038/nchem.1920. Epub 2014 Apr 28.

13.

Synergistic nanoparticulate drug combination overcomes multidrug resistance, increases efficacy, and reduces cardiotoxicity in a nonimmunocompromised breast tumor model.

Shuhendler AJ, Prasad P, Zhang RX, Amini MA, Sun M, Liu PP, Bristow RG, Rauth AM, Wu XY.

Mol Pharm. 2014 Aug 4;11(8):2659-74. doi: 10.1021/mp500093c. Epub 2014 Jun 3.

PMID:
24830351
14.

Phosphorylcholine-coated semiconducting polymer nanoparticles as rapid and efficient labeling agents for in vivo cell tracking.

Pu K, Shuhendler AJ, Valta MP, Cui L, Saar M, Peehl DM, Rao J.

Adv Healthc Mater. 2014 Aug;3(8):1292-8. doi: 10.1002/adhm.201300534. Epub 2014 Mar 25.

15.

Real-time imaging of oxidative and nitrosative stress in the liver of live animals for drug-toxicity testing.

Shuhendler AJ, Pu K, Cui L, Uetrecht JP, Rao J.

Nat Biotechnol. 2014 Apr;32(4):373-80. doi: 10.1038/nbt.2838. Epub 2014 Mar 23.

16.

Semiconducting polymer nanoparticles as photoacoustic molecular imaging probes in living mice.

Pu K, Shuhendler AJ, Jokerst JV, Mei J, Gambhir SS, Bao Z, Rao J.

Nat Nanotechnol. 2014 Mar;9(3):233-9. doi: 10.1038/nnano.2013.302. Epub 2014 Jan 26.

17.

Semiconducting polymer nanoprobe for in vivo imaging of reactive oxygen and nitrogen species.

Pu K, Shuhendler AJ, Rao J.

Angew Chem Int Ed Engl. 2013 Sep 23;52(39):10325-9. doi: 10.1002/anie.201303420. Epub 2013 Aug 13. No abstract available.

18.

Matrigel alters the pathophysiology of orthotopic human breast adenocarcinoma xenografts with implications for nanomedicine evaluation.

Shuhendler AJ, Prasad P, Cai P, Hui KK, Henderson JT, Rauth AM, Wu XY.

Nanomedicine. 2013 Aug;9(6):795-805. doi: 10.1016/j.nano.2013.01.005. Epub 2013 Feb 19.

PMID:
23434679
19.

A novel solid lipid nanoparticle formulation for active targeting to tumor α(v) β(3) integrin receptors reveals cyclic RGD as a double-edged sword.

Shuhendler AJ, Prasad P, Leung M, Rauth AM, Dacosta RS, Wu XY.

Adv Healthc Mater. 2012 Sep;1(5):600-8. doi: 10.1002/adhm.201200006. Epub 2012 Jul 25.

PMID:
23184795
20.

Self-luminescing BRET-FRET near-infrared dots for in vivo lymph-node mapping and tumour imaging.

Xiong L, Shuhendler AJ, Rao J.

Nat Commun. 2012;3:1193. doi: 10.1038/ncomms2197.

21.

Estimation of minimum doses for optimized quantum dot contrast-enhanced vascular imaging in vivo.

Roy M, Niu CJ, Chen Y, McVeigh PZ, Shuhendler AJ, Leung MK, Mariampillai A, DaCosta RS, Wilson BC.

Small. 2012 Jun 11;8(11):1780-92. doi: 10.1002/smll.201102105. Epub 2012 Mar 19.

PMID:
22431228
22.

Thermally-triggered 'off-on-off' response of gadolinium-hydrogel-lipid hybrid nanoparticles defines a customizable temperature window for non-invasive magnetic resonance imaging thermometry.

Shuhendler AJ, Staruch R, Oakden W, Gordijo CR, Rauth AM, Stanisz GJ, Chopra R, Wu XY.

J Control Release. 2012 Feb 10;157(3):478-84. doi: 10.1016/j.jconrel.2011.09.061. Epub 2011 Sep 10.

PMID:
21939700
23.

Colloidally stable silicon nanocrystals with near-infrared photoluminescence for biological fluorescence imaging.

Henderson EJ, Shuhendler AJ, Prasad P, Baumann V, Maier-Flaig F, Faulkner DO, Lemmer U, Wu XY, Ozin GA.

Small. 2011 Sep 5;7(17):2507-16. doi: 10.1002/smll.201100845. Epub 2011 Jul 8.

PMID:
21739601
24.

Hybrid quantum dot-fatty ester stealth nanoparticles: toward clinically relevant in vivo optical imaging of deep tissue.

Shuhendler AJ, Prasad P, Chan HK, Gordijo CR, Soroushian B, Kolios M, Yu K, O'Brien PJ, Rauth AM, Wu XY.

ACS Nano. 2011 Mar 22;5(3):1958-66. doi: 10.1021/nn103024b. Epub 2011 Feb 21.

PMID:
21338075
25.

Efficacy of botulinum toxin type A for the prophylaxis of episodic migraine headaches: a meta-analysis of randomized, double-blind, placebo-controlled trials.

Shuhendler AJ, Lee S, Siu M, Ondovcik S, Lam K, Alabdullatif A, Zhang X, Machado M, Einarson TR.

Pharmacotherapy. 2009 Jul;29(7):784-91. doi: 10.1592/phco.29.7.784.

PMID:
19558252
26.

A novel doxorubicin-mitomycin C co-encapsulated nanoparticle formulation exhibits anti-cancer synergy in multidrug resistant human breast cancer cells.

Shuhendler AJ, Cheung RY, Manias J, Connor A, Rauth AM, Wu XY.

Breast Cancer Res Treat. 2010 Jan;119(2):255-69. doi: 10.1007/s10549-008-0271-3. Epub 2009 Feb 17.

PMID:
19221875
27.

On the synergistic effect of doxorubicin and mitomycin C against breast cancer cells.

Shuhendler AJ, O'Brien PJ, Rauth AM, Wu XY.

Drug Metabol Drug Interact. 2007;22(4):201-33.

PMID:
18447000
28.

Molecular interactions, internal structure and drug release kinetics of rationally developed polymer-lipid hybrid nanoparticles.

Li Y, Wong HL, Shuhendler AJ, Rauth AM, Wu XY.

J Control Release. 2008 May 22;128(1):60-70. doi: 10.1016/j.jconrel.2008.02.014. Epub 2008 Mar 5.

PMID:
18406489

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