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Items: 43

1.

Merkel Cell Polyomavirus Downregulates N-myc Downstream-Regulated Gene 1, Leading to Cellular Proliferation and Migration.

Gupta P, Shahzad N, Harold A, Shuda M, Venuti A, Romero-Medina MC, Pacini L, Brault L, Robitaille A, Taverniti V, Hernandez-Vargas H, Durand G, Le Calvez-Kelm F, Gheit T, Accardi R, Tommasino M.

J Virol. 2020 Jan 17;94(3). pii: e00899-19. doi: 10.1128/JVI.00899-19. Print 2020 Jan 17.

PMID:
31694959
2.

Conversion of Sox2-dependent Merkel cell carcinoma to a differentiated neuron-like phenotype by T antigen inhibition.

Harold A, Amako Y, Hachisuka J, Bai Y, Li MY, Kubat L, Gravemeyer J, Franks J, Gibbs JR, Park HJ, Ezhkova E, Becker JC, Shuda M.

Proc Natl Acad Sci U S A. 2019 Oct 1;116(40):20104-20114. doi: 10.1073/pnas.1907154116. Epub 2019 Sep 16.

3.

MCPyV Large T Antigen-Induced Atonal Homolog 1 Is a Lineage-Dependency Oncogene in Merkel Cell Carcinoma.

Fan K, Gravemeyer J, Ritter C, Rasheed K, Gambichler T, Moens U, Shuda M, Schrama D, Becker JC.

J Invest Dermatol. 2020 Jan;140(1):56-65.e3. doi: 10.1016/j.jid.2019.06.135. Epub 2019 Jul 5.

PMID:
31283928
4.

Production and characterization of monoclonal antibodies specific for major capsid VP1 protein of trichodysplasia spinulosa-associated polyomavirus.

Khatun H, Yamaoka Y, Matsushima Y, Matsunaga S, Kimura H, Ho J, Shuda M, Ryo A.

Microbiol Immunol. 2018 Dec;62(12):763-773. doi: 10.1111/1348-0421.12662.

PMID:
30537287
5.

Characterization of a Merkel Cell Polyomavirus-Positive Merkel Cell Carcinoma Cell Line CVG-1.

Velásquez C, Amako Y, Harold A, Toptan T, Chang Y, Shuda M.

Front Microbiol. 2018 Apr 11;9:713. doi: 10.3389/fmicb.2018.00713. eCollection 2018.

6.

Mitotic protein kinase CDK1 phosphorylation of mRNA translation regulator 4E-BP1 Ser83 may contribute to cell transformation.

Velásquez C, Cheng E, Shuda M, Lee-Oesterreich PJ, Pogge von Strandmann L, Gritsenko MA, Jacobs JM, Moore PS, Chang Y.

Proc Natl Acad Sci U S A. 2016 Jul 26;113(30):8466-71. doi: 10.1073/pnas.1607768113. Epub 2016 Jul 11.

7.

Strategies for Human Tumor Virus Discoveries: From Microscopic Observation to Digital Transcriptome Subtraction.

Mirvish ED, Shuda M.

Front Microbiol. 2016 May 13;7:676. doi: 10.3389/fmicb.2016.00676. eCollection 2016. Review.

8.

Merkel Cell Polyomavirus Small T Antigen Induces Cancer and Embryonic Merkel Cell Proliferation in a Transgenic Mouse Model.

Shuda M, Guastafierro A, Geng X, Shuda Y, Ostrowski SM, Lukianov S, Jenkins FJ, Honda K, Maricich SM, Moore PS, Chang Y.

PLoS One. 2015 Nov 6;10(11):e0142329. doi: 10.1371/journal.pone.0142329. eCollection 2015.

9.

Mitotic 4E-BP1 hyperphosphorylation and cap-dependent translation.

Shuda M, Chang Y, Moore PS.

Cell Cycle. 2015;14(19):3005-6. doi: 10.1080/15384101.2015.1084192. No abstract available.

10.

Merkel cell polyomavirus T antigens promote cell proliferation and inflammatory cytokine gene expression.

Richards KF, Guastafierro A, Shuda M, Toptan T, Moore PS, Chang Y.

J Gen Virol. 2015 Dec;96(12):3532-44.

11.

CDK1 substitutes for mTOR kinase to activate mitotic cap-dependent protein translation.

Shuda M, Velásquez C, Cheng E, Cordek DG, Kwun HJ, Chang Y, Moore PS.

Proc Natl Acad Sci U S A. 2015 May 12;112(19):5875-82. doi: 10.1073/pnas.1505787112. Epub 2015 Apr 16.

12.

Restricted protein phosphatase 2A targeting by Merkel cell polyomavirus small T antigen.

Kwun HJ, Shuda M, Camacho CJ, Gamper AM, Thant M, Chang Y, Moore PS.

J Virol. 2015 Apr;89(8):4191-200. doi: 10.1128/JVI.00157-15. Epub 2015 Jan 28.

13.

A novel strategy for targeted killing of tumor cells: Induction of multipolar acentrosomal mitotic spindles with a quinazolinone derivative mdivi-1.

Wang J, Li J, Santana-Santos L, Shuda M, Sobol RW, Van Houten B, Qian W.

Mol Oncol. 2015 Feb;9(2):488-502. doi: 10.1016/j.molonc.2014.10.002. Epub 2014 Oct 17.

14.

Merkel cell polyomavirus-positive Merkel cell carcinoma requires viral small T-antigen for cell proliferation.

Shuda M, Chang Y, Moore PS.

J Invest Dermatol. 2014 May;134(5):1479-1481. doi: 10.1038/jid.2013.483. Epub 2013 Nov 12. No abstract available.

15.

The T antigen locus of Merkel cell polyomavirus downregulates human Toll-like receptor 9 expression.

Shahzad N, Shuda M, Gheit T, Kwun HJ, Cornet I, Saidj D, Zannetti C, Hasan U, Chang Y, Moore PS, Accardi R, Tommasino M.

J Virol. 2013 Dec;87(23):13009-19. doi: 10.1128/JVI.01786-13. Epub 2013 Sep 25.

16.

Merkel cell polyomavirus small T antigen controls viral replication and oncoprotein expression by targeting the cellular ubiquitin ligase SCFFbw7.

Kwun HJ, Shuda M, Feng H, Camacho CJ, Moore PS, Chang Y.

Cell Host Microbe. 2013 Aug 14;14(2):125-35. doi: 10.1016/j.chom.2013.06.008.

17.

Merkel cell polyomavirus and non-small cell lung cancer.

Shuda M, Feng H, Moore PS, Chang Y.

Br J Cancer. 2013 Jun 25;108(12):2623. doi: 10.1038/bjc.2013.195. Epub 2013 Jun 4. No abstract available.

18.

Multicolor microRNA FISH effectively differentiates tumor types.

Renwick N, Cekan P, Masry PA, McGeary SE, Miller JB, Hafner M, Li Z, Mihailovic A, Morozov P, Brown M, Gogakos T, Mobin MB, Snorrason EL, Feilotter HE, Zhang X, Perlis CS, Wu H, Suárez-Fariñas M, Feng H, Shuda M, Moore PS, Tron VA, Chang Y, Tuschl T.

J Clin Invest. 2013 Jun;123(6):2694-702.

19.

Characterization of an early passage Merkel cell polyomavirus-positive Merkel cell carcinoma cell line, MS-1, and its growth in NOD scid gamma mice.

Guastafierro A, Feng H, Thant M, Kirkwood JM, Chang Y, Moore PS, Shuda M.

J Virol Methods. 2013 Jan;187(1):6-14. doi: 10.1016/j.jviromet.2012.10.001. Epub 2012 Oct 18.

20.

Survivin is a therapeutic target in Merkel cell carcinoma.

Arora R, Shuda M, Guastafierro A, Feng H, Toptan T, Tolstov Y, Normolle D, Vollmer LL, Vogt A, Dömling A, Brodsky JL, Chang Y, Moore PS.

Sci Transl Med. 2012 May 9;4(133):133ra56. doi: 10.1126/scitranslmed.3003713.

21.

Human Merkel cell polyomavirus small T antigen is an oncoprotein targeting the 4E-BP1 translation regulator.

Shuda M, Kwun HJ, Feng H, Chang Y, Moore PS.

J Clin Invest. 2011 Sep;121(9):3623-34. doi: 10.1172/JCI46323. Epub 2011 Aug 15.

22.

Merkel cell polyomavirus status is not associated with clinical course of Merkel cell carcinoma.

Schrama D, Peitsch WK, Zapatka M, Kneitz H, Houben R, Eib S, Haferkamp S, Moore PS, Shuda M, Thompson JF, Trefzer U, Pföhler C, Scolyer RA, Becker JC.

J Invest Dermatol. 2011 Aug;131(8):1631-8. doi: 10.1038/jid.2011.115. Epub 2011 May 12.

23.

Merkel cell polyomavirus-infected Merkel cell carcinoma cells require expression of viral T antigens.

Houben R, Shuda M, Weinkam R, Schrama D, Feng H, Chang Y, Moore PS, Becker JC.

J Virol. 2010 Jul;84(14):7064-72. doi: 10.1128/JVI.02400-09. Epub 2010 May 5.

24.

Hepatitis C virus impairs p53 via persistent overexpression of 3beta-hydroxysterol Delta24-reductase.

Nishimura T, Kohara M, Izumi K, Kasama Y, Hirata Y, Huang Y, Shuda M, Mukaidani C, Takano T, Tokunaga Y, Nuriya H, Satoh M, Saito M, Kai C, Tsukiyama-Kohara K.

J Biol Chem. 2009 Dec 25;284(52):36442-52. doi: 10.1074/jbc.M109.043232. Epub 2009 Oct 27.

25.

The minimum replication origin of merkel cell polyomavirus has a unique large T-antigen loading architecture and requires small T-antigen expression for optimal replication.

Kwun HJ, Guastafierro A, Shuda M, Meinke G, Bohm A, Moore PS, Chang Y.

J Virol. 2009 Dec;83(23):12118-28. doi: 10.1128/JVI.01336-09. Epub 2009 Sep 16.

26.

Human Merkel cell polyomavirus infection I. MCV T antigen expression in Merkel cell carcinoma, lymphoid tissues and lymphoid tumors.

Shuda M, Arora R, Kwun HJ, Feng H, Sarid R, Fernández-Figueras MT, Tolstov Y, Gjoerup O, Mansukhani MM, Swerdlow SH, Chaudhary PM, Kirkwood JM, Nalesnik MA, Kant JA, Weiss LM, Moore PS, Chang Y.

Int J Cancer. 2009 Sep 15;125(6):1243-9. doi: 10.1002/ijc.24510.

27.

T antigen mutations are a human tumor-specific signature for Merkel cell polyomavirus.

Shuda M, Feng H, Kwun HJ, Rosen ST, Gjoerup O, Moore PS, Chang Y.

Proc Natl Acad Sci U S A. 2008 Oct 21;105(42):16272-7. doi: 10.1073/pnas.0806526105. Epub 2008 Sep 23.

28.

Clonal integration of a polyomavirus in human Merkel cell carcinoma.

Feng H, Shuda M, Chang Y, Moore PS.

Science. 2008 Feb 22;319(5866):1096-100. doi: 10.1126/science.1152586. Epub 2008 Jan 17.

29.

Activation of Galectin-1 gene in human hepatocellular carcinoma involves methylation-sensitive complex formations at the transcriptional upstream and downstream elements.

Kondoh N, Hada A, Ryo A, Shuda M, Arai M, Matsubara O, Kimura F, Wakatsuki T, Yamamoto M.

Int J Oncol. 2003 Dec;23(6):1575-83.

PMID:
14612929
30.

Identification of epilepsy-related genes by gene expression profiling in the hippocampus of genetically epileptic rat.

Arai M, Amano S, Ryo A, Hada A, Wakatsuki T, Shuda M, Kondoh N, Yamamoto M.

Brain Res Mol Brain Res. 2003 Oct 21;118(1-2):147-51.

PMID:
14559364
31.

Activation of the ATF6, XBP1 and grp78 genes in human hepatocellular carcinoma: a possible involvement of the ER stress pathway in hepatocarcinogenesis.

Shuda M, Kondoh N, Imazeki N, Tanaka K, Okada T, Mori K, Hada A, Arai M, Wakatsuki T, Matsubara O, Yamamoto N, Yamamoto M.

J Hepatol. 2003 May;38(5):605-14.

PMID:
12713871
32.

Activation of anchorage-independent growth of HT1080 human fibrosarcoma cells by dexamethasone.

Kondoh N, Shuda M, Arai M, Oikawa T, Yamamoto M.

In Vitro Cell Dev Biol Anim. 2002 Feb;38(2):111-7.

PMID:
11928993
33.

Enhanced expression of S8, L12, L23a, L27 and L30 ribosomal protein mRNAs in human hepatocellular carcinoma.

Kondoh N, Shuda M, Tanaka K, Wakatsuki T, Hada A, Yamamoto M.

Anticancer Res. 2001 Jul-Aug;21(4A):2429-33.

PMID:
11724303
34.

Genetic and epigenetic events in human hepatocarcinogenesis.

Kondoh N, Wakatsuki T, Hada A, Shuda M, Tanaka K, Arai M, Yamamoto M.

Int J Oncol. 2001 Jun;18(6):1271-8. Review.

PMID:
11351262
35.

Enhanced expression of mRNAs of antisecretory factor-1, gp96, DAD1 and CDC34 in human hepatocellular carcinomas.

Tanaka K, Kondoh N, Shuda M, Matsubara O, Imazeki N, Ryo A, Wakatsuki T, Hada A, Goseki N, Igari T, Hatsuse K, Aihara T, Horiuchi S, Yamamoto N, Yamamoto M.

Biochim Biophys Acta. 2001 Apr 30;1536(1):1-12.

36.

Enhanced expression of translation factor mRNAs in hepatocellular carcinoma.

Shuda M, Kondoh N, Tanaka K, Ryo A, Wakatsuki T, Hada A, Goseki N, Igari T, Hatsuse K, Aihara T, Horiuchi S, Shichita M, Yamamoto N, Yamamoto M.

Anticancer Res. 2000 Jul-Aug;20(4):2489-94.

PMID:
10953316
37.

Identification and characterization of differentially expressed mRNAs in HIV type 1-infected human T cells.

Ryo A, Suzuki Y, Arai M, Kondoh N, Wakatsuki T, Hada A, Shuda M, Tanaka K, Sato C, Yamamoto M, Yamamoto N.

AIDS Res Hum Retroviruses. 2000 Jul 1;16(10):995-1005.

PMID:
10890361
38.

Backbone NMR assignment and secondary structure of ribosome recycling factor (RRF) from Pseudomonas aeruginosa.

Kashimori H, Yoshida T, Kijima H, Shimahara H, Uchiyama S, Ishino T, Shuda M, Nakano H, Shibata Y, Saihara Y, Ohkubo T, Yoshida T, Kaji A, Kobayashi Y.

J Biomol NMR. 1999 Dec;15(4):341-2. No abstract available.

PMID:
10685343
39.

Identification and characterization of genes associated with human hepatocellular carcinogenesis.

Kondoh N, Wakatsuki T, Ryo A, Hada A, Aihara T, Horiuchi S, Goseki N, Matsubara O, Takenaka K, Shichita M, Tanaka K, Shuda M, Yamamoto M.

Cancer Res. 1999 Oct 1;59(19):4990-6.

40.

Plant ribosome recycling factor homologue is a chloroplastic protein and is bactericidal in escherichia coli carrying temperature-sensitive ribosome recycling factor.

Rolland N, Janosi L, Block MA, Shuda M, Teyssier E, Miège C, Chéniclet C, Carde JP, Kaji A, Joyard J.

Proc Natl Acad Sci U S A. 1999 May 11;96(10):5464-9.

41.

Molecular cloning, sequencing, purification, and characterization of Pseudomonas aeruginosa ribosome recycling factor.

Ohnishi M, Janosi L, Shuda M, Matsumoto H, Hayashi T, Terawaki Y, Kaji A.

J Bacteriol. 1999 Feb;181(4):1281-91.

42.

Release factor RF-3 GTPase activity acts in disassembly of the ribosome termination complex.

Grentzmann G, Kelly PJ, Laalami S, Shuda M, Firpo MA, Cenatiempo Y, Kaji A.

RNA. 1998 Aug;4(8):973-83.

43.

Evidence for in vivo ribosome recycling, the fourth step in protein biosynthesis.

Janosi L, Mottagui-Tabar S, Isaksson LA, Sekine Y, Ohtsubo E, Zhang S, Goon S, Nelken S, Shuda M, Kaji A.

EMBO J. 1998 Feb 16;17(4):1141-51.

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