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Items: 1 to 50 of 91

1.

Impairment of cholinergic bladder contractility in rat model of type I diabetes complicated by cystitis: Contribution of neurotransmitter-degrading ectoenzymes.

Vladimirova IA, Philyppov IB, Sotkis GV, Kulieva EM, Shuba YY, Gulak KL, Skryma R, Prevarskaya N, Shuba YM.

Eur J Pharmacol. 2019 Jul 9:172529. doi: 10.1016/j.ejphar.2019.172529. [Epub ahead of print]

PMID:
31299187
2.

A-Kinase-Anchoring Protein (AKAP150) is expressed in Astrocytes and Upregulated in Response to Ischemia.

Rivera-Pagán AF, Méndez-González MP, Rivera-Aponte DE, Malpica-Nieves CJ, Melnik-Martínez KV, Zayas-Santiago A, Maldonado-Martínez G, Shuba YM, Skatchkov SN, Eaton MJ.

Neuroscience. 2018 Aug 1;384:54-63. doi: 10.1016/j.neuroscience.2018.05.019. Epub 2018 May 23.

PMID:
29800717
3.

Ion Channels in Cancer: Are Cancer Hallmarks Oncochannelopathies?

Prevarskaya N, Skryma R, Shuba Y.

Physiol Rev. 2018 Apr 1;98(2):559-621. doi: 10.1152/physrev.00044.2016. Review.

4.

TRPV1 alterations in urinary bladder dysfunction in a rat model of STZ-induced diabetes.

Sharopov BR, Gulak KL, Philyppov IB, Sotkis AV, Shuba YM.

Life Sci. 2018 Jan 15;193:207-213. doi: 10.1016/j.lfs.2017.10.042. Epub 2017 Oct 31.

PMID:
29100756
5.

Myorelaxant action of fluorine-containing pinacidil analog, flocalin, in bladder smooth muscle is mediated by inhibition of L-type calcium channels rather than activation of KATP channels.

Philyppov IB, Golub AА, Boldyriev OI, Shtefan NL, Totska K, Voitychuk OI, Shuba YM.

Naunyn Schmiedebergs Arch Pharmacol. 2016 Jun;389(6):585-92. doi: 10.1007/s00210-016-1228-4. Epub 2016 Mar 15.

PMID:
26976335
6.

TRPA1-dependent regulation of bladder detrusor smooth muscle contractility in normal and type I diabetic rats.

Philyppov IB, Paduraru ON, Gulak KL, Skryma R, Prevarskaya N, Shuba YM.

J Smooth Muscle Res. 2016;52:1-17. doi: 10.1540/jsmr.52.1.

7.

Compensatory reduction of Cav3.1 expression in thalamocortical neurons of juvenile rats of WAG/Rij model of absence epilepsy.

Sharop BR, Boldyriev OI, Batiuk MY, Shtefan NL, Shuba YM.

Epilepsy Res. 2016 Jan;119:10-2. doi: 10.1016/j.eplepsyres.2015.11.008. Epub 2015 Nov 12.

PMID:
26656778
8.

[Impact of diabetic complications on neuromuscular transmission in the smooth muscle of the bladder of rats with experimental diabetes].

Vladimirova IA, Philyppov IB, Kulieva EM, Paduraru ON, Shuba YY, Shuba YM.

Fiziol Zh. 2015;61(4):56-62. Ukrainian. No abstract available.

PMID:
26552306
9.

Assessment of gold nanoparticle effect on prostate cancer LNCaP cells.

Reznikov AG, Salivonyk OA, Sotkis AG, Shuba YM.

Exp Oncol. 2015 Jun;37(2):100-4.

PMID:
26112935
10.

Disrupting the dynamic equilibrium of ORAI channels determines the phenotype of malignant cells.

Vanden Abeele F, Dubois C, Shuba Y, Prevarskaya N.

Mol Cell Oncol. 2015 Jan 21;2(2):e975631. doi: 10.4161/23723556.2014.975631. eCollection 2015 Apr-Jun.

11.

Effects of cannabidiol on contractions and calcium signaling in rat ventricular myocytes.

Ali RM, Al Kury LT, Yang KH, Qureshi A, Rajesh M, Galadari S, Shuba YM, Howarth FC, Oz M.

Cell Calcium. 2015 Apr;57(4):290-9. doi: 10.1016/j.ceca.2015.02.001. Epub 2015 Feb 9.

12.

Remodeling of channel-forming ORAI proteins determines an oncogenic switch in prostate cancer.

Dubois C, Vanden Abeele F, Lehen'kyi V, Gkika D, Guarmit B, Lepage G, Slomianny C, Borowiec AS, Bidaux G, Benahmed M, Shuba Y, Prevarskaya N.

Cancer Cell. 2014 Jul 14;26(1):19-32. doi: 10.1016/j.ccr.2014.04.025. Epub 2014 Jun 19.

13.

Effects of the endogenous cannabinoid anandamide on voltage-dependent sodium and calcium channels in rat ventricular myocytes.

Al Kury LT, Voitychuk OI, Yang KH, Thayyullathil FT, Doroshenko P, Ramez AM, Shuba YM, Galadari S, Howarth FC, Oz M.

Br J Pharmacol. 2014 Jul;171(14):3485-98. doi: 10.1111/bph.12734.

14.

Effects of endogenous cannabinoid anandamide on cardiac Na⁺/Ca²⁺ exchanger.

Al Kury LT, Yang KH, Thayyullathil FT, Rajesh M, Ali RM, Shuba YM, Howarth FC, Galadari S, Oz M.

Cell Calcium. 2014 May;55(5):231-7. doi: 10.1016/j.ceca.2014.02.017. Epub 2014 Mar 11.

PMID:
24674601
15.

Remodelling of Ca2+ transport in cancer: how it contributes to cancer hallmarks?

Prevarskaya N, Ouadid-Ahidouch H, Skryma R, Shuba Y.

Philos Trans R Soc Lond B Biol Sci. 2014 Feb 3;369(1638):20130097. doi: 10.1098/rstb.2013.0097. Print 2014 Mar 19. Review.

16.

Effects of endogenous cannabinoid anandamide on excitation-contraction coupling in rat ventricular myocytes.

Al Kury LT, Voitychuk OI, Ali RM, Galadari S, Yang KH, Howarth FC, Shuba YM, Oz M.

Cell Calcium. 2014 Feb;55(2):104-18. doi: 10.1016/j.ceca.2013.12.005. Epub 2014 Jan 5.

PMID:
24472666
17.

Models of calcium permeation through T-type channels.

Shuba YM.

Pflugers Arch. 2014 Apr;466(4):635-44. doi: 10.1007/s00424-013-1437-3. Epub 2014 Jan 22. Review.

PMID:
24449276
18.

Frequency dependence of excitation-contraction of multicellular smooth muscle preparations: the relevance to bipolar electrosurgery.

Vladimirova IA, Lankin YN, Philyppov IB, Sushiy LF, Shuba YM.

J Surg Res. 2014 Jan;186(1):119-25. doi: 10.1016/j.jss.2013.08.012. Epub 2013 Sep 3.

PMID:
24157266
19.

Menthol inhibits 5-HT3 receptor-mediated currents.

Ashoor A, Nordman JC, Veltri D, Yang KH, Shuba Y, Al Kury L, Sadek B, Howarth FC, Shehu A, Kabbani N, Oz M.

J Pharmacol Exp Ther. 2013 Nov;347(2):398-409. doi: 10.1124/jpet.113.203976. Epub 2013 Aug 21. Erratum in: J Pharmacol Exp Ther. 2013 Dec;347(3):816.

PMID:
23965380
20.

Complex modulation of the cold receptor TRPM8 by volatile anaesthetics and its role in complications of general anaesthesia.

Vanden Abeele F, Kondratskyi A, Dubois C, Shapovalov G, Gkika D, Busserolles J, Shuba Y, Skryma R, Prevarskaya N.

J Cell Sci. 2013 Oct 1;126(Pt 19):4479-89. doi: 10.1242/jcs.131631. Epub 2013 Aug 13.

21.

Menthol binding and inhibition of α7-nicotinic acetylcholine receptors.

Ashoor A, Nordman JC, Veltri D, Yang KH, Al Kury L, Shuba Y, Mahgoub M, Howarth FC, Sadek B, Shehu A, Kabbani N, Oz M.

PLoS One. 2013 Jul 23;8(7):e67674. doi: 10.1371/journal.pone.0067674. Print 2013.

22.

Targeting Ca²⁺ transport in cancer: close reality or long perspective?

Prevarskaya N, Skryma R, Shuba Y.

Expert Opin Ther Targets. 2013 Mar;17(3):225-41. doi: 10.1517/14728222.2013.741594. Epub 2013 Jan 7. Review.

PMID:
23294334
23.

Complex modulation of Ca(v)3.1 T-type calcium channel by nickel.

Nosal OV, Lyubanova OP, Naidenov VG, Shuba YM.

Cell Mol Life Sci. 2013 May;70(9):1653-61. doi: 10.1007/s00018-012-1225-9. Epub 2012 Dec 19.

PMID:
23250353
24.

Modulation of TRPV1-dependent contractility of normal and diabetic bladder smooth muscle by analgesic toxins from sea anemone Heteractis crispa.

Philyppov IB, Paduraru ON, Andreev YA, Grishin EV, Shuba YM.

Life Sci. 2012 Nov 2;91(19-20):912-20. doi: 10.1016/j.lfs.2012.09.001. Epub 2012 Sep 12.

PMID:
22982418
25.

Effects of fluorine-containing opener of ATP-sensitive potassium channels, pinacidil-derivative flocalin, on cardiac voltage-gated sodium and calcium channels.

Voitychuk OI, Strutynskyi RB, Moibenko OO, Shuba YM.

Naunyn Schmiedebergs Arch Pharmacol. 2012 Nov;385(11):1095-102. doi: 10.1007/s00210-012-0792-5. Epub 2012 Sep 8.

PMID:
22960704
26.

Modulation of excitability, membrane currents and survival of cardiac myocytes by N-acylethanolamines.

Voitychuk OI, Asmolkova VS, Gula NM, Sotkis GV, Galadari S, Howarth FC, Oz M, Shuba YM.

Biochim Biophys Acta. 2012 Sep;1821(9):1167-76. doi: 10.1016/j.bbalip.2012.05.003. Epub 2012 May 18.

PMID:
22613942
27.

Regulation of activity of transient receptor potential melastatin 8 (TRPM8) channel by its short isoforms.

Bidaux G, Beck B, Zholos A, Gordienko D, Lemonnier L, Flourakis M, Roudbaraki M, Borowiec AS, Fernández J, Delcourt P, Lepage G, Shuba Y, Skryma R, Prevarskaya N.

J Biol Chem. 2012 Jan 27;287(5):2948-62. doi: 10.1074/jbc.M111.270256. Epub 2011 Nov 28.

28.

From urgency to frequency: facts and controversies of TRPs in the lower urinary tract.

Skryma R, Prevarskaya N, Gkika D, Shuba Y.

Nat Rev Urol. 2011 Oct 4;8(11):617-30. doi: 10.1038/nrurol.2011.142. Review.

PMID:
21971315
29.

Calcium in tumour metastasis: new roles for known actors.

Prevarskaya N, Skryma R, Shuba Y.

Nat Rev Cancer. 2011 Jul 22;11(8):609-18. doi: 10.1038/nrc3105. Review.

PMID:
21779011
30.

Orai1 contributes to the establishment of an apoptosis-resistant phenotype in prostate cancer cells.

Flourakis M, Lehen'kyi V, Beck B, Raphaël M, Vandenberghe M, Abeele FV, Roudbaraki M, Lepage G, Mauroy B, Romanin C, Shuba Y, Skryma R, Prevarskaya N.

Cell Death Dis. 2010 Sep 16;1:e75. doi: 10.1038/cddis.2010.52.

31.

Complex regulation of the TRPM8 cold receptor channel: role of arachidonic acid release following M3 muscarinic receptor stimulation.

Bavencoffe A, Kondratskyi A, Gkika D, Mauroy B, Shuba Y, Prevarskaya N, Skryma R.

J Biol Chem. 2011 Mar 18;286(11):9849-55. doi: 10.1074/jbc.M110.162016. Epub 2011 Jan 18.

32.

Sarcolemmal cardiac K(ATP) channels as a target for the cardioprotective effects of the fluorine-containing pinacidil analogue, flocalin.

Voitychuk OI, Strutynskyi RB, Yagupolskii LM, Tinker A, Moibenko OO, Shuba YM.

Br J Pharmacol. 2011 Feb;162(3):701-11. doi: 10.1111/j.1476-5381.2010.01072.x.

33.

The effects of anandamide transport inhibitor AM404 on voltage-dependent calcium channels.

Alptekin A, Galadari S, Shuba Y, Petroianu G, Oz M.

Eur J Pharmacol. 2010 May 25;634(1-3):10-5. doi: 10.1016/j.ejphar.2010.02.013. Epub 2010 Feb 17.

PMID:
20171208
34.

Ion channels and the hallmarks of cancer.

Prevarskaya N, Skryma R, Shuba Y.

Trends Mol Med. 2010 Mar;16(3):107-21. doi: 10.1016/j.molmed.2010.01.005. Epub 2010 Feb 16. Review.

PMID:
20167536
35.

The transient receptor potential channel TRPM8 is inhibited via the alpha 2A adrenoreceptor signaling pathway.

Bavencoffe A, Gkika D, Kondratskyi A, Beck B, Borowiec AS, Bidaux G, Busserolles J, Eschalier A, Shuba Y, Skryma R, Prevarskaya N.

J Biol Chem. 2010 Mar 26;285(13):9410-9. doi: 10.1074/jbc.M109.069377. Epub 2010 Jan 28.

36.

The endogenous cannabinoid, anandamide, inhibits dopamine transporter function by a receptor-independent mechanism.

Oz M, Jaligam V, Galadari S, Petroianu G, Shuba YM, Shippenberg TS.

J Neurochem. 2010 Mar;112(6):1454-64. doi: 10.1111/j.1471-4159.2009.06557.x. Epub 2009 Dec 24.

37.

Ischemia Increases TREK-2 Channel Expression in Astrocytes: Relevance to Glutamate Clearance.

Kucheryavykh LY, Kucheryavykh YV, Inyushin M, Shuba YM, Sanabria P, Cubano LA, Skatchkov SN, Eaton MJ.

Open Neurosci J. 2009 Jan 1;3:40-47.

38.

Modulation by testosterone of an endogenous hERG potassium channel current.

Ridley JM, Shuba YM, James AF, Hancox JC.

J Physiol Pharmacol. 2008 Sep;59(3):395-407.

39.

T-type calcium channels: from discovery to channelopathies, 25 years of research.

Shuba YM, Perez-Reyes E, Lory P, Noebels J.

Channels (Austin). 2008 Jul-Aug;2(4):299-302. Epub 2008 Jul 10. No abstract available.

PMID:
18769138
40.

Local extracellular acidification caused by Ca2+-dependent exocytosis in PC12 cells.

Shuba YM, Dietrich CJ, Oermann E, Cleemann L, Morad M.

Cell Calcium. 2008 Aug;44(2):220-9. doi: 10.1016/j.ceca.2007.12.003. Epub 2008 Mar 17.

PMID:
18346783
41.

Complex rectification of Müller cell Kir currents.

Kucheryavykh YV, Shuba YM, Antonov SM, Inyushin MY, Cubano L, Pearson WL, Kurata H, Reichenbach A, Veh RW, Nichols CG, Eaton MJ, Skatchkov SN.

Glia. 2008 May;56(7):775-90. doi: 10.1002/glia.20652.

PMID:
18293411
42.

Calcium signalling and cancer cell growth.

Capiod T, Shuba Y, Skryma R, Prevarskaya N.

Subcell Biochem. 2007;45:405-27. Review.

PMID:
18193646
43.

Prostate cell differentiation status determines transient receptor potential melastatin member 8 channel subcellular localization and function.

Bidaux G, Flourakis M, Thebault S, Zholos A, Beck B, Gkika D, Roudbaraki M, Bonnal JL, Mauroy B, Shuba Y, Skryma R, Prevarskaya N.

J Clin Invest. 2007 Jun;117(6):1647-57. Epub 2007 May 17.

44.

Ion channels in death and differentiation of prostate cancer cells.

Prevarskaya N, Skryma R, Bidaux G, Flourakis M, Shuba Y.

Cell Death Differ. 2007 Jul;14(7):1295-304. Epub 2007 May 4. Review.

45.

Selectivity signatures of three isoforms of recombinant T-type Ca2+ channels.

Shcheglovitov A, Kostyuk P, Shuba Y.

Biochim Biophys Acta. 2007 Jun;1768(6):1406-19. Epub 2007 Mar 1.

46.

Ca2+-independent phospholipase A2-dependent gating of TRPM8 by lysophospholipids.

Vanden Abeele F, Zholos A, Bidaux G, Shuba Y, Thebault S, Beck B, Flourakis M, Panchin Y, Skryma R, Prevarskaya N.

J Biol Chem. 2006 Dec 29;281(52):40174-82. Epub 2006 Nov 2.

47.

Prospects for prostate cancer imaging and therapy using high-affinity TRPM8 activators.

Beck B, Bidaux G, Bavencoffe A, Lemonnier L, Thebault S, Shuba Y, Barrit G, Skryma R, Prevarskaya N.

Cell Calcium. 2007 Mar;41(3):285-94. Epub 2006 Sep 1.

PMID:
16949669
48.

Differential role of transient receptor potential channels in Ca2+ entry and proliferation of prostate cancer epithelial cells.

Thebault S, Flourakis M, Vanoverberghe K, Vandermoere F, Roudbaraki M, Lehen'kyi V, Slomianny C, Beck B, Mariot P, Bonnal JL, Mauroy B, Shuba Y, Capiod T, Skryma R, Prevarskaya N.

Cancer Res. 2006 Feb 15;66(4):2038-47.

49.

Tandem-pore domain potassium channels are functionally expressed in retinal (Müller) glial cells.

Skatchkov SN, Eaton MJ, Shuba YM, Kucheryavykh YV, Derst C, Veh RW, Wurm A, Iandiev I, Pannicke T, Bringmann A, Reichenbach A.

Glia. 2006 Feb;53(3):266-76.

PMID:
16265669
50.

Novel role of cold/menthol-sensitive transient receptor potential melastatine family member 8 (TRPM8) in the activation of store-operated channels in LNCaP human prostate cancer epithelial cells.

Thebault S, Lemonnier L, Bidaux G, Flourakis M, Bavencoffe A, Gordienko D, Roudbaraki M, Delcourt P, Panchin Y, Shuba Y, Skryma R, Prevarskaya N.

J Biol Chem. 2005 Nov 25;280(47):39423-35. Epub 2005 Sep 20.

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