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Items: 1 to 50 of 167

1.

Krüppel-like Factor 5 Regulates Stemness, Lineage Specification, and Regeneration of Intestinal Epithelial Stem Cells.

Kim CK, Saxena M, Maharjan K, Song JJ, Shroyer KR, Bialkowska AB, Shivdasani RA, Yang VW.

Cell Mol Gastroenterol Hepatol. 2019 Nov 25. pii: S2352-345X(19)30164-X. doi: 10.1016/j.jcmgh.2019.11.009. [Epub ahead of print]

2.

Initial studies with [11C]vorozole positron emission tomography detect over-expression of intra-tumoral aromatase in breast cancer.

Biegon A, Shroyer KR, Franceschi D, Dhawan J, Tahmi M, Pareto D, Bonilla P, Airola K, Cohen J.

J Nucl Med. 2019 Nov 22. pii: jnumed.119.231589. doi: 10.2967/jnumed.119.231589. [Epub ahead of print]

PMID:
31757843
3.

Keratin 17 is a negative prognostic biomarker in high-grade endometrial carcinomas.

Bai JDK, Babu S, Roa-Peña L, Hou W, Akalin A, Escobar-Hoyos LF, Shroyer KR.

Hum Pathol. 2019 Dec;94:40-50. doi: 10.1016/j.humpath.2019.09.005. Epub 2019 Oct 23.

PMID:
31655172
4.

Keratin 17 identifies the most lethal molecular subtype of pancreatic cancer.

Roa-Peña L, Leiton CV, Babu S, Pan CH, Vanner EA, Akalin A, Bandovic J, Moffitt RA, Shroyer KR, Escobar-Hoyos LF.

Sci Rep. 2019 Aug 2;9(1):11239. doi: 10.1038/s41598-019-47519-4.

5.

Oncogenic KRAS Reduces Expression of FGF21 in Acinar Cells to Promote Pancreatic Tumorigenesis in Mice on a High-Fat Diet.

Luo Y, Yang Y, Liu M, Wang D, Wang F, Bi Y, Ji J, Li S, Liu Y, Chen R, Huang H, Wang X, Swidnicka-Siergiejko AK, Janowitz T, Beyaz S, Wang G, Xu S, Bialkowska AB, Luo CK, Pin CL, Liang G, Lu X, Wu M, Shroyer KR, Wolff RA, Plunkett W, Ji B, Li Z, Li E, Li X, Yang VW, Logsdon CD, Abbruzzese JL, Lu W.

Gastroenterology. 2019 Nov;157(5):1413-1428.e11. doi: 10.1053/j.gastro.2019.07.030. Epub 2019 Jul 25.

PMID:
31352001
6.

Overview of established and emerging immunohistochemical biomarkers and their role in correlative studies in MRI.

Alvi E, Gupta R, Borok RZ, Escobar-Hoyos L, Shroyer KR.

J Magn Reson Imaging. 2020 Feb;51(2):341-354. doi: 10.1002/jmri.26763. Epub 2019 Apr 30. Review.

PMID:
31041822
7.

RPGRIP1L is required for stabilizing epidermal keratinocyte adhesion through regulating desmoglein endocytosis.

Choi YJ, Laclef C, Yang N, Andreu-Cervera A, Lewis J, Mao X, Li L, Snedecor ER, Takemaru KI, Qin C, Schneider-Maunoury S, Shroyer KR, Hannun YA, Koch PJ, Clark RA, Payne AS, Kowalczyk AP, Chen J.

PLoS Genet. 2019 Jan 28;15(1):e1007914. doi: 10.1371/journal.pgen.1007914. eCollection 2019 Jan.

8.

Keratin 17 is a sensitive and specific biomarker of urothelial neoplasia.

Babu S, Mockler DC, Roa-Peña L, Szygalowicz A, Kim NW, Jahanfard S, Gholami SS, Moffitt R, Fitzgerald JP, Escobar-Hoyos LF, Shroyer KR.

Mod Pathol. 2019 May;32(5):717-724. doi: 10.1038/s41379-018-0177-5. Epub 2018 Nov 15.

PMID:
30443013
9.

Direct therapeutic targeting of immune checkpoint PD-1 in pancreatic cancer.

Gao M, Lin M, Moffitt RA, Salazar MA, Park J, Vacirca J, Huang C, Shroyer KR, Choi M, Georgakis GV, Sasson AR, Talamini MA, Kim J.

Br J Cancer. 2019 Jan;120(1):88-96. doi: 10.1038/s41416-018-0298-0. Epub 2018 Oct 31.

10.

Increased Genetic Instability and Accelerated Progression of Colitis-Associated Colorectal Cancer through Intestinal Epithelium-specific Deletion of Klf4.

Yang VW, Liu Y, Kim J, Shroyer KR, Bialkowska AB.

Mol Cancer Res. 2019 Jan;17(1):165-176. doi: 10.1158/1541-7786.MCR-18-0399. Epub 2018 Aug 14.

11.

Establishment of three novel cell lines derived from African American patients with colorectal carcinoma: A unique tool for assessing racial health disparity.

Paredes J, Ji P, Lacomb JF, Shroyer KR, Martello LA, Williams JL.

Int J Oncol. 2018 Oct;53(4):1516-1528. doi: 10.3892/ijo.2018.4510. Epub 2018 Jul 31.

12.

Development of Patient-Derived Gastric Cancer Organoids from Endoscopic Biopsies and Surgical Tissues.

Gao M, Lin M, Rao M, Thompson H, Hirai K, Choi M, Georgakis GV, Sasson AR, Bucobo JC, Tzimas D, D'Souza LS, Buscaglia JM, Davis J, Shroyer KR, Li J, Powers S, Kim J.

Ann Surg Oncol. 2018 Sep;25(9):2767-2775. doi: 10.1245/s10434-018-6662-8. Epub 2018 Jul 12.

PMID:
30003451
13.

Elevated expression of keratin 17 in oropharyngeal squamous cell carcinoma is associated with decreased survival.

Regenbogen E, Mo M, Romeiser J, Shroyer ALW, Escobar-Hoyos LF, Burke S, Shroyer KR.

Head Neck. 2018 Aug;40(8):1788-1798. doi: 10.1002/hed.25164. Epub 2018 Apr 6.

PMID:
29626364
14.

Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images.

Saltz J, Gupta R, Hou L, Kurc T, Singh P, Nguyen V, Samaras D, Shroyer KR, Zhao T, Batiste R, Van Arnam J; Cancer Genome Atlas Research Network, Shmulevich I, Rao AUK, Lazar AJ, Sharma A, Thorsson V.

Cell Rep. 2018 Apr 3;23(1):181-193.e7. doi: 10.1016/j.celrep.2018.03.086.

15.

B7-H4 is Inversely Correlated With T-Cell Infiltration in Clear Cell but Not Serous or Endometrioid Ovarian Cancer.

Pagnotti GM, Atkinson RM, Romeiser J, Akalin A, Korman MB, Shroyer KR.

Appl Immunohistochem Mol Morphol. 2019 Aug;27(7):515-522. doi: 10.1097/PAI.0000000000000608.

PMID:
29189263
16.

Keratin 17 Is a Prognostic Biomarker in Endocervical Glandular Neoplasia.

Mockler D, Escobar-Hoyos LF, Akalin A, Romeiser J, Shroyer AL, Shroyer KR.

Am J Clin Pathol. 2017 Sep 1;148(3):264-273. doi: 10.1093/ajcp/aqx077.

PMID:
28821199
17.

P38 delta MAPK promotes breast cancer progression and lung metastasis by enhancing cell proliferation and cell detachment.

Wada M, Canals D, Adada M, Coant N, Salama MF, Helke KL, Arthur JS, Shroyer KR, Kitatani K, Obeid LM, Hannun YA.

Oncogene. 2017 Nov 23;36(47):6649-6657. doi: 10.1038/onc.2017.274. Epub 2017 Aug 7.

18.

Strategies for building a successful ultrasound guided FNA practice in department of pathology-Experience at a university hospital.

Wu M, Shroyer KR.

Diagn Cytopathol. 2017 Oct;45(10):878-882. doi: 10.1002/dc.23784. Epub 2017 Jul 11.

PMID:
28699306
19.

INTU is essential for oncogenic Hh signaling through regulating primary cilia formation in basal cell carcinoma.

Yang N, Leung EL, Liu C, Li L, Eguether T, Jun Yao XJ, Jones EC, Norris DA, Liu A, Clark RA, Roop DR, Pazour GJ, Shroyer KR, Chen J.

Oncogene. 2017 Aug 31;36(35):4997-5005. doi: 10.1038/onc.2017.117. Epub 2017 May 1.

20.

Safety and Efficacy of A High Performance Graphene-Based Magnetic Resonance Imaging Contrast Agent for Renal Abnormalities.

Kanakia S, Toussaint J, Kukarni P, Lee S, Chowdhury SM, Khan S, Mallipattu SK, Shroyer KR, Moore W, Sitharaman B.

Graphene Technol. 2016 Dec;1(1):17-28. doi: 10.1007/s41127-016-0001-2. Epub 2016 Aug 3.

21.

Keratin 17 is overexpressed and predicts poor survival in estrogen receptor-negative/human epidermal growth factor receptor-2-negative breast cancer.

Merkin RD, Vanner EA, Romeiser JL, Shroyer ALW, Escobar-Hoyos LF, Li J, Powers RS, Burke S, Shroyer KR.

Hum Pathol. 2017 Apr;62:23-32. doi: 10.1016/j.humpath.2016.10.006. Epub 2016 Nov 2.

PMID:
27816721
22.

The effect of sleeve gastrectomy on extraesophageal reflux disease.

Frenkel C, Telem DA, Pryor AD, Altieri MS, Shroyer KR, Regenbogen E.

Surg Obes Relat Dis. 2016 Aug;12(7):1263-1269. doi: 10.1016/j.soard.2015.11.002. Epub 2015 Nov 10.

PMID:
26965156
23.

Low intensity vibration mitigates tumor progression and protects bone quantity and quality in a murine model of myeloma.

Pagnotti GM, Chan ME, Adler BJ, Shroyer KR, Rubin J, Bain SD, Rubin CT.

Bone. 2016 Sep;90:69-79. doi: 10.1016/j.bone.2016.05.014. Epub 2016 Jun 2.

24.

Gorab Is Required for Dermal Condensate Cells to Respond to Hedgehog Signals during Hair Follicle Morphogenesis.

Liu Y, Snedecor ER, Choi YJ, Yang N, Zhang X, Xu Y, Han Y, Jones EC, Shroyer KR, Clark RA, Zhang L, Qin C, Chen J.

J Invest Dermatol. 2016 Feb;136(2):378-386. doi: 10.1016/j.jid.2015.10.067. Epub 2015 Nov 24. Review.

25.

Unmet clinical needs in cervical cancer screening.

Rao J, Escobar-Hoyos L, Shroyer KR.

MLO Med Lab Obs. 2016 Jan;48(1):8, 10, 14; quiz 15.

PMID:
26887092
26.

Ablation of Neuropilin 1 from glioma-associated microglia and macrophages slows tumor progression.

Miyauchi JT, Chen D, Choi M, Nissen JC, Shroyer KR, Djordevic S, Zachary IC, Selwood D, Tsirka SE.

Oncotarget. 2016 Mar 1;7(9):9801-14. doi: 10.18632/oncotarget.6877.

27.

Towards An Advanced Graphene-Based Magnetic Resonance Imaging Contrast Agent: Sub-acute Toxicity and Efficacy Studies in Small Animals.

Kanakia S, Toussaint J, Hoang DM, Mullick Chowdhury S, Lee S, Shroyer KR, Moore W, Wadghiri YZ, Sitharaman B.

Sci Rep. 2015 Dec 2;5:17182. doi: 10.1038/srep17182.

28.

ML264, A Novel Small-Molecule Compound That Potently Inhibits Growth of Colorectal Cancer.

Ruiz de Sabando A, Wang C, He Y, García-Barros M, Kim J, Shroyer KR, Bannister TD, Yang VW, Bialkowska AB.

Mol Cancer Ther. 2016 Jan;15(1):72-83. doi: 10.1158/1535-7163.MCT-15-0600. Epub 2015 Nov 30.

29.

PEPCK Coordinates the Regulation of Central Carbon Metabolism to Promote Cancer Cell Growth.

Montal ED, Dewi R, Bhalla K, Ou L, Hwang BJ, Ropell AE, Gordon C, Liu WJ, DeBerardinis RJ, Sudderth J, Twaddel W, Boros LG, Shroyer KR, Duraisamy S, Drapkin R, Powers RS, Rohde JM, Boxer MB, Wong KK, Girnun GD.

Mol Cell. 2015 Nov 19;60(4):571-83. doi: 10.1016/j.molcel.2015.09.025. Epub 2015 Oct 17.

30.

Keratin-17 Promotes p27KIP1 Nuclear Export and Degradation and Offers Potential Prognostic Utility.

Escobar-Hoyos LF, Shah R, Roa-Peña L, Vanner EA, Najafian N, Banach A, Nielsen E, Al-Khalil R, Akalin A, Talmage D, Shroyer KR.

Cancer Res. 2015 Sep 1;75(17):3650-62. doi: 10.1158/0008-5472.CAN-15-0293. Epub 2015 Jun 24.

31.

The association between sleeve gastrectomy and histopathologic changes consistent with esophagitis in a rodent model.

Altieri MS, Shroyer KR, Pryor A, Pagnotti GM, Ete Chan M, Talamini M, Telem DA.

Surg Obes Relat Dis. 2015 Nov-Dec;11(6):1289-94. doi: 10.1016/j.soard.2015.01.012. Epub 2015 Jan 23.

PMID:
26048523
32.

Hypoxia promotes colon cancer dissemination through up-regulation of cell migration-inducing protein (CEMIP).

Evensen NA, Li Y, Kuscu C, Liu J, Cathcart J, Banach A, Zhang Q, Li E, Joshi S, Yang J, Denoya PI, Pastorekova S, Zucker S, Shroyer KR, Cao J.

Oncotarget. 2015 Aug 21;6(24):20723-39.

33.

miR-181a-5p Inhibits Cancer Cell Migration and Angiogenesis via Downregulation of Matrix Metalloproteinase-14.

Li Y, Kuscu C, Banach A, Zhang Q, Pulkoski-Gross A, Kim D, Liu J, Roth E, Li E, Shroyer KR, Denoya PI, Zhu X, Chen L, Cao J.

Cancer Res. 2015 Jul 1;75(13):2674-85. doi: 10.1158/0008-5472.CAN-14-2875. Epub 2015 May 14.

34.

Loss of primary cilia in melanoma cells is likely independent of proliferation and cell cycle progression.

Snedecor ER, Sung CC, Moncayo A, Rothstein BE, Mockler DC, Tonnesen MG, Jones EC, Fujita M, Clark RA, Shroyer KR, Chen J.

J Invest Dermatol. 2015 May;135(5):1456-1458. doi: 10.1038/jid.2015.22. Epub 2015 Jan 28. No abstract available.

35.

Comments on "HPV and lung cancer risk: a meta-analysis" [Zhai et al., J. Clin. Virol. (in press)].

Vanner EA, Shroyer KR.

J Clin Virol. 2015 Feb;63:91. doi: 10.1016/j.jcv.2014.11.019. Epub 2014 Nov 20. No abstract available.

PMID:
25466494
36.

Establishment of highly tumorigenic human colorectal cancer cell line (CR4) with properties of putative cancer stem cells.

Rowehl RA, Burke S, Bialkowska AB, Pettet DW 3rd, Rowehl L, Li E, Antoniou E, Zhang Y, Bergamaschi R, Shroyer KR, Ojima I, Botchkina GI.

PLoS One. 2014 Jun 12;9(6):e99091. doi: 10.1371/journal.pone.0099091. eCollection 2014.

37.

Differential expression of miRNAs in colon cancer between African and Caucasian Americans: implications for cancer racial health disparities.

Li E, Ji P, Ouyang N, Zhang Y, Wang XY, Rubin DC, Davidson NO, Bergamaschi R, Shroyer KR, Burke S, Zhu W, Williams JL.

Int J Oncol. 2014 Aug;45(2):587-94. doi: 10.3892/ijo.2014.2469. Epub 2014 May 27.

38.

Dose ranging, expanded acute toxicity and safety pharmacology studies for intravenously administered functionalized graphene nanoparticle formulations.

Kanakia S, Toussaint JD, Mullick Chowdhury S, Tembulkar T, Lee S, Jiang YP, Lin RZ, Shroyer KR, Moore W, Sitharaman B.

Biomaterials. 2014 Aug;35(25):7022-31. doi: 10.1016/j.biomaterials.2014.04.066. Epub 2014 May 20.

39.

Inducible intestine-specific deletion of Krüppel-like factor 5 is characterized by a regenerative response in adult mouse colon.

Nandan MO, Ghaleb AM, Liu Y, Bialkowska AB, McConnell BB, Shroyer KR, Robine S, Yang VW.

Dev Biol. 2014 Mar 15;387(2):191-202. doi: 10.1016/j.ydbio.2014.01.002. Epub 2014 Jan 15.

40.

Development of a conditional Mesd (mesoderm development) allele for functional analysis of the low-density lipoprotein receptor-related family in defined tissues.

Taibi AV, Lighthouse JK, Grady RC, Shroyer KR, Holdener BC.

PLoS One. 2013 Oct 4;8(10):e75782. doi: 10.1371/journal.pone.0075782. eCollection 2013.

41.

Prostate cancer stem cell-targeted efficacy of a new-generation taxoid, SBT-1214 and novel polyenolic zinc-binding curcuminoid, CMC2.24.

Botchkina GI, Zuniga ES, Rowehl RH, Park R, Bhalla R, Bialkowska AB, Johnson F, Golub LM, Zhang Y, Ojima I, Shroyer KR.

PLoS One. 2013 Sep 24;8(9):e69884. doi: 10.1371/journal.pone.0069884. eCollection 2013.

42.

Keratin 17 in premalignant and malignant squamous lesions of the cervix: proteomic discovery and immunohistochemical validation as a diagnostic and prognostic biomarker.

Escobar-Hoyos LF, Yang J, Zhu J, Cavallo JA, Zhai H, Burke S, Koller A, Chen EI, Shroyer KR.

Mod Pathol. 2014 Apr;27(4):621-30. doi: 10.1038/modpathol.2013.166. Epub 2013 Sep 20.

43.

In vitro hematological and in vivo vasoactivity assessment of dextran functionalized graphene.

Chowdhury SM, Kanakia S, Toussaint JD, Frame MD, Dewar AM, Shroyer KR, Moore W, Sitharaman B.

Sci Rep. 2013;3:2584. doi: 10.1038/srep02584.

44.

Physicochemical characterization of a novel graphene-based magnetic resonance imaging contrast agent.

Kanakia S, Toussaint JD, Chowdhury SM, Lalwani G, Tembulkar T, Button T, Shroyer KR, Moore W, Sitharaman B.

Int J Nanomedicine. 2013;8:2821-33. doi: 10.2147/IJN.S47062. Epub 2013 Aug 5.

45.

Ron tyrosine kinase receptor synergises with EGFR to confer adverse features in head and neck squamous cell carcinoma.

Keller J, Nimnual AS, Shroyer KR, Joy C, Ischenko I, Chandler CS, Dong LM, Hayman MJ, Chan EL.

Br J Cancer. 2013 Jul 23;109(2):482-92. doi: 10.1038/bjc.2013.321. Epub 2013 Jun 25.

46.

Toward single-walled carbon nanotube-gadolinium complex as advanced MRI contrast agents: pharmacodynamics and global genomic response in small animals.

Avti PK, Talukdar Y, Sirotkin MV, Shroyer KR, Sitharaman B.

J Biomed Mater Res B Appl Biomater. 2013 Aug;101(6):1039-49. doi: 10.1002/jbm.b.32914. Epub 2013 Apr 4.

47.

Immunohistochemical localization of HE4 in benign, borderline, and malignant lesions of the ovary.

Georgakopoulos P, Mehmood S, Akalin A, Shroyer KR.

Int J Gynecol Pathol. 2012 Nov;31(6):517-23. doi: 10.1097/PGP.0b013e31824fe269.

PMID:
23018214
48.

Use of telecytology for the immediate assessment of CT guided and endoscopic FNA cytology: diagnostic accuracy, advantages, and pitfalls.

Heimann A, Maini G, Hwang S, Shroyer KR, Singh M.

Diagn Cytopathol. 2012 Jul;40(7):575-81. doi: 10.1002/dc.21582. Epub 2010 Dec 31.

PMID:
22707323
49.

Low magnitude mechanical signals mitigate osteopenia without compromising longevity in an aged murine model of spontaneous granulosa cell ovarian cancer.

Pagnotti GM, Adler BJ, Green DE, Chan ME, Frechette DM, Shroyer KR, Beamer WG, Rubin J, Rubin CT.

Bone. 2012 Sep;51(3):570-7. doi: 10.1016/j.bone.2012.05.004. Epub 2012 May 11.

50.

Prognostic significance of miR-205 in endometrial cancer.

Karaayvaz M, Zhang C, Liang S, Shroyer KR, Ju J.

PLoS One. 2012;7(4):e35158. doi: 10.1371/journal.pone.0035158. Epub 2012 Apr 13.

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