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Items: 13


MYC oncogene overexpression drives renal cell carcinoma in a mouse model through glutamine metabolism.

Shroff EH, Eberlin LS, Dang VM, Gouw AM, Gabay M, Adam SJ, Bellovin DI, Tran PT, Philbrick WM, Garcia-Ocana A, Casey SC, Li Y, Dang CV, Zare RN, Felsher DW.

Proc Natl Acad Sci U S A. 2015 May 26;112(21):6539-44. doi: 10.1073/pnas.1507228112. Epub 2015 May 11.


Characterization of MYC-induced tumorigenesis by in situ lipid profiling.

Perry RH, Bellovin DI, Shroff EH, Ismail AI, Zabuawala T, Felsher DW, Zare RN.

Anal Chem. 2013 May 7;85(9):4259-62. doi: 10.1021/ac400479j. Epub 2013 Apr 18.


Twist1 suppresses senescence programs and thereby accelerates and maintains mutant Kras-induced lung tumorigenesis.

Tran PT, Shroff EH, Burns TF, Thiyagarajan S, Das ST, Zabuawala T, Chen J, Cho YJ, Luong R, Tamayo P, Salih T, Aziz K, Adam SJ, Vicent S, Nielsen CH, Withofs N, Sweet-Cordero A, Gambhir SS, Rudin CM, Felsher DW.

PLoS Genet. 2012;8(5):e1002650. doi: 10.1371/journal.pgen.1002650. Epub 2012 May 24.


High throughput automated chromatin immunoprecipitation as a platform for drug screening and antibody validation.

Wu AR, Kawahara TL, Rapicavoli NA, van Riggelen J, Shroff EH, Xu L, Felsher DW, Chang HY, Quake SR.

Lab Chip. 2012 Jun 21;12(12):2190-8. doi: 10.1039/c2lc21290k. Epub 2012 May 8.


Nitric oxide induces cell death by regulating anti-apoptotic BCL-2 family members.

Snyder CM, Shroff EH, Liu J, Chandel NS.

PLoS One. 2009 Sep 21;4(9):e7059. doi: 10.1371/journal.pone.0007059.


BH3 peptides induce mitochondrial fission and cell death independent of BAX/BAK.

Shroff EH, Snyder CM, Budinger GR, Jain M, Chew TL, Khuon S, Perlman H, Chandel NS.

PLoS One. 2009 May 21;4(5):e5646. doi: 10.1371/journal.pone.0005646.


Hyperoxia-induced premature senescence requires p53 and pRb, but not mitochondrial matrix ROS.

Klimova TA, Bell EL, Shroff EH, Weinberg FD, Snyder CM, Dimri GP, Schumacker PT, Budinger GR, Chandel NS.

FASEB J. 2009 Mar;23(3):783-94. doi: 10.1096/fj.08-114256. Epub 2008 Oct 23.


Bcl-2 family members regulate anoxia-induced cell death.

Shroff EH, Snyder C, Chandel NS.

Antioxid Redox Signal. 2007 Sep;9(9):1405-9. Review.


Role of Bcl-2 family members in anoxia induced cell death.

Shroff EH, Snyder C, Chandel NS.

Cell Cycle. 2007 Apr 1;6(7):807-9. Epub 2007 Apr 22. Review.


Loss of Mcl-1 protein and inhibition of electron transport chain together induce anoxic cell death.

Brunelle JK, Shroff EH, Perlman H, Strasser A, Moraes CT, Flavell RA, Danial NN, Keith B, Thompson CB, Chandel NS.

Mol Cell Biol. 2007 Feb;27(4):1222-35. Epub 2006 Dec 4.


Two functional epitopes of pigment epithelial-derived factor block angiogenesis and induce differentiation in prostate cancer.

Filleur S, Volz K, Nelius T, Mirochnik Y, Huang H, Zaichuk TA, Aymerich MS, Becerra SP, Yap R, Veliceasa D, Shroff EH, Volpert OV.

Cancer Res. 2005 Jun 15;65(12):5144-52.


Peroxisome proliferator-activated receptor gamma ligands improve the antitumor efficacy of thrombospondin peptide ABT510.

Huang H, Campbell SC, Bedford DF, Nelius T, Veliceasa D, Shroff EH, Henkin J, Schneider A, Bouck N, Volpert OV.

Mol Cancer Res. 2004 Oct;2(10):541-50.


Nuclear factor of activated T cells balances angiogenesis activation and inhibition.

Zaichuk TA, Shroff EH, Emmanuel R, Filleur S, Nelius T, Volpert OV.

J Exp Med. 2004 Jun 7;199(11):1513-22.

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