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Items: 1 to 50 of 128

1.

NK Response Correlates with HIV Decrease in Pegylated IFN-α2a-Treated Antiretroviral Therapy-Suppressed Subjects.

Papasavvas E, Azzoni L, Kossenkov AV, Dawany N, Morales KH, Fair M, Ross BN, Lynn K, Mackiewicz A, Mounzer K, Tebas P, Jacobson JM, Kostman JR, Showe L, Montaner LJ.

J Immunol. 2019 Jun 28. pii: ji1801511. doi: 10.4049/jimmunol.1801511. [Epub ahead of print]

PMID:
31253727
2.

N6-Methylation of Adenosine of FZD10 mRNA Contributes to PARP Inhibitor Resistance.

Fukumoto T, Zhu H, Nacarelli T, Karakashev S, Fatkhutdinov N, Wu S, Liu P, Kossenkov AV, Showe LC, Jean S, Zhang L, Zhang R.

Cancer Res. 2019 Jun 1;79(11):2812-2820. doi: 10.1158/0008-5472.CAN-18-3592. Epub 2019 Apr 9.

PMID:
30967398
3.

A Gene Expression Classifier from Whole Blood Distinguishes Benign from Malignant Lung Nodules Detected by Low-Dose CT.

Kossenkov AV, Qureshi R, Dawany NB, Wickramasinghe J, Liu Q, Majumdar RS, Chang C, Widura S, Kumar T, Horng WH, Konnisto E, Criner G, Tsay JJ, Pass H, Yendamuri S, Vachani A, Bauer T, Nam B, Rom WN, Showe MK, Showe LC.

Cancer Res. 2019 Jan 1;79(1):263-273. doi: 10.1158/0008-5472.CAN-18-2032. Epub 2018 Nov 28.

PMID:
30487137
4.

The effect of timing of influenza vaccination and sample collection on antibody titers and responses in the aged.

Kurupati RK, Kossenkoff A, Kannan S, Haut LH, Doyle S, Yin X, Schmader KE, Liu Q, Showe L, Ertl HCJ.

Vaccine. 2017 Jun 27;35(30):3700-3708. doi: 10.1016/j.vaccine.2017.05.074. Epub 2017 Jun 2.

PMID:
28583307
5.

ADAR1 controls apoptosis of stressed cells by inhibiting Staufen1-mediated mRNA decay.

Sakurai M, Shiromoto Y, Ota H, Song C, Kossenkov AV, Wickramasinghe J, Showe LC, Skordalakes E, Tang HY, Speicher DW, Nishikura K.

Nat Struct Mol Biol. 2017 Jun;24(6):534-543. doi: 10.1038/nsmb.3403. Epub 2017 Apr 24.

6.

Structural and functional analysis of the human POT1-TPP1 telomeric complex.

Rice C, Shastrula PK, Kossenkov AV, Hills R, Baird DM, Showe LC, Doukov T, Janicki S, Skordalakes E.

Nat Commun. 2017 Apr 10;8:14928. doi: 10.1038/ncomms14928.

7.
8.

BET Inhibitors Suppress ALDH Activity by Targeting ALDH1A1 Super-Enhancer in Ovarian Cancer.

Yokoyama Y, Zhu H, Lee JH, Kossenkov AV, Wu SY, Wickramasinghe JM, Yin X, Palozola KC, Gardini A, Showe LC, Zaret KS, Liu Q, Speicher D, Conejo-Garcia JR, Bradner JE, Zhang Z, Sood AK, Ordog T, Bitler BG, Zhang R.

Cancer Res. 2016 Nov 1;76(21):6320-6330.

9.

TIGIT and Helios Are Highly Expressed on CD4+ T Cells in Sézary Syndrome Patients.

Jariwala N, Benoit B, Kossenkov AV, Oetjen LK, Whelan TM, Cornejo CM, Takeshita J, Kim BS, Showe LC, Wysocka M, Rook AH.

J Invest Dermatol. 2017 Jan;137(1):257-260. doi: 10.1016/j.jid.2016.08.016. Epub 2016 Sep 1. No abstract available.

10.

Transgenic Expression of the Mitochondrial Chaperone TNFR-associated Protein 1 (TRAP1) Accelerates Prostate Cancer Development.

Lisanti S, Garlick DS, Bryant KG, Tavecchio M, Mills GB, Lu Y, Kossenkov AV, Showe LC, Languino LR, Altieri DC.

J Biol Chem. 2016 Nov 25;291(48):25247-25254. Epub 2016 Oct 17.

11.

Race-related differences in antibody responses to the inactivated influenza vaccine are linked to distinct pre-vaccination gene expression profiles in blood.

Kurupati R, Kossenkov A, Haut L, Kannan S, Xiang Z, Li Y, Doyle S, Liu Q, Schmader K, Showe L, Ertl H.

Oncotarget. 2016 Sep 27;7(39):62898-62911. doi: 10.18632/oncotarget.11704.

12.

Age-related changes in the transcriptome of antibody-secreting cells.

Kannan S, Dawany N, Kurupati R, Showe LC, Ertl HC.

Oncotarget. 2016 Mar 22;7(12):13340-53. doi: 10.18632/oncotarget.7958.

13.

The mRNA-edited form of GABRA3 suppresses GABRA3-mediated Akt activation and breast cancer metastasis.

Gumireddy K, Li A, Kossenkov AV, Sakurai M, Yan J, Li Y, Xu H, Wang J, Zhang PJ, Zhang L, Showe LC, Nishikura K, Huang Q.

Nat Commun. 2016 Feb 12;7:10715. doi: 10.1038/ncomms10715.

14.

Telomeric repeat-containing RNA (TERRA) constitutes a nucleoprotein component of extracellular inflammatory exosomes.

Wang Z, Deng Z, Dahmane N, Tsai K, Wang P, Williams DR, Kossenkov AV, Showe LC, Zhang R, Huang Q, Conejo-Garcia JR, Lieberman PM.

Proc Natl Acad Sci U S A. 2015 Nov 17;112(46):E6293-300. doi: 10.1073/pnas.1505962112. Epub 2015 Nov 2.

15.

HIV-1-negative female sex workers sustain high cervical IFNɛ, low immune activation, and low expression of HIV-1-required host genes.

Abdulhaqq SA, Zorrilla C, Kang G, Yin X, Tamayo V, Seaton KE, Joseph J, Garced S, Tomaras GD, Linn KA, Foulkes AS, Azzoni L, VerMilyea M, Coutifaris C, Kossenkov AV, Showe L, Kraiselburd EN, Li Q, Montaner LJ.

Mucosal Immunol. 2016 Jul;9(4):1027-38. doi: 10.1038/mi.2015.116. Epub 2015 Nov 11.

16.

In-Depth, Label-Free Analysis of the Erythrocyte Cytoplasmic Proteome in Diamond Blackfan Anemia Identifies a Unique Inflammatory Signature.

Pesciotta EN, Lam HS, Kossenkov A, Ge J, Showe LC, Mason PJ, Bessler M, Speicher DW.

PLoS One. 2015 Oct 16;10(10):e0140036. doi: 10.1371/journal.pone.0140036. eCollection 2015.

17.

Identification of MEF2B, EBF1, and IL6R as Direct Gene Targets of Epstein-Barr Virus (EBV) Nuclear Antigen 1 Critical for EBV-Infected B-Lymphocyte Survival.

Tempera I, De Leo A, Kossenkov AV, Cesaroni M, Song H, Dawany N, Showe L, Lu F, Wikramasinghe P, Lieberman PM.

J Virol. 2015 Oct 14;90(1):345-55. doi: 10.1128/JVI.02318-15. Print 2016 Jan 1.

18.

Interaction between TBP and Condensin Drives the Organization and Faithful Segregation of Mitotic Chromosomes.

Iwasaki O, Tanizawa H, Kim KD, Yokoyama Y, Corcoran CJ, Tanaka A, Skordalakes E, Showe LC, Noma K.

Mol Cell. 2015 Sep 3;59(5):755-67. doi: 10.1016/j.molcel.2015.07.007. Epub 2015 Aug 6.

19.

AKAP4 is a circulating biomarker for non-small cell lung cancer.

Gumireddy K, Li A, Chang DH, Liu Q, Kossenkov AV, Yan J, Korst RJ, Nam BT, Xu H, Zhang L, Ganepola GA, Showe LC, Huang Q.

Oncotarget. 2015 Jul 10;6(19):17637-47.

20.

Romidepsin in peripheral and cutaneous T-cell lymphoma: mechanistic implications from clinical and correlative data.

Bates SE, Eisch R, Ling A, Rosing D, Turner M, Pittaluga S, Prince HM, Kirschbaum MH, Allen SL, Zain J, Geskin LJ, Joske D, Popplewell L, Cowen EW, Jaffe ES, Nichols J, Kennedy S, Steinberg SM, Liewehr DJ, Showe LC, Steakley C, Wright J, Fojo T, Litman T, Piekarz RL.

Br J Haematol. 2015 Jul;170(1):96-109. doi: 10.1111/bjh.13400. Epub 2015 Apr 19.

21.

Effects of pro-inflammatory cytokines on cannabinoid CB1 and CB2 receptors in immune cells.

Jean-Gilles L, Braitch M, Latif ML, Aram J, Fahey AJ, Edwards LJ, Robins RA, Tanasescu R, Tighe PJ, Gran B, Showe LC, Alexander SP, Chapman V, Kendall DA, Constantinescu CS.

Acta Physiol (Oxf). 2015 May;214(1):63-74. doi: 10.1111/apha.12474. Epub 2015 Mar 10.

22.

Comparative functional genomics of adaptation to muscular disuse in hibernating mammals.

Fedorov VB, Goropashnaya AV, Stewart NC, Tøien Ø, Chang C, Wang H, Yan J, Showe LC, Showe MK, Barnes BM.

Mol Ecol. 2014 Nov;23(22):5524-37. doi: 10.1111/mec.12963. Epub 2014 Nov 3.

23.

Inflammation and Its Correlates in Regenerative Wound Healing: An Alternate Perspective.

Gourevitch D, Kossenkov AV, Zhang Y, Clark L, Chang C, Showe LC, Heber-Katz E.

Adv Wound Care (New Rochelle). 2014 Sep 1;3(9):592-603. Review.

24.

ID1 promotes breast cancer metastasis by S100A9 regulation.

Gumireddy K, Li A, Kossenkov AV, Cai KQ, Liu Q, Yan J, Xu H, Showe L, Zhang L, Huang Q.

Mol Cancer Res. 2014 Sep;12(9):1334-43. doi: 10.1158/1541-7786.MCR-14-0049. Epub 2014 Jun 19.

25.

The transcription factor Foxp1 is a critical negative regulator of the differentiation of follicular helper T cells.

Wang H, Geng J, Wen X, Bi E, Kossenkov AV, Wolf AI, Tas J, Choi YS, Takata H, Day TJ, Chang LY, Sprout SL, Becker EK, Willen J, Tian L, Wang X, Xiao C, Jiang P, Crotty S, Victora GD, Showe LC, Tucker HO, Erikson J, Hu H.

Nat Immunol. 2014 Jul;15(7):667-75. doi: 10.1038/ni.2890. Epub 2014 May 25.

26.

Identification of a 251 gene expression signature that can accurately detect M. tuberculosis in patients with and without HIV co-infection.

Dawany N, Showe LC, Kossenkov AV, Chang C, Ive P, Conradie F, Stevens W, Sanne I, Azzoni L, Montaner LJ.

PLoS One. 2014 Feb 25;9(2):e89925. doi: 10.1371/journal.pone.0089925. eCollection 2014.

27.

Fine-mapping quantitative trait loci affecting murine external ear tissue regeneration in the LG/J by SM/J advanced intercross line.

Cheverud JM, Lawson HA, Bouckaert K, Kossenkov AV, Showe LC, Cort L, Blankenhorn EP, Bedelbaeva K, Gourevitch D, Zhang Y, Heber-Katz E.

Heredity (Edinb). 2014 May;112(5):508-18. doi: 10.1038/hdy.2013.133. Epub 2014 Feb 26.

28.

Isoform-level gene signature improves prognostic stratification and accurately classifies glioblastoma subtypes.

Pal S, Bi Y, Macyszyn L, Showe LC, O'Rourke DM, Davuluri RV.

Nucleic Acids Res. 2014 Apr;42(8):e64. doi: 10.1093/nar/gku121. Epub 2014 Feb 6.

29.

The p130 isoform of angiomotin is required for Yap-mediated hepatic epithelial cell proliferation and tumorigenesis.

Yi C, Shen Z, Stemmer-Rachamimov A, Dawany N, Troutman S, Showe LC, Liu Q, Shimono A, Sudol M, Holmgren L, Stanger BZ, Kissil JL.

Sci Signal. 2013 Sep 3;6(291):ra77. doi: 10.1126/scisignal.2004060.

30.

Retraction: Sp100 as a potent tumor suppressor: accelerated senescence and rapid malignant transformation of human fibroblasts through modulation of an embryonic stem cell program.

Negorev DG, Vladimirova OV, Kossenkov AV, Demarest RM, Showe MK, Rauscher FJ 3rd, Showe LC, Nikonova EV, Capobianco AJ.

Cancer Res. 2013 Aug 1;73(15):4960-1. doi: 10.1158/0008-5472.CAN-13-1715. No abstract available.

31.

CD164 and FCRL3 are highly expressed on CD4+CD26- T cells in Sézary syndrome patients.

Wysocka M, Kossenkov AV, Benoit BM, Troxel AB, Singer E, Schaffer A, Kim B, Dentchev T, Nagata S, Ise T, Showe LC, Rook AH.

J Invest Dermatol. 2014 Jan;134(1):229-236. doi: 10.1038/jid.2013.279. Epub 2013 Jun 21.

32.

Single cell analysis of RNA-mediated histone H3.3 recruitment to a cytomegalovirus promoter-regulated transcription site.

Newhart A, Rafalska-Metcalf IU, Yang T, Joo LM, Powers SL, Kossenkov AV, Lopez-Jones M, Singer RH, Showe LC, Skordalakes E, Janicki SM.

J Biol Chem. 2013 Jul 5;288(27):19882-99. doi: 10.1074/jbc.M113.473181. Epub 2013 May 20.

33.

MAPK pathway activation leads to Bim loss and histone deacetylase inhibitor resistance: rationale to combine romidepsin with an MEK inhibitor.

Chakraborty AR, Robey RW, Luchenko VL, Zhan Z, Piekarz RL, Gillet JP, Kossenkov AV, Wilkerson J, Showe LC, Gottesman MM, Collie NL, Bates SE.

Blood. 2013 May 16;121(20):4115-25. doi: 10.1182/blood-2012-08-449140. Epub 2013 Mar 26.

34.

Cyclophilin D extramitochondrial signaling controls cell cycle progression and chemokine-directed cell motility.

Tavecchio M, Lisanti S, Lam A, Ghosh JC, Martin NM, O'Connell M, Weeraratna AT, Kossenkov AV, Showe LC, Altieri DC.

J Biol Chem. 2013 Feb 22;288(8):5553-61. doi: 10.1074/jbc.M112.433045. Epub 2013 Jan 9.

35.

Correlates of relative resistance against low-dose rectal simian immunodeficiency virus challenges in peripheral blood mononuclear cells of vaccinated rhesus macaques.

Kurupati R, Tuyishime S, Kossenkov AV, Sazanovich M, Haut LH, Lasaro MO, Ratcliffe SJ, Bosinger SE, Carnathan DG, Lewis M, Showe LC, Silvestri G, Ertl HC.

J Leukoc Biol. 2013 Mar;93(3):437-48. doi: 10.1189/jlb.0612287. Epub 2012 Dec 27.

36.

The peripheral immune response and lung cancer prognosis.

Showe MK, Kossenkov AV, Showe LC.

Oncoimmunology. 2012 Nov 1;1(8):1414-1416.

37.

Human breast cancer associated fibroblasts exhibit subtype specific gene expression profiles.

Tchou J, Kossenkov AV, Chang L, Satija C, Herlyn M, Showe LC, Puré E.

BMC Med Genomics. 2012 Sep 6;5:39. doi: 10.1186/1755-8794-5-39.

38.

Constitutive gene expression in monocytes from chronic HIV-1 infection overlaps with acute Toll-like receptor induced monocyte activation profiles.

Gekonge B, Giri MS, Kossenkov AV, Nebozyhn M, Yousef M, Mounzer K, Showe L, Montaner LJ.

PLoS One. 2012;7(7):e41153. doi: 10.1371/journal.pone.0041153. Epub 2012 Jul 18.

39.

Cohesins repress Kaposi's sarcoma-associated herpesvirus immediate early gene transcription during latency.

Chen HS, Wikramasinghe P, Showe L, Lieberman PM.

J Virol. 2012 Sep;86(17):9454-64. doi: 10.1128/JVI.00787-12. Epub 2012 Jun 27.

40.

Retinoblastoma protein induction by HIV viremia or CCR5 in monocytes exposed to HIV-1 mediates protection from activation-induced apoptosis: ex vivo and in vitro study.

Gekonge B, Raymond AD, Yin X, Kostman J, Mounzer K, Collman RG, Showe L, Montaner LJ.

J Leukoc Biol. 2012 Aug;92(2):397-405. doi: 10.1189/jlb.1111552. Epub 2012 Jun 13.

41.

Chk2 phosphorylation of survivin-DeltaEx3 contributes to a DNA damage-sensing checkpoint in cancer.

Lopergolo A, Tavecchio M, Lisanti S, Ghosh JC, Dohi T, Faversani A, Vaira V, Bosari S, Tanigawa N, Delia D, Kossenkov AV, Showe LC, Altieri DC.

Cancer Res. 2012 Jul 1;72(13):3251-9. doi: 10.1158/0008-5472.CAN-11-4035. Epub 2012 May 14.

42.

Gene expression profiling of flaxseed in mouse lung tissues-modulation of toxicologically relevant genes.

Dukes F, Kanterakis S, Lee J, Pietrofesa R, Andersen ES, Arguiri E, Tyagi S, Showe L, Amrani Y, Christofidou-Solomidou M.

BMC Complement Altern Med. 2012 Apr 20;12:47. doi: 10.1186/1472-6882-12-47.

43.

Peripheral immune cell gene expression predicts survival of patients with non-small cell lung cancer.

Kossenkov AV, Dawany N, Evans TL, Kucharczuk JC, Albelda SM, Showe LC, Showe MK, Vachani A.

PLoS One. 2012;7(3):e34392. doi: 10.1371/journal.pone.0034392. Epub 2012 Mar 29.

44.

The Rac1 splice form Rac1b promotes K-ras-induced lung tumorigenesis.

Zhou C, Licciulli S, Avila JL, Cho M, Troutman S, Jiang P, Kossenkov AV, Showe LC, Liu Q, Vachani A, Albelda SM, Kissil JL.

Oncogene. 2013 Feb 14;32(7):903-9. doi: 10.1038/onc.2012.99. Epub 2012 Mar 19.

45.

Identification of host-chromosome binding sites and candidate gene targets for Kaposi's sarcoma-associated herpesvirus LANA.

Lu F, Tsai K, Chen HS, Wikramasinghe P, Davuluri RV, Showe L, Domsic J, Marmorstein R, Lieberman PM.

J Virol. 2012 May;86(10):5752-62. doi: 10.1128/JVI.07216-11. Epub 2012 Mar 14.

46.

The histone deacetylase inhibitor, romidepsin, suppresses cellular immune functions of cutaneous T-cell lymphoma patients.

Kelly-Sell MJ, Kim YH, Straus S, Benoit B, Harrison C, Sutherland K, Armstrong R, Weng WK, Showe LC, Wysocka M, Rook AH.

Am J Hematol. 2012 Apr;87(4):354-60. doi: 10.1002/ajh.23112. Epub 2012 Feb 24.

47.

Preservation of bone mass and structure in hibernating black bears (Ursus americanus) through elevated expression of anabolic genes.

Fedorov VB, Goropashnaya AV, Tøien Ø, Stewart NC, Chang C, Wang H, Yan J, Showe LC, Showe MK, Donahue SW, Barnes BM.

Funct Integr Genomics. 2012 Jun;12(2):357-65. doi: 10.1007/s10142-012-0266-3. Epub 2012 Feb 18.

48.

Delta-aminolevulinate-induced host-parasite porphyric disparity for selective photolysis of transgenic Leishmania in the phagolysosomes of mononuclear phagocytes: a potential novel platform for vaccine delivery.

Dutta S, Chang C, Kolli BK, Sassa S, Yousef M, Showe M, Showe L, Chang KP.

Eukaryot Cell. 2012 Apr;11(4):430-41. doi: 10.1128/EC.05202-11. Epub 2012 Feb 3.

49.

Inhibition of cell-mediated immunity by the histone deacetylase inhibitor vorinostat: implications for therapy of cutaneous T-cell lymphoma.

Stephen S, Morrissey KA, Benoit BM, Kim EJ, Vittorio CC, Nasta SD, Showe LC, Wysocka M, Rook AH.

Am J Hematol. 2012 Feb;87(2):226-8. doi: 10.1002/ajh.22231. Epub 2011 Dec 21.

50.

Synergistic enhancement of cellular immune responses by the novel Toll receptor 7/8 agonist 3M-007 and interferon-γ: implications for therapy of cutaneous T-cell lymphoma.

Wysocka M, Dawany N, Benoit B, Kossenkov AV, Troxel AB, Gelfand JM, Sell MK, Showe LC, Rook AH.

Leuk Lymphoma. 2011 Oct;52(10):1970-9. doi: 10.3109/10428194.2011.582202.

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