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Items: 30

1.

Publisher Correction: Enhancer signatures stratify and predict outcomes of non-functional pancreatic neuroendocrine tumors.

Cejas P, Drier Y, Dreijerink KMA, Brosens LAA, Deshpande V, Epstein CB, Conemans EB, Morsink FHM, Graham MK, Valk GD, Vriens MR, Castillo CF, Ferrone CR, Adar T, Bowden M, Whitton HJ, Da Silva A, Font-Tello A, Long HW, Gaskell E, Shoresh N, Heaphy CM, Sicinska E, Kulke MH, Chung DC, Bernstein BE, Shivdasani RA.

Nat Med. 2019 Oct;25(10):1627. doi: 10.1038/s41591-019-0573-5.

PMID:
31501535
2.

Enhancer signatures stratify and predict outcomes of non-functional pancreatic neuroendocrine tumors.

Cejas P, Drier Y, Dreijerink KMA, Brosens LAA, Deshpande V, Epstein CB, Conemans EB, Morsink FHM, Graham MK, Valk GD, Vriens MR, Castillo CF, Ferrone CR, Adar T, Bowden M, Whitton HJ, Da Silva A, Font-Tello A, Long HW, Gaskell E, Shoresh N, Heaphy CM, Sicinska E, Kulke MH, Chung DC, Bernstein BE, Shivdasani RA.

Nat Med. 2019 Aug;25(8):1260-1265. doi: 10.1038/s41591-019-0493-4. Epub 2019 Jul 1. Erratum in: Nat Med. 2019 Oct;25(10):1627.

PMID:
31263286
3.

RNA sequence analysis reveals macroscopic somatic clonal expansion across normal tissues.

Yizhak K, Aguet F, Kim J, Hess JM, Kübler K, Grimsby J, Frazer R, Zhang H, Haradhvala NJ, Rosebrock D, Livitz D, Li X, Arich-Landkof E, Shoresh N, Stewart C, Segrè AV, Branton PA, Polak P, Ardlie KG, Getz G.

Science. 2019 Jun 7;364(6444). pii: eaaw0726. doi: 10.1126/science.aaw0726.

PMID:
31171663
4.

Defining the core essential genome of Pseudomonas aeruginosa.

Poulsen BE, Yang R, Clatworthy AE, White T, Osmulski SJ, Li L, Penaranda C, Lander ES, Shoresh N, Hung DT.

Proc Natl Acad Sci U S A. 2019 May 14;116(20):10072-10080. doi: 10.1073/pnas.1900570116. Epub 2019 Apr 29.

5.

Rapid identification and phylogenetic classification of diverse bacterial pathogens in a multiplexed hybridization assay targeting ribosomal RNA.

Bhattacharyya RP, Walker M, Boykin R, Son SS, Liu J, Hachey AC, Ma P, Wu L, Choi K, Cummins KC, Benson M, Skerry J, Ryu H, Wong SY, Goldberg MB, Han J, Pierce VM, Cosimi LA, Shoresh N, Livny J, Beechem J, Hung DT.

Sci Rep. 2019 Mar 14;9(1):4516. doi: 10.1038/s41598-019-40792-3.

6.

Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types.

Finucane HK, Reshef YA, Anttila V, Slowikowski K, Gusev A, Byrnes A, Gazal S, Loh PR, Lareau C, Shoresh N, Genovese G, Saunders A, Macosko E, Pollack S; Brainstorm Consortium, Perry JRB, Buenrostro JD, Bernstein BE, Raychaudhuri S, McCarroll S, Neale BM, Price AL.

Nat Genet. 2018 Apr;50(4):621-629. doi: 10.1038/s41588-018-0081-4. Epub 2018 Apr 9.

7.

A Genetic Variant Associated with Five Vascular Diseases Is a Distal Regulator of Endothelin-1 Gene Expression.

Gupta RM, Hadaya J, Trehan A, Zekavat SM, Roselli C, Klarin D, Emdin CA, Hilvering CRE, Bianchi V, Mueller C, Khera AV, Ryan RJH, Engreitz JM, Issner R, Shoresh N, Epstein CB, de Laat W, Brown JD, Schnabel RB, Bernstein BE, Kathiresan S.

Cell. 2017 Jul 27;170(3):522-533.e15. doi: 10.1016/j.cell.2017.06.049.

8.

An Experimental Framework for Quantifying Bacterial Tolerance.

Brauner A, Shoresh N, Fridman O, Balaban NQ.

Biophys J. 2017 Jun 20;112(12):2664-2671. doi: 10.1016/j.bpj.2017.05.014.

9.

Antibiotic tolerance facilitates the evolution of resistance.

Levin-Reisman I, Ronin I, Gefen O, Braniss I, Shoresh N, Balaban NQ.

Science. 2017 Feb 24;355(6327):826-830. doi: 10.1126/science.aaj2191. Epub 2017 Feb 9.

PMID:
28183996
10.

Single-molecule decoding of combinatorially modified nucleosomes.

Shema E, Jones D, Shoresh N, Donohue L, Ram O, Bernstein BE.

Science. 2016 May 6;352(6286):717-21. doi: 10.1126/science.aad7701.

11.

Single-cell ChIP-seq reveals cell subpopulations defined by chromatin state.

Rotem A, Ram O, Shoresh N, Sperling RA, Goren A, Weitz DA, Bernstein BE.

Nat Biotechnol. 2015 Nov;33(11):1165-72. doi: 10.1038/nbt.3383. Epub 2015 Oct 12.

12.

High-Throughput Single-Cell Labeling (Hi-SCL) for RNA-Seq Using Drop-Based Microfluidics.

Rotem A, Ram O, Shoresh N, Sperling RA, Schnall-Levin M, Zhang H, Basu A, Bernstein BE, Weitz DA.

PLoS One. 2015 May 22;10(5):e0116328. doi: 10.1371/journal.pone.0116328. eCollection 2015.

13.

Polyploidy can drive rapid adaptation in yeast.

Selmecki AM, Maruvka YE, Richmond PA, Guillet M, Shoresh N, Sorenson AL, De S, Kishony R, Michor F, Dowell R, Pellman D.

Nature. 2015 Mar 19;519(7543):349-52. doi: 10.1038/nature14187. Epub 2015 Mar 2.

14.

Integrative analysis of 111 reference human epigenomes.

Roadmap Epigenomics Consortium, Kundaje A, Meuleman W, Ernst J, Bilenky M, Yen A, Heravi-Moussavi A, Kheradpour P, Zhang Z, Wang J, Ziller MJ, Amin V, Whitaker JW, Schultz MD, Ward LD, Sarkar A, Quon G, Sandstrom RS, Eaton ML, Wu YC, Pfenning AR, Wang X, Claussnitzer M, Liu Y, Coarfa C, Harris RA, Shoresh N, Epstein CB, Gjoneska E, Leung D, Xie W, Hawkins RD, Lister R, Hong C, Gascard P, Mungall AJ, Moore R, Chuah E, Tam A, Canfield TK, Hansen RS, Kaul R, Sabo PJ, Bansal MS, Carles A, Dixon JR, Farh KH, Feizi S, Karlic R, Kim AR, Kulkarni A, Li D, Lowdon R, Elliott G, Mercer TR, Neph SJ, Onuchic V, Polak P, Rajagopal N, Ray P, Sallari RC, Siebenthall KT, Sinnott-Armstrong NA, Stevens M, Thurman RE, Wu J, Zhang B, Zhou X, Beaudet AE, Boyer LA, De Jager PL, Farnham PJ, Fisher SJ, Haussler D, Jones SJ, Li W, Marra MA, McManus MT, Sunyaev S, Thomson JA, Tlsty TD, Tsai LH, Wang W, Waterland RA, Zhang MQ, Chadwick LH, Bernstein BE, Costello JF, Ecker JR, Hirst M, Meissner A, Milosavljevic A, Ren B, Stamatoyannopoulos JA, Wang T, Kellis M.

Nature. 2015 Feb 19;518(7539):317-30. doi: 10.1038/nature14248.

15.

Genetic and epigenetic fine mapping of causal autoimmune disease variants.

Farh KK, Marson A, Zhu J, Kleinewietfeld M, Housley WJ, Beik S, Shoresh N, Whitton H, Ryan RJ, Shishkin AA, Hatan M, Carrasco-Alfonso MJ, Mayer D, Luckey CJ, Patsopoulos NA, De Jager PL, Kuchroo VK, Epstein CB, Daly MJ, Hafler DA, Bernstein BE.

Nature. 2015 Feb 19;518(7539):337-43. doi: 10.1038/nature13835. Epub 2014 Oct 29.

16.

Comparative analysis of metazoan chromatin organization.

Ho JW, Jung YL, Liu T, Alver BH, Lee S, Ikegami K, Sohn KA, Minoda A, Tolstorukov MY, Appert A, Parker SC, Gu T, Kundaje A, Riddle NC, Bishop E, Egelhofer TA, Hu SS, Alekseyenko AA, Rechtsteiner A, Asker D, Belsky JA, Bowman SK, Chen QB, Chen RA, Day DS, Dong Y, Dose AC, Duan X, Epstein CB, Ercan S, Feingold EA, Ferrari F, Garrigues JM, Gehlenborg N, Good PJ, Haseley P, He D, Herrmann M, Hoffman MM, Jeffers TE, Kharchenko PV, Kolasinska-Zwierz P, Kotwaliwale CV, Kumar N, Langley SA, Larschan EN, Latorre I, Libbrecht MW, Lin X, Park R, Pazin MJ, Pham HN, Plachetka A, Qin B, Schwartz YB, Shoresh N, Stempor P, Vielle A, Wang C, Whittle CM, Xue H, Kingston RE, Kim JH, Bernstein BE, Dernburg AF, Pirrotta V, Kuroda MI, Noble WS, Tullius TD, Kellis M, MacAlpine DM, Strome S, Elgin SC, Liu XS, Lieb JD, Ahringer J, Karpen GH, Park PJ.

Nature. 2014 Aug 28;512(7515):449-52. doi: 10.1038/nature13415.

17.

Optimization of lag time underlies antibiotic tolerance in evolved bacterial populations.

Fridman O, Goldberg A, Ronin I, Shoresh N, Balaban NQ.

Nature. 2014 Sep 18;513(7518):418-21. doi: 10.1038/nature13469. Epub 2014 Jun 25.

PMID:
25043002
18.

In silico abstraction of zinc finger nuclease cleavage profiles reveals an expanded landscape of off-target sites.

Sander JD, Ramirez CL, Linder SJ, Pattanayak V, Shoresh N, Ku M, Foden JA, Reyon D, Bernstein BE, Liu DR, Joung JK.

Nucleic Acids Res. 2013 Oct;41(19):e181. doi: 10.1093/nar/gkt716. Epub 2013 Aug 14.

19.

Genome-wide chromatin state transitions associated with developmental and environmental cues.

Zhu J, Adli M, Zou JY, Verstappen G, Coyne M, Zhang X, Durham T, Miri M, Deshpande V, De Jager PL, Bennett DA, Houmard JA, Muoio DM, Onder TT, Camahort R, Cowan CA, Meissner A, Epstein CB, Shoresh N, Bernstein BE.

Cell. 2013 Jan 31;152(3):642-54. doi: 10.1016/j.cell.2012.12.033. Epub 2013 Jan 17.

20.

ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia.

Landt SG, Marinov GK, Kundaje A, Kheradpour P, Pauli F, Batzoglou S, Bernstein BE, Bickel P, Brown JB, Cayting P, Chen Y, DeSalvo G, Epstein C, Fisher-Aylor KI, Euskirchen G, Gerstein M, Gertz J, Hartemink AJ, Hoffman MM, Iyer VR, Jung YL, Karmakar S, Kellis M, Kharchenko PV, Li Q, Liu T, Liu XS, Ma L, Milosavljevic A, Myers RM, Park PJ, Pazin MJ, Perry MD, Raha D, Reddy TE, Rozowsky J, Shoresh N, Sidow A, Slattery M, Stamatoyannopoulos JA, Tolstorukov MY, White KP, Xi S, Farnham PJ, Lieb JD, Wold BJ, Snyder M.

Genome Res. 2012 Sep;22(9):1813-31. doi: 10.1101/gr.136184.111.

21.

Points of view: Data exploration.

Shoresh N, Wong B.

Nat Methods. 2012 Jan;9(1):5. No abstract available.

PMID:
22312636
22.

Combinatorial patterning of chromatin regulators uncovered by genome-wide location analysis in human cells.

Ram O, Goren A, Amit I, Shoresh N, Yosef N, Ernst J, Kellis M, Gymrek M, Issner R, Coyne M, Durham T, Zhang X, Donaghey J, Epstein CB, Regev A, Bernstein BE.

Cell. 2011 Dec 23;147(7):1628-39. doi: 10.1016/j.cell.2011.09.057.

23.

Mapping and analysis of chromatin state dynamics in nine human cell types.

Ernst J, Kheradpour P, Mikkelsen TS, Shoresh N, Ward LD, Epstein CB, Zhang X, Wang L, Issner R, Coyne M, Ku M, Durham T, Kellis M, Bernstein BE.

Nature. 2011 May 5;473(7345):43-9. doi: 10.1038/nature09906. Epub 2011 Mar 23.

24.

Regulation of phenotypic variability by a threshold-based mechanism underlies bacterial persistence.

Rotem E, Loinger A, Ronin I, Levin-Reisman I, Gabay C, Shoresh N, Biham O, Balaban NQ.

Proc Natl Acad Sci U S A. 2010 Jul 13;107(28):12541-6. doi: 10.1073/pnas.1004333107. Epub 2010 Jun 28.

25.

Chromatin profiling by directly sequencing small quantities of immunoprecipitated DNA.

Goren A, Ozsolak F, Shoresh N, Ku M, Adli M, Hart C, Gymrek M, Zuk O, Regev A, Milos PM, Bernstein BE.

Nat Methods. 2010 Jan;7(1):47-9. doi: 10.1038/nmeth.1404. Epub 2009 Nov 29.

26.

Accelerated evolution of resistance in multidrug environments.

Hegreness M, Shoresh N, Damian D, Hartl D, Kishony R.

Proc Natl Acad Sci U S A. 2008 Sep 16;105(37):13977-81. doi: 10.1073/pnas.0805965105. Epub 2008 Sep 8.

27.

Evolution exacerbates the paradox of the plankton.

Shoresh N, Hegreness M, Kishony R.

Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12365-9. doi: 10.1073/pnas.0803032105. Epub 2008 Aug 19.

28.

Exposing the fitness contribution of duplicated genes.

DeLuna A, Vetsigian K, Shoresh N, Hegreness M, Colón-González M, Chao S, Kishony R.

Nat Genet. 2008 May;40(5):676-81. doi: 10.1038/ng.123. Epub 2008 Apr 13.

PMID:
18408719
29.

Analytical results for individual and group selection of any intensity.

Traulsen A, Shoresh N, Nowak MA.

Bull Math Biol. 2008 Jul;70(5):1410-24. doi: 10.1007/s11538-008-9305-6. Epub 2008 Apr 2.

30.

An equivalence principle for the incorporation of favorable mutations in asexual populations.

Hegreness M, Shoresh N, Hartl D, Kishony R.

Science. 2006 Mar 17;311(5767):1615-7.

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